Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFTSTGISWVRQAPGKGLEWVGRTHLGDGSTNYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARTYGIYDLYVDYTEYVMDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQDVDTSLAWYKQKPGKAPKLLIYSASFLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSTGHPQTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | E (Heavy), D (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | E | -1.8973 | Soluble |
| 2 | V | E | -0.8643 | Soluble |
| 3 | Q | E | -0.7540 | Soluble |
| 4 | L | E | 0.0000 | Buried |
| 5 | V | E | 1.1475 | Aggregation-prone |
| 6 | E | E | 0.2431 | Aggregation-prone |
| 7 | S | E | -0.3861 | Soluble |
| 8 | G | E | -0.8000 | Soluble |
| 9 | G | E | -0.4144 | Soluble |
| 11 | G | E | -0.0808 | Soluble |
| 12 | L | E | 0.0351 | Aggregation-prone |
| 13 | V | E | -0.6106 | Soluble |
| 14 | Q | E | -1.5898 | Soluble |
| 15 | P | E | -1.8537 | Soluble |
| 16 | G | E | -1.5297 | Soluble |
| 17 | G | E | -1.3115 | Soluble |
| 18 | S | E | -1.4696 | Soluble |
| 19 | L | E | -1.1843 | Soluble |
| 20 | R | E | -1.9344 | Soluble |
| 21 | L | E | 0.0000 | Buried |
| 22 | S | E | -0.3861 | Soluble |
| 23 | C | E | 0.0000 | Buried |
| 24 | A | E | -0.0545 | Soluble |
| 25 | A | E | 0.0000 | Buried |
| 26 | S | E | -0.5763 | Soluble |
| 27 | G | E | -1.0036 | Soluble |
| 28 | F | E | -0.3809 | Soluble |
| 29 | T | E | -0.3544 | Soluble |
| 30 | F | E | 0.0000 | Buried |
| 35 | T | E | -0.2820 | Soluble |
| 36 | S | E | -0.4906 | Soluble |
| 37 | T | E | -0.2812 | Soluble |
| 38 | G | E | 0.0000 | Buried |
| 39 | I | E | 0.0000 | Buried |
| 40 | S | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | V | E | 0.0000 | Buried |
| 43 | R | E | 0.0000 | Buried |
| 44 | Q | E | -0.8375 | Soluble |
| 45 | A | E | -1.1818 | Soluble |
| 46 | P | E | -0.9250 | Soluble |
| 47 | G | E | -1.4846 | Soluble |
| 48 | K | E | -2.4029 | Soluble |
| 49 | G | E | -1.6958 | Soluble |
| 50 | L | E | 0.0000 | Buried |
| 51 | E | E | -1.3214 | Soluble |
| 52 | W | E | 0.0000 | Buried |
| 53 | V | E | 0.0000 | Buried |
| 54 | G | E | 0.0000 | Buried |
| 55 | R | E | 0.0000 | Buried |
| 56 | T | E | -0.4548 | Soluble |
| 57 | H | E | 0.0000 | Buried |
| 58 | L | E | -0.2953 | Soluble |
| 59 | G | E | -0.9174 | Soluble |
| 62 | D | E | -1.3242 | Soluble |
| 63 | G | E | -0.9492 | Soluble |
| 64 | S | E | -0.8164 | Soluble |
| 65 | T | E | -0.7258 | Soluble |
| 66 | N | E | -1.5193 | Soluble |
| 67 | Y | E | -1.4738 | Soluble |
| 68 | A | E | -1.6581 | Soluble |
| 69 | D | E | -2.5767 | Soluble |
| 70 | S | E | -1.5711 | Soluble |
| 71 | V | E | 0.0000 | Buried |
| 72 | K | E | -2.7458 | Soluble |
| 74 | G | E | -1.8874 | Soluble |
| 75 | R | E | -1.7205 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | T | E | -1.1795 | Soluble |
| 78 | I | E | 0.0000 | Buried |
| 79 | S | E | -0.2780 | Soluble |
| 80 | A | E | -0.5964 | Soluble |
| 81 | D | E | -1.3079 | Soluble |
| 82 | T | E | -1.0756 | Soluble |
| 83 | S | E | -1.3321 | Soluble |
| 84 | K | E | -2.1162 | Soluble |
| 85 | N | E | -1.3240 | Soluble |
| 86 | T | E | 0.0000 | Buried |
| 87 | A | E | 0.0000 | Buried |
| 88 | Y | E | 0.0000 | Buried |
| 89 | L | E | 0.0000 | Buried |
| 90 | Q | E | -1.5202 | Soluble |
| 91 | M | E | 0.0000 | Buried |
| 92 | N | E | -2.1092 | Soluble |
| 93 | S | E | -1.6211 | Soluble |
| 94 | L | E | 0.0000 | Buried |
| 95 | R | E | -2.8333 | Soluble |
| 96 | A | E | -1.9471 | Soluble |
| 97 | E | E | -2.3698 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | T | E | -0.8052 | Soluble |
| 100 | A | E | 0.0000 | Buried |
| 101 | V | E | 0.2706 | Aggregation-prone |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | A | E | 0.0000 | Buried |
| 106 | R | E | -0.1207 | Soluble |
| 107 | T | E | 0.0000 | Buried |
| 108 | Y | E | 0.5321 | Aggregation-prone |
| 109 | G | E | 0.4143 | Aggregation-prone |
| 110 | I | E | 0.8703 | Aggregation-prone |
| 111 | Y | E | 1.3386 | Aggregation-prone |
| 111A | D | E | 0.4264 | Aggregation-prone |
| 111B | L | E | 1.7110 | Aggregation-prone |
| 111C | Y | E | 1.7510 | Aggregation-prone |
| 112D | V | E | 0.6690 | Aggregation-prone |
| 112C | D | E | -0.9978 | Soluble |
| 112B | Y | E | -0.2997 | Soluble |
| 112A | T | E | 0.0921 | Aggregation-prone |
| 112 | E | E | 0.0390 | Aggregation-prone |
| 113 | Y | E | 0.4263 | Aggregation-prone |
| 114 | V | E | 0.0000 | Buried |
| 115 | M | E | 0.0000 | Buried |
| 116 | D | E | 0.0000 | Buried |
| 117 | Y | E | -0.2561 | Soluble |
| 118 | W | E | 0.0000 | Buried |
| 119 | G | E | 0.0000 | Buried |
| 120 | Q | E | -1.3600 | Soluble |
| 121 | G | E | -0.6219 | Soluble |
| 122 | T | E | -0.0025 | Soluble |
| 123 | L | E | 0.2170 | Aggregation-prone |
| 124 | V | E | 0.0000 | Buried |
| 125 | T | E | 0.0000 | Buried |
| 126 | V | E | 0.0000 | Buried |
| 127 | S | E | -1.0290 | Soluble |
| 128 | S | E | -0.8416 | Soluble |
| 129 | A | E | -0.4377 | Soluble |
| 130 | S | E | -0.5839 | Soluble |
| 131 | T | E | -0.7405 | Soluble |
| 132 | K | E | -1.1927 | Soluble |
| 133 | G | E | -1.4117 | Soluble |
| 134 | P | E | 0.0000 | Buried |
| 135 | S | E | -0.3853 | Soluble |
| 136 | V | E | 0.0000 | Buried |
| 137 | F | E | 0.0000 | Buried |
| 138 | P | E | 0.0000 | Buried |
| 139 | L | E | 0.0000 | Buried |
| 140 | A | E | -0.9139 | Soluble |
| 141 | P | E | 0.0000 | Buried |
| 142 | S | E | -0.5072 | Soluble |
| 143 | G | E | -0.6798 | Soluble |
| 144 | T | E | -0.4980 | Soluble |
| 145 | A | E | -0.2665 | Soluble |
| 146 | A | E | 0.0000 | Buried |
| 147 | L | E | 0.0000 | Buried |
| 148 | G | E | 0.0000 | Buried |
| 149 | C | E | 0.0000 | Buried |
| 150 | L | E | 0.0000 | Buried |
| 151 | V | E | 0.0000 | Buried |
| 152 | K | E | -0.2919 | Soluble |
| 153 | D | E | -0.4041 | Soluble |
| 154 | Y | E | 0.0000 | Buried |
| 155 | F | E | 0.0000 | Buried |
| 156 | P | E | 0.0000 | Buried |
| 157 | E | E | -0.5783 | Soluble |
| 158 | P | E | -0.6866 | Soluble |
| 159 | V | E | -0.6220 | Soluble |
| 160 | T | E | -0.5417 | Soluble |
| 161 | V | E | -0.1761 | Soluble |
| 162 | S | E | -0.3773 | Soluble |
| 163 | W | E | 0.0000 | Buried |
| 164 | N | E | -0.6639 | Soluble |
| 165 | S | E | -0.6347 | Soluble |
| 166 | G | E | -0.5105 | Soluble |
| 167 | A | E | -0.2132 | Soluble |
| 168 | L | E | 0.0563 | Aggregation-prone |
| 169 | T | E | -0.1485 | Soluble |
| 170 | S | E | -0.1527 | Soluble |
| 171 | G | E | -0.1700 | Soluble |
| 172 | V | E | 0.1800 | Aggregation-prone |
| 173 | H | E | -0.3084 | Soluble |
| 174 | T | E | -0.0074 | Soluble |
| 175 | F | E | 0.0000 | Buried |
| 176 | P | E | -0.2577 | Soluble |
| 177 | A | E | 0.2551 | Aggregation-prone |
| 178 | V | E | 0.6089 | Aggregation-prone |
| 179 | L | E | 1.2428 | Aggregation-prone |
| 180 | Q | E | 0.2959 | Aggregation-prone |
| 181 | S | E | -0.0315 | Soluble |
| 182 | S | E | -0.1739 | Soluble |
| 183 | G | E | 0.1039 | Aggregation-prone |
| 184 | L | E | 0.1982 | Aggregation-prone |
| 185 | Y | E | 0.4406 | Aggregation-prone |
| 186 | S | E | 0.1877 | Aggregation-prone |
| 187 | L | E | 0.0000 | Buried |
| 188 | S | E | 0.0000 | Buried |
| 189 | S | E | 0.0000 | Buried |
| 190 | V | E | 0.0000 | Buried |
| 191 | V | E | 0.0000 | Buried |
| 192 | T | E | -0.1299 | Soluble |
| 193 | V | E | 0.0000 | Buried |
| 194 | P | E | -0.5887 | Soluble |
| 195 | S | E | -0.6140 | Soluble |
| 196 | S | E | -0.6036 | Soluble |
| 197 | S | E | -0.5839 | Soluble |
| 198 | L | E | -0.6537 | Soluble |
| 199 | G | E | -0.9599 | Soluble |
| 200 | T | E | -0.6219 | Soluble |
| 201 | Q | E | -0.9853 | Soluble |
| 202 | T | E | -0.8919 | Soluble |
| 203 | Y | E | 0.0000 | Buried |
| 204 | I | E | -1.0324 | Soluble |
| 205 | C | E | 0.0000 | Buried |
| 206 | N | E | -1.4089 | Soluble |
| 207 | V | E | 0.0000 | Buried |
| 208 | N | E | -1.8375 | Soluble |
| 209 | H | E | 0.0000 | Buried |
| 210 | K | E | -2.7364 | Soluble |
| 211 | P | E | -1.6743 | Soluble |
| 212 | S | E | -1.8785 | Soluble |
| 213 | N | E | -2.6265 | Soluble |
| 214 | T | E | -2.0695 | Soluble |
| 215 | K | E | -2.6654 | Soluble |
| 216 | V | E | -1.5410 | Soluble |
| 217 | D | E | -2.3176 | Soluble |
| 218 | K | E | -1.9652 | Soluble |
| 219 | K | E | -2.0826 | Soluble |
| 220 | V | E | 0.0000 | Buried |
| 221 | E | E | -2.2197 | Soluble |
| 222 | P | E | -1.5354 | Soluble |
| 223 | K | E | -1.9658 | Soluble |
| 224 | S | E | -0.8557 | Soluble |
| 225 | C | E | 0.0441 | Aggregation-prone |
| 1 | D | D | -2.4132 | Soluble |
| 2 | I | D | 0.0000 | Buried |
| 3 | Q | D | -2.3023 | Soluble |
| 4 | M | D | 0.0000 | Buried |
| 5 | T | D | -1.4461 | Soluble |
| 6 | Q | D | 0.0000 | Buried |
| 7 | S | D | -0.6939 | Soluble |
| 8 | P | D | -0.5154 | Soluble |
| 9 | S | D | -0.8831 | Soluble |
| 10 | S | D | -0.8345 | Soluble |
| 11 | L | D | -0.5975 | Soluble |
| 12 | S | D | -0.8579 | Soluble |
| 13 | A | D | 0.0000 | Buried |
| 14 | S | D | -0.8460 | Soluble |
| 15 | V | D | 0.0767 | Aggregation-prone |
| 16 | G | D | -0.7501 | Soluble |
| 17 | D | D | -1.6365 | Soluble |
| 18 | R | D | -2.3314 | Soluble |
| 19 | V | D | 0.0000 | Buried |
| 20 | T | D | -0.6328 | Soluble |
| 21 | I | D | 0.0000 | Buried |
| 22 | T | D | -0.8858 | Soluble |
| 23 | C | D | 0.0000 | Buried |
| 24 | R | D | -2.8873 | Soluble |
| 25 | A | D | 0.0000 | Buried |
| 26 | S | D | -2.1315 | Soluble |
| 27 | Q | D | -2.6387 | Soluble |
| 28 | D | D | -3.1504 | Soluble |
| 29 | V | D | 0.0000 | Buried |
| 36 | D | D | -2.7382 | Soluble |
| 37 | T | D | -1.5206 | Soluble |
| 38 | S | D | 0.0000 | Buried |
| 39 | L | D | 0.0000 | Buried |
| 40 | A | D | 0.0000 | Buried |
| 41 | W | D | 0.0000 | Buried |
| 42 | Y | D | 0.0000 | Buried |
| 43 | K | D | 0.0000 | Buried |
| 44 | Q | D | 0.0000 | Buried |
| 45 | K | D | -2.0141 | Soluble |
| 46 | P | D | -1.5786 | Soluble |
| 47 | G | D | -1.6118 | Soluble |
| 48 | K | D | -2.5287 | Soluble |
| 49 | A | D | 0.0000 | Buried |
| 50 | P | D | 0.0000 | Buried |
| 51 | K | D | -1.5714 | Soluble |
| 52 | L | D | 0.0000 | Buried |
| 53 | L | D | 0.0000 | Buried |
| 54 | I | D | 0.0000 | Buried |
| 55 | Y | D | 0.9918 | Aggregation-prone |
| 56 | S | D | 0.3717 | Aggregation-prone |
| 57 | A | D | 0.0000 | Buried |
| 65 | S | D | 0.7930 | Aggregation-prone |
| 66 | F | D | 2.2278 | Aggregation-prone |
| 67 | L | D | 1.5224 | Aggregation-prone |
| 68 | Y | D | 0.7113 | Aggregation-prone |
| 69 | S | D | 0.0423 | Aggregation-prone |
| 70 | G | D | -0.4524 | Soluble |
| 71 | V | D | 0.0000 | Buried |
| 72 | P | D | -0.3090 | Soluble |
| 74 | S | D | -0.3689 | Soluble |
| 75 | R | D | -0.7178 | Soluble |
| 76 | F | D | 0.0000 | Buried |
| 77 | S | D | 0.0438 | Aggregation-prone |
| 78 | G | D | 0.1935 | Aggregation-prone |
| 79 | S | D | -0.4127 | Soluble |
| 80 | G | D | -1.3923 | Soluble |
| 83 | S | D | -1.9649 | Soluble |
| 84 | G | D | -2.4890 | Soluble |
| 85 | T | D | -2.6228 | Soluble |
| 86 | D | D | -2.8624 | Soluble |
| 87 | F | D | 0.0000 | Buried |
| 88 | T | D | -0.8046 | Soluble |
| 89 | L | D | 0.0000 | Buried |
| 90 | T | D | -0.6005 | Soluble |
| 91 | I | D | 0.0000 | Buried |
| 92 | S | D | -1.3854 | Soluble |
| 93 | S | D | -1.1726 | Soluble |
| 94 | L | D | 0.0000 | Buried |
| 95 | Q | D | -1.1367 | Soluble |
| 96 | P | D | -1.2664 | Soluble |
| 97 | E | D | -1.9787 | Soluble |
| 98 | D | D | 0.0000 | Buried |
| 99 | F | D | 0.0000 | Buried |
| 100 | A | D | 0.0000 | Buried |
| 101 | T | D | -1.0444 | Soluble |
| 102 | Y | D | 0.0000 | Buried |
| 103 | Y | D | 0.0000 | Buried |
| 104 | C | D | 0.0000 | Buried |
| 105 | Q | D | 0.0000 | Buried |
| 106 | Q | D | 0.0000 | Buried |
| 107 | S | D | 0.0000 | Buried |
| 108 | T | D | 0.0000 | Buried |
| 109 | G | D | -1.0472 | Soluble |
| 114 | H | D | -1.2654 | Soluble |
| 115 | P | D | -1.4029 | Soluble |
| 116 | Q | D | -0.9166 | Soluble |
| 117 | T | D | -1.1000 | Soluble |
| 118 | F | D | 0.0000 | Buried |
| 119 | G | D | 0.0000 | Buried |
| 120 | Q | D | -1.8730 | Soluble |
| 121 | G | D | 0.0000 | Buried |
| 122 | T | D | 0.0000 | Buried |
| 123 | K | D | -1.6779 | Soluble |
| 124 | V | D | 0.0000 | Buried |
| 125 | E | D | -1.5822 | Soluble |
| 126 | I | D | 0.0000 | Buried |
| 127 | K | D | -1.5312 | Soluble |
| 128 | R | D | -1.0850 | Soluble |
| 129 | T | D | -0.1506 | Soluble |
| 130 | V | D | 0.5060 | Aggregation-prone |
| 131 | A | D | 0.0417 | Aggregation-prone |
| 132 | A | D | -0.0362 | Soluble |
| 133 | P | D | 0.0000 | Buried |
| 134 | S | D | -0.1654 | Soluble |
| 135 | V | D | 0.0000 | Buried |
| 136 | F | D | 0.0040 | Aggregation-prone |
| 137 | I | D | 0.0000 | Buried |
| 138 | F | D | 0.0000 | Buried |
| 139 | P | D | -0.4652 | Soluble |
| 140 | P | D | -0.6871 | Soluble |
| 141 | S | D | 0.0000 | Buried |
| 142 | D | D | -2.6653 | Soluble |
| 143 | E | D | -2.1007 | Soluble |
| 144 | Q | D | 0.0000 | Buried |
| 145 | L | D | -2.0253 | Soluble |
| 146 | K | D | -2.5222 | Soluble |
| 147 | S | D | -1.5579 | Soluble |
| 148 | G | D | -1.0053 | Soluble |
| 149 | T | D | -0.9374 | Soluble |
| 150 | A | D | 0.0000 | Buried |
| 151 | S | D | 0.0000 | Buried |
| 152 | V | D | 0.0000 | Buried |
| 153 | V | D | 0.0000 | Buried |
| 154 | C | D | 0.0000 | Buried |
| 155 | L | D | 0.0000 | Buried |
| 156 | L | D | 0.0000 | Buried |
| 157 | N | D | 0.0000 | Buried |
| 158 | N | D | -0.8564 | Soluble |
| 159 | F | D | 0.0000 | Buried |
| 160 | Y | D | 0.0000 | Buried |
| 161 | P | D | -1.7625 | Soluble |
| 162 | R | D | -2.9936 | Soluble |
| 163 | E | D | -3.1854 | Soluble |
| 164 | A | D | -2.3153 | Soluble |
| 165 | K | D | -2.2658 | Soluble |
| 166 | V | D | -1.0273 | Soluble |
| 167 | Q | D | -0.5022 | Soluble |
| 168 | W | D | 0.0000 | Buried |
| 169 | K | D | -0.4917 | Soluble |
| 170 | V | D | 0.0000 | Buried |
| 171 | D | D | -1.8563 | Soluble |
| 172 | N | D | -1.4690 | Soluble |
| 173 | A | D | -0.2142 | Soluble |
| 174 | L | D | 0.8055 | Aggregation-prone |
| 175 | Q | D | -0.2161 | Soluble |
| 176 | S | D | -0.5899 | Soluble |
| 177 | G | D | -1.2265 | Soluble |
| 178 | N | D | -1.4987 | Soluble |
| 179 | S | D | -1.3374 | Soluble |
| 180 | Q | D | -1.2911 | Soluble |
| 181 | E | D | -1.4336 | Soluble |
| 182 | S | D | -0.7921 | Soluble |
| 183 | V | D | -0.7369 | Soluble |
| 184 | T | D | -1.1973 | Soluble |
| 185 | E | D | -2.2995 | Soluble |
| 186 | Q | D | -2.0011 | Soluble |
| 187 | D | D | -1.9267 | Soluble |
| 188 | S | D | -1.9991 | Soluble |
| 189 | K | D | -2.1870 | Soluble |
| 190 | D | D | -1.5913 | Soluble |
| 191 | S | D | -1.8365 | Soluble |
| 192 | T | D | 0.0000 | Buried |
| 193 | Y | D | 0.0000 | Buried |
| 194 | S | D | 0.0000 | Buried |
| 195 | L | D | 0.0000 | Buried |
| 196 | S | D | 0.0000 | Buried |
| 197 | S | D | 0.0000 | Buried |
| 198 | T | D | -0.6905 | Soluble |
| 199 | L | D | 0.0000 | Buried |
| 200 | T | D | -0.6432 | Soluble |
| 201 | L | D | -0.8215 | Soluble |
| 202 | S | D | -1.0453 | Soluble |
| 203 | K | D | -2.0125 | Soluble |
| 204 | A | D | -1.8843 | Soluble |
| 205 | D | D | -2.6506 | Soluble |
| 206 | Y | D | 0.0000 | Buried |
| 207 | E | D | -3.4512 | Soluble |
| 208 | K | D | -3.5925 | Soluble |
| 209 | H | D | -2.9660 | Soluble |
| 210 | K | D | -3.2502 | Soluble |
| 211 | V | D | -1.5481 | Soluble |
| 212 | Y | D | 0.0000 | Buried |
| 213 | A | D | 0.0000 | Buried |
| 214 | C | D | 0.0000 | Buried |
| 215 | E | D | -0.8878 | Soluble |
| 216 | V | D | 0.0000 | Buried |
| 217 | T | D | -1.2013 | Soluble |
| 218 | H | D | 0.0000 | Buried |
| 219 | Q | D | -1.4915 | Soluble |
| 220 | G | D | -0.3524 | Soluble |
| 221 | L | D | -0.2017 | Soluble |
| 222 | S | D | -0.4376 | Soluble |
| 223 | S | D | -0.3871 | Soluble |
| 224 | P | D | -0.5713 | Soluble |
| 225 | V | D | -0.0133 | Soluble |
| 226 | T | D | -0.4822 | Soluble |
| 227 | K | D | -0.8254 | Soluble |
| 228 | S | D | -0.7313 | Soluble |
| 229 | F | D | 0.0000 | Buried |
| 230 | N | D | -1.9135 | Soluble |
| 231 | R | D | -2.4140 | Soluble |
| 232 | G | D | -1.8335 | Soluble |
| 233 | E | D | -2.0639 | Soluble |
| 234 | C | D | -0.8364 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6241 | 3.8479 | CSV PDB |
| 4.5 | -0.6695 | 3.8479 | CSV PDB |
| 5.0 | -0.7228 | 3.8479 | CSV PDB |
| 5.5 | -0.7748 | 3.8479 | CSV PDB |
| 6.0 | -0.8152 | 3.8479 | CSV PDB |
| 6.5 | -0.8354 | 3.8479 | CSV PDB |
| 7.0 | -0.8343 | 3.8479 | CSV PDB |
| 7.5 | -0.8185 | 3.8479 | CSV PDB |
| 8.0 | -0.7939 | 3.8478 | CSV PDB |
| 8.5 | -0.7624 | 3.8478 | CSV PDB |
| 9.0 | -0.7232 | 3.8475 | CSV PDB |