Calculation Parameters
| Chain Sequence(s) |
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVMWYDGSNKDYVDSVKGRFTISRDNSKNTLYLQMNRLRAEDTAVYYCAREKDHYDILTGYNYYYGLDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKRLIYAASSLESGVPSRFSGSGSGTEFTLTISSVQPEDFVTYYCLQHNSNPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -0.9861 | Soluble |
| 2 | V | B | 0.0297 | Aggregation-prone |
| 3 | Q | B | -0.4441 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.4620 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.6453 | Soluble |
| 8 | G | B | -1.0598 | Soluble |
| 9 | G | B | -0.6202 | Soluble |
| 11 | G | B | 0.1713 | Aggregation-prone |
| 12 | V | B | 0.7754 | Aggregation-prone |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.6818 | Soluble |
| 15 | P | B | -2.2104 | Soluble |
| 16 | G | B | -2.7978 | Soluble |
| 17 | R | B | -3.2101 | Soluble |
| 18 | S | B | -2.5205 | Soluble |
| 19 | L | B | -1.7526 | Soluble |
| 20 | R | B | -2.2795 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.5715 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.2542 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.4291 | Soluble |
| 27 | G | B | -0.5374 | Soluble |
| 28 | F | B | -0.1599 | Soluble |
| 29 | T | B | -0.2240 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -0.5800 | Soluble |
| 36 | S | B | -0.3709 | Soluble |
| 37 | Y | B | -0.3492 | Soluble |
| 38 | G | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -1.0112 | Soluble |
| 45 | A | B | -1.2457 | Soluble |
| 46 | P | B | -0.9859 | Soluble |
| 47 | G | B | -1.4816 | Soluble |
| 48 | K | B | -2.2608 | Soluble |
| 49 | G | B | -1.4056 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.9280 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | V | B | 0.0000 | Buried |
| 56 | M | B | 0.0000 | Buried |
| 57 | W | B | 0.0000 | Buried |
| 58 | Y | B | -0.7078 | Soluble |
| 59 | D | B | -2.0126 | Soluble |
| 62 | G | B | -1.7305 | Soluble |
| 63 | S | B | -1.7003 | Soluble |
| 64 | N | B | -2.1581 | Soluble |
| 65 | K | B | -1.7650 | Soluble |
| 66 | D | B | -1.5855 | Soluble |
| 67 | Y | B | -1.2886 | Soluble |
| 68 | V | B | -1.3928 | Soluble |
| 69 | D | B | -2.3711 | Soluble |
| 70 | S | B | -1.6399 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.4988 | Soluble |
| 74 | G | B | -1.7789 | Soluble |
| 75 | R | B | 0.0000 | Buried |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -1.0783 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.6162 | Soluble |
| 80 | R | B | -0.9730 | Soluble |
| 81 | D | B | -1.7499 | Soluble |
| 82 | N | B | -2.0263 | Soluble |
| 83 | S | B | -1.8122 | Soluble |
| 84 | K | B | -2.5249 | Soluble |
| 85 | N | B | -1.9541 | Soluble |
| 86 | T | B | -1.1352 | Soluble |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | -0.7121 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.6163 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.5420 | Soluble |
| 93 | R | B | -3.2364 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.2528 | Soluble |
| 96 | A | B | -1.2423 | Soluble |
| 97 | E | B | -1.8846 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.5444 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.0193 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | -0.3808 | Soluble |
| 107 | E | B | 0.0000 | Buried |
| 108 | K | B | -0.9178 | Soluble |
| 109 | D | B | -0.2927 | Soluble |
| 110 | H | B | 0.0044 | Aggregation-prone |
| 111 | Y | B | 1.5260 | Aggregation-prone |
| 111A | D | B | 1.6100 | Aggregation-prone |
| 111B | I | B | 2.8330 | Aggregation-prone |
| 111C | L | B | 2.6559 | Aggregation-prone |
| 111D | T | B | 1.5971 | Aggregation-prone |
| 112D | G | B | 1.5463 | Aggregation-prone |
| 112C | Y | B | 1.6577 | Aggregation-prone |
| 112B | N | B | 0.6470 | Aggregation-prone |
| 112A | Y | B | 0.6406 | Aggregation-prone |
| 112 | Y | B | 0.6897 | Aggregation-prone |
| 113 | Y | B | 0.7525 | Aggregation-prone |
| 114 | G | B | 0.0000 | Buried |
| 115 | L | B | 0.0000 | Buried |
| 116 | D | B | -0.6498 | Soluble |
| 117 | V | B | -0.2324 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.4855 | Soluble |
| 121 | G | B | -0.7949 | Soluble |
| 122 | T | B | -0.3580 | Soluble |
| 123 | T | B | -0.0516 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.1111 | Soluble |
| 126 | V | B | -0.6503 | Soluble |
| 127 | S | B | -0.3107 | Soluble |
| 128 | S | B | -0.4178 | Soluble |
| 129 | A | B | -0.2858 | Soluble |
| 130 | S | B | -0.3576 | Soluble |
| 131 | T | B | -0.5296 | Soluble |
| 132 | K | B | -1.1236 | Soluble |
| 133 | G | B | -1.3160 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.2310 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.0598 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.8346 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.0790 | Soluble |
| 143 | S | B | -1.5385 | Soluble |
| 144 | K | B | -2.0332 | Soluble |
| 145 | S | B | -1.4001 | Soluble |
| 146 | T | B | -0.9120 | Soluble |
| 147 | S | B | -0.7892 | Soluble |
| 148 | G | B | -1.1286 | Soluble |
| 149 | G | B | -0.8475 | Soluble |
| 150 | T | B | -0.4920 | Soluble |
| 151 | A | B | -0.2811 | Soluble |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.2608 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | -0.6948 | Soluble |
| 163 | E | B | -0.9517 | Soluble |
| 164 | P | B | -1.0007 | Soluble |
| 165 | V | B | -0.8633 | Soluble |
| 166 | T | B | -0.6976 | Soluble |
| 167 | V | B | -0.2338 | Soluble |
| 168 | S | B | -0.3753 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.6990 | Soluble |
| 171 | S | B | -0.5947 | Soluble |
| 172 | G | B | -0.3464 | Soluble |
| 173 | A | B | -0.1666 | Soluble |
| 174 | L | B | 0.0470 | Aggregation-prone |
| 175 | T | B | -0.1410 | Soluble |
| 176 | S | B | -0.1936 | Soluble |
| 177 | G | B | -0.2626 | Soluble |
| 178 | V | B | 0.1283 | Aggregation-prone |
| 179 | H | B | -0.3073 | Soluble |
| 180 | T | B | 0.0329 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.4756 | Soluble |
| 183 | A | B | 0.1567 | Aggregation-prone |
| 184 | V | B | 0.4708 | Aggregation-prone |
| 185 | L | B | 1.3612 | Aggregation-prone |
| 186 | Q | B | 0.3870 | Aggregation-prone |
| 187 | S | B | -0.0788 | Soluble |
| 188 | S | B | -0.1206 | Soluble |
| 189 | G | B | 0.1198 | Aggregation-prone |
| 190 | L | B | 0.1970 | Aggregation-prone |
| 191 | Y | B | 0.4292 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1252 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.4989 | Soluble |
| 201 | S | B | -0.8546 | Soluble |
| 202 | S | B | -0.7043 | Soluble |
| 203 | S | B | -0.6504 | Soluble |
| 204 | L | B | -0.8112 | Soluble |
| 205 | G | B | -1.0138 | Soluble |
| 206 | T | B | -0.7282 | Soluble |
| 207 | Q | B | -1.2273 | Soluble |
| 208 | T | B | -1.1863 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.3073 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4767 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.1033 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8431 | Soluble |
| 217 | P | B | -1.6968 | Soluble |
| 218 | S | B | -1.8437 | Soluble |
| 219 | N | B | -2.6128 | Soluble |
| 220 | T | B | -2.1097 | Soluble |
| 221 | K | B | -2.7504 | Soluble |
| 222 | V | B | -1.5306 | Soluble |
| 223 | D | B | -2.5949 | Soluble |
| 224 | K | B | -2.0919 | Soluble |
| 225 | K | B | -2.6425 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.5248 | Soluble |
| 228 | P | B | -1.4687 | Soluble |
| 229 | K | B | -0.9750 | Soluble |
| 230 | S | B | -0.3469 | Soluble |
| 231 | C | B | 0.1136 | Aggregation-prone |
| 1 | D | A | -2.5397 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.2287 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.4312 | Soluble |
| 6 | Q | A | -1.0254 | Soluble |
| 7 | S | A | -0.6962 | Soluble |
| 8 | P | A | -0.6222 | Soluble |
| 9 | S | A | -0.8605 | Soluble |
| 10 | S | A | -0.8367 | Soluble |
| 11 | L | A | -0.4554 | Soluble |
| 12 | S | A | -0.6512 | Soluble |
| 13 | A | A | 0.0000 | Buried |
| 14 | S | A | -0.5076 | Soluble |
| 15 | V | A | 0.0763 | Aggregation-prone |
| 16 | G | A | -0.8813 | Soluble |
| 17 | D | A | -1.7809 | Soluble |
| 18 | R | A | -2.3733 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6330 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.9239 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.9726 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -2.1834 | Soluble |
| 27 | Q | A | -2.7202 | Soluble |
| 28 | G | A | -2.3055 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | R | A | -2.9162 | Soluble |
| 37 | N | A | -1.9715 | Soluble |
| 38 | D | A | -0.8968 | Soluble |
| 39 | L | A | 0.0000 | Buried |
| 40 | G | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -1.5678 | Soluble |
| 45 | K | A | -1.8835 | Soluble |
| 46 | P | A | -1.5214 | Soluble |
| 47 | G | A | -1.7450 | Soluble |
| 48 | K | A | -2.7249 | Soluble |
| 49 | A | A | -1.8175 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.9378 | Soluble |
| 52 | R | A | -0.8548 | Soluble |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.3870 | Aggregation-prone |
| 56 | A | A | -0.1709 | Soluble |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -0.3573 | Soluble |
| 66 | S | A | 0.0936 | Aggregation-prone |
| 67 | L | A | 0.2143 | Aggregation-prone |
| 68 | E | A | -0.4367 | Soluble |
| 69 | S | A | -0.4302 | Soluble |
| 70 | G | A | -0.5127 | Soluble |
| 71 | V | A | -0.2288 | Soluble |
| 72 | P | A | -0.3335 | Soluble |
| 74 | S | A | -0.4481 | Soluble |
| 75 | R | A | -0.7381 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.2843 | Soluble |
| 78 | G | A | 0.0000 | Buried |
| 79 | S | A | -0.8380 | Soluble |
| 80 | G | A | -1.6228 | Soluble |
| 83 | S | A | -1.8521 | Soluble |
| 84 | G | A | -2.3775 | Soluble |
| 85 | T | A | -2.4112 | Soluble |
| 86 | E | A | -2.8686 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.8779 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6151 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.4579 | Soluble |
| 93 | S | A | -1.2459 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | Q | A | -0.8112 | Soluble |
| 96 | P | A | -0.9176 | Soluble |
| 97 | E | A | -1.8859 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.5193 | Soluble |
| 100 | V | A | -0.8117 | Soluble |
| 101 | T | A | 0.0000 | Buried |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | L | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | H | A | -0.4248 | Soluble |
| 108 | N | A | -1.3066 | Soluble |
| 109 | S | A | -1.4022 | Soluble |
| 114 | N | A | -1.8117 | Soluble |
| 115 | P | A | -1.6571 | Soluble |
| 116 | L | A | 0.0000 | Buried |
| 117 | T | A | -0.9456 | Soluble |
| 118 | F | A | -0.3402 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | G | A | -1.0927 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.6707 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | -0.2563 | Soluble |
| 127 | K | A | -0.9307 | Soluble |
| 128 | R | A | -0.9436 | Soluble |
| 129 | T | A | -0.0592 | Soluble |
| 130 | V | A | 0.6747 | Aggregation-prone |
| 131 | A | A | 0.1581 | Aggregation-prone |
| 132 | A | A | -0.0948 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1372 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0801 | Aggregation-prone |
| 137 | I | A | 0.0601 | Aggregation-prone |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | 0.0000 | Buried |
| 140 | P | A | 0.0000 | Buried |
| 141 | S | A | -1.4663 | Soluble |
| 142 | D | A | -2.6301 | Soluble |
| 143 | E | A | -2.2313 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -1.9987 | Soluble |
| 146 | K | A | -2.5611 | Soluble |
| 147 | S | A | -1.5709 | Soluble |
| 148 | G | A | -1.1379 | Soluble |
| 149 | T | A | -0.8993 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | -0.3535 | Soluble |
| 158 | N | A | -0.7616 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.1544 | Soluble |
| 162 | R | A | -1.8367 | Soluble |
| 163 | E | A | -2.6140 | Soluble |
| 164 | A | A | -1.8697 | Soluble |
| 165 | K | A | -1.9136 | Soluble |
| 166 | V | A | -0.9081 | Soluble |
| 167 | Q | A | -0.5667 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.7433 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -2.1953 | Soluble |
| 172 | N | A | -1.5829 | Soluble |
| 173 | A | A | -0.4953 | Soluble |
| 174 | L | A | 0.5910 | Aggregation-prone |
| 175 | Q | A | -0.3097 | Soluble |
| 176 | S | A | -0.6185 | Soluble |
| 177 | G | A | -1.1822 | Soluble |
| 178 | N | A | -1.3932 | Soluble |
| 179 | S | A | -1.4557 | Soluble |
| 180 | Q | A | -1.5405 | Soluble |
| 181 | E | A | -1.9133 | Soluble |
| 182 | S | A | -0.9006 | Soluble |
| 183 | V | A | -0.3694 | Soluble |
| 184 | T | A | -0.8865 | Soluble |
| 185 | E | A | -2.0401 | Soluble |
| 186 | Q | A | -1.6600 | Soluble |
| 187 | D | A | -1.8860 | Soluble |
| 188 | S | A | -1.6857 | Soluble |
| 189 | K | A | -2.2413 | Soluble |
| 190 | D | A | -1.7815 | Soluble |
| 191 | S | A | -1.6638 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.7785 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.5506 | Soluble |
| 201 | L | A | -0.4893 | Soluble |
| 202 | S | A | -1.0130 | Soluble |
| 203 | K | A | -2.2493 | Soluble |
| 204 | A | A | -1.9613 | Soluble |
| 205 | D | A | -2.3734 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.8163 | Soluble |
| 208 | K | A | -3.6207 | Soluble |
| 209 | H | A | -3.3137 | Soluble |
| 210 | K | A | -3.4302 | Soluble |
| 211 | V | A | -2.0478 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | -0.8852 | Soluble |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.7165 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1090 | Soluble |
| 218 | H | A | -1.3095 | Soluble |
| 219 | Q | A | -1.5902 | Soluble |
| 220 | G | A | -0.3344 | Soluble |
| 221 | L | A | -0.2466 | Soluble |
| 222 | S | A | -0.4920 | Soluble |
| 223 | S | A | -0.4135 | Soluble |
| 224 | P | A | -0.4675 | Soluble |
| 225 | V | A | -0.1018 | Soluble |
| 226 | T | A | -0.6346 | Soluble |
| 227 | K | A | -1.0553 | Soluble |
| 228 | S | A | -0.7027 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.8263 | Soluble |
| 231 | R | A | -2.7848 | Soluble |
| 232 | G | A | -1.6255 | Soluble |
| 233 | E | A | -1.4128 | Soluble |
| 234 | C | A | -0.5931 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.8088 | 4.0581 | CSV PDB |
| 4.5 | -0.8492 | 4.0058 | CSV PDB |
| 5.0 | -0.8954 | 3.9534 | CSV PDB |
| 5.5 | -0.9379 | 3.9066 | CSV PDB |
| 6.0 | -0.965 | 3.8693 | CSV PDB |
| 6.5 | -0.9682 | 3.8371 | CSV PDB |
| 7.0 | -0.9487 | 3.8 | CSV PDB |
| 7.5 | -0.9146 | 3.7552 | CSV PDB |
| 8.0 | -0.8721 | 3.7096 | CSV PDB |
| 8.5 | -0.8232 | 3.673 | CSV PDB |
| 9.0 | -0.7686 | 3.6508 | CSV PDB |