Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGSSVKVSCKASGYTFSSNVISWVRQAPGQGLEWMGGVIPIVDIANYAQRFKGRVTITADESTSTTYMELSSLRSEDTAVYYCASTLGLVLDAMDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVEPETVLTQSPGTLSLSPGERATLSCRASQSLGSSYLAWYQQKPGQAPRLLIYGASSRAPGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYADSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.2319 | Soluble |
| 2 | V | B | -0.3074 | Soluble |
| 3 | Q | B | -0.7084 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.2734 | Aggregation-prone |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.5060 | Soluble |
| 8 | G | B | -0.4973 | Soluble |
| 9 | A | B | -0.0031 | Soluble |
| 11 | E | B | -0.2855 | Soluble |
| 12 | V | B | 0.1903 | Aggregation-prone |
| 13 | K | B | -1.3445 | Soluble |
| 14 | K | B | -2.4092 | Soluble |
| 15 | P | B | -2.1267 | Soluble |
| 16 | G | B | -1.7349 | Soluble |
| 17 | S | B | -1.3315 | Soluble |
| 18 | S | B | -1.4498 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | K | B | -2.2058 | Soluble |
| 21 | V | B | 0.0000 | Buried |
| 22 | S | B | -0.5599 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -0.7126 | Soluble |
| 25 | A | B | -0.6066 | Soluble |
| 26 | S | B | -0.4469 | Soluble |
| 27 | G | B | -0.5116 | Soluble |
| 28 | Y | B | 0.3870 | Aggregation-prone |
| 29 | T | B | 0.7718 | Aggregation-prone |
| 30 | F | B | 1.6298 | Aggregation-prone |
| 35 | S | B | 0.4095 | Aggregation-prone |
| 36 | S | B | 0.3105 | Aggregation-prone |
| 37 | N | B | 0.0699 | Aggregation-prone |
| 38 | V | B | 0.0000 | Buried |
| 39 | I | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.5256 | Soluble |
| 45 | A | B | -0.8370 | Soluble |
| 46 | P | B | -0.7460 | Soluble |
| 47 | G | B | -1.2257 | Soluble |
| 48 | Q | B | -1.8524 | Soluble |
| 49 | G | B | -1.2780 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.6081 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | M | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | G | B | 0.0000 | Buried |
| 56 | V | B | 0.0000 | Buried |
| 57 | I | B | 1.1266 | Aggregation-prone |
| 58 | P | B | 0.4647 | Aggregation-prone |
| 59 | I | B | 1.9720 | Aggregation-prone |
| 62 | V | B | 2.3389 | Aggregation-prone |
| 63 | D | B | 0.5446 | Aggregation-prone |
| 64 | I | B | 2.0159 | Aggregation-prone |
| 65 | A | B | 0.5130 | Aggregation-prone |
| 66 | N | B | -0.6822 | Soluble |
| 67 | Y | B | -1.4518 | Soluble |
| 68 | A | B | 0.0000 | Buried |
| 69 | Q | B | -3.1207 | Soluble |
| 70 | R | B | -3.0099 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | K | B | -3.1243 | Soluble |
| 74 | G | B | -1.9515 | Soluble |
| 75 | R | B | -1.7989 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -1.1555 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | T | B | -0.4379 | Soluble |
| 80 | A | B | -0.3676 | Soluble |
| 81 | D | B | -1.6626 | Soluble |
| 82 | E | B | -1.6776 | Soluble |
| 83 | S | B | -1.0730 | Soluble |
| 84 | T | B | -1.0893 | Soluble |
| 85 | S | B | -1.1029 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | T | B | 0.0000 | Buried |
| 88 | Y | B | -0.6427 | Soluble |
| 89 | M | B | 0.0000 | Buried |
| 90 | E | B | -1.8567 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | S | B | -1.2955 | Soluble |
| 93 | S | B | -1.2597 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.9624 | Soluble |
| 96 | S | B | -2.0776 | Soluble |
| 97 | E | B | -1.9859 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.6067 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.3647 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | S | B | 0.0000 | Buried |
| 107 | T | B | 0.0000 | Buried |
| 108 | L | B | 0.8164 | Aggregation-prone |
| 109 | G | B | 0.5852 | Aggregation-prone |
| 110 | L | B | 1.6551 | Aggregation-prone |
| 111 | V | B | 0.9864 | Aggregation-prone |
| 112 | L | B | 0.6152 | Aggregation-prone |
| 113 | D | B | 0.0000 | Buried |
| 114 | A | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | -0.1368 | Soluble |
| 117 | Y | B | 0.4329 | Aggregation-prone |
| 118 | W | B | -0.0612 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.1640 | Soluble |
| 121 | G | B | -0.5141 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.4783 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | 0.0000 | Buried |
| 128 | S | B | -0.9074 | Soluble |
| 129 | A | B | -0.5984 | Soluble |
| 130 | S | B | -0.3776 | Soluble |
| 131 | T | B | -0.6718 | Soluble |
| 132 | K | B | -1.1679 | Soluble |
| 133 | G | B | -1.3128 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4284 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.3512 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.5677 | Soluble |
| 141 | P | B | -0.4187 | Soluble |
| 142 | C | B | -0.4910 | Soluble |
| 143 | S | B | -0.7443 | Soluble |
| 144 | R | B | -1.1602 | Soluble |
| 145 | S | B | -0.9162 | Soluble |
| 146 | T | B | -0.6568 | Soluble |
| 147 | S | B | -0.6691 | Soluble |
| 148 | E | B | -0.8742 | Soluble |
| 149 | S | B | -0.6897 | Soluble |
| 150 | T | B | -0.5238 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.5321 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | -0.6387 | Soluble |
| 163 | E | B | -0.8046 | Soluble |
| 164 | P | B | -0.8088 | Soluble |
| 165 | V | B | -0.6736 | Soluble |
| 166 | T | B | -0.4992 | Soluble |
| 167 | V | B | -0.2784 | Soluble |
| 168 | S | B | -0.4104 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -1.1200 | Soluble |
| 171 | S | B | -0.8178 | Soluble |
| 172 | G | B | -0.5967 | Soluble |
| 173 | A | B | -0.2926 | Soluble |
| 174 | L | B | -0.1052 | Soluble |
| 175 | T | B | -0.2061 | Soluble |
| 176 | S | B | -0.2071 | Soluble |
| 177 | G | B | -0.2705 | Soluble |
| 178 | V | B | 0.1018 | Aggregation-prone |
| 179 | H | B | -0.3624 | Soluble |
| 180 | T | B | 0.0125 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.4612 | Soluble |
| 183 | A | B | -0.0461 | Soluble |
| 184 | V | B | 0.1523 | Aggregation-prone |
| 185 | L | B | 0.4261 | Aggregation-prone |
| 186 | Q | B | -0.0204 | Soluble |
| 187 | S | B | -0.2226 | Soluble |
| 188 | S | B | -0.3287 | Soluble |
| 189 | G | B | -0.3402 | Soluble |
| 190 | L | B | -0.1534 | Soluble |
| 191 | Y | B | 0.0000 | Buried |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1651 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.4060 | Soluble |
| 201 | S | B | -0.5857 | Soluble |
| 202 | S | B | -0.6025 | Soluble |
| 203 | S | B | 0.0000 | Buried |
| 204 | L | B | -0.8947 | Soluble |
| 205 | G | B | -1.2776 | Soluble |
| 206 | T | B | -1.1249 | Soluble |
| 207 | K | B | -1.8807 | Soluble |
| 208 | T | B | -1.6715 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | T | B | 0.0000 | Buried |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | 0.0000 | Buried |
| 213 | V | B | 0.0000 | Buried |
| 214 | D | B | -1.7067 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.7333 | Soluble |
| 217 | P | B | -1.6946 | Soluble |
| 218 | S | B | -1.8331 | Soluble |
| 219 | N | B | -2.5535 | Soluble |
| 220 | T | B | -1.9986 | Soluble |
| 221 | K | B | -2.5032 | Soluble |
| 222 | V | B | -1.3762 | Soluble |
| 223 | D | B | -2.6819 | Soluble |
| 224 | K | B | -2.3923 | Soluble |
| 225 | R | B | -3.0171 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.4927 | Soluble |
| 228 | P | B | -1.0699 | Soluble |
| 1 | E | A | -1.9792 | Soluble |
| 2 | T | A | 0.0000 | Buried |
| 3 | V | A | 0.6176 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.7867 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.9264 | Soluble |
| 8 | P | A | -0.5259 | Soluble |
| 9 | G | A | -0.8737 | Soluble |
| 10 | T | A | -0.4913 | Soluble |
| 11 | L | A | -0.1745 | Soluble |
| 12 | S | A | -0.4527 | Soluble |
| 13 | L | A | -0.7070 | Soluble |
| 14 | S | A | -1.2625 | Soluble |
| 15 | P | A | -1.7674 | Soluble |
| 16 | G | A | -2.0781 | Soluble |
| 17 | E | A | -2.4960 | Soluble |
| 18 | R | A | -3.0718 | Soluble |
| 19 | A | A | 0.0000 | Buried |
| 20 | T | A | -0.5504 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.9296 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.3156 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0425 | Soluble |
| 27 | Q | A | -1.7284 | Soluble |
| 28 | S | A | -1.2777 | Soluble |
| 29 | L | A | 0.0000 | Buried |
| 30 | G | A | -0.5652 | Soluble |
| 36 | S | A | -0.5087 | Soluble |
| 37 | S | A | 0.1146 | Aggregation-prone |
| 38 | Y | A | 0.5593 | Aggregation-prone |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.3964 | Soluble |
| 46 | P | A | -1.4394 | Soluble |
| 47 | G | A | -1.4313 | Soluble |
| 48 | Q | A | -2.0447 | Soluble |
| 49 | A | A | -1.1962 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -1.0869 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.2938 | Aggregation-prone |
| 56 | G | A | 0.0849 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -0.4749 | Soluble |
| 66 | S | A | -0.5452 | Soluble |
| 67 | R | A | -1.3103 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | P | A | -0.7642 | Soluble |
| 70 | G | A | -0.9578 | Soluble |
| 71 | I | A | 0.0000 | Buried |
| 72 | P | A | -1.3502 | Soluble |
| 74 | D | A | -2.2244 | Soluble |
| 75 | R | A | -2.1738 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.9170 | Soluble |
| 78 | G | A | 0.0000 | Buried |
| 79 | S | A | -0.6776 | Soluble |
| 80 | G | A | -1.0740 | Soluble |
| 83 | S | A | -0.9844 | Soluble |
| 84 | G | A | -1.1431 | Soluble |
| 85 | T | A | -1.7533 | Soluble |
| 86 | D | A | -2.1207 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7490 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.8329 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -2.3882 | Soluble |
| 93 | R | A | -3.2378 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | E | A | -2.5193 | Soluble |
| 96 | P | A | -1.5755 | Soluble |
| 97 | E | A | -2.2655 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.5699 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | -0.1591 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | Y | A | 0.0000 | Buried |
| 108 | A | A | -0.7408 | Soluble |
| 109 | D | A | -1.9614 | Soluble |
| 114 | S | A | -1.5681 | Soluble |
| 115 | P | A | 0.0000 | Buried |
| 116 | I | A | 0.0000 | Buried |
| 117 | T | A | -0.3208 | Soluble |
| 118 | F | A | 0.0978 | Aggregation-prone |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3753 | Soluble |
| 121 | G | A | -0.9761 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | R | A | -0.6029 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | -0.5336 | Soluble |
| 127 | K | A | -1.1317 | Soluble |
| 128 | R | A | -0.9806 | Soluble |
| 129 | T | A | -0.0668 | Soluble |
| 130 | V | A | 0.5985 | Aggregation-prone |
| 131 | A | A | 0.1293 | Aggregation-prone |
| 132 | A | A | -0.0732 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1910 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.2455 | Soluble |
| 140 | P | A | 0.0000 | Buried |
| 141 | S | A | -1.6834 | Soluble |
| 142 | D | A | -3.0361 | Soluble |
| 143 | E | A | -3.2652 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.3535 | Soluble |
| 146 | K | A | -2.9173 | Soluble |
| 147 | S | A | -1.7856 | Soluble |
| 148 | G | A | -1.3940 | Soluble |
| 149 | T | A | -1.0634 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8209 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.1274 | Soluble |
| 162 | R | A | -1.8812 | Soluble |
| 163 | E | A | -2.6770 | Soluble |
| 164 | A | A | -2.0930 | Soluble |
| 165 | K | A | -2.2977 | Soluble |
| 166 | V | A | 0.0000 | Buried |
| 167 | Q | A | -0.7450 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6247 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.6960 | Soluble |
| 172 | N | A | -1.4708 | Soluble |
| 173 | A | A | -0.3846 | Soluble |
| 174 | L | A | 0.3764 | Aggregation-prone |
| 175 | Q | A | -0.4449 | Soluble |
| 176 | S | A | -0.7659 | Soluble |
| 177 | G | A | -1.2905 | Soluble |
| 178 | N | A | -1.6526 | Soluble |
| 179 | S | A | -1.4835 | Soluble |
| 180 | Q | A | -1.4057 | Soluble |
| 181 | E | A | -1.8539 | Soluble |
| 182 | S | A | -1.0265 | Soluble |
| 183 | V | A | -0.7142 | Soluble |
| 184 | T | A | -1.0740 | Soluble |
| 185 | E | A | -2.1589 | Soluble |
| 186 | Q | A | -1.7204 | Soluble |
| 187 | D | A | -2.0231 | Soluble |
| 188 | S | A | -1.7557 | Soluble |
| 189 | K | A | -2.2711 | Soluble |
| 190 | D | A | -1.7542 | Soluble |
| 191 | S | A | -1.6995 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | 0.0000 | Buried |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.6774 | Soluble |
| 201 | L | A | -0.9213 | Soluble |
| 202 | S | A | -1.1370 | Soluble |
| 203 | K | A | -2.0843 | Soluble |
| 204 | A | A | -1.9553 | Soluble |
| 205 | D | A | -2.9045 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.2764 | Soluble |
| 208 | K | A | -3.5040 | Soluble |
| 209 | H | A | -2.6339 | Soluble |
| 210 | K | A | -2.3606 | Soluble |
| 211 | V | A | -0.7887 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | -0.6187 | Soluble |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.5925 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.2147 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.4203 | Soluble |
| 220 | G | A | -0.3483 | Soluble |
| 221 | L | A | -0.1666 | Soluble |
| 222 | S | A | -0.4290 | Soluble |
| 223 | S | A | -0.3827 | Soluble |
| 224 | P | A | -0.4510 | Soluble |
| 225 | V | A | 0.2508 | Aggregation-prone |
| 226 | T | A | -0.2522 | Soluble |
| 227 | K | A | -0.3813 | Soluble |
| 228 | S | A | -0.4080 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.3251 | Soluble |
| 231 | R | A | -1.8558 | Soluble |
| 232 | G | A | -1.7775 | Soluble |
| 233 | E | A | -2.1198 | Soluble |
| 234 | C | A | -0.9241 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6004 | 3.952 | CSV PDB |
| 4.5 | -0.6476 | 3.7854 | CSV PDB |
| 5.0 | -0.7044 | 3.6388 | CSV PDB |
| 5.5 | -0.7607 | 3.6388 | CSV PDB |
| 6.0 | -0.8056 | 3.6388 | CSV PDB |
| 6.5 | -0.8304 | 3.6388 | CSV PDB |
| 7.0 | -0.8331 | 3.6388 | CSV PDB |
| 7.5 | -0.8198 | 3.6388 | CSV PDB |
| 8.0 | -0.7974 | 3.6388 | CSV PDB |
| 8.5 | -0.7684 | 3.6388 | CSV PDB |
| 9.0 | -0.7329 | 3.6387 | CSV PDB |