Calculation Parameters
| Chain Sequence(s) |
EVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPDILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1301 | Soluble |
| 2 | V | A | -1.2480 | Soluble |
| 3 | K | A | -1.9198 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | E | A | -1.6442 | Soluble |
| 6 | E | A | -0.9194 | Soluble |
| 7 | S | A | -0.7698 | Soluble |
| 8 | G | A | -0.8236 | Soluble |
| 9 | G | A | -0.6155 | Soluble |
| 11 | G | A | 0.0000 | Buried |
| 12 | L | A | -0.2494 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.8597 | Soluble |
| 15 | P | A | -1.9887 | Soluble |
| 16 | G | A | -2.0340 | Soluble |
| 17 | G | A | -1.4969 | Soluble |
| 18 | S | A | -1.3748 | Soluble |
| 19 | M | A | -1.0515 | Soluble |
| 20 | K | A | -1.4541 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4729 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | V | A | -0.1050 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.7684 | Soluble |
| 27 | G | A | -0.7967 | Soluble |
| 28 | F | A | 0.4223 | Aggregation-prone |
| 29 | I | A | 1.6056 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.6692 | Soluble |
| 36 | N | A | -0.7314 | Soluble |
| 37 | H | A | -0.0570 | Soluble |
| 38 | W | A | -0.0748 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.8080 | Soluble |
| 45 | S | A | -1.5648 | Soluble |
| 46 | P | A | -1.6753 | Soluble |
| 47 | E | A | -3.0895 | Soluble |
| 48 | K | A | -3.0319 | Soluble |
| 49 | G | A | -1.6713 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6711 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | E | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | R | A | -0.7080 | Soluble |
| 58 | S | A | 0.0000 | Buried |
| 59 | K | A | -2.1974 | Soluble |
| 60 | S | A | -0.9565 | Soluble |
| 61 | I | A | 0.0278 | Aggregation-prone |
| 62 | N | A | -1.3070 | Soluble |
| 63 | S | A | -1.1766 | Soluble |
| 64 | A | A | -0.5854 | Soluble |
| 65 | T | A | -0.4122 | Soluble |
| 66 | H | A | -0.7976 | Soluble |
| 67 | Y | A | -1.1283 | Soluble |
| 68 | A | A | -1.3872 | Soluble |
| 69 | E | A | -2.5049 | Soluble |
| 70 | S | A | -1.6749 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5712 | Soluble |
| 74 | G | A | -1.7593 | Soluble |
| 75 | R | A | 0.0000 | Buried |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.7873 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.4322 | Soluble |
| 80 | R | A | -0.9517 | Soluble |
| 81 | D | A | -1.4184 | Soluble |
| 82 | D | A | -1.4918 | Soluble |
| 83 | S | A | -1.4548 | Soluble |
| 84 | K | A | -1.9585 | Soluble |
| 85 | S | A | -0.6733 | Soluble |
| 86 | A | A | 0.0000 | Buried |
| 87 | V | A | 0.0000 | Buried |
| 88 | Y | A | -0.2786 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.1081 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | T | A | -1.5918 | Soluble |
| 93 | D | A | -2.5368 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.5280 | Soluble |
| 96 | T | A | -1.7915 | Soluble |
| 97 | E | A | -2.6939 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.8012 | Soluble |
| 100 | G | A | 0.0000 | Buried |
| 101 | V | A | 0.2172 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | N | A | 0.0000 | Buried |
| 108 | Y | A | 1.4327 | Aggregation-prone |
| 109 | Y | A | 1.1566 | Aggregation-prone |
| 110 | G | A | 0.6193 | Aggregation-prone |
| 113 | S | A | 0.0000 | Buried |
| 114 | T | A | 0.0000 | Buried |
| 115 | Y | A | 0.0000 | Buried |
| 116 | D | A | 0.1397 | Aggregation-prone |
| 117 | Y | A | 0.4050 | Aggregation-prone |
| 118 | W | A | -0.4430 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.8800 | Soluble |
| 121 | G | A | -1.0031 | Soluble |
| 122 | T | A | -0.5108 | Soluble |
| 123 | T | A | -0.1657 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | T | A | -0.5642 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.9996 | Soluble |
| 128 | S | A | -0.7579 | Soluble |
| 129 | A | A | -0.5402 | Soluble |
| 130 | S | A | -0.6914 | Soluble |
| 131 | T | A | -0.7778 | Soluble |
| 132 | K | A | -1.5246 | Soluble |
| 133 | G | A | -1.6196 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3476 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.4598 | Soluble |
| 138 | P | A | -0.8511 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8376 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.8125 | Soluble |
| 143 | S | A | -0.8248 | Soluble |
| 144 | K | A | -1.1622 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.7423 | Soluble |
| 147 | S | A | -0.7100 | Soluble |
| 148 | G | A | -0.8369 | Soluble |
| 149 | G | A | -0.8774 | Soluble |
| 150 | T | A | -0.5859 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5338 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.4961 | Soluble |
| 164 | P | A | -0.7609 | Soluble |
| 165 | V | A | -0.8470 | Soluble |
| 166 | T | A | -0.7870 | Soluble |
| 167 | V | A | -0.5016 | Soluble |
| 168 | S | A | -0.4695 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6521 | Soluble |
| 171 | S | A | -0.6408 | Soluble |
| 172 | G | A | -0.5112 | Soluble |
| 173 | A | A | -0.2348 | Soluble |
| 174 | L | A | 0.0165 | Aggregation-prone |
| 175 | T | A | -0.1722 | Soluble |
| 176 | S | A | -0.1907 | Soluble |
| 177 | G | A | -0.2425 | Soluble |
| 178 | V | A | 0.1462 | Aggregation-prone |
| 179 | H | A | -0.2387 | Soluble |
| 180 | T | A | 0.0222 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.2100 | Soluble |
| 183 | A | A | 0.2787 | Aggregation-prone |
| 184 | V | A | 0.6254 | Aggregation-prone |
| 185 | L | A | 1.1491 | Aggregation-prone |
| 186 | Q | A | 0.2700 | Aggregation-prone |
| 187 | S | A | -0.2190 | Soluble |
| 188 | S | A | -0.2378 | Soluble |
| 189 | G | A | 0.0104 | Aggregation-prone |
| 190 | L | A | 0.0200 | Aggregation-prone |
| 191 | Y | A | 0.4140 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1418 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6182 | Soluble |
| 201 | S | A | -0.5765 | Soluble |
| 202 | S | A | -0.5536 | Soluble |
| 203 | S | A | -0.5986 | Soluble |
| 204 | L | A | -0.7975 | Soluble |
| 205 | G | A | -1.1508 | Soluble |
| 206 | T | A | -0.9079 | Soluble |
| 207 | Q | A | -1.2555 | Soluble |
| 208 | T | A | -1.0286 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -0.9939 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.5046 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.5623 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.9181 | Soluble |
| 217 | P | A | -1.6910 | Soluble |
| 218 | S | A | -1.9578 | Soluble |
| 219 | N | A | -2.6791 | Soluble |
| 220 | T | A | -2.2679 | Soluble |
| 221 | K | A | -2.9000 | Soluble |
| 222 | V | A | -1.7368 | Soluble |
| 223 | D | A | -2.3252 | Soluble |
| 224 | K | A | -1.5813 | Soluble |
| 225 | K | A | -1.8932 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.3821 | Soluble |
| 228 | P | A | -1.2389 | Soluble |
| 1 | D | B | -1.3924 | Soluble |
| 2 | I | B | -0.0090 | Soluble |
| 3 | L | B | 0.6991 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.4988 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.2456 | Soluble |
| 8 | P | B | 0.3269 | Aggregation-prone |
| 9 | A | B | 0.7207 | Aggregation-prone |
| 10 | I | B | 1.8371 | Aggregation-prone |
| 11 | L | B | 0.9684 | Aggregation-prone |
| 12 | S | B | 0.1678 | Aggregation-prone |
| 13 | V | B | -1.2127 | Soluble |
| 14 | S | B | -1.6915 | Soluble |
| 15 | P | B | -2.0293 | Soluble |
| 16 | G | B | -2.3527 | Soluble |
| 17 | E | B | -3.3266 | Soluble |
| 18 | R | B | -3.5049 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | S | B | -0.7844 | Soluble |
| 21 | F | B | 0.0000 | Buried |
| 22 | S | B | -0.9776 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.0454 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.5642 | Soluble |
| 27 | Q | B | -0.7028 | Soluble |
| 28 | F | B | 0.7571 | Aggregation-prone |
| 29 | V | B | 0.0000 | Buried |
| 36 | G | B | -0.0714 | Soluble |
| 37 | S | B | -0.2612 | Soluble |
| 38 | S | B | -0.0472 | Soluble |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | R | B | -1.8035 | Soluble |
| 46 | T | B | -1.6183 | Soluble |
| 47 | N | B | -1.9326 | Soluble |
| 48 | G | B | -1.4839 | Soluble |
| 49 | S | B | -1.0368 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -0.7544 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | K | B | -1.0893 | Soluble |
| 56 | Y | B | -0.4631 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -1.2529 | Soluble |
| 66 | E | B | -2.0657 | Soluble |
| 67 | S | B | -1.2124 | Soluble |
| 68 | M | B | -0.6623 | Soluble |
| 69 | S | B | -0.5394 | Soluble |
| 70 | G | B | -0.4747 | Soluble |
| 71 | I | B | -0.2676 | Soluble |
| 72 | P | B | -0.3273 | Soluble |
| 74 | S | B | -0.6427 | Soluble |
| 75 | R | B | -1.2732 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9938 | Soluble |
| 78 | G | B | -0.7824 | Soluble |
| 79 | S | B | -0.8952 | Soluble |
| 80 | G | B | -1.1166 | Soluble |
| 83 | S | B | -0.7576 | Soluble |
| 84 | G | B | -0.4966 | Soluble |
| 85 | T | B | -1.2028 | Soluble |
| 86 | D | B | -2.4674 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.9007 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | S | B | -1.0127 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | N | B | -2.7637 | Soluble |
| 93 | T | B | -2.5728 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.7450 | Soluble |
| 96 | S | B | -2.2427 | Soluble |
| 97 | E | B | -2.1966 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | I | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | D | B | -0.6067 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | -0.1225 | Soluble |
| 108 | H | B | -0.2708 | Soluble |
| 109 | S | B | -0.1294 | Soluble |
| 114 | W | B | 0.1701 | Aggregation-prone |
| 115 | P | B | -0.3905 | Soluble |
| 116 | F | B | 0.0000 | Buried |
| 117 | T | B | 0.0972 | Aggregation-prone |
| 118 | F | B | 0.1752 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | S | B | -0.7117 | Soluble |
| 121 | G | B | -0.1199 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | N | B | 0.1292 | Aggregation-prone |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -0.4725 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | K | B | -1.3854 | Soluble |
| 128 | R | B | -0.8866 | Soluble |
| 129 | T | B | 0.2507 | Aggregation-prone |
| 130 | V | B | 1.0144 | Aggregation-prone |
| 131 | A | B | 0.2676 | Aggregation-prone |
| 132 | A | B | 0.0449 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1960 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6718 | Soluble |
| 140 | P | B | -0.6905 | Soluble |
| 141 | S | B | -1.3557 | Soluble |
| 142 | D | B | -2.5789 | Soluble |
| 143 | E | B | -2.2529 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.0223 | Soluble |
| 146 | K | B | -2.5863 | Soluble |
| 147 | S | B | -1.5904 | Soluble |
| 148 | G | B | -1.3280 | Soluble |
| 149 | T | B | -1.0198 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.9168 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5453 | Soluble |
| 162 | R | B | -2.7590 | Soluble |
| 163 | E | B | -3.2321 | Soluble |
| 164 | A | B | -2.2903 | Soluble |
| 165 | K | B | -2.1910 | Soluble |
| 166 | V | B | -1.1306 | Soluble |
| 167 | Q | B | -0.8249 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7945 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9258 | Soluble |
| 172 | N | B | -1.6423 | Soluble |
| 173 | A | B | -0.4989 | Soluble |
| 174 | L | B | 0.2599 | Aggregation-prone |
| 175 | Q | B | -0.4966 | Soluble |
| 176 | S | B | -0.7943 | Soluble |
| 177 | G | B | -1.1997 | Soluble |
| 178 | N | B | -1.4618 | Soluble |
| 179 | S | B | -1.3744 | Soluble |
| 180 | Q | B | -1.4026 | Soluble |
| 181 | E | B | -1.5243 | Soluble |
| 182 | S | B | -0.6740 | Soluble |
| 183 | V | B | -0.3571 | Soluble |
| 184 | T | B | -0.8270 | Soluble |
| 185 | E | B | -1.9233 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -1.9051 | Soluble |
| 188 | S | B | -2.2639 | Soluble |
| 189 | K | B | -2.6680 | Soluble |
| 190 | D | B | -2.1193 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7010 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6806 | Soluble |
| 201 | L | B | -0.9903 | Soluble |
| 202 | S | B | -1.2475 | Soluble |
| 203 | K | B | -2.2498 | Soluble |
| 204 | A | B | -2.1260 | Soluble |
| 205 | D | B | -3.2149 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.9021 | Soluble |
| 208 | K | B | -3.9431 | Soluble |
| 209 | H | B | -3.4076 | Soluble |
| 210 | K | B | -3.3783 | Soluble |
| 211 | V | B | -1.5176 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.8547 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1664 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6364 | Soluble |
| 220 | G | B | -0.2535 | Soluble |
| 221 | L | B | -0.1717 | Soluble |
| 222 | S | B | -0.4623 | Soluble |
| 223 | S | B | -0.4226 | Soluble |
| 224 | P | B | -0.5354 | Soluble |
| 225 | V | B | 0.0798 | Aggregation-prone |
| 226 | T | B | -0.3389 | Soluble |
| 227 | K | B | -0.6149 | Soluble |
| 228 | S | B | -0.6337 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -2.0083 | Soluble |
| 231 | R | B | -2.6500 | Soluble |
| 232 | G | B | -2.2077 | Soluble |
| 233 | E | B | -2.5238 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6627 | 3.429 | CSV PDB |
| 4.5 | -0.7119 | 3.4097 | CSV PDB |
| 5.0 | -0.7718 | 3.3862 | CSV PDB |
| 5.5 | -0.8309 | 3.3618 | CSV PDB |
| 6.0 | -0.8761 | 3.3385 | CSV PDB |
| 6.5 | -0.8964 | 3.318 | CSV PDB |
| 7.0 | -0.8902 | 3.3002 | CSV PDB |
| 7.5 | -0.8658 | 3.284 | CSV PDB |
| 8.0 | -0.8316 | 3.2689 | CSV PDB |
| 8.5 | -0.7907 | 3.2551 | CSV PDB |
| 9.0 | -0.7434 | 3.2439 | CSV PDB |