Cinpanemab

A4DAB065 | Phase-II
SNCA/PARK1/PARK4
G1 / None
Neurimmune Therapeutics Biogen
Phase-II
Whole mAb
BIIB 054 BIIB-054 BIIB054
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IMGT PubChem (336908608) PubChem (381128265) PubChem (472419912) PubChem (476262690) PubChem (476269293) PubChem (496703301) Thera-SAbDab YAbS
Avg A4D Score
-0.7188
Score Range
-0.74 to -0.69
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB065_6ct7_H_L 6ct7 100% -0.7444 6.5 4.0 -0.6612 -0.7536
A4DAB065_6ct7_A_B 6ct7 100% -0.6933 6.5 4.0 -0.6425 -0.699