Calculation Parameters
| Chain Sequence(s) |
QVQLQQPGAECVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTCVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFCECPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCQIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKCGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVECEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTCQDSKDCTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.1372 | Soluble |
| 2 | V | A | -0.3253 | Soluble |
| 3 | Q | A | -1.0181 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | Q | A | -1.6276 | Soluble |
| 6 | Q | A | -1.0095 | Soluble |
| 7 | P | A | -0.8638 | Soluble |
| 8 | G | A | -0.8993 | Soluble |
| 9 | A | A | 0.0000 | Buried |
| 11 | E | A | -0.6814 | Soluble |
| 12 | C | A | -0.5222 | Soluble |
| 13 | V | A | -0.5014 | Soluble |
| 14 | K | A | -1.1912 | Soluble |
| 15 | P | A | -1.0161 | Soluble |
| 16 | G | A | -0.9602 | Soluble |
| 17 | A | A | -0.7148 | Soluble |
| 18 | S | A | -0.9680 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.7147 | Soluble |
| 21 | M | A | 0.0000 | Buried |
| 22 | S | A | -0.7343 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.2312 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.7499 | Soluble |
| 27 | G | A | -0.5664 | Soluble |
| 28 | Y | A | -0.0944 | Soluble |
| 29 | T | A | 0.0321 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | -0.6930 | Soluble |
| 36 | S | A | -0.0830 | Soluble |
| 37 | Y | A | 0.4786 | Aggregation-prone |
| 38 | N | A | -0.0374 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | K | A | 0.0000 | Buried |
| 44 | Q | A | -0.4759 | Soluble |
| 45 | T | A | 0.0000 | Buried |
| 46 | P | A | -0.9034 | Soluble |
| 47 | G | A | -1.2868 | Soluble |
| 48 | R | A | -1.7608 | Soluble |
| 49 | G | A | -1.1703 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8752 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | I | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | A | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.6201 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | G | A | -1.3834 | Soluble |
| 62 | N | A | -2.0906 | Soluble |
| 63 | G | A | -2.0011 | Soluble |
| 64 | D | A | -2.2575 | Soluble |
| 65 | T | A | -1.0958 | Soluble |
| 66 | S | A | -0.9931 | Soluble |
| 67 | Y | A | -1.3498 | Soluble |
| 68 | N | A | -2.1545 | Soluble |
| 69 | Q | A | -2.8857 | Soluble |
| 70 | K | A | -2.9239 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | K | A | -2.8713 | Soluble |
| 74 | G | A | -1.9420 | Soluble |
| 75 | K | A | -1.5991 | Soluble |
| 76 | A | A | 0.0000 | Buried |
| 77 | T | A | -0.8371 | Soluble |
| 78 | L | A | 0.0000 | Buried |
| 79 | T | A | -0.7218 | Soluble |
| 80 | A | A | -1.1041 | Soluble |
| 81 | D | A | -1.6273 | Soluble |
| 82 | K | A | -2.3528 | Soluble |
| 83 | S | A | -1.2971 | Soluble |
| 84 | S | A | -0.9881 | Soluble |
| 85 | S | A | -1.1330 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.4477 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | Q | A | -1.1457 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -0.8508 | Soluble |
| 93 | S | A | -0.7682 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | T | A | -1.1643 | Soluble |
| 96 | S | A | -1.3508 | Soluble |
| 97 | E | A | -1.9518 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | S | A | -0.7971 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.3863 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | T | A | 1.0679 | Aggregation-prone |
| 109 | Y | A | 1.9889 | Aggregation-prone |
| 110 | Y | A | 1.7371 | Aggregation-prone |
| 111 | G | A | 0.2767 | Aggregation-prone |
| 112A | G | A | 0.3427 | Aggregation-prone |
| 112 | D | A | 0.0000 | Buried |
| 113 | W | A | 1.3414 | Aggregation-prone |
| 114 | Y | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | N | A | -0.1406 | Soluble |
| 117 | V | A | -0.2882 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | A | A | -0.3859 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | C | A | -0.1767 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.7468 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.6358 | Soluble |
| 128 | A | A | -0.4102 | Soluble |
| 129 | A | A | -0.2809 | Soluble |
| 130 | S | A | -0.5048 | Soluble |
| 131 | T | A | -0.6174 | Soluble |
| 132 | K | A | -0.9626 | Soluble |
| 133 | G | A | -1.1944 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3159 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | 0.0000 | Buried |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.5752 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.2816 | Soluble |
| 143 | S | A | -0.3314 | Soluble |
| 144 | K | A | -0.4172 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.4961 | Soluble |
| 147 | S | A | -0.5785 | Soluble |
| 148 | G | A | -0.7985 | Soluble |
| 149 | G | A | -0.8816 | Soluble |
| 150 | T | A | -0.6263 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.2155 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | -0.4329 | Soluble |
| 162 | C | A | 0.0000 | Buried |
| 163 | E | A | -1.2436 | Soluble |
| 164 | C | A | 0.0000 | Buried |
| 165 | P | A | -0.9777 | Soluble |
| 166 | V | A | 0.0000 | Buried |
| 167 | T | A | -0.6627 | Soluble |
| 168 | V | A | -0.3987 | Soluble |
| 169 | S | A | -0.3718 | Soluble |
| 170 | W | A | 0.0000 | Buried |
| 171 | N | A | -0.6824 | Soluble |
| 172 | S | A | -0.5993 | Soluble |
| 173 | G | A | -0.4698 | Soluble |
| 174 | A | A | -0.2272 | Soluble |
| 175 | L | A | 0.0162 | Aggregation-prone |
| 176 | T | A | -0.1262 | Soluble |
| 177 | S | A | -0.1199 | Soluble |
| 178 | G | A | -0.0859 | Soluble |
| 179 | V | A | 0.2378 | Aggregation-prone |
| 180 | H | A | -0.0356 | Soluble |
| 181 | T | A | 0.0494 | Aggregation-prone |
| 182 | F | A | 0.0000 | Buried |
| 183 | P | A | -0.0065 | Soluble |
| 184 | A | A | 0.0089 | Aggregation-prone |
| 185 | V | A | 0.3785 | Aggregation-prone |
| 186 | L | A | 1.0243 | Aggregation-prone |
| 187 | Q | A | 0.2817 | Aggregation-prone |
| 188 | S | A | -0.0986 | Soluble |
| 189 | S | A | -0.1842 | Soluble |
| 190 | G | A | 0.1244 | Aggregation-prone |
| 191 | L | A | 0.0869 | Aggregation-prone |
| 192 | Y | A | 0.1805 | Aggregation-prone |
| 193 | S | A | 0.0000 | Buried |
| 194 | L | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | V | A | 0.0000 | Buried |
| 199 | T | A | -0.0854 | Soluble |
| 200 | V | A | 0.0000 | Buried |
| 201 | P | A | -0.5233 | Soluble |
| 202 | S | A | -0.5883 | Soluble |
| 203 | S | A | -0.5928 | Soluble |
| 204 | S | A | -0.5603 | Soluble |
| 205 | L | A | -0.8120 | Soluble |
| 206 | G | A | -1.0467 | Soluble |
| 207 | T | A | -0.6430 | Soluble |
| 208 | Q | A | -0.8995 | Soluble |
| 209 | T | A | -0.8983 | Soluble |
| 210 | Y | A | 0.0000 | Buried |
| 211 | I | A | -1.1089 | Soluble |
| 212 | C | A | 0.0000 | Buried |
| 213 | N | A | 0.0000 | Buried |
| 214 | V | A | 0.0000 | Buried |
| 215 | N | A | -2.0814 | Soluble |
| 216 | H | A | 0.0000 | Buried |
| 217 | K | A | -2.3170 | Soluble |
| 218 | P | A | -1.3261 | Soluble |
| 219 | S | A | -1.5776 | Soluble |
| 220 | N | A | -2.2970 | Soluble |
| 221 | T | A | -2.0575 | Soluble |
| 222 | K | A | -2.4258 | Soluble |
| 223 | V | A | -1.4860 | Soluble |
| 224 | D | A | -2.2773 | Soluble |
| 225 | K | A | -1.8037 | Soluble |
| 226 | K | A | -2.4436 | Soluble |
| 227 | V | A | 0.0000 | Buried |
| 228 | E | A | -1.5869 | Soluble |
| 229 | P | A | -0.9833 | Soluble |
| 230 | K | A | -1.9698 | Soluble |
| 231 | S | A | -1.1430 | Soluble |
| 232 | C | A | -0.2366 | Soluble |
| 1 | Q | B | -1.2122 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.9919 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | S | B | -0.6872 | Soluble |
| 6 | Q | B | -0.5169 | Soluble |
| 7 | S | B | -0.3901 | Soluble |
| 8 | P | B | 0.2964 | Aggregation-prone |
| 9 | A | B | 0.6085 | Aggregation-prone |
| 10 | I | B | 1.6500 | Aggregation-prone |
| 11 | L | B | 0.7692 | Aggregation-prone |
| 12 | S | B | -0.3500 | Soluble |
| 13 | A | B | 0.0000 | Buried |
| 14 | S | B | -1.9925 | Soluble |
| 15 | P | B | -2.1985 | Soluble |
| 16 | G | B | -2.4998 | Soluble |
| 17 | E | B | -3.3900 | Soluble |
| 18 | K | B | -3.1788 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.4797 | Soluble |
| 21 | M | B | 0.0000 | Buried |
| 22 | T | B | -0.6933 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.8834 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.3541 | Soluble |
| 27 | S | B | -0.5242 | Soluble |
| 28 | S | B | -0.7248 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 37 | S | B | -0.1956 | Soluble |
| 38 | Y | B | 0.1502 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | F | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -0.8655 | Soluble |
| 45 | K | B | -0.7949 | Soluble |
| 46 | C | B | 0.2550 | Aggregation-prone |
| 47 | G | B | -0.2995 | Soluble |
| 48 | S | B | -0.5556 | Soluble |
| 49 | S | B | -0.5410 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.8517 | Soluble |
| 52 | P | B | -0.9034 | Soluble |
| 53 | W | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.0988 | Aggregation-prone |
| 56 | A | B | 0.0000 | Buried |
| 57 | T | B | -0.2787 | Soluble |
| 65 | S | B | -0.5037 | Soluble |
| 66 | N | B | -0.4894 | Soluble |
| 67 | L | B | 0.1559 | Aggregation-prone |
| 68 | A | B | 0.0000 | Buried |
| 69 | S | B | -0.4948 | Soluble |
| 70 | G | B | -0.2784 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | 0.5697 | Aggregation-prone |
| 74 | V | B | 1.4617 | Aggregation-prone |
| 75 | R | B | -0.1321 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0184 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.5075 | Soluble |
| 80 | G | B | -0.6582 | Soluble |
| 83 | S | B | -0.6836 | Soluble |
| 84 | G | B | -0.7291 | Soluble |
| 85 | T | B | -0.9975 | Soluble |
| 86 | S | B | -1.1106 | Soluble |
| 87 | Y | B | 0.0000 | Buried |
| 88 | S | B | -0.5775 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.7800 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.0430 | Soluble |
| 93 | R | B | -3.5206 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -3.0349 | Soluble |
| 96 | C | B | -2.3289 | Soluble |
| 97 | E | B | -2.5822 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | A | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.2520 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | W | B | -0.1168 | Soluble |
| 108 | T | B | -0.3899 | Soluble |
| 109 | S | B | -1.0325 | Soluble |
| 114 | N | B | -1.7597 | Soluble |
| 115 | P | B | 0.0000 | Buried |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.2168 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.7797 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.3062 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -0.6904 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.3907 | Soluble |
| 128 | R | B | -0.8748 | Soluble |
| 129 | T | B | 0.2556 | Aggregation-prone |
| 130 | V | B | 1.0247 | Aggregation-prone |
| 131 | A | B | 0.4335 | Aggregation-prone |
| 132 | A | B | -0.0063 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2418 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.3601 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.2405 | Soluble |
| 142 | D | B | -2.5117 | Soluble |
| 143 | E | B | -2.1664 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.0402 | Soluble |
| 146 | K | B | -2.5916 | Soluble |
| 147 | S | B | -1.5991 | Soluble |
| 148 | G | B | -1.3268 | Soluble |
| 149 | T | B | -1.1504 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.6399 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.1788 | Soluble |
| 162 | R | B | -2.0060 | Soluble |
| 163 | E | B | -2.9358 | Soluble |
| 164 | A | B | -2.2289 | Soluble |
| 165 | K | B | -2.4436 | Soluble |
| 166 | V | B | -1.0914 | Soluble |
| 167 | Q | B | -0.5683 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5533 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8388 | Soluble |
| 172 | N | B | -1.3542 | Soluble |
| 173 | A | B | -0.2839 | Soluble |
| 174 | L | B | 0.7638 | Aggregation-prone |
| 175 | Q | B | -0.0784 | Soluble |
| 176 | S | B | -0.4479 | Soluble |
| 177 | G | B | -0.8988 | Soluble |
| 178 | N | B | -0.8362 | Soluble |
| 179 | S | B | -0.9577 | Soluble |
| 180 | Q | B | -1.0827 | Soluble |
| 181 | E | B | -1.4882 | Soluble |
| 182 | S | B | -0.5365 | Soluble |
| 183 | V | B | -0.0883 | Soluble |
| 184 | T | B | 0.1447 | Aggregation-prone |
| 185 | C | B | 0.2585 | Aggregation-prone |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -1.2471 | Soluble |
| 188 | S | B | -2.0134 | Soluble |
| 189 | K | B | -2.6831 | Soluble |
| 190 | D | B | -2.0648 | Soluble |
| 191 | C | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.4666 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4664 | Soluble |
| 201 | L | B | -0.7685 | Soluble |
| 202 | S | B | -1.3850 | Soluble |
| 203 | K | B | -2.1970 | Soluble |
| 204 | A | B | -2.0627 | Soluble |
| 205 | D | B | -2.9013 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.5495 | Soluble |
| 208 | K | B | -3.6887 | Soluble |
| 209 | H | B | -3.1246 | Soluble |
| 210 | K | B | -2.7639 | Soluble |
| 211 | V | B | -1.4011 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7019 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1401 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.3769 | Soluble |
| 220 | G | B | -0.2982 | Soluble |
| 221 | L | B | -0.1857 | Soluble |
| 222 | S | B | -0.4528 | Soluble |
| 223 | S | B | -0.3810 | Soluble |
| 224 | P | B | -0.4636 | Soluble |
| 225 | V | B | 0.2260 | Aggregation-prone |
| 226 | T | B | -0.2389 | Soluble |
| 227 | K | B | -0.4071 | Soluble |
| 228 | S | B | -0.5088 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.8209 | Soluble |
| 231 | R | B | -2.2259 | Soluble |
| 232 | G | B | -1.7894 | Soluble |
| 233 | E | B | -1.8552 | Soluble |
| 234 | C | B | -0.4226 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6238 | 2.773 | CSV PDB |
| 4.5 | -0.657 | 2.773 | CSV PDB |
| 5.0 | -0.6948 | 2.773 | CSV PDB |
| 5.5 | -0.7283 | 2.773 | CSV PDB |
| 6.0 | -0.7469 | 2.773 | CSV PDB |
| 6.5 | -0.742 | 2.773 | CSV PDB |
| 7.0 | -0.7142 | 2.7729 | CSV PDB |
| 7.5 | -0.6722 | 2.7727 | CSV PDB |
| 8.0 | -0.6231 | 2.7867 | CSV PDB |
| 8.5 | -0.5693 | 2.8906 | CSV PDB |
| 9.0 | -0.5115 | 2.9951 | CSV PDB |