Calculation Parameters
| Chain Sequence(s) |
VQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGKTYYRFKWYSDYAVSVKGRITINPDTSKNQFSLQLNSVTPEDTAVFYCTRESTTYDLLAGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCHHHHHHIVMTQSPDSLAVSLGERATINCKSSQTVLYSSNNKKYLAWYQQKPGQPPNLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPFTFGPGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | A | 0.3291 | Aggregation-prone |
| 3 | Q | A | -1.0753 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | Q | A | -1.5877 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.6830 | Soluble |
| 8 | G | A | -1.0162 | Soluble |
| 9 | P | A | -0.5049 | Soluble |
| 11 | G | A | -0.4634 | Soluble |
| 12 | L | A | -0.1099 | Soluble |
| 13 | V | A | -0.8947 | Soluble |
| 14 | K | A | -2.0617 | Soluble |
| 15 | P | A | -1.7021 | Soluble |
| 16 | S | A | -1.4727 | Soluble |
| 17 | Q | A | -1.9581 | Soluble |
| 18 | T | A | -1.5844 | Soluble |
| 19 | L | A | 0.0000 | Buried |
| 20 | S | A | -0.7800 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | T | A | -0.7197 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -1.1687 | Soluble |
| 25 | I | A | 0.0000 | Buried |
| 26 | S | A | -0.8658 | Soluble |
| 27 | G | A | -0.5747 | Soluble |
| 28 | D | A | -0.7204 | Soluble |
| 29 | S | A | -0.8266 | Soluble |
| 30 | V | A | 0.0000 | Buried |
| 31 | S | A | -0.5432 | Soluble |
| 34 | S | A | -0.8231 | Soluble |
| 35 | N | A | -0.9928 | Soluble |
| 36 | S | A | -0.3542 | Soluble |
| 37 | A | A | 0.0000 | Buried |
| 38 | A | A | 0.0000 | Buried |
| 39 | W | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | I | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.4981 | Soluble |
| 45 | S | A | -0.8577 | Soluble |
| 46 | P | A | -0.7497 | Soluble |
| 47 | S | A | -1.0722 | Soluble |
| 48 | R | A | -1.6648 | Soluble |
| 49 | G | A | -1.0884 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6991 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | K | A | 0.0000 | Buried |
| 56 | T | A | 0.0000 | Buried |
| 57 | Y | A | -0.0145 | Soluble |
| 58 | Y | A | 0.0717 | Aggregation-prone |
| 59 | R | A | -0.3355 | Soluble |
| 60 | F | A | 0.8177 | Aggregation-prone |
| 62 | K | A | -0.5325 | Soluble |
| 63 | W | A | 0.0607 | Aggregation-prone |
| 64 | Y | A | 0.1464 | Aggregation-prone |
| 65 | S | A | -0.3448 | Soluble |
| 66 | D | A | -0.8646 | Soluble |
| 67 | Y | A | -0.4823 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | V | A | 0.8318 | Aggregation-prone |
| 70 | S | A | 0.0278 | Aggregation-prone |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -1.5366 | Soluble |
| 74 | G | A | -1.4175 | Soluble |
| 75 | R | A | -1.5729 | Soluble |
| 76 | I | A | 0.0000 | Buried |
| 77 | T | A | -1.2912 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | N | A | -1.5455 | Soluble |
| 80 | P | A | -1.2965 | Soluble |
| 81 | D | A | -1.8613 | Soluble |
| 82 | T | A | -1.4020 | Soluble |
| 83 | S | A | -1.4396 | Soluble |
| 84 | K | A | -2.2790 | Soluble |
| 85 | N | A | -1.6916 | Soluble |
| 86 | Q | A | -1.6537 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | S | A | -0.9364 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.4393 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | N | A | -1.9028 | Soluble |
| 93 | S | A | -1.5381 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | T | A | -1.3957 | Soluble |
| 96 | P | A | -1.3949 | Soluble |
| 97 | E | A | -1.9374 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.5230 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2816 | Aggregation-prone |
| 102 | F | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | T | A | 0.0000 | Buried |
| 106 | R | A | -0.1177 | Soluble |
| 107 | E | A | 0.0000 | Buried |
| 108 | S | A | -0.0543 | Soluble |
| 109 | T | A | 0.0000 | Buried |
| 110 | T | A | 0.2845 | Aggregation-prone |
| 111 | Y | A | 0.6328 | Aggregation-prone |
| 111A | D | A | -0.7036 | Soluble |
| 112B | L | A | 0.5039 | Aggregation-prone |
| 112A | L | A | 1.5200 | Aggregation-prone |
| 112 | A | A | 0.0000 | Buried |
| 113 | G | A | 0.0000 | Buried |
| 114 | P | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.0342 | Soluble |
| 117 | Y | A | 0.2644 | Aggregation-prone |
| 118 | W | A | -0.3975 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.6363 | Soluble |
| 121 | G | A | -0.8772 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.2419 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.3809 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.9223 | Soluble |
| 128 | S | A | -0.8304 | Soluble |
| 129 | A | A | -0.5498 | Soluble |
| 130 | S | A | -0.6850 | Soluble |
| 131 | T | A | -1.0437 | Soluble |
| 132 | K | A | -1.5762 | Soluble |
| 133 | G | A | -1.4608 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3562 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | 0.0000 | Buried |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.3149 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.1039 | Soluble |
| 143 | S | A | -0.5763 | Soluble |
| 144 | K | A | -0.9353 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.6459 | Soluble |
| 147 | S | A | -0.7003 | Soluble |
| 148 | G | A | -0.8154 | Soluble |
| 149 | G | A | -0.8855 | Soluble |
| 150 | T | A | -0.6116 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5035 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | -0.3264 | Soluble |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.3959 | Soluble |
| 164 | P | A | -0.5177 | Soluble |
| 165 | V | A | -0.5031 | Soluble |
| 166 | T | A | -0.4431 | Soluble |
| 167 | V | A | -0.2880 | Soluble |
| 168 | S | A | -0.3731 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.8845 | Soluble |
| 171 | S | A | -0.7330 | Soluble |
| 172 | G | A | -0.6159 | Soluble |
| 173 | A | A | -0.2978 | Soluble |
| 174 | L | A | -0.0754 | Soluble |
| 175 | T | A | -0.2255 | Soluble |
| 176 | S | A | -0.2462 | Soluble |
| 177 | G | A | -0.3725 | Soluble |
| 178 | V | A | 0.0885 | Aggregation-prone |
| 179 | H | A | -0.3145 | Soluble |
| 180 | T | A | 0.0588 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3053 | Soluble |
| 183 | A | A | 0.1818 | Aggregation-prone |
| 184 | V | A | 0.5364 | Aggregation-prone |
| 185 | L | A | 1.2438 | Aggregation-prone |
| 186 | Q | A | 0.3984 | Aggregation-prone |
| 187 | S | A | -0.0014 | Soluble |
| 188 | S | A | -0.1905 | Soluble |
| 189 | G | A | 0.1142 | Aggregation-prone |
| 190 | L | A | 0.1313 | Aggregation-prone |
| 191 | Y | A | 0.4635 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1589 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6058 | Soluble |
| 201 | S | A | -0.5614 | Soluble |
| 202 | S | A | -0.5732 | Soluble |
| 203 | S | A | -0.5521 | Soluble |
| 204 | L | A | -0.7936 | Soluble |
| 205 | G | A | -0.9658 | Soluble |
| 206 | T | A | -0.7076 | Soluble |
| 207 | Q | A | -1.2518 | Soluble |
| 208 | T | A | -1.0616 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.1259 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4267 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.6400 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.4235 | Soluble |
| 217 | P | A | -1.4220 | Soluble |
| 218 | S | A | -1.7076 | Soluble |
| 219 | N | A | -2.4459 | Soluble |
| 220 | T | A | -1.9880 | Soluble |
| 221 | K | A | -2.5019 | Soluble |
| 222 | V | A | -1.3924 | Soluble |
| 223 | D | A | -2.4916 | Soluble |
| 224 | K | A | -1.9906 | Soluble |
| 225 | K | A | -2.2965 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.7938 | Soluble |
| 228 | P | A | -1.8979 | Soluble |
| 229 | K | A | -2.4189 | Soluble |
| 230 | S | A | -1.1720 | Soluble |
| 231 | C | A | -0.5667 | Soluble |
| 232 | H | A | -1.6410 | Soluble |
| 233 | H | A | -2.1768 | Soluble |
| 234 | H | A | -2.2988 | Soluble |
| 235 | H | A | -2.5709 | Soluble |
| 236 | H | A | -2.2826 | Soluble |
| 237 | H | A | -1.8169 | Soluble |
| 2 | I | B | 0.9484 | Aggregation-prone |
| 3 | V | B | 1.5901 | Aggregation-prone |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -0.4797 | Soluble |
| 6 | Q | B | -1.2649 | Soluble |
| 7 | S | B | -1.4410 | Soluble |
| 8 | P | B | -1.4851 | Soluble |
| 9 | D | B | -2.4360 | Soluble |
| 10 | S | B | -1.7437 | Soluble |
| 11 | L | B | -0.9086 | Soluble |
| 12 | A | B | -0.5304 | Soluble |
| 13 | V | B | -0.6048 | Soluble |
| 14 | S | B | -0.7463 | Soluble |
| 15 | L | B | 0.0014 | Aggregation-prone |
| 16 | G | B | -0.9636 | Soluble |
| 17 | E | B | -2.0235 | Soluble |
| 18 | R | B | -2.4825 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6281 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | N | B | -1.2892 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -1.5528 | Soluble |
| 25 | S | B | 0.0000 | Buried |
| 26 | S | B | -0.3226 | Soluble |
| 27 | Q | B | -1.0211 | Soluble |
| 28 | T | B | -0.6647 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | L | B | -0.3254 | Soluble |
| 31 | Y | B | -0.3507 | Soluble |
| 32 | S | B | -0.7492 | Soluble |
| 33 | S | B | -0.8373 | Soluble |
| 34 | N | B | -1.5710 | Soluble |
| 35 | N | B | -1.8155 | Soluble |
| 36 | K | B | -1.4089 | Soluble |
| 37 | K | B | -0.7907 | Soluble |
| 38 | Y | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | -0.7761 | Soluble |
| 44 | Q | B | -1.1339 | Soluble |
| 45 | K | B | -1.7622 | Soluble |
| 46 | P | B | -1.4322 | Soluble |
| 47 | G | B | -1.4144 | Soluble |
| 48 | Q | B | -2.0362 | Soluble |
| 49 | P | B | -1.2172 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | N | B | -0.9141 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.2042 | Soluble |
| 56 | W | B | -0.4157 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.6413 | Soluble |
| 66 | T | B | -0.5586 | Soluble |
| 67 | R | B | -1.4010 | Soluble |
| 68 | E | B | -1.1521 | Soluble |
| 69 | S | B | -0.9209 | Soluble |
| 70 | G | B | -0.9203 | Soluble |
| 71 | V | B | -0.9941 | Soluble |
| 72 | P | B | -1.2975 | Soluble |
| 74 | D | B | -2.2196 | Soluble |
| 75 | R | B | -1.5716 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9252 | Soluble |
| 78 | G | B | -0.4805 | Soluble |
| 79 | S | B | -0.6493 | Soluble |
| 80 | G | B | -0.8629 | Soluble |
| 83 | S | B | -0.7249 | Soluble |
| 84 | G | B | 0.0000 | Buried |
| 85 | T | B | -1.1427 | Soluble |
| 86 | D | B | -1.6859 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7740 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6341 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.6041 | Soluble |
| 93 | S | B | -1.3225 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.2282 | Soluble |
| 96 | A | B | -1.6409 | Soluble |
| 97 | E | B | -2.2339 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | V | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -1.0911 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | Y | B | 0.0000 | Buried |
| 108 | Y | B | 0.6361 | Aggregation-prone |
| 109 | S | B | 0.1677 | Aggregation-prone |
| 114 | T | B | 0.0496 | Aggregation-prone |
| 115 | P | B | 0.0919 | Aggregation-prone |
| 116 | F | B | 0.0000 | Buried |
| 117 | T | B | 0.3840 | Aggregation-prone |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | P | B | -0.8378 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -2.3370 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.5202 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.0160 | Soluble |
| 128 | R | B | -0.7306 | Soluble |
| 129 | T | B | -0.0642 | Soluble |
| 130 | V | B | 0.3804 | Aggregation-prone |
| 131 | A | B | -0.0254 | Soluble |
| 132 | A | B | -0.0808 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1260 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6095 | Soluble |
| 140 | P | B | -0.8479 | Soluble |
| 141 | S | B | 0.0000 | Buried |
| 142 | D | B | -3.1817 | Soluble |
| 143 | E | B | -3.1210 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3191 | Soluble |
| 146 | K | B | -2.8885 | Soluble |
| 147 | S | B | -1.8128 | Soluble |
| 148 | G | B | -1.2857 | Soluble |
| 149 | T | B | -1.2790 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8963 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.7715 | Soluble |
| 162 | R | B | -3.1062 | Soluble |
| 163 | E | B | -3.2082 | Soluble |
| 164 | A | B | -2.2526 | Soluble |
| 165 | K | B | -2.1156 | Soluble |
| 166 | V | B | -0.8939 | Soluble |
| 167 | Q | B | -0.5078 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7272 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9242 | Soluble |
| 172 | N | B | -1.6055 | Soluble |
| 173 | A | B | -0.4796 | Soluble |
| 174 | L | B | 0.3135 | Aggregation-prone |
| 175 | Q | B | -0.5785 | Soluble |
| 176 | S | B | -0.7530 | Soluble |
| 177 | G | B | -1.2712 | Soluble |
| 178 | N | B | -1.5877 | Soluble |
| 179 | S | B | -1.5059 | Soluble |
| 180 | Q | B | -1.4737 | Soluble |
| 181 | E | B | -1.7612 | Soluble |
| 182 | S | B | -0.9707 | Soluble |
| 183 | V | B | -0.9203 | Soluble |
| 184 | T | B | 0.0000 | Buried |
| 185 | E | B | -2.2668 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.0429 | Soluble |
| 188 | S | B | -2.2797 | Soluble |
| 189 | K | B | -2.5665 | Soluble |
| 190 | D | B | -1.8541 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.8036 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6997 | Soluble |
| 201 | L | B | -0.9808 | Soluble |
| 202 | S | B | -1.2120 | Soluble |
| 203 | K | B | -2.2848 | Soluble |
| 204 | A | B | -2.0782 | Soluble |
| 205 | D | B | -2.8397 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.6608 | Soluble |
| 208 | K | B | -3.7067 | Soluble |
| 209 | H | B | -2.9259 | Soluble |
| 210 | K | B | -2.6753 | Soluble |
| 211 | V | B | -1.2903 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | 0.0000 | Buried |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0245 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5682 | Soluble |
| 220 | G | B | -0.4107 | Soluble |
| 221 | L | B | -0.1922 | Soluble |
| 222 | S | B | -0.4342 | Soluble |
| 223 | S | B | -0.3859 | Soluble |
| 224 | P | B | -0.4041 | Soluble |
| 225 | V | B | 0.3133 | Aggregation-prone |
| 226 | T | B | -0.1552 | Soluble |
| 227 | K | B | -0.4807 | Soluble |
| 228 | S | B | -0.5249 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.3466 | Soluble |
| 231 | R | B | -1.9729 | Soluble |
| 232 | G | B | -1.7912 | Soluble |
| 233 | E | B | -1.5844 | Soluble |
| 234 | C | B | -0.5100 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7528 | 2.3714 | CSV PDB |
| 4.5 | -0.7942 | 2.3022 | CSV PDB |
| 5.0 | -0.841 | 2.21 | CSV PDB |
| 5.5 | -0.8821 | 2.1067 | CSV PDB |
| 6.0 | -0.9054 | 1.9992 | CSV PDB |
| 6.5 | -0.903 | 2.051 | CSV PDB |
| 7.0 | -0.8777 | 2.23 | CSV PDB |
| 7.5 | -0.8405 | 2.4501 | CSV PDB |
| 8.0 | -0.7982 | 2.6877 | CSV PDB |
| 8.5 | -0.7517 | 2.9311 | CSV PDB |
| 9.0 | -0.6999 | 3.1751 | CSV PDB |