Calculation Parameters
| Chain Sequence(s) |
EVQLVQSGAEVKKPGESLRISCKGSGYSFSTSWIVWVRQMPGKGLEWMGMIDPSDSFTSYSPSFQGHVTISADKSISTAYLQWSSLKASDTAMYYCARLHYYNSEEFDVWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYEIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGQSSRTRGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQFGDSQLFTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -1.7141 | Soluble |
| 2 | V | B | -0.5472 | Soluble |
| 3 | Q | B | -0.6289 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | -0.0509 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6005 | Soluble |
| 8 | G | B | -0.5257 | Soluble |
| 9 | A | B | 0.0290 | Aggregation-prone |
| 11 | E | B | -0.1092 | Soluble |
| 12 | V | B | 0.4565 | Aggregation-prone |
| 13 | K | B | -0.9386 | Soluble |
| 14 | K | B | -1.6742 | Soluble |
| 15 | P | B | -1.8004 | Soluble |
| 16 | G | B | -1.8668 | Soluble |
| 17 | E | B | -1.8645 | Soluble |
| 18 | S | B | -1.7276 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | R | B | -2.1164 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | S | B | 0.0000 | Buried |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -0.4624 | Soluble |
| 25 | G | B | -0.3219 | Soluble |
| 26 | S | B | -0.6268 | Soluble |
| 27 | G | B | -0.8387 | Soluble |
| 28 | Y | B | -0.3166 | Soluble |
| 29 | S | B | -0.2070 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -0.8626 | Soluble |
| 36 | T | B | -0.0187 | Soluble |
| 37 | S | B | 0.0000 | Buried |
| 38 | W | B | 0.3439 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | V | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | -1.0265 | Soluble |
| 44 | Q | B | -1.0933 | Soluble |
| 45 | M | B | -0.9433 | Soluble |
| 46 | P | B | -0.8924 | Soluble |
| 47 | G | B | -1.4098 | Soluble |
| 48 | K | B | -2.4398 | Soluble |
| 49 | G | B | -1.7893 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -2.1995 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | M | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | M | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | D | B | 0.0000 | Buried |
| 58 | P | B | 0.0000 | Buried |
| 59 | S | B | -1.1896 | Soluble |
| 62 | D | B | -1.6007 | Soluble |
| 63 | S | B | -0.3944 | Soluble |
| 64 | F | B | 1.3047 | Aggregation-prone |
| 65 | T | B | 0.6940 | Aggregation-prone |
| 66 | S | B | 0.2269 | Aggregation-prone |
| 67 | Y | B | -0.4959 | Soluble |
| 68 | S | B | 0.0000 | Buried |
| 69 | P | B | -0.9071 | Soluble |
| 70 | S | B | -0.9906 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | Q | B | -1.6929 | Soluble |
| 74 | G | B | -1.3485 | Soluble |
| 75 | H | B | -1.2693 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -0.8036 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.5882 | Soluble |
| 80 | A | B | -0.8048 | Soluble |
| 81 | D | B | -1.4228 | Soluble |
| 82 | K | B | -1.7322 | Soluble |
| 83 | S | B | -0.3468 | Soluble |
| 84 | I | B | 0.8213 | Aggregation-prone |
| 85 | S | B | -0.3207 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | 0.0000 | Buried |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.3181 | Soluble |
| 91 | W | B | 0.0000 | Buried |
| 92 | S | B | -1.2322 | Soluble |
| 93 | S | B | -1.4857 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | K | B | -2.3613 | Soluble |
| 96 | A | B | -1.2239 | Soluble |
| 97 | S | B | -0.7834 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.2577 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | M | B | -0.0955 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | L | B | 0.0000 | Buried |
| 108 | H | B | -0.7984 | Soluble |
| 109 | Y | B | 0.3027 | Aggregation-prone |
| 110 | Y | B | 0.6469 | Aggregation-prone |
| 111 | N | B | -0.8437 | Soluble |
| 112 | S | B | -0.7538 | Soluble |
| 113 | E | B | -0.5722 | Soluble |
| 114 | E | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | -0.9294 | Soluble |
| 117 | V | B | -0.4872 | Soluble |
| 118 | W | B | -0.5025 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.2497 | Soluble |
| 121 | G | B | -0.6655 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.3317 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.7004 | Soluble |
| 128 | S | B | -0.8490 | Soluble |
| 129 | A | B | -0.4632 | Soluble |
| 130 | S | B | -0.5627 | Soluble |
| 131 | T | B | -0.5932 | Soluble |
| 132 | K | B | -1.2739 | Soluble |
| 133 | G | B | -1.4352 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.2719 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1465 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.7580 | Soluble |
| 141 | P | B | -0.5975 | Soluble |
| 142 | C | B | -0.6104 | Soluble |
| 143 | S | B | -0.8055 | Soluble |
| 144 | R | B | -1.4060 | Soluble |
| 145 | S | B | -0.9891 | Soluble |
| 146 | T | B | -1.4054 | Soluble |
| 147 | S | B | -1.4874 | Soluble |
| 148 | E | B | -2.2718 | Soluble |
| 149 | S | B | -1.3145 | Soluble |
| 150 | T | B | -0.9033 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | -0.2938 | Soluble |
| 159 | D | B | -0.4580 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.5861 | Soluble |
| 164 | P | B | -0.8583 | Soluble |
| 165 | V | B | 0.0000 | Buried |
| 166 | T | B | -0.4125 | Soluble |
| 167 | V | B | -0.3153 | Soluble |
| 168 | S | B | -0.4416 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -1.0209 | Soluble |
| 171 | S | B | -0.7490 | Soluble |
| 172 | G | B | -0.4847 | Soluble |
| 173 | A | B | -0.2059 | Soluble |
| 174 | L | B | -0.0064 | Soluble |
| 175 | T | B | -0.1198 | Soluble |
| 176 | S | B | -0.3054 | Soluble |
| 177 | G | B | -0.3079 | Soluble |
| 178 | V | B | 0.2175 | Aggregation-prone |
| 179 | H | B | 0.0000 | Buried |
| 180 | T | B | -0.0926 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.2894 | Soluble |
| 183 | A | B | 0.1780 | Aggregation-prone |
| 184 | V | B | 0.4249 | Aggregation-prone |
| 185 | L | B | 1.1475 | Aggregation-prone |
| 186 | Q | B | 0.1896 | Aggregation-prone |
| 187 | S | B | -0.2201 | Soluble |
| 188 | S | B | -0.2225 | Soluble |
| 189 | G | B | -0.0180 | Soluble |
| 190 | L | B | -0.0228 | Soluble |
| 191 | Y | B | 0.0000 | Buried |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.2660 | Aggregation-prone |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1301 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.5769 | Soluble |
| 201 | S | B | -0.9614 | Soluble |
| 202 | S | B | -0.7484 | Soluble |
| 203 | S | B | 0.0000 | Buried |
| 204 | L | B | -0.8908 | Soluble |
| 205 | G | B | -0.9050 | Soluble |
| 206 | T | B | -0.9823 | Soluble |
| 207 | K | B | -1.7705 | Soluble |
| 208 | T | B | -1.5410 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | T | B | -1.8550 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.5425 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | D | B | -1.7494 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.7240 | Soluble |
| 217 | P | B | -1.6819 | Soluble |
| 218 | S | B | -1.8361 | Soluble |
| 219 | N | B | -2.5408 | Soluble |
| 220 | T | B | -2.0488 | Soluble |
| 221 | K | B | -2.5390 | Soluble |
| 222 | V | B | -1.5782 | Soluble |
| 223 | D | B | -2.6344 | Soluble |
| 224 | K | B | -2.1717 | Soluble |
| 225 | R | B | -2.8345 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.7328 | Soluble |
| 228 | S | B | -1.5596 | Soluble |
| 229 | K | B | -1.5902 | Soluble |
| 230 | Y | B | -0.0536 | Soluble |
| 1 | E | A | -1.6871 | Soluble |
| 2 | I | A | -0.4323 | Soluble |
| 3 | V | A | 0.8320 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.6920 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.8009 | Soluble |
| 8 | P | A | -0.5320 | Soluble |
| 9 | G | A | -0.7847 | Soluble |
| 10 | T | A | -0.2835 | Soluble |
| 11 | L | A | 0.0291 | Aggregation-prone |
| 12 | S | A | -0.2476 | Soluble |
| 13 | L | A | -0.7820 | Soluble |
| 14 | S | A | -1.4974 | Soluble |
| 15 | P | A | -2.0623 | Soluble |
| 16 | G | A | -2.3017 | Soluble |
| 17 | E | A | -2.8600 | Soluble |
| 18 | R | A | -3.0339 | Soluble |
| 19 | A | A | 0.0000 | Buried |
| 20 | T | A | -0.5022 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.7600 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.0880 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.6241 | Soluble |
| 27 | Q | A | -0.7321 | Soluble |
| 28 | S | A | -0.0733 | Soluble |
| 29 | V | A | 1.1545 | Aggregation-prone |
| 30 | S | A | 0.0608 | Aggregation-prone |
| 36 | S | A | -0.2655 | Soluble |
| 37 | S | A | -0.3912 | Soluble |
| 38 | Y | A | -0.2366 | Soluble |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.6993 | Soluble |
| 46 | P | A | -1.4027 | Soluble |
| 47 | G | A | -1.3679 | Soluble |
| 48 | Q | A | -1.9464 | Soluble |
| 49 | A | A | -1.4287 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -1.9835 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | -0.4864 | Soluble |
| 56 | G | A | -0.9342 | Soluble |
| 57 | Q | A | -1.4761 | Soluble |
| 65 | S | A | -1.0783 | Soluble |
| 66 | S | A | -1.0700 | Soluble |
| 67 | R | A | -1.7877 | Soluble |
| 68 | T | A | -1.6814 | Soluble |
| 69 | R | A | -2.2408 | Soluble |
| 70 | G | A | -1.6610 | Soluble |
| 71 | I | A | -1.3372 | Soluble |
| 72 | P | A | -1.4846 | Soluble |
| 74 | D | A | -2.1116 | Soluble |
| 75 | R | A | -1.8993 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.8019 | Soluble |
| 78 | G | A | -0.6637 | Soluble |
| 79 | S | A | -0.8400 | Soluble |
| 80 | G | A | -1.2364 | Soluble |
| 83 | S | A | -1.0866 | Soluble |
| 84 | G | A | -0.7949 | Soluble |
| 85 | T | A | -1.4339 | Soluble |
| 86 | D | A | -1.8342 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7656 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.7740 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -2.3167 | Soluble |
| 93 | R | A | -3.3088 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | E | A | -2.5394 | Soluble |
| 96 | P | A | -1.7074 | Soluble |
| 97 | E | A | -2.3364 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.5528 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | -0.1413 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | F | A | 0.0334 | Aggregation-prone |
| 108 | G | A | 0.0000 | Buried |
| 109 | D | A | -1.8199 | Soluble |
| 113 | S | A | -1.4151 | Soluble |
| 114 | Q | A | -1.1826 | Soluble |
| 115 | L | A | -0.4176 | Soluble |
| 116 | F | A | 0.0000 | Buried |
| 117 | T | A | -0.2462 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.5572 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.4125 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | -0.4805 | Soluble |
| 127 | K | A | -1.1527 | Soluble |
| 128 | R | A | -0.9555 | Soluble |
| 129 | T | A | 0.0273 | Aggregation-prone |
| 130 | V | A | 0.8120 | Aggregation-prone |
| 131 | A | A | 0.2825 | Aggregation-prone |
| 132 | A | A | 0.0422 | Aggregation-prone |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.0213 | Soluble |
| 135 | V | A | 0.0367 | Aggregation-prone |
| 136 | F | A | 0.0514 | Aggregation-prone |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.5607 | Soluble |
| 140 | P | A | -0.6616 | Soluble |
| 141 | S | A | -1.5385 | Soluble |
| 142 | D | A | -2.9868 | Soluble |
| 143 | E | A | -3.0285 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1997 | Soluble |
| 146 | K | A | -2.7577 | Soluble |
| 147 | S | A | -1.6874 | Soluble |
| 148 | G | A | -1.4667 | Soluble |
| 149 | T | A | -1.1484 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | -0.2108 | Soluble |
| 158 | N | A | -0.5339 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.0769 | Soluble |
| 162 | R | A | -1.7479 | Soluble |
| 163 | E | A | -2.7205 | Soluble |
| 164 | A | A | -2.0185 | Soluble |
| 165 | K | A | -2.2403 | Soluble |
| 166 | V | A | -1.0730 | Soluble |
| 167 | Q | A | -0.6577 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.7560 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -2.0763 | Soluble |
| 172 | N | A | -1.5022 | Soluble |
| 173 | A | A | -0.4868 | Soluble |
| 174 | L | A | 0.2715 | Aggregation-prone |
| 175 | Q | A | -0.5582 | Soluble |
| 176 | S | A | -0.8725 | Soluble |
| 177 | G | A | -1.4211 | Soluble |
| 178 | N | A | -1.8579 | Soluble |
| 179 | S | A | -1.8077 | Soluble |
| 180 | Q | A | -1.9644 | Soluble |
| 181 | E | A | -2.0817 | Soluble |
| 182 | S | A | -0.8146 | Soluble |
| 183 | V | A | -0.4895 | Soluble |
| 184 | T | A | -0.9002 | Soluble |
| 185 | E | A | -2.0189 | Soluble |
| 186 | Q | A | -1.5226 | Soluble |
| 187 | D | A | -1.5858 | Soluble |
| 188 | S | A | -1.5754 | Soluble |
| 189 | K | A | -2.1701 | Soluble |
| 190 | D | A | -1.5934 | Soluble |
| 191 | S | A | -1.5337 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.9619 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.6976 | Soluble |
| 201 | L | A | -0.9629 | Soluble |
| 202 | S | A | -1.2621 | Soluble |
| 203 | K | A | -2.1443 | Soluble |
| 204 | A | A | -2.0080 | Soluble |
| 205 | D | A | -3.0883 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.8413 | Soluble |
| 208 | K | A | -3.8890 | Soluble |
| 209 | H | A | -3.2828 | Soluble |
| 210 | K | A | -3.3039 | Soluble |
| 211 | V | A | -1.5498 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.8540 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1734 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.5874 | Soluble |
| 220 | G | A | -0.3439 | Soluble |
| 221 | L | A | -0.3701 | Soluble |
| 222 | S | A | -0.4631 | Soluble |
| 223 | S | A | -0.4103 | Soluble |
| 224 | P | A | -0.5957 | Soluble |
| 225 | V | A | -0.0139 | Soluble |
| 226 | T | A | -0.4813 | Soluble |
| 227 | K | A | -0.7858 | Soluble |
| 228 | S | A | -0.6084 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.8858 | Soluble |
| 231 | R | A | -2.6882 | Soluble |
| 232 | G | A | -2.0171 | Soluble |
| 233 | E | A | -2.2367 | Soluble |
| 234 | C | A | -0.7708 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7744 | 3.7777 | CSV PDB |
| 4.5 | -0.8241 | 3.6511 | CSV PDB |
| 5.0 | -0.8836 | 3.5174 | CSV PDB |
| 5.5 | -0.9419 | 3.3812 | CSV PDB |
| 6.0 | -0.986 | 3.2445 | CSV PDB |
| 6.5 | -1.006 | 3.108 | CSV PDB |
| 7.0 | -1.001 | 2.9731 | CSV PDB |
| 7.5 | -0.9789 | 2.843 | CSV PDB |
| 8.0 | -0.9474 | 2.7263 | CSV PDB |
| 8.5 | -0.9091 | 2.6374 | CSV PDB |
| 9.0 | -0.8642 | 2.586 | CSV PDB |