Denecimig

A4DAB083 | Cardiovascular / hemostasis disorders | Phase-III
F9;F10
G4;G4 / IgG4
Genmab Novo Nordisk
Phase-III
Bispecific mAb
NN-7769 NN7769 NNC0365-3769 Mim8 Mim-8
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IMGT PubChem (471299237) PubChem (474492340) PubChem (485483309) PubChem (485511883) PubChem (494431296) Thera-SAbDab YAbS
Avg A4D Score
-0.7305
Score Range
-0.74 to -0.71
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB083_7ahu_H_L 7ahu 100% -0.7416 6.5 4.0 -0.4396 -0.7796
A4DAB083_7ahu_B_A 7ahu 100% -0.7102 6.5 4.0 -0.3172 -0.7597
A4DAB083_7ahv_A_B 7ahv 99% -0.7396 6.5 4.0 -0.4837 -0.7719