Elipovimab

A4DAB100 | Phase-I
HIV-1 gp120
G1 / None
Gilead Sciences
Phase-I
Whole mAb
GS-9722 GS9722
—
Avg A4D Score
-0.6406
Score Range
-0.66 to -0.62
Structures
6
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB100_7uoj_h_l 7uoj 96% -0.6173 7.0 4.0 -0.2808 -0.7366
A4DAB100_4jy4_B_A 4jy4 96% -0.6547 6.0 9.0 -0.281 -0.7162
A4DAB100_7uoj_k_m 7uoj 96% -0.6455 7.0 4.0 -0.3255 -0.7589
A4DAB100_4fqc_H_L 4fqc 96% -0.6352 6.0 9.0 -0.2187 -0.7051
A4DAB100_7uoj_d_e 7uoj 96% -0.6614 7.0 4.0 -0.3922 -0.7568
A4DAB100_4fq1_H_L 4fq1 96% -0.6293 6.5 9.0 -0.1961 -0.7011