Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLEQPGGSLRLSCAGSGFTFRDYAMTWVRQAPGKGLEWVSSISGSGGNTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRLSITIRPRYYGLDVWGQGTTVTVSSASTKGPSVFPLAPCSRSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVEDIVMTQSPLSLPVTPGEPASISCRSSQSLLYSIGYNYLDWYLQKSGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGFYYCMQALQTPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -1.7455 | Soluble |
| 2 | V | A | -0.6132 | Soluble |
| 3 | Q | A | -0.8470 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.7547 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.7132 | Soluble |
| 8 | G | A | -1.1757 | Soluble |
| 9 | G | A | -0.8928 | Soluble |
| 11 | G | A | -0.7090 | Soluble |
| 12 | L | A | -0.3706 | Soluble |
| 13 | E | A | -1.2607 | Soluble |
| 14 | Q | A | -1.9250 | Soluble |
| 15 | P | A | -1.8388 | Soluble |
| 16 | G | A | -1.5374 | Soluble |
| 17 | G | A | -1.2862 | Soluble |
| 18 | S | A | -1.2011 | Soluble |
| 19 | L | A | -1.2396 | Soluble |
| 20 | R | A | -2.0541 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4461 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.1722 | Soluble |
| 25 | G | A | -0.3704 | Soluble |
| 26 | S | A | -0.5925 | Soluble |
| 27 | G | A | -0.7214 | Soluble |
| 28 | F | A | -0.2500 | Soluble |
| 29 | T | A | -0.6214 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | R | A | -1.6674 | Soluble |
| 36 | D | A | -0.4437 | Soluble |
| 37 | Y | A | -0.3394 | Soluble |
| 38 | A | A | 0.0000 | Buried |
| 39 | M | A | 0.0000 | Buried |
| 40 | T | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.8124 | Soluble |
| 44 | Q | A | -1.0716 | Soluble |
| 45 | A | A | -1.3452 | Soluble |
| 46 | P | A | -1.0350 | Soluble |
| 47 | G | A | -1.4887 | Soluble |
| 48 | K | A | -2.5053 | Soluble |
| 49 | G | A | -1.7781 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.7101 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | S | A | 0.0000 | Buried |
| 55 | S | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | -0.7489 | Soluble |
| 58 | G | A | 0.0000 | Buried |
| 59 | S | A | -0.9616 | Soluble |
| 62 | G | A | -1.2840 | Soluble |
| 63 | G | A | -1.2739 | Soluble |
| 64 | N | A | -1.4741 | Soluble |
| 65 | T | A | -0.4401 | Soluble |
| 66 | Y | A | 0.0590 | Aggregation-prone |
| 67 | Y | A | -0.5024 | Soluble |
| 68 | A | A | -1.3378 | Soluble |
| 69 | D | A | -2.4483 | Soluble |
| 70 | S | A | -1.6444 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5645 | Soluble |
| 74 | G | A | -1.7770 | Soluble |
| 75 | R | A | -1.5470 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.7467 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.3647 | Soluble |
| 80 | R | A | -1.1130 | Soluble |
| 81 | D | A | -1.6595 | Soluble |
| 82 | N | A | -2.0522 | Soluble |
| 83 | S | A | -1.7633 | Soluble |
| 84 | K | A | -2.3296 | Soluble |
| 85 | N | A | -2.0097 | Soluble |
| 86 | T | A | -1.1381 | Soluble |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.5579 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.1395 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.3109 | Soluble |
| 93 | S | A | -1.2674 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.4801 | Soluble |
| 96 | A | A | -1.8739 | Soluble |
| 97 | E | A | -2.2533 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9026 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1125 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | K | A | -0.2547 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | R | A | -0.4751 | Soluble |
| 109 | L | A | 0.0000 | Buried |
| 110 | S | A | 0.0768 | Aggregation-prone |
| 111 | I | A | 1.1098 | Aggregation-prone |
| 111A | T | A | 0.9167 | Aggregation-prone |
| 111B | I | A | 1.3814 | Aggregation-prone |
| 112C | R | A | -0.7539 | Soluble |
| 112B | P | A | -0.7428 | Soluble |
| 112A | R | A | -0.9255 | Soluble |
| 112 | Y | A | 0.0000 | Buried |
| 113 | Y | A | 0.0650 | Aggregation-prone |
| 114 | G | A | 0.0000 | Buried |
| 115 | L | A | 0.0000 | Buried |
| 116 | D | A | -0.7748 | Soluble |
| 117 | V | A | -0.4792 | Soluble |
| 118 | W | A | -0.3826 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.1950 | Soluble |
| 121 | G | A | -0.5402 | Soluble |
| 122 | T | A | -0.4412 | Soluble |
| 123 | T | A | 0.0000 | Buried |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.9082 | Soluble |
| 128 | S | A | -0.6902 | Soluble |
| 129 | A | A | -0.5571 | Soluble |
| 130 | S | A | -0.7441 | Soluble |
| 131 | T | A | -0.8899 | Soluble |
| 132 | K | A | -1.6351 | Soluble |
| 133 | G | A | -1.6031 | Soluble |
| 134 | P | A | -0.7527 | Soluble |
| 135 | S | A | -0.3439 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.5981 | Soluble |
| 138 | P | A | -1.0435 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.4961 | Soluble |
| 141 | P | A | -0.5226 | Soluble |
| 142 | C | A | -1.0013 | Soluble |
| 143 | S | A | -1.4298 | Soluble |
| 144 | R | A | -2.5409 | Soluble |
| 145 | S | A | -1.4790 | Soluble |
| 146 | E | A | -2.2437 | Soluble |
| 147 | S | A | -1.2375 | Soluble |
| 148 | T | A | -0.7839 | Soluble |
| 149 | A | A | -0.5277 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | G | A | 0.0000 | Buried |
| 153 | C | A | 0.0000 | Buried |
| 154 | L | A | 0.0000 | Buried |
| 155 | V | A | 0.0000 | Buried |
| 156 | K | A | 0.0000 | Buried |
| 157 | D | A | -0.5917 | Soluble |
| 158 | Y | A | 0.0000 | Buried |
| 159 | F | A | -0.4032 | Soluble |
| 160 | P | A | 0.0000 | Buried |
| 161 | E | A | -0.3840 | Soluble |
| 162 | P | A | -0.4943 | Soluble |
| 163 | V | A | -0.5016 | Soluble |
| 164 | T | A | -0.4793 | Soluble |
| 165 | V | A | -0.0253 | Soluble |
| 166 | S | A | -0.3396 | Soluble |
| 167 | W | A | 0.0000 | Buried |
| 168 | N | A | -0.8683 | Soluble |
| 169 | S | A | -0.6922 | Soluble |
| 170 | G | A | -0.5406 | Soluble |
| 171 | A | A | -0.2282 | Soluble |
| 172 | L | A | 0.0123 | Aggregation-prone |
| 173 | T | A | -0.1139 | Soluble |
| 174 | S | A | -0.1197 | Soluble |
| 175 | G | A | -0.0949 | Soluble |
| 176 | V | A | 0.2706 | Aggregation-prone |
| 177 | H | A | -0.0533 | Soluble |
| 178 | T | A | 0.0235 | Aggregation-prone |
| 179 | F | A | 0.0000 | Buried |
| 180 | P | A | -0.4673 | Soluble |
| 181 | A | A | 0.2349 | Aggregation-prone |
| 182 | V | A | 0.5352 | Aggregation-prone |
| 183 | L | A | 1.4004 | Aggregation-prone |
| 184 | Q | A | 0.3105 | Aggregation-prone |
| 185 | S | A | -0.0388 | Soluble |
| 186 | S | A | -0.2622 | Soluble |
| 187 | G | A | -0.0383 | Soluble |
| 188 | L | A | 0.1116 | Aggregation-prone |
| 189 | Y | A | 0.4275 | Aggregation-prone |
| 190 | S | A | 0.2650 | Aggregation-prone |
| 191 | L | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | S | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | V | A | 0.0000 | Buried |
| 196 | T | A | -0.0820 | Soluble |
| 197 | V | A | 0.0000 | Buried |
| 198 | P | A | -0.4908 | Soluble |
| 199 | S | A | -0.6776 | Soluble |
| 200 | S | A | -0.6605 | Soluble |
| 201 | S | A | -0.5535 | Soluble |
| 202 | L | A | -0.4506 | Soluble |
| 203 | G | A | -0.7053 | Soluble |
| 204 | T | A | -0.9660 | Soluble |
| 205 | K | A | -1.7168 | Soluble |
| 206 | T | A | -1.5037 | Soluble |
| 207 | Y | A | 0.0000 | Buried |
| 208 | T | A | 0.0000 | Buried |
| 209 | C | A | 0.0000 | Buried |
| 210 | N | A | 0.0000 | Buried |
| 211 | V | A | 0.0000 | Buried |
| 212 | D | A | -1.7091 | Soluble |
| 213 | H | A | 0.0000 | Buried |
| 214 | K | A | -2.7660 | Soluble |
| 215 | P | A | -1.5861 | Soluble |
| 216 | S | A | -1.8536 | Soluble |
| 217 | N | A | -2.4810 | Soluble |
| 218 | T | A | -2.0882 | Soluble |
| 219 | K | A | -2.6424 | Soluble |
| 220 | V | A | -1.5122 | Soluble |
| 221 | D | A | -2.6829 | Soluble |
| 222 | K | A | -2.2633 | Soluble |
| 223 | R | A | -2.8896 | Soluble |
| 224 | V | A | 0.0000 | Buried |
| 225 | E | A | -2.2296 | Soluble |
| 1 | D | B | -1.7484 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.8355 | Aggregation-prone |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -0.6091 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.4567 | Soluble |
| 8 | P | B | -0.2139 | Soluble |
| 9 | L | B | 0.1237 | Aggregation-prone |
| 10 | S | B | -0.3274 | Soluble |
| 11 | L | B | 0.0000 | Buried |
| 12 | P | B | -0.9014 | Soluble |
| 13 | V | B | -1.0945 | Soluble |
| 14 | T | B | -1.7421 | Soluble |
| 15 | P | B | -1.9572 | Soluble |
| 16 | G | B | -2.0748 | Soluble |
| 17 | E | B | -2.7185 | Soluble |
| 18 | P | B | -2.2079 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | S | B | -0.7530 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | S | B | -0.9655 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.9865 | Soluble |
| 25 | S | B | 0.0000 | Buried |
| 26 | S | B | -0.9168 | Soluble |
| 27 | Q | B | -1.5700 | Soluble |
| 28 | S | B | -0.7519 | Soluble |
| 29 | L | B | 0.0000 | Buried |
| 30 | L | B | 1.4581 | Aggregation-prone |
| 31 | Y | B | 2.0816 | Aggregation-prone |
| 32 | S | B | 1.7047 | Aggregation-prone |
| 34 | I | B | 2.2515 | Aggregation-prone |
| 35 | G | B | 0.9969 | Aggregation-prone |
| 36 | Y | B | 1.4238 | Aggregation-prone |
| 37 | N | B | 0.0000 | Buried |
| 38 | Y | B | 0.6750 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | D | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | L | B | -0.3967 | Soluble |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.4161 | Soluble |
| 46 | S | B | -1.1571 | Soluble |
| 47 | G | B | -1.5246 | Soluble |
| 48 | Q | B | -1.9744 | Soluble |
| 49 | S | B | -1.3566 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | Q | B | -1.2948 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.1569 | Soluble |
| 56 | L | B | 0.1661 | Aggregation-prone |
| 57 | G | B | 0.0000 | Buried |
| 65 | S | B | -0.7756 | Soluble |
| 66 | N | B | -1.0918 | Soluble |
| 67 | R | B | -1.8062 | Soluble |
| 68 | A | B | -1.0732 | Soluble |
| 69 | S | B | -0.8818 | Soluble |
| 70 | G | B | -0.9949 | Soluble |
| 71 | V | B | -1.1075 | Soluble |
| 72 | P | B | -1.3362 | Soluble |
| 74 | D | B | -2.2084 | Soluble |
| 75 | R | B | -1.9471 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.3432 | Soluble |
| 78 | G | B | -0.8303 | Soluble |
| 79 | S | B | -0.7680 | Soluble |
| 80 | G | B | -1.0564 | Soluble |
| 83 | S | B | -0.6243 | Soluble |
| 84 | G | B | -0.7216 | Soluble |
| 85 | T | B | -1.6360 | Soluble |
| 86 | D | B | -2.2234 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -1.0231 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | K | B | -1.6057 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.2947 | Soluble |
| 93 | R | B | -3.1622 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.7425 | Soluble |
| 96 | A | B | -2.4955 | Soluble |
| 97 | E | B | -2.8422 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | V | B | 0.0000 | Buried |
| 100 | G | B | 0.0000 | Buried |
| 101 | F | B | -0.2832 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | M | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | A | B | 0.0000 | Buried |
| 108 | L | B | 0.1560 | Aggregation-prone |
| 109 | Q | B | -1.3252 | Soluble |
| 114 | T | B | -0.7430 | Soluble |
| 115 | P | B | -1.0413 | Soluble |
| 116 | Y | B | 0.0000 | Buried |
| 117 | T | B | -0.3846 | Soluble |
| 118 | F | B | -0.1135 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.2552 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.0048 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -1.4125 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.6838 | Soluble |
| 128 | R | B | -1.1192 | Soluble |
| 129 | T | B | 0.1514 | Aggregation-prone |
| 130 | V | B | 1.3666 | Aggregation-prone |
| 131 | A | B | 0.6949 | Aggregation-prone |
| 132 | A | B | 0.3242 | Aggregation-prone |
| 133 | P | B | 0.1064 | Aggregation-prone |
| 134 | S | B | -0.0885 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | -0.1069 | Soluble |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4939 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.3890 | Soluble |
| 142 | D | B | -2.5994 | Soluble |
| 143 | E | B | -2.3869 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.7999 | Soluble |
| 146 | K | B | -2.5035 | Soluble |
| 147 | S | B | -1.5430 | Soluble |
| 148 | G | B | -1.1457 | Soluble |
| 149 | T | B | -0.7274 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.5186 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.4510 | Soluble |
| 162 | R | B | -2.9726 | Soluble |
| 163 | E | B | -3.1001 | Soluble |
| 164 | A | B | -2.2119 | Soluble |
| 165 | K | B | -2.2326 | Soluble |
| 166 | V | B | -1.0330 | Soluble |
| 167 | Q | B | -0.3895 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.4481 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.1727 | Soluble |
| 172 | N | B | -1.1291 | Soluble |
| 173 | A | B | -0.1384 | Soluble |
| 174 | L | B | 0.7883 | Aggregation-prone |
| 175 | Q | B | -0.1540 | Soluble |
| 176 | S | B | -0.3714 | Soluble |
| 177 | G | B | -0.9032 | Soluble |
| 178 | N | B | -0.7951 | Soluble |
| 179 | S | B | -1.1744 | Soluble |
| 180 | Q | B | -1.4573 | Soluble |
| 181 | E | B | -2.0222 | Soluble |
| 182 | S | B | -1.0127 | Soluble |
| 183 | V | B | -0.7672 | Soluble |
| 184 | T | B | -0.7626 | Soluble |
| 185 | E | B | -1.5032 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -1.8865 | Soluble |
| 188 | S | B | -2.4251 | Soluble |
| 189 | K | B | -2.7520 | Soluble |
| 190 | D | B | -1.9931 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | -1.0733 | Soluble |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7618 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3931 | Soluble |
| 201 | L | B | -0.5736 | Soluble |
| 202 | S | B | -1.1138 | Soluble |
| 203 | K | B | -1.9621 | Soluble |
| 204 | A | B | -1.7376 | Soluble |
| 205 | D | B | -2.4760 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.6765 | Soluble |
| 208 | K | B | -3.4823 | Soluble |
| 209 | H | B | -2.8320 | Soluble |
| 210 | K | B | -3.2058 | Soluble |
| 211 | V | B | -1.1081 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7755 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.9939 | Soluble |
| 218 | Q | B | -1.2790 | Soluble |
| 219 | G | B | -0.8265 | Soluble |
| 220 | T | B | -0.4075 | Soluble |
| 221 | T | B | -0.2488 | Soluble |
| 222 | S | B | -0.4160 | Soluble |
| 223 | V | B | 0.1481 | Aggregation-prone |
| 224 | T | B | -0.4363 | Soluble |
| 225 | K | B | -0.9306 | Soluble |
| 226 | S | B | -0.6236 | Soluble |
| 227 | F | B | 0.0000 | Buried |
| 228 | N | B | -1.9708 | Soluble |
| 229 | R | B | -2.7278 | Soluble |
| 230 | G | B | -2.2507 | Soluble |
| 231 | E | B | -2.9849 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7292 | 3.1092 | CSV PDB |
| 4.5 | -0.7741 | 3.1092 | CSV PDB |
| 5.0 | -0.8282 | 3.1092 | CSV PDB |
| 5.5 | -0.8814 | 3.1092 | CSV PDB |
| 6.0 | -0.9218 | 3.1092 | CSV PDB |
| 6.5 | -0.9397 | 3.1092 | CSV PDB |
| 7.0 | -0.934 | 3.1092 | CSV PDB |
| 7.5 | -0.9123 | 3.1092 | CSV PDB |
| 8.0 | -0.8818 | 3.1091 | CSV PDB |
| 8.5 | -0.8453 | 3.1087 | CSV PDB |
| 9.0 | -0.8028 | 3.1075 | CSV PDB |