Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVEPGGSLRLSCAVSGFDFEKAWMSWVRQAPGQGLQWVARIKSTADGGTTSYAAPVEGRFIISRDDSRNMLYLQMNSLKTEDTAVYYCTSAHWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSYELTQPPSVSVSPGQTARITCSGEALPMQFAHWYQQRPGKAPVIVVYKDSERPSGVPERFSGSSSGTTATLTITGVQAEDEADYYCQSPDSTNTYEVFGGGTKLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -1.9980 | Soluble |
| 2 | V | A | -1.2614 | Soluble |
| 3 | Q | A | -1.5456 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.2372 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.5073 | Soluble |
| 8 | G | A | -0.8491 | Soluble |
| 9 | G | A | -0.3631 | Soluble |
| 11 | G | A | 0.0179 | Aggregation-prone |
| 12 | L | A | -0.0783 | Soluble |
| 13 | V | A | -0.8494 | Soluble |
| 14 | E | A | -2.1580 | Soluble |
| 15 | P | A | -1.8872 | Soluble |
| 16 | G | A | -1.4443 | Soluble |
| 17 | G | A | -1.1408 | Soluble |
| 18 | S | A | -1.1115 | Soluble |
| 19 | L | A | -0.7964 | Soluble |
| 20 | R | A | -1.5716 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4416 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.3448 | Soluble |
| 25 | V | A | 0.0000 | Buried |
| 26 | S | A | -1.2591 | Soluble |
| 27 | G | A | -1.3313 | Soluble |
| 28 | F | A | -1.5609 | Soluble |
| 29 | D | A | -2.8117 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | E | A | -3.4043 | Soluble |
| 36 | K | A | -3.2494 | Soluble |
| 37 | A | A | -1.5952 | Soluble |
| 38 | W | A | -0.6132 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6451 | Soluble |
| 45 | A | A | -0.9756 | Soluble |
| 46 | P | A | -0.8113 | Soluble |
| 47 | G | A | -1.3024 | Soluble |
| 48 | Q | A | -1.7722 | Soluble |
| 49 | G | A | -1.1926 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | Q | A | -0.8930 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | R | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | K | A | -1.1679 | Soluble |
| 58 | S | A | 0.0000 | Buried |
| 59 | T | A | -1.5734 | Soluble |
| 60 | A | A | -1.5054 | Soluble |
| 61 | D | A | -1.9911 | Soluble |
| 62 | G | A | -1.3146 | Soluble |
| 63 | G | A | -0.9101 | Soluble |
| 64 | T | A | -0.6298 | Soluble |
| 65 | T | A | 0.0890 | Aggregation-prone |
| 66 | S | A | -0.0710 | Soluble |
| 67 | Y | A | -0.3141 | Soluble |
| 68 | A | A | -0.5740 | Soluble |
| 69 | A | A | -0.6939 | Soluble |
| 70 | P | A | -1.0006 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | E | A | -1.9175 | Soluble |
| 74 | G | A | -1.3105 | Soluble |
| 75 | R | A | -1.0100 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | I | A | 0.5962 | Aggregation-prone |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.0931 | Soluble |
| 80 | R | A | -1.1056 | Soluble |
| 81 | D | A | -1.5875 | Soluble |
| 82 | D | A | -2.1586 | Soluble |
| 83 | S | A | -1.7811 | Soluble |
| 84 | R | A | -2.3556 | Soluble |
| 85 | N | A | -2.0117 | Soluble |
| 86 | M | A | -0.9025 | Soluble |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -0.5482 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -0.9529 | Soluble |
| 93 | S | A | -1.1406 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | K | A | -2.0875 | Soluble |
| 96 | T | A | -1.7994 | Soluble |
| 97 | E | A | -2.1962 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6797 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2772 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | T | A | 0.0000 | Buried |
| 106 | S | A | -0.0356 | Soluble |
| 116 | A | A | 0.0210 | Aggregation-prone |
| 117 | H | A | -0.1244 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4369 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | -0.0322 | Soluble |
| 123 | L | A | 0.1997 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.4697 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.2275 | Soluble |
| 128 | S | A | -0.9647 | Soluble |
| 129 | A | A | -0.5451 | Soluble |
| 130 | S | A | -0.6285 | Soluble |
| 131 | T | A | -0.7063 | Soluble |
| 132 | K | A | -1.1022 | Soluble |
| 133 | G | A | -1.3647 | Soluble |
| 134 | P | A | -0.6167 | Soluble |
| 135 | S | A | -0.2711 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | 0.0000 | Buried |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2347 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.8695 | Soluble |
| 143 | G | A | -0.6243 | Soluble |
| 144 | T | A | -0.4568 | Soluble |
| 145 | A | A | -0.2949 | Soluble |
| 146 | A | A | -0.1168 | Soluble |
| 147 | L | A | 0.0000 | Buried |
| 148 | G | A | 0.0000 | Buried |
| 149 | C | A | 0.0000 | Buried |
| 150 | L | A | 0.0000 | Buried |
| 151 | V | A | 0.0000 | Buried |
| 152 | K | A | 0.0000 | Buried |
| 153 | D | A | -0.2345 | Soluble |
| 154 | Y | A | 0.0000 | Buried |
| 155 | F | A | 0.0000 | Buried |
| 156 | P | A | 0.0000 | Buried |
| 157 | E | A | -0.5649 | Soluble |
| 158 | P | A | -0.8883 | Soluble |
| 159 | V | A | -0.9036 | Soluble |
| 160 | T | A | -0.7692 | Soluble |
| 161 | V | A | -0.4963 | Soluble |
| 162 | S | A | -0.4762 | Soluble |
| 163 | W | A | 0.0000 | Buried |
| 164 | N | A | -0.7487 | Soluble |
| 165 | S | A | -0.6471 | Soluble |
| 166 | G | A | -0.5660 | Soluble |
| 167 | A | A | -0.2393 | Soluble |
| 168 | L | A | -0.0420 | Soluble |
| 169 | T | A | -0.2529 | Soluble |
| 170 | S | A | -0.3392 | Soluble |
| 171 | G | A | -0.5964 | Soluble |
| 172 | V | A | -0.0370 | Soluble |
| 173 | H | A | -0.2753 | Soluble |
| 174 | T | A | -0.0120 | Soluble |
| 175 | F | A | 0.0000 | Buried |
| 176 | P | A | -0.0053 | Soluble |
| 177 | A | A | 0.1694 | Aggregation-prone |
| 178 | V | A | 0.0000 | Buried |
| 179 | L | A | 1.1368 | Aggregation-prone |
| 180 | Q | A | 0.1585 | Aggregation-prone |
| 181 | S | A | -0.2401 | Soluble |
| 182 | S | A | -0.1862 | Soluble |
| 183 | G | A | 0.0432 | Aggregation-prone |
| 184 | L | A | 0.1587 | Aggregation-prone |
| 185 | Y | A | 0.4025 | Aggregation-prone |
| 186 | S | A | 0.0000 | Buried |
| 187 | L | A | 0.0000 | Buried |
| 188 | S | A | 0.0000 | Buried |
| 189 | S | A | 0.0000 | Buried |
| 190 | V | A | 0.0000 | Buried |
| 191 | V | A | 0.0000 | Buried |
| 192 | T | A | -0.2535 | Soluble |
| 193 | V | A | 0.0000 | Buried |
| 194 | P | A | -0.4531 | Soluble |
| 195 | S | A | -0.5509 | Soluble |
| 196 | S | A | -0.6142 | Soluble |
| 197 | S | A | -0.6143 | Soluble |
| 198 | L | A | -0.8252 | Soluble |
| 199 | G | A | -0.9891 | Soluble |
| 200 | T | A | -0.7498 | Soluble |
| 201 | Q | A | -1.2402 | Soluble |
| 202 | T | A | -1.1537 | Soluble |
| 203 | Y | A | 0.0000 | Buried |
| 204 | I | A | -1.2559 | Soluble |
| 205 | C | A | 0.0000 | Buried |
| 206 | N | A | -1.6095 | Soluble |
| 207 | V | A | 0.0000 | Buried |
| 208 | N | A | -2.3949 | Soluble |
| 209 | H | A | 0.0000 | Buried |
| 210 | K | A | -2.9049 | Soluble |
| 211 | P | A | -1.6357 | Soluble |
| 212 | S | A | -1.9057 | Soluble |
| 213 | N | A | -2.6550 | Soluble |
| 214 | T | A | -2.2057 | Soluble |
| 215 | K | A | -2.8612 | Soluble |
| 216 | V | A | -1.7109 | Soluble |
| 217 | D | A | -2.4501 | Soluble |
| 218 | K | A | -2.2300 | Soluble |
| 219 | R | A | -2.5637 | Soluble |
| 220 | V | A | 0.0000 | Buried |
| 221 | E | A | -2.8880 | Soluble |
| 222 | P | A | -1.9344 | Soluble |
| 223 | K | A | -2.2938 | Soluble |
| 1 | S | B | -0.6294 | Soluble |
| 2 | Y | B | 0.0000 | Buried |
| 3 | E | B | -2.1977 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.8812 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | P | B | -0.5603 | Soluble |
| 8 | P | B | -0.8909 | Soluble |
| 9 | S | B | -0.8765 | Soluble |
| 11 | V | B | -0.7067 | Soluble |
| 12 | S | B | -0.4092 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | S | B | -0.3571 | Soluble |
| 15 | P | B | -0.9671 | Soluble |
| 16 | G | B | -1.3753 | Soluble |
| 17 | Q | B | -1.6683 | Soluble |
| 18 | T | B | -1.3759 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | R | B | -1.8601 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.5491 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | S | B | -0.8738 | Soluble |
| 25 | G | B | 0.0000 | Buried |
| 26 | E | B | -2.1829 | Soluble |
| 27 | A | B | 0.0000 | Buried |
| 28 | L | B | 0.0000 | Buried |
| 29 | P | B | -0.1375 | Soluble |
| 36 | M | B | 0.7426 | Aggregation-prone |
| 37 | Q | B | 0.5036 | Aggregation-prone |
| 38 | F | B | 1.2574 | Aggregation-prone |
| 39 | A | B | 0.0000 | Buried |
| 40 | H | B | -0.2373 | Soluble |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -0.9616 | Soluble |
| 45 | R | B | -1.8901 | Soluble |
| 46 | P | B | -1.5886 | Soluble |
| 47 | G | B | -1.7913 | Soluble |
| 48 | K | B | -2.3365 | Soluble |
| 49 | A | B | -1.2040 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | V | B | 0.8628 | Aggregation-prone |
| 52 | I | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | V | B | 0.0000 | Buried |
| 55 | Y | B | -0.8344 | Soluble |
| 56 | K | B | -1.0090 | Soluble |
| 57 | D | B | -0.9251 | Soluble |
| 65 | S | B | -1.5417 | Soluble |
| 66 | E | B | -2.6806 | Soluble |
| 67 | R | B | -2.4945 | Soluble |
| 68 | P | B | -1.2307 | Soluble |
| 69 | S | B | -1.0517 | Soluble |
| 70 | G | B | -0.9080 | Soluble |
| 71 | V | B | -0.7401 | Soluble |
| 72 | P | B | -1.3123 | Soluble |
| 74 | E | B | -2.2659 | Soluble |
| 75 | R | B | -1.4443 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.4026 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.8332 | Soluble |
| 80 | S | B | -0.4045 | Soluble |
| 83 | S | B | -0.6203 | Soluble |
| 84 | G | B | -0.8731 | Soluble |
| 85 | T | B | -0.9421 | Soluble |
| 86 | T | B | -0.6687 | Soluble |
| 87 | A | B | 0.0000 | Buried |
| 88 | T | B | -0.6780 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8817 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | T | B | -1.2618 | Soluble |
| 93 | G | B | -1.0918 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | Q | B | -1.4976 | Soluble |
| 96 | A | B | -1.2961 | Soluble |
| 97 | E | B | -2.3343 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | E | B | -1.3465 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | D | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | -0.0319 | Soluble |
| 106 | S | B | 0.0000 | Buried |
| 107 | P | B | 0.0000 | Buried |
| 108 | D | B | 0.0000 | Buried |
| 109 | S | B | -0.5034 | Soluble |
| 110 | T | B | -0.2388 | Soluble |
| 113 | N | B | -0.3977 | Soluble |
| 114 | T | B | -0.2410 | Soluble |
| 115 | Y | B | 0.0504 | Aggregation-prone |
| 116 | E | B | -0.3208 | Soluble |
| 117 | V | B | -0.4830 | Soluble |
| 118 | F | B | -0.4833 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -1.1972 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -2.0100 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | T | B | -0.4675 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | L | B | 0.7179 | Aggregation-prone |
| 128 | S | B | -0.4675 | Soluble |
| 129 | Q | B | -0.7691 | Soluble |
| 130 | P | B | -1.0583 | Soluble |
| 131 | K | B | -2.0968 | Soluble |
| 132 | A | B | -1.3514 | Soluble |
| 133 | A | B | -0.7432 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4871 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | T | B | -0.3534 | Soluble |
| 138 | L | B | 0.0000 | Buried |
| 139 | F | B | 0.0000 | Buried |
| 140 | P | B | -0.0727 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -0.8815 | Soluble |
| 143 | S | B | -1.3896 | Soluble |
| 144 | E | B | -1.8363 | Soluble |
| 145 | E | B | 0.0000 | Buried |
| 146 | L | B | -1.6710 | Soluble |
| 147 | Q | B | -2.0510 | Soluble |
| 148 | A | B | -1.5741 | Soluble |
| 149 | N | B | -2.2794 | Soluble |
| 150 | K | B | -1.8179 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | T | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | V | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | I | B | 0.0000 | Buried |
| 158 | S | B | -0.6019 | Soluble |
| 159 | D | B | -1.4684 | Soluble |
| 160 | F | B | 0.0000 | Buried |
| 161 | Y | B | 0.0000 | Buried |
| 162 | P | B | -0.7912 | Soluble |
| 163 | G | B | -0.6632 | Soluble |
| 164 | A | B | -0.1977 | Soluble |
| 165 | V | B | -0.1342 | Soluble |
| 166 | T | B | -0.1123 | Soluble |
| 167 | V | B | 0.0893 | Aggregation-prone |
| 168 | A | B | -0.3992 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | K | B | -0.9687 | Soluble |
| 171 | A | B | 0.0000 | Buried |
| 172 | D | B | -1.2741 | Soluble |
| 173 | S | B | -0.8542 | Soluble |
| 174 | S | B | -0.7827 | Soluble |
| 175 | P | B | -0.8869 | Soluble |
| 176 | V | B | -0.8546 | Soluble |
| 177 | K | B | -1.7496 | Soluble |
| 178 | A | B | -0.9149 | Soluble |
| 179 | G | B | -0.8464 | Soluble |
| 180 | V | B | -0.6869 | Soluble |
| 181 | E | B | -0.7865 | Soluble |
| 182 | T | B | -0.1935 | Soluble |
| 183 | T | B | 0.0000 | Buried |
| 184 | T | B | -0.0937 | Soluble |
| 185 | P | B | -0.2765 | Soluble |
| 186 | S | B | -0.7562 | Soluble |
| 187 | K | B | -1.6462 | Soluble |
| 188 | Q | B | -1.5693 | Soluble |
| 189 | S | B | -1.4332 | Soluble |
| 190 | N | B | -2.0490 | Soluble |
| 191 | N | B | -2.5175 | Soluble |
| 192 | K | B | -2.0054 | Soluble |
| 193 | Y | B | -1.1072 | Soluble |
| 194 | A | B | 0.0000 | Buried |
| 195 | A | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | Y | B | 0.0000 | Buried |
| 199 | L | B | 0.0000 | Buried |
| 200 | S | B | -0.5185 | Soluble |
| 201 | L | B | -1.0340 | Soluble |
| 202 | T | B | -1.6334 | Soluble |
| 203 | P | B | -2.2933 | Soluble |
| 204 | E | B | -3.1753 | Soluble |
| 205 | Q | B | -2.5142 | Soluble |
| 206 | W | B | 0.0000 | Buried |
| 207 | K | B | -3.1742 | Soluble |
| 208 | S | B | -2.4986 | Soluble |
| 209 | H | B | -2.4036 | Soluble |
| 210 | R | B | -2.4803 | Soluble |
| 211 | S | B | -1.4568 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | S | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | Q | B | -0.6799 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.5430 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | E | B | -2.2953 | Soluble |
| 220 | G | B | -1.4543 | Soluble |
| 221 | S | B | -0.8632 | Soluble |
| 222 | T | B | -0.4563 | Soluble |
| 223 | V | B | -0.1602 | Soluble |
| 224 | E | B | -1.0452 | Soluble |
| 225 | K | B | -1.2327 | Soluble |
| 226 | T | B | -0.7417 | Soluble |
| 227 | V | B | -0.3330 | Soluble |
| 228 | A | B | -0.8218 | Soluble |
| 229 | P | B | -1.0067 | Soluble |
| 230 | T | B | -0.6936 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.5959 | 3.1294 | CSV PDB |
| 4.5 | -0.6389 | 3.12 | CSV PDB |
| 5.0 | -0.6923 | 3.116 | CSV PDB |
| 5.5 | -0.745 | 3.1261 | CSV PDB |
| 6.0 | -0.7847 | 3.1599 | CSV PDB |
| 6.5 | -0.8009 | 3.2154 | CSV PDB |
| 7.0 | -0.7918 | 3.2827 | CSV PDB |
| 7.5 | -0.7657 | 3.3551 | CSV PDB |
| 8.0 | -0.731 | 3.4302 | CSV PDB |
| 8.5 | -0.6914 | 3.5086 | CSV PDB |
| 9.0 | -0.6483 | 3.5905 | CSV PDB |