Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFTSTGISWVRQAPGKGLEWVGRTHLGDGSTNYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARTYGIYDLYVDYTEYVMDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQDVDTSLAWYKQKPGKAPKLLIYSASFLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSTGHPQTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -1.9293 | Soluble |
| 2 | V | B | -0.9262 | Soluble |
| 3 | Q | B | -0.7939 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 1.2543 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.2989 | Soluble |
| 8 | G | B | -0.7474 | Soluble |
| 9 | G | B | -0.4045 | Soluble |
| 11 | G | B | -0.0586 | Soluble |
| 12 | L | B | 0.0472 | Aggregation-prone |
| 13 | V | B | -0.5511 | Soluble |
| 14 | Q | B | -1.5421 | Soluble |
| 15 | P | B | -1.8152 | Soluble |
| 16 | G | B | -1.4975 | Soluble |
| 17 | G | B | 0.0000 | Buried |
| 18 | S | B | -1.4146 | Soluble |
| 19 | L | B | -1.1796 | Soluble |
| 20 | R | B | -2.0305 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.3491 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | 0.0301 | Aggregation-prone |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.6007 | Soluble |
| 27 | G | B | -1.0571 | Soluble |
| 28 | F | B | -0.4164 | Soluble |
| 29 | T | B | -0.3679 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | T | B | -0.2710 | Soluble |
| 36 | S | B | -0.4999 | Soluble |
| 37 | T | B | -0.2892 | Soluble |
| 38 | G | B | 0.0000 | Buried |
| 39 | I | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.8576 | Soluble |
| 45 | A | B | -1.2053 | Soluble |
| 46 | P | B | -0.9487 | Soluble |
| 47 | G | B | -1.4806 | Soluble |
| 48 | K | B | -2.3949 | Soluble |
| 49 | G | B | -1.6797 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.2885 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | R | B | 0.0000 | Buried |
| 56 | T | B | 0.0000 | Buried |
| 57 | H | B | 0.0000 | Buried |
| 58 | L | B | -0.2521 | Soluble |
| 59 | G | B | -0.9072 | Soluble |
| 62 | D | B | -1.3352 | Soluble |
| 63 | G | B | -0.9423 | Soluble |
| 64 | S | B | -0.8117 | Soluble |
| 65 | T | B | -0.6993 | Soluble |
| 66 | N | B | -1.4749 | Soluble |
| 67 | Y | B | -1.3971 | Soluble |
| 68 | A | B | -1.6800 | Soluble |
| 69 | D | B | -2.5956 | Soluble |
| 70 | S | B | -1.6099 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.7893 | Soluble |
| 74 | G | B | -1.8930 | Soluble |
| 75 | R | B | -1.6926 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -1.1797 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.2939 | Soluble |
| 80 | A | B | -0.6093 | Soluble |
| 81 | D | B | -1.3587 | Soluble |
| 82 | T | B | -1.1002 | Soluble |
| 83 | S | B | -1.3410 | Soluble |
| 84 | K | B | -2.1206 | Soluble |
| 85 | N | B | -1.3124 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | 0.0000 | Buried |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.5708 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.0036 | Soluble |
| 93 | S | B | -1.5290 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.6017 | Soluble |
| 96 | A | B | -1.8307 | Soluble |
| 97 | E | B | -2.2950 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7416 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.2362 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | -0.1254 | Soluble |
| 107 | T | B | 0.0000 | Buried |
| 108 | Y | B | 0.5068 | Aggregation-prone |
| 109 | G | B | 0.3618 | Aggregation-prone |
| 110 | I | B | 0.8785 | Aggregation-prone |
| 111 | Y | B | 1.2586 | Aggregation-prone |
| 111A | D | B | 0.2333 | Aggregation-prone |
| 111B | L | B | 1.6063 | Aggregation-prone |
| 111C | Y | B | 1.6852 | Aggregation-prone |
| 112D | V | B | 0.6190 | Aggregation-prone |
| 112C | D | B | -1.0269 | Soluble |
| 112B | Y | B | -0.3347 | Soluble |
| 112A | T | B | 0.0491 | Aggregation-prone |
| 112 | E | B | 0.0118 | Aggregation-prone |
| 113 | Y | B | 0.4222 | Aggregation-prone |
| 114 | V | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | 0.0000 | Buried |
| 117 | Y | B | -0.2946 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.3410 | Soluble |
| 121 | G | B | -0.5734 | Soluble |
| 122 | T | B | 0.0310 | Aggregation-prone |
| 123 | L | B | 0.1688 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.9897 | Soluble |
| 128 | S | B | -0.8017 | Soluble |
| 129 | A | B | -0.4361 | Soluble |
| 130 | S | B | -0.5755 | Soluble |
| 131 | T | B | -0.5940 | Soluble |
| 132 | K | B | -1.1583 | Soluble |
| 133 | G | B | -1.3654 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4439 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.0875 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.0853 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -0.5544 | Soluble |
| 143 | G | B | -0.6767 | Soluble |
| 144 | T | B | -0.5032 | Soluble |
| 145 | A | B | 0.0000 | Buried |
| 146 | A | B | 0.0000 | Buried |
| 147 | L | B | 0.0000 | Buried |
| 148 | G | B | 0.0000 | Buried |
| 149 | C | B | 0.0000 | Buried |
| 150 | L | B | 0.0000 | Buried |
| 151 | V | B | 0.0000 | Buried |
| 152 | K | B | -0.2733 | Soluble |
| 153 | D | B | -0.4173 | Soluble |
| 154 | Y | B | 0.0000 | Buried |
| 155 | F | B | 0.0000 | Buried |
| 156 | P | B | 0.0000 | Buried |
| 157 | E | B | -0.5815 | Soluble |
| 158 | P | B | -0.6985 | Soluble |
| 159 | V | B | -0.6219 | Soluble |
| 160 | T | B | -0.5263 | Soluble |
| 161 | V | B | -0.1237 | Soluble |
| 162 | S | B | -0.3908 | Soluble |
| 163 | W | B | 0.0000 | Buried |
| 164 | N | B | -0.8069 | Soluble |
| 165 | S | B | -0.6660 | Soluble |
| 166 | G | B | -0.5188 | Soluble |
| 167 | A | B | -0.2212 | Soluble |
| 168 | L | B | 0.0247 | Aggregation-prone |
| 169 | T | B | -0.1576 | Soluble |
| 170 | S | B | -0.1564 | Soluble |
| 171 | G | B | -0.1767 | Soluble |
| 172 | V | B | 0.1698 | Aggregation-prone |
| 173 | H | B | -0.3048 | Soluble |
| 174 | T | B | 0.0035 | Aggregation-prone |
| 175 | F | B | 0.0000 | Buried |
| 176 | P | B | -0.2288 | Soluble |
| 177 | A | B | 0.3241 | Aggregation-prone |
| 178 | V | B | 0.7605 | Aggregation-prone |
| 179 | L | B | 1.2925 | Aggregation-prone |
| 180 | Q | B | 0.3302 | Aggregation-prone |
| 181 | S | B | -0.0174 | Soluble |
| 182 | S | B | -0.1763 | Soluble |
| 183 | G | B | 0.1212 | Aggregation-prone |
| 184 | L | B | 0.2030 | Aggregation-prone |
| 185 | Y | B | 0.4449 | Aggregation-prone |
| 186 | S | B | 0.2265 | Aggregation-prone |
| 187 | L | B | 0.0000 | Buried |
| 188 | S | B | 0.0000 | Buried |
| 189 | S | B | 0.0000 | Buried |
| 190 | V | B | 0.0000 | Buried |
| 191 | V | B | 0.0000 | Buried |
| 192 | T | B | -0.1354 | Soluble |
| 193 | V | B | 0.0000 | Buried |
| 194 | P | B | -0.6194 | Soluble |
| 195 | S | B | -0.5953 | Soluble |
| 196 | S | B | -0.6306 | Soluble |
| 197 | S | B | -0.6743 | Soluble |
| 198 | L | B | -0.8347 | Soluble |
| 199 | G | B | -1.1502 | Soluble |
| 200 | T | B | -0.7550 | Soluble |
| 201 | Q | B | -1.2937 | Soluble |
| 202 | T | B | -1.1743 | Soluble |
| 203 | Y | B | 0.0000 | Buried |
| 204 | I | B | -1.4003 | Soluble |
| 205 | C | B | 0.0000 | Buried |
| 206 | N | B | -1.4638 | Soluble |
| 207 | V | B | 0.0000 | Buried |
| 208 | N | B | -1.8031 | Soluble |
| 209 | H | B | 0.0000 | Buried |
| 210 | K | B | -2.7185 | Soluble |
| 211 | P | B | -1.6551 | Soluble |
| 212 | S | B | -1.8521 | Soluble |
| 213 | N | B | -2.6046 | Soluble |
| 214 | T | B | -2.0390 | Soluble |
| 215 | K | B | -2.6370 | Soluble |
| 216 | V | B | -1.5668 | Soluble |
| 217 | D | B | -2.4634 | Soluble |
| 218 | K | B | -2.2697 | Soluble |
| 219 | K | B | -2.5724 | Soluble |
| 220 | V | B | 0.0000 | Buried |
| 221 | E | B | -2.7712 | Soluble |
| 222 | P | B | -1.7661 | Soluble |
| 223 | K | B | -2.0545 | Soluble |
| 224 | S | B | -0.9376 | Soluble |
| 225 | C | B | -0.0245 | Soluble |
| 1 | D | A | -2.4007 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.2540 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.3348 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.6399 | Soluble |
| 8 | P | A | -0.4612 | Soluble |
| 9 | S | A | -0.7800 | Soluble |
| 10 | S | A | -0.6940 | Soluble |
| 11 | L | A | -0.5001 | Soluble |
| 12 | S | A | -0.8481 | Soluble |
| 13 | A | A | 0.0000 | Buried |
| 14 | S | A | -0.8442 | Soluble |
| 15 | V | A | -0.1786 | Soluble |
| 16 | G | A | -0.7742 | Soluble |
| 17 | D | A | -1.6197 | Soluble |
| 18 | R | A | -2.3057 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6212 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.8071 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.5989 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -2.0728 | Soluble |
| 27 | Q | A | -2.6091 | Soluble |
| 28 | D | A | -3.1105 | Soluble |
| 29 | V | A | 0.0000 | Buried |
| 36 | D | A | -2.7313 | Soluble |
| 37 | T | A | -1.5127 | Soluble |
| 38 | S | A | 0.0000 | Buried |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | K | A | -1.1369 | Soluble |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -2.0854 | Soluble |
| 46 | P | A | -1.6017 | Soluble |
| 47 | G | A | -1.6543 | Soluble |
| 48 | K | A | -2.6806 | Soluble |
| 49 | A | A | -1.8110 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.7528 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 1.0238 | Aggregation-prone |
| 56 | S | A | 0.3954 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | 0.7840 | Aggregation-prone |
| 66 | F | A | 2.2288 | Aggregation-prone |
| 67 | L | A | 1.5138 | Aggregation-prone |
| 68 | Y | A | 0.6819 | Aggregation-prone |
| 69 | S | A | 0.0265 | Aggregation-prone |
| 70 | G | A | -0.4617 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | P | A | -0.3343 | Soluble |
| 74 | S | A | -0.3952 | Soluble |
| 75 | R | A | -0.7151 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | 0.0465 | Aggregation-prone |
| 78 | G | A | 0.1928 | Aggregation-prone |
| 79 | S | A | -0.4195 | Soluble |
| 80 | G | A | -1.3652 | Soluble |
| 83 | S | A | -1.9212 | Soluble |
| 84 | G | A | -2.4445 | Soluble |
| 85 | T | A | -2.4918 | Soluble |
| 86 | D | A | -2.6690 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7625 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.5962 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.2977 | Soluble |
| 93 | S | A | -1.1051 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -1.1329 | Soluble |
| 96 | P | A | -1.3419 | Soluble |
| 97 | E | A | -2.0610 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | 0.0000 | Buried |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -0.9134 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | T | A | 0.0000 | Buried |
| 109 | G | A | -1.0267 | Soluble |
| 114 | H | A | -1.2343 | Soluble |
| 115 | P | A | -1.3445 | Soluble |
| 116 | Q | A | -0.8811 | Soluble |
| 117 | T | A | -1.0681 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.7698 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.3579 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | -1.4351 | Soluble |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -1.2453 | Soluble |
| 128 | R | A | -0.8363 | Soluble |
| 129 | T | A | -0.0021 | Soluble |
| 130 | V | A | 0.4809 | Aggregation-prone |
| 131 | A | A | -0.0020 | Soluble |
| 132 | A | A | -0.0696 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1374 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | -0.0094 | Soluble |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.4949 | Soluble |
| 140 | P | A | -0.7798 | Soluble |
| 141 | S | A | -1.6815 | Soluble |
| 142 | D | A | -2.8836 | Soluble |
| 143 | E | A | -2.5871 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1235 | Soluble |
| 146 | K | A | -2.6440 | Soluble |
| 147 | S | A | -1.6562 | Soluble |
| 148 | G | A | -1.0572 | Soluble |
| 149 | T | A | -1.0018 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8920 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.8276 | Soluble |
| 162 | R | A | -3.1758 | Soluble |
| 163 | E | A | -3.2799 | Soluble |
| 164 | A | A | -2.3713 | Soluble |
| 165 | K | A | -2.3470 | Soluble |
| 166 | V | A | -1.0946 | Soluble |
| 167 | Q | A | -0.6809 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.3910 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.4545 | Soluble |
| 172 | N | A | -1.2847 | Soluble |
| 173 | A | A | -0.0581 | Soluble |
| 174 | L | A | 0.8584 | Aggregation-prone |
| 175 | Q | A | -0.2321 | Soluble |
| 176 | S | A | -0.6080 | Soluble |
| 177 | G | A | -1.2421 | Soluble |
| 178 | N | A | -1.5390 | Soluble |
| 179 | S | A | -1.3542 | Soluble |
| 180 | Q | A | -1.2460 | Soluble |
| 181 | E | A | -1.4245 | Soluble |
| 182 | S | A | -0.7462 | Soluble |
| 183 | V | A | -0.7139 | Soluble |
| 184 | T | A | -1.1944 | Soluble |
| 185 | E | A | -2.3140 | Soluble |
| 186 | Q | A | -2.0519 | Soluble |
| 187 | D | A | -1.9937 | Soluble |
| 188 | S | A | -2.0471 | Soluble |
| 189 | K | A | -2.2233 | Soluble |
| 190 | D | A | -1.6110 | Soluble |
| 191 | S | A | -1.7749 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.6905 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.6568 | Soluble |
| 201 | L | A | -0.8538 | Soluble |
| 202 | S | A | -1.0783 | Soluble |
| 203 | K | A | -2.0699 | Soluble |
| 204 | A | A | -1.9257 | Soluble |
| 205 | D | A | -2.6542 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.4151 | Soluble |
| 208 | K | A | -3.5794 | Soluble |
| 209 | H | A | -3.0965 | Soluble |
| 210 | K | A | -3.1815 | Soluble |
| 211 | V | A | -1.3806 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -1.0873 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.2943 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.5498 | Soluble |
| 220 | G | A | -0.4031 | Soluble |
| 221 | L | A | -0.2706 | Soluble |
| 222 | S | A | -0.4705 | Soluble |
| 223 | S | A | -0.4204 | Soluble |
| 224 | P | A | -0.6169 | Soluble |
| 225 | V | A | -0.0757 | Soluble |
| 226 | T | A | -0.5865 | Soluble |
| 227 | K | A | -0.8882 | Soluble |
| 228 | S | A | -0.7901 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.9950 | Soluble |
| 231 | R | A | -2.4647 | Soluble |
| 232 | G | A | -1.8388 | Soluble |
| 233 | E | A | -2.0869 | Soluble |
| 234 | C | A | -0.8694 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6474 | 3.8511 | CSV PDB |
| 4.5 | -0.6956 | 3.8511 | CSV PDB |
| 5.0 | -0.7515 | 3.8511 | CSV PDB |
| 5.5 | -0.8057 | 3.8511 | CSV PDB |
| 6.0 | -0.8474 | 3.8511 | CSV PDB |
| 6.5 | -0.8673 | 3.8511 | CSV PDB |
| 7.0 | -0.8646 | 3.8511 | CSV PDB |
| 7.5 | -0.8464 | 3.8511 | CSV PDB |
| 8.0 | -0.8189 | 3.8511 | CSV PDB |
| 8.5 | -0.7839 | 3.851 | CSV PDB |
| 9.0 | -0.7407 | 3.8505 | CSV PDB |