Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSDYGIAWVRQAPGKGLEWVAFISDLAYTIYYADTVTGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDNWDAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITRSSQSLVHNNANTYLHWYQQKPGKAPKLLIYKVSNRFSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCSQNTLVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.0900 | Soluble |
| 2 | V | B | -1.1738 | Soluble |
| 3 | Q | B | -1.2722 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.9833 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.2042 | Soluble |
| 8 | G | B | -0.8144 | Soluble |
| 9 | G | B | -0.4055 | Soluble |
| 11 | G | B | -0.0289 | Soluble |
| 12 | L | B | 0.0028 | Aggregation-prone |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.6145 | Soluble |
| 15 | P | B | -1.7427 | Soluble |
| 16 | G | B | -1.4254 | Soluble |
| 17 | G | B | 0.0000 | Buried |
| 18 | S | B | -1.3086 | Soluble |
| 19 | L | B | -1.1905 | Soluble |
| 20 | R | B | -2.1537 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.3846 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.0883 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9083 | Soluble |
| 27 | G | B | -1.1525 | Soluble |
| 28 | F | B | -0.6853 | Soluble |
| 29 | T | B | -0.6461 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -1.1061 | Soluble |
| 36 | D | B | -1.7303 | Soluble |
| 37 | Y | B | -0.6796 | Soluble |
| 38 | G | B | 0.0000 | Buried |
| 39 | I | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.8657 | Soluble |
| 45 | A | B | -1.2177 | Soluble |
| 46 | P | B | -0.9211 | Soluble |
| 47 | G | B | -1.4626 | Soluble |
| 48 | K | B | -2.3679 | Soluble |
| 49 | G | B | -1.6430 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.3583 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | F | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | S | B | 0.0000 | Buried |
| 58 | D | B | -0.0554 | Soluble |
| 59 | L | B | 1.0353 | Aggregation-prone |
| 62 | A | B | 1.0985 | Aggregation-prone |
| 63 | Y | B | 1.7875 | Aggregation-prone |
| 64 | T | B | 1.2245 | Aggregation-prone |
| 65 | I | B | 1.4131 | Aggregation-prone |
| 66 | Y | B | 0.9668 | Aggregation-prone |
| 67 | Y | B | 0.2626 | Aggregation-prone |
| 68 | A | B | 0.0000 | Buried |
| 69 | D | B | -2.0086 | Soluble |
| 70 | T | B | -1.2826 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | T | B | -0.8736 | Soluble |
| 74 | G | B | -0.9733 | Soluble |
| 75 | R | B | -0.9006 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -0.5340 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.1512 | Soluble |
| 80 | R | B | -0.8140 | Soluble |
| 81 | D | B | -1.4247 | Soluble |
| 82 | N | B | -1.6972 | Soluble |
| 83 | S | B | -1.5867 | Soluble |
| 84 | K | B | -2.3432 | Soluble |
| 85 | N | B | -1.6530 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | -0.6056 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.4162 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -1.5498 | Soluble |
| 93 | S | B | -1.2545 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.4353 | Soluble |
| 96 | A | B | -1.7760 | Soluble |
| 97 | E | B | -2.2865 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7413 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.2129 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | D | B | 0.0000 | Buried |
| 108 | N | B | -0.3833 | Soluble |
| 109 | W | B | 0.1340 | Aggregation-prone |
| 113 | D | B | -0.1648 | Soluble |
| 114 | A | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | 0.0000 | Buried |
| 117 | Y | B | -0.0889 | Soluble |
| 118 | W | B | -0.3109 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.2931 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.1061 | Aggregation-prone |
| 123 | L | B | 0.2599 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.9900 | Soluble |
| 128 | S | B | -0.7004 | Soluble |
| 129 | A | B | -0.4284 | Soluble |
| 130 | S | B | -0.5654 | Soluble |
| 131 | T | B | -0.7144 | Soluble |
| 132 | K | B | -1.1393 | Soluble |
| 133 | G | B | -1.4045 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.3085 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -0.7524 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.0023 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.0531 | Soluble |
| 143 | S | B | -1.1752 | Soluble |
| 144 | K | B | -2.0731 | Soluble |
| 145 | S | B | -1.1342 | Soluble |
| 146 | T | B | -0.9642 | Soluble |
| 147 | S | B | -0.8818 | Soluble |
| 148 | G | B | -0.9470 | Soluble |
| 149 | G | B | -0.8857 | Soluble |
| 150 | T | B | -0.6036 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.2416 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.5084 | Soluble |
| 164 | P | B | -0.7904 | Soluble |
| 165 | V | B | -0.8484 | Soluble |
| 166 | T | B | -0.7949 | Soluble |
| 167 | V | B | -0.3029 | Soluble |
| 168 | S | B | -0.4708 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.7579 | Soluble |
| 171 | S | B | -0.6716 | Soluble |
| 172 | G | B | -0.5930 | Soluble |
| 173 | A | B | -0.2667 | Soluble |
| 174 | L | B | -0.0255 | Soluble |
| 175 | T | B | -0.1933 | Soluble |
| 176 | S | B | -0.1829 | Soluble |
| 177 | G | B | -0.2093 | Soluble |
| 178 | V | B | 0.1357 | Aggregation-prone |
| 179 | H | B | -0.2846 | Soluble |
| 180 | T | B | 0.0284 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.2942 | Soluble |
| 183 | A | B | 0.2306 | Aggregation-prone |
| 184 | V | B | 0.5236 | Aggregation-prone |
| 185 | L | B | 1.2232 | Aggregation-prone |
| 186 | Q | B | 0.0000 | Buried |
| 187 | S | B | -0.0240 | Soluble |
| 188 | S | B | -0.1079 | Soluble |
| 189 | G | B | 0.1944 | Aggregation-prone |
| 190 | L | B | 0.2630 | Aggregation-prone |
| 191 | Y | B | 0.4797 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1185 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6015 | Soluble |
| 201 | S | B | 0.0000 | Buried |
| 202 | S | B | -0.6563 | Soluble |
| 203 | S | B | 0.0000 | Buried |
| 204 | L | B | -0.6661 | Soluble |
| 205 | G | B | -0.8877 | Soluble |
| 206 | T | B | -0.5977 | Soluble |
| 207 | Q | B | -0.9283 | Soluble |
| 208 | T | B | -0.9121 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.0525 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.6165 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.5513 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.9012 | Soluble |
| 217 | P | B | -1.6492 | Soluble |
| 218 | S | B | -1.8835 | Soluble |
| 219 | N | B | -2.6567 | Soluble |
| 220 | T | B | -2.2471 | Soluble |
| 221 | K | B | -2.9300 | Soluble |
| 222 | V | B | -1.6765 | Soluble |
| 223 | D | B | -2.5473 | Soluble |
| 224 | K | B | -2.0094 | Soluble |
| 225 | K | B | -2.2701 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.2412 | Soluble |
| 228 | P | B | -1.7703 | Soluble |
| 229 | K | B | -2.4058 | Soluble |
| 230 | S | B | -1.2013 | Soluble |
| 231 | C | B | -0.6981 | Soluble |
| 1 | D | A | -2.1853 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.2481 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.3528 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.7373 | Soluble |
| 8 | P | A | -0.5431 | Soluble |
| 9 | S | A | -0.8485 | Soluble |
| 10 | S | A | -0.8220 | Soluble |
| 11 | L | A | -0.5564 | Soluble |
| 12 | S | A | -0.7235 | Soluble |
| 13 | A | A | -0.9600 | Soluble |
| 14 | S | A | -0.8421 | Soluble |
| 15 | V | A | 0.0691 | Aggregation-prone |
| 16 | G | A | -0.6496 | Soluble |
| 17 | D | A | -1.7850 | Soluble |
| 18 | R | A | -2.2820 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6475 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.7804 | Soluble |
| 24 | R | A | -2.5849 | Soluble |
| 25 | S | A | -1.8726 | Soluble |
| 26 | S | A | -1.7848 | Soluble |
| 27 | Q | A | -1.5677 | Soluble |
| 28 | S | A | -0.6328 | Soluble |
| 29 | L | A | 0.0000 | Buried |
| 30 | V | A | 0.2905 | Aggregation-prone |
| 31 | H | A | -0.8443 | Soluble |
| 32 | N | A | -1.8508 | Soluble |
| 34 | N | A | -1.9531 | Soluble |
| 35 | A | A | -1.0196 | Soluble |
| 36 | N | A | -1.0502 | Soluble |
| 37 | T | A | -0.2989 | Soluble |
| 38 | Y | A | 0.1330 | Aggregation-prone |
| 39 | L | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -1.3002 | Soluble |
| 45 | K | A | -1.8831 | Soluble |
| 46 | P | A | -1.5007 | Soluble |
| 47 | G | A | -1.8204 | Soluble |
| 48 | K | A | -2.5785 | Soluble |
| 49 | A | A | -1.6472 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.3332 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | -0.4891 | Soluble |
| 56 | K | A | -0.6766 | Soluble |
| 57 | V | A | -0.6429 | Soluble |
| 65 | S | A | -0.9390 | Soluble |
| 66 | N | A | -1.3551 | Soluble |
| 67 | R | A | -1.8843 | Soluble |
| 68 | F | A | -1.0009 | Soluble |
| 69 | S | A | -0.7492 | Soluble |
| 70 | G | A | -0.7972 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | P | A | -0.6749 | Soluble |
| 74 | S | A | -0.7916 | Soluble |
| 75 | R | A | -0.9770 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.8312 | Soluble |
| 78 | G | A | -0.7088 | Soluble |
| 79 | S | A | -0.6872 | Soluble |
| 80 | G | A | -0.9318 | Soluble |
| 83 | S | A | -0.4331 | Soluble |
| 84 | G | A | -0.5067 | Soluble |
| 85 | T | A | -1.1861 | Soluble |
| 86 | D | A | -1.6441 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.6599 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6309 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.4435 | Soluble |
| 93 | S | A | -1.1092 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -0.8844 | Soluble |
| 96 | P | A | -1.4055 | Soluble |
| 97 | E | A | -1.7726 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -1.0812 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -0.8464 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | N | A | 0.3188 | Aggregation-prone |
| 108 | T | A | 0.1040 | Aggregation-prone |
| 109 | L | A | 0.8704 | Aggregation-prone |
| 114 | V | A | 1.3430 | Aggregation-prone |
| 115 | P | A | 0.2890 | Aggregation-prone |
| 116 | W | A | 0.0000 | Buried |
| 117 | T | A | -0.4596 | Soluble |
| 118 | F | A | -0.4888 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.5684 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.4407 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | -1.2830 | Soluble |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -1.5877 | Soluble |
| 128 | R | A | -1.0959 | Soluble |
| 129 | T | A | -0.1840 | Soluble |
| 130 | V | A | 0.5728 | Aggregation-prone |
| 131 | A | A | 0.1614 | Aggregation-prone |
| 132 | A | A | -0.0951 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1326 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0367 | Aggregation-prone |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.7266 | Soluble |
| 140 | P | A | 0.0000 | Buried |
| 141 | S | A | -1.4391 | Soluble |
| 142 | D | A | -2.2253 | Soluble |
| 143 | E | A | -2.0120 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | 0.0000 | Buried |
| 146 | K | A | -2.5451 | Soluble |
| 147 | S | A | -1.6219 | Soluble |
| 148 | G | A | -1.2872 | Soluble |
| 149 | T | A | -1.0171 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.9172 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.8081 | Soluble |
| 162 | R | A | -3.0058 | Soluble |
| 163 | E | A | -3.1491 | Soluble |
| 164 | A | A | -2.3533 | Soluble |
| 165 | K | A | -2.4617 | Soluble |
| 166 | V | A | -1.3051 | Soluble |
| 167 | Q | A | -0.7039 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6120 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.9525 | Soluble |
| 172 | N | A | -1.3693 | Soluble |
| 173 | A | A | -0.3562 | Soluble |
| 174 | L | A | 0.4878 | Aggregation-prone |
| 175 | Q | A | -0.2435 | Soluble |
| 176 | S | A | -0.5270 | Soluble |
| 177 | G | A | -0.9461 | Soluble |
| 178 | N | A | -0.9360 | Soluble |
| 179 | S | A | -1.0830 | Soluble |
| 180 | Q | A | -1.2833 | Soluble |
| 181 | E | A | -1.6864 | Soluble |
| 182 | S | A | -0.8813 | Soluble |
| 183 | V | A | -0.7090 | Soluble |
| 184 | T | A | -1.0173 | Soluble |
| 185 | E | A | -1.9974 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.0430 | Soluble |
| 188 | S | A | -2.0142 | Soluble |
| 189 | K | A | -2.4218 | Soluble |
| 190 | D | A | -1.7393 | Soluble |
| 191 | S | A | -1.9123 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.5980 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.4262 | Soluble |
| 201 | L | A | -0.5950 | Soluble |
| 202 | S | A | -1.0016 | Soluble |
| 203 | K | A | -1.9717 | Soluble |
| 204 | A | A | -1.6780 | Soluble |
| 205 | D | A | -2.2784 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.0680 | Soluble |
| 208 | K | A | -3.3817 | Soluble |
| 209 | H | A | -2.9653 | Soluble |
| 210 | K | A | -3.0395 | Soluble |
| 211 | V | A | -1.5466 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.9400 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.2629 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.7072 | Soluble |
| 220 | G | A | -0.3661 | Soluble |
| 221 | L | A | -0.2307 | Soluble |
| 222 | S | A | -0.4641 | Soluble |
| 223 | S | A | -0.4399 | Soluble |
| 224 | P | A | -0.6309 | Soluble |
| 225 | V | A | -0.0949 | Soluble |
| 226 | T | A | -0.5100 | Soluble |
| 227 | K | A | -0.7210 | Soluble |
| 228 | S | A | -0.6938 | Soluble |
| 229 | F | A | -1.2453 | Soluble |
| 230 | N | A | -2.3773 | Soluble |
| 231 | R | A | -2.5800 | Soluble |
| 232 | G | A | -2.0138 | Soluble |
| 233 | E | A | -2.1553 | Soluble |
| 234 | C | A | -0.4042 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7433 | 2.3004 | CSV PDB |
| 4.5 | -0.7818 | 2.2811 | CSV PDB |
| 5.0 | -0.8258 | 2.2611 | CSV PDB |
| 5.5 | -0.8668 | 2.2407 | CSV PDB |
| 6.0 | -0.8944 | 2.2202 | CSV PDB |
| 6.5 | -0.8999 | 2.1998 | CSV PDB |
| 7.0 | -0.8828 | 2.1797 | CSV PDB |
| 7.5 | -0.851 | 2.1605 | CSV PDB |
| 8.0 | -0.8112 | 2.1434 | CSV PDB |
| 8.5 | -0.7654 | 2.1305 | CSV PDB |
| 9.0 | -0.7136 | 2.1219 | CSV PDB |