Vofatamab

A4DAB297 | Phase-I/II
FGFR3/CD333
G1 / None
BioClin Therapeutics Rainier Therapeutics
Phase-I/II
Whole mAb
B701 B 701 B-701 MFGR 1877A MFGR-1877A MFGR1877A
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IMGT PubChem (381126948) PubChem (404720590) PubChem (404772231) PubChem (472419471) PubChem (476262717) PubChem (476269326) PubChem (513906603) Thera-SAbDab YAbS
Avg A4D Score
-0.6557
Score Range
-0.67 to -0.64
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB297_3grw_H_L 3grw 96% -0.6385 6.5 4.0 -0.0847 -0.7152
A4DAB297_4wv1_E_D 4wv1 97% -0.6564 6.5 4.0 -0.3018 -0.7062
A4DAB297_4wv1_B_A 4wv1 97% -0.6723 6.5 4.0 -0.3025 -0.7243