Calculation Parameters
| Chain Sequence(s) |
QMQLQESGPGLVKPSETLSLTCSVSGASISDSYWSWIRRSPGKGLEWIGYVHKSGDTNYSPSLKSRVNLSLDTSKNQVSLSLVAATAADSGKYYCARTLHGRRIYGIVAFNEWFTYFYMDVWGNGTQVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPISVAPGETARISCGEKSLGSRAVQWYQHRAGQAPSLIIYNNQDRPSGIPERFSGSPDSPFGTTATLTITSVEAGDEADYYCHIWDSRVPTKWVFGGGTTLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTE
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.6527 | Soluble |
| 2 | M | B | -1.3290 | Soluble |
| 3 | Q | B | -2.0566 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | Q | B | -1.9235 | Soluble |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.9311 | Soluble |
| 8 | G | B | -0.6230 | Soluble |
| 9 | P | B | -0.3797 | Soluble |
| 11 | G | B | -0.4847 | Soluble |
| 12 | L | B | -0.0665 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | K | B | -1.8899 | Soluble |
| 15 | P | B | -1.1704 | Soluble |
| 16 | S | B | -1.0772 | Soluble |
| 17 | E | B | -1.6975 | Soluble |
| 18 | T | B | -0.6575 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | S | B | -0.4649 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | T | B | -0.5303 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | S | B | -1.2563 | Soluble |
| 25 | V | B | 0.0000 | Buried |
| 26 | S | B | -1.3313 | Soluble |
| 27 | G | B | -1.2568 | Soluble |
| 28 | A | B | -1.1983 | Soluble |
| 29 | S | B | -1.0690 | Soluble |
| 30 | I | B | 0.0000 | Buried |
| 35 | S | B | -1.6430 | Soluble |
| 36 | D | B | -2.1385 | Soluble |
| 37 | S | B | 0.0000 | Buried |
| 38 | Y | B | -0.8383 | Soluble |
| 39 | W | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | I | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | R | B | -1.4256 | Soluble |
| 45 | S | B | -1.4406 | Soluble |
| 46 | P | B | -1.2318 | Soluble |
| 47 | G | B | -1.5477 | Soluble |
| 48 | K | B | -2.1238 | Soluble |
| 49 | G | B | -1.3767 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.1924 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | I | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | Y | B | 0.0000 | Buried |
| 56 | V | B | 0.0000 | Buried |
| 57 | H | B | -1.6677 | Soluble |
| 58 | K | B | -2.4314 | Soluble |
| 59 | S | B | -1.5344 | Soluble |
| 63 | G | B | -1.5168 | Soluble |
| 64 | D | B | -1.3801 | Soluble |
| 65 | T | B | -1.1309 | Soluble |
| 66 | N | B | -1.1137 | Soluble |
| 67 | Y | B | -1.0617 | Soluble |
| 68 | S | B | 0.0000 | Buried |
| 69 | P | B | -1.0942 | Soluble |
| 70 | S | B | -0.8656 | Soluble |
| 71 | L | B | 0.0000 | Buried |
| 72 | K | B | -2.2676 | Soluble |
| 74 | S | B | -1.3075 | Soluble |
| 75 | R | B | -0.9950 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | N | B | -1.6223 | Soluble |
| 78 | L | B | 0.0000 | Buried |
| 79 | S | B | -0.7442 | Soluble |
| 80 | L | B | -0.8182 | Soluble |
| 81 | D | B | -1.3695 | Soluble |
| 82 | T | B | -1.2952 | Soluble |
| 83 | S | B | -1.3159 | Soluble |
| 84 | K | B | -2.1396 | Soluble |
| 85 | N | B | -1.5032 | Soluble |
| 86 | Q | B | -1.2950 | Soluble |
| 87 | V | B | 0.0000 | Buried |
| 88 | S | B | -0.4807 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | S | B | -0.4193 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | V | B | 0.1901 | Aggregation-prone |
| 93 | A | B | -0.3109 | Soluble |
| 94 | A | B | 0.0000 | Buried |
| 95 | T | B | -0.4320 | Soluble |
| 96 | A | B | -0.2164 | Soluble |
| 97 | A | B | -0.0640 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | S | B | -0.4608 | Soluble |
| 100 | G | B | 0.0000 | Buried |
| 101 | K | B | -1.5784 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | -0.5769 | Soluble |
| 107 | T | B | 0.0000 | Buried |
| 108 | L | B | -0.2184 | Soluble |
| 109 | H | B | -1.0585 | Soluble |
| 110 | G | B | -1.1838 | Soluble |
| 111 | R | B | -1.6117 | Soluble |
| 111A | R | B | -0.5461 | Soluble |
| 111B | I | B | 1.0954 | Aggregation-prone |
| 111C | Y | B | 0.8984 | Aggregation-prone |
| 111D | G | B | 1.3466 | Aggregation-prone |
| 111E | I | B | 2.5532 | Aggregation-prone |
| 111F | V | B | 1.8774 | Aggregation-prone |
| 112G | A | B | 1.4717 | Aggregation-prone |
| 112F | F | B | 1.9660 | Aggregation-prone |
| 112E | N | B | 0.4796 | Aggregation-prone |
| 112D | E | B | 0.8250 | Aggregation-prone |
| 112C | W | B | 0.6632 | Aggregation-prone |
| 112B | F | B | -0.2120 | Soluble |
| 112A | T | B | -0.7277 | Soluble |
| 112 | Y | B | 0.0000 | Buried |
| 113 | F | B | 0.0000 | Buried |
| 114 | Y | B | -0.0479 | Soluble |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | -0.3021 | Soluble |
| 117 | V | B | -0.3148 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | N | B | -2.1884 | Soluble |
| 121 | G | B | -1.6348 | Soluble |
| 122 | T | B | -1.3759 | Soluble |
| 123 | Q | B | -1.5645 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.4442 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.5560 | Soluble |
| 128 | S | B | -0.7522 | Soluble |
| 129 | A | B | -0.5665 | Soluble |
| 130 | S | B | -0.7159 | Soluble |
| 131 | T | B | -0.7197 | Soluble |
| 132 | K | B | -1.1360 | Soluble |
| 133 | G | B | -1.2331 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.2849 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.0387 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.8563 | Soluble |
| 141 | P | B | -0.7109 | Soluble |
| 142 | S | B | -0.7279 | Soluble |
| 143 | S | B | -1.3271 | Soluble |
| 144 | K | B | -1.9764 | Soluble |
| 145 | S | B | -1.1275 | Soluble |
| 146 | T | B | -0.8985 | Soluble |
| 147 | S | B | -0.8965 | Soluble |
| 148 | G | B | -1.0997 | Soluble |
| 149 | G | B | -0.9363 | Soluble |
| 150 | T | B | -0.8837 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | -0.6500 | Soluble |
| 163 | E | B | -1.0382 | Soluble |
| 164 | P | B | -1.0036 | Soluble |
| 165 | V | B | -0.8137 | Soluble |
| 166 | T | B | -0.6759 | Soluble |
| 167 | V | B | -0.4322 | Soluble |
| 168 | S | B | -0.3866 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.8626 | Soluble |
| 171 | S | B | -0.6204 | Soluble |
| 172 | G | B | -0.4000 | Soluble |
| 173 | A | B | -0.1865 | Soluble |
| 174 | L | B | -0.0219 | Soluble |
| 175 | T | B | -0.2170 | Soluble |
| 176 | S | B | -0.3194 | Soluble |
| 177 | G | B | -0.3983 | Soluble |
| 178 | V | B | 0.0856 | Aggregation-prone |
| 179 | H | B | -0.1805 | Soluble |
| 180 | T | B | -0.0689 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.0482 | Soluble |
| 183 | A | B | 0.1580 | Aggregation-prone |
| 184 | V | B | 0.0000 | Buried |
| 185 | L | B | 1.0287 | Aggregation-prone |
| 186 | Q | B | 0.3367 | Aggregation-prone |
| 187 | S | B | -0.0858 | Soluble |
| 188 | S | B | -0.1120 | Soluble |
| 189 | G | B | 0.0832 | Aggregation-prone |
| 190 | L | B | 0.1359 | Aggregation-prone |
| 191 | Y | B | 0.2849 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.2882 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.7712 | Soluble |
| 201 | S | B | -0.7139 | Soluble |
| 202 | S | B | -0.6433 | Soluble |
| 203 | S | B | -0.7152 | Soluble |
| 204 | L | B | -0.8267 | Soluble |
| 205 | G | B | -0.9812 | Soluble |
| 206 | T | B | -0.7902 | Soluble |
| 207 | Q | B | -1.3809 | Soluble |
| 208 | T | B | -1.2353 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.4461 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.6087 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -1.9585 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8408 | Soluble |
| 217 | P | B | -1.7126 | Soluble |
| 218 | S | B | -1.9116 | Soluble |
| 219 | N | B | -2.5690 | Soluble |
| 220 | T | B | -2.2815 | Soluble |
| 221 | K | B | -2.7744 | Soluble |
| 222 | V | B | -1.8530 | Soluble |
| 223 | D | B | -2.6339 | Soluble |
| 224 | K | B | -2.2335 | Soluble |
| 225 | R | B | -2.7275 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.5244 | Soluble |
| 228 | P | B | -1.3437 | Soluble |
| 11 | I | A | 1.6288 | Aggregation-prone |
| 12 | S | A | 0.5693 | Aggregation-prone |
| 13 | V | A | 0.0000 | Buried |
| 14 | A | A | -1.1177 | Soluble |
| 15 | P | A | -1.7492 | Soluble |
| 16 | G | A | -1.8980 | Soluble |
| 17 | E | A | -2.5298 | Soluble |
| 18 | T | A | -1.7745 | Soluble |
| 19 | A | A | 0.0000 | Buried |
| 20 | R | A | -1.8711 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | S | A | -1.0918 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | G | A | -1.3503 | Soluble |
| 25 | E | A | -1.6440 | Soluble |
| 26 | K | A | -1.6805 | Soluble |
| 27 | S | A | 0.0000 | Buried |
| 28 | L | A | 0.2766 | Aggregation-prone |
| 29 | G | A | 0.0000 | Buried |
| 36 | S | A | 0.0000 | Buried |
| 37 | R | A | 0.0000 | Buried |
| 38 | A | A | 0.0000 | Buried |
| 39 | V | A | 0.0000 | Buried |
| 40 | Q | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | H | A | 0.0000 | Buried |
| 45 | R | A | -1.1636 | Soluble |
| 46 | A | A | -0.8095 | Soluble |
| 47 | G | A | -1.2053 | Soluble |
| 48 | Q | A | -1.5772 | Soluble |
| 49 | A | A | -1.1131 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | S | A | -0.2614 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | I | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | -0.6718 | Soluble |
| 56 | N | A | -1.2851 | Soluble |
| 57 | N | A | 0.0000 | Buried |
| 65 | Q | A | -1.8079 | Soluble |
| 66 | D | A | -1.4585 | Soluble |
| 67 | R | A | -1.7312 | Soluble |
| 68 | P | A | -0.8498 | Soluble |
| 69 | S | A | -0.6544 | Soluble |
| 70 | G | A | -0.7955 | Soluble |
| 71 | I | A | -0.7879 | Soluble |
| 72 | P | A | -1.2399 | Soluble |
| 74 | E | A | -2.1548 | Soluble |
| 75 | R | A | -1.5059 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -1.4023 | Soluble |
| 78 | G | A | -1.1889 | Soluble |
| 79 | S | A | -0.9220 | Soluble |
| 80 | P | A | -0.9242 | Soluble |
| 81 | D | A | -0.3784 | Soluble |
| 82 | S | A | 0.2414 | Aggregation-prone |
| 82A | P | A | 0.3666 | Aggregation-prone |
| 83 | F | A | 1.5602 | Aggregation-prone |
| 84 | G | A | 0.1303 | Aggregation-prone |
| 85 | T | A | -0.3135 | Soluble |
| 86 | T | A | -0.8380 | Soluble |
| 87 | A | A | 0.0000 | Buried |
| 88 | T | A | -0.8085 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.9558 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | T | A | -1.5981 | Soluble |
| 93 | S | A | -1.5019 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | E | A | -2.4847 | Soluble |
| 96 | A | A | -1.2595 | Soluble |
| 97 | G | A | -1.1281 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | E | A | -0.8437 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | D | A | -0.5740 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | H | A | 0.0000 | Buried |
| 106 | I | A | 0.0000 | Buried |
| 107 | W | A | 0.0000 | Buried |
| 108 | D | A | 0.0000 | Buried |
| 109 | S | A | -0.6448 | Soluble |
| 110 | R | A | -1.6168 | Soluble |
| 112 | V | A | -0.8164 | Soluble |
| 113 | P | A | -0.7121 | Soluble |
| 114 | T | A | -0.3518 | Soluble |
| 115 | K | A | -0.1354 | Soluble |
| 116 | W | A | 0.3915 | Aggregation-prone |
| 117 | V | A | 0.7082 | Aggregation-prone |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | -0.5742 | Soluble |
| 120 | G | A | -0.8246 | Soluble |
| 121 | G | A | -0.8286 | Soluble |
| 122 | T | A | -0.0153 | Soluble |
| 123 | T | A | 0.1017 | Aggregation-prone |
| 124 | L | A | 0.0000 | Buried |
| 125 | T | A | 0.0703 | Aggregation-prone |
| 126 | V | A | 0.0000 | Buried |
| 127 | L | A | -0.6389 | Soluble |
| 128 | G | A | -1.1691 | Soluble |
| 129 | Q | A | -1.0722 | Soluble |
| 130 | P | A | -1.2482 | Soluble |
| 131 | K | A | -2.2932 | Soluble |
| 132 | A | A | -1.3790 | Soluble |
| 133 | A | A | -0.8451 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.2461 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | T | A | -0.5909 | Soluble |
| 138 | L | A | 0.0000 | Buried |
| 139 | F | A | 0.0000 | Buried |
| 140 | P | A | -0.2668 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.9931 | Soluble |
| 143 | S | A | -1.5737 | Soluble |
| 144 | E | A | -2.1469 | Soluble |
| 145 | E | A | 0.0000 | Buried |
| 146 | L | A | -2.0109 | Soluble |
| 147 | Q | A | -2.2066 | Soluble |
| 148 | A | A | -1.7300 | Soluble |
| 149 | N | A | -2.4082 | Soluble |
| 150 | K | A | -2.0133 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | T | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | V | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | I | A | 0.0000 | Buried |
| 158 | S | A | -0.6704 | Soluble |
| 159 | D | A | -1.6284 | Soluble |
| 160 | F | A | 0.0000 | Buried |
| 161 | Y | A | 0.0000 | Buried |
| 162 | P | A | -1.3010 | Soluble |
| 163 | G | A | -1.0101 | Soluble |
| 164 | A | A | -0.2269 | Soluble |
| 165 | V | A | -0.2020 | Soluble |
| 166 | T | A | -0.1616 | Soluble |
| 167 | V | A | 0.0420 | Aggregation-prone |
| 168 | A | A | -0.4006 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | K | A | -1.2938 | Soluble |
| 171 | A | A | 0.0000 | Buried |
| 172 | D | A | -1.8566 | Soluble |
| 173 | S | A | -1.1862 | Soluble |
| 174 | S | A | -0.9749 | Soluble |
| 175 | P | A | -1.0047 | Soluble |
| 176 | V | A | -0.8967 | Soluble |
| 177 | K | A | -1.5909 | Soluble |
| 178 | A | A | -0.7045 | Soluble |
| 179 | G | A | -0.3764 | Soluble |
| 180 | V | A | -0.1491 | Soluble |
| 181 | E | A | 0.0579 | Aggregation-prone |
| 182 | T | A | 0.1269 | Aggregation-prone |
| 183 | T | A | 0.0000 | Buried |
| 184 | T | A | -0.0043 | Soluble |
| 185 | P | A | -0.4356 | Soluble |
| 186 | S | A | -1.0377 | Soluble |
| 187 | K | A | -2.2813 | Soluble |
| 188 | Q | A | -1.9139 | Soluble |
| 189 | S | A | -1.6986 | Soluble |
| 190 | N | A | -2.3034 | Soluble |
| 191 | N | A | -2.6971 | Soluble |
| 192 | K | A | -2.3471 | Soluble |
| 193 | Y | A | -1.4394 | Soluble |
| 194 | A | A | 0.0000 | Buried |
| 195 | A | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | Y | A | 0.0000 | Buried |
| 199 | L | A | 0.0000 | Buried |
| 200 | S | A | -0.3177 | Soluble |
| 201 | L | A | 0.0000 | Buried |
| 202 | T | A | -1.7191 | Soluble |
| 203 | P | A | -2.3750 | Soluble |
| 204 | E | A | -3.1197 | Soluble |
| 205 | Q | A | -2.2996 | Soluble |
| 206 | W | A | 0.0000 | Buried |
| 207 | K | A | -3.0291 | Soluble |
| 208 | S | A | -2.4861 | Soluble |
| 209 | H | A | -2.5057 | Soluble |
| 210 | K | A | -2.5305 | Soluble |
| 211 | S | A | -1.6736 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | S | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | Q | A | -0.8456 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -0.6669 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | E | A | -2.3566 | Soluble |
| 220 | G | A | -1.4549 | Soluble |
| 221 | S | A | -0.8774 | Soluble |
| 222 | T | A | -0.7093 | Soluble |
| 223 | V | A | -0.4052 | Soluble |
| 224 | E | A | -1.4968 | Soluble |
| 225 | K | A | -1.1869 | Soluble |
| 226 | T | A | -0.6884 | Soluble |
| 227 | V | A | -0.5380 | Soluble |
| 228 | A | A | -1.3288 | Soluble |
| 229 | P | A | 0.0000 | Buried |
| 230 | T | A | -1.4838 | Soluble |
| 231 | E | A | -1.8522 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.5884 | 5.1281 | CSV PDB |
| 4.5 | -0.6236 | 5.1012 | CSV PDB |
| 5.0 | -0.6642 | 5.0621 | CSV PDB |
| 5.5 | -0.7 | 5.0172 | CSV PDB |
| 6.0 | -0.7199 | 4.9737 | CSV PDB |
| 6.5 | -0.7158 | 4.9386 | CSV PDB |
| 7.0 | -0.6893 | 4.917 | CSV PDB |
| 7.5 | -0.6493 | 4.9072 | CSV PDB |
| 8.0 | -0.6031 | 4.9036 | CSV PDB |
| 8.5 | -0.5532 | 4.9024 | CSV PDB |
| 9.0 | -0.5005 | 4.902 | CSV PDB |