Calculation Parameters
| Chain Sequence(s) |
EVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKDILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.2257 | Soluble |
| 2 | V | A | -1.3939 | Soluble |
| 3 | K | A | -2.4412 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | E | A | -2.2337 | Soluble |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -1.0570 | Soluble |
| 8 | G | A | -1.1003 | Soluble |
| 9 | G | A | -0.8243 | Soluble |
| 11 | G | A | -0.7107 | Soluble |
| 12 | L | A | -0.4608 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.8651 | Soluble |
| 15 | P | A | -2.0009 | Soluble |
| 16 | G | A | -2.0431 | Soluble |
| 17 | G | A | -1.4995 | Soluble |
| 18 | S | A | -1.3875 | Soluble |
| 19 | M | A | -1.1917 | Soluble |
| 20 | K | A | -1.7521 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.6724 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | V | A | -0.5005 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0266 | Soluble |
| 27 | G | A | -0.9076 | Soluble |
| 28 | F | A | 0.3578 | Aggregation-prone |
| 29 | I | A | 1.5726 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.9211 | Soluble |
| 36 | N | A | -0.9123 | Soluble |
| 37 | H | A | -0.1602 | Soluble |
| 38 | W | A | -0.1616 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7874 | Soluble |
| 45 | S | A | -1.5397 | Soluble |
| 46 | P | A | -1.6835 | Soluble |
| 47 | E | A | -3.1003 | Soluble |
| 48 | K | A | -3.0648 | Soluble |
| 49 | G | A | -1.6923 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6390 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | E | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | R | A | -0.7667 | Soluble |
| 58 | S | A | 0.0000 | Buried |
| 59 | K | A | -2.1800 | Soluble |
| 60 | S | A | -0.9826 | Soluble |
| 61 | I | A | 0.0104 | Aggregation-prone |
| 62 | N | A | -1.3129 | Soluble |
| 63 | S | A | -1.1775 | Soluble |
| 64 | A | A | -0.5885 | Soluble |
| 65 | T | A | -0.4287 | Soluble |
| 66 | H | A | -0.8251 | Soluble |
| 67 | Y | A | -1.1329 | Soluble |
| 68 | A | A | -1.3915 | Soluble |
| 69 | E | A | -2.5180 | Soluble |
| 70 | S | A | -1.5087 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5826 | Soluble |
| 74 | G | A | -1.7613 | Soluble |
| 75 | R | A | 0.0000 | Buried |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.7209 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.3678 | Soluble |
| 80 | R | A | -0.9267 | Soluble |
| 81 | D | A | -1.2036 | Soluble |
| 82 | D | A | -1.4165 | Soluble |
| 83 | S | A | -1.4034 | Soluble |
| 84 | K | A | -1.9681 | Soluble |
| 85 | S | A | -0.7125 | Soluble |
| 86 | A | A | 0.0000 | Buried |
| 87 | V | A | 0.0000 | Buried |
| 88 | Y | A | -0.2742 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -0.9805 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | T | A | -1.5750 | Soluble |
| 93 | D | A | -2.5410 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.5547 | Soluble |
| 96 | T | A | -1.8103 | Soluble |
| 97 | E | A | -2.7044 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9825 | Soluble |
| 100 | G | A | 0.0000 | Buried |
| 101 | V | A | 0.2154 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | N | A | 0.0000 | Buried |
| 108 | Y | A | 1.2796 | Aggregation-prone |
| 109 | Y | A | 0.9327 | Aggregation-prone |
| 110 | G | A | 0.4754 | Aggregation-prone |
| 113 | S | A | 0.0000 | Buried |
| 114 | T | A | 0.0000 | Buried |
| 115 | Y | A | 0.0000 | Buried |
| 116 | D | A | 0.0930 | Aggregation-prone |
| 117 | Y | A | 0.2880 | Aggregation-prone |
| 118 | W | A | -0.5710 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.9598 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | -0.5851 | Soluble |
| 123 | T | A | -0.2089 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | T | A | -0.6040 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0133 | Soluble |
| 128 | S | A | -0.7629 | Soluble |
| 129 | A | A | -0.5155 | Soluble |
| 130 | S | A | -0.6155 | Soluble |
| 131 | T | A | -0.7643 | Soluble |
| 132 | K | A | -1.1988 | Soluble |
| 133 | G | A | -1.3188 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.2941 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.5063 | Soluble |
| 138 | P | A | -0.9057 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2253 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.9948 | Soluble |
| 143 | S | A | -0.6992 | Soluble |
| 144 | K | A | -0.7263 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.5038 | Soluble |
| 147 | S | A | -0.5749 | Soluble |
| 148 | G | A | -0.8149 | Soluble |
| 149 | G | A | -0.8672 | Soluble |
| 150 | T | A | -0.5865 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.2976 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.5107 | Soluble |
| 164 | P | A | -0.6926 | Soluble |
| 165 | V | A | -0.5700 | Soluble |
| 166 | T | A | -0.4695 | Soluble |
| 167 | V | A | -0.2970 | Soluble |
| 168 | S | A | -0.3588 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.7338 | Soluble |
| 171 | S | A | -0.6655 | Soluble |
| 172 | G | A | -0.5124 | Soluble |
| 173 | A | A | -0.2317 | Soluble |
| 174 | L | A | 0.0357 | Aggregation-prone |
| 175 | T | A | -0.1507 | Soluble |
| 176 | S | A | -0.1517 | Soluble |
| 177 | G | A | -0.1653 | Soluble |
| 178 | V | A | 0.1842 | Aggregation-prone |
| 179 | H | A | -0.2892 | Soluble |
| 180 | T | A | 0.0375 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.1907 | Soluble |
| 183 | A | A | 0.3735 | Aggregation-prone |
| 184 | V | A | 0.8172 | Aggregation-prone |
| 185 | L | A | 1.5188 | Aggregation-prone |
| 186 | Q | A | 0.4926 | Aggregation-prone |
| 187 | S | A | 0.0001 | Aggregation-prone |
| 188 | S | A | -0.1790 | Soluble |
| 189 | G | A | 0.0793 | Aggregation-prone |
| 190 | L | A | 0.1957 | Aggregation-prone |
| 191 | Y | A | 0.5685 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1802 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5310 | Soluble |
| 201 | S | A | -0.5706 | Soluble |
| 202 | S | A | -0.5566 | Soluble |
| 203 | S | A | -0.5580 | Soluble |
| 204 | L | A | -0.8886 | Soluble |
| 205 | G | A | -1.2694 | Soluble |
| 206 | T | A | -0.7242 | Soluble |
| 207 | Q | A | -1.2819 | Soluble |
| 208 | T | A | -1.0841 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.1101 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4176 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.7457 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7076 | Soluble |
| 217 | P | A | -1.5725 | Soluble |
| 218 | S | A | -1.7878 | Soluble |
| 219 | N | A | -2.5443 | Soluble |
| 220 | T | A | -1.9911 | Soluble |
| 221 | K | A | -2.6144 | Soluble |
| 222 | V | A | -1.7153 | Soluble |
| 223 | D | A | -2.4827 | Soluble |
| 224 | K | A | -1.9104 | Soluble |
| 225 | K | A | -2.2820 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.7648 | Soluble |
| 228 | P | A | -1.8701 | Soluble |
| 229 | K | A | -2.4756 | Soluble |
| 1 | D | B | -1.4046 | Soluble |
| 2 | I | B | -0.0493 | Soluble |
| 3 | L | B | 0.6341 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5803 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.2834 | Soluble |
| 8 | P | B | 0.2874 | Aggregation-prone |
| 9 | A | B | 0.6340 | Aggregation-prone |
| 10 | I | B | 1.7006 | Aggregation-prone |
| 11 | L | B | 0.8637 | Aggregation-prone |
| 12 | S | B | 0.1454 | Aggregation-prone |
| 13 | V | B | -1.1180 | Soluble |
| 14 | S | B | -1.5993 | Soluble |
| 15 | P | B | -1.9137 | Soluble |
| 16 | G | B | -2.1904 | Soluble |
| 17 | E | B | -3.0202 | Soluble |
| 18 | R | B | -3.3078 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | S | B | -0.7415 | Soluble |
| 21 | F | B | 0.0000 | Buried |
| 22 | S | B | -0.9503 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2959 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.6556 | Soluble |
| 27 | Q | B | -0.7735 | Soluble |
| 28 | F | B | 0.7032 | Aggregation-prone |
| 29 | V | B | 0.0000 | Buried |
| 36 | G | B | -0.0268 | Soluble |
| 37 | S | B | -0.1150 | Soluble |
| 38 | S | B | 0.0000 | Buried |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | R | B | -1.9787 | Soluble |
| 46 | T | B | -1.7071 | Soluble |
| 47 | N | B | -1.9650 | Soluble |
| 48 | G | B | -1.4792 | Soluble |
| 49 | S | B | -1.0346 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -0.8460 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | K | B | -0.6836 | Soluble |
| 56 | Y | B | 0.0051 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -1.1374 | Soluble |
| 66 | E | B | -1.9061 | Soluble |
| 67 | S | B | -1.0961 | Soluble |
| 68 | M | B | -0.6290 | Soluble |
| 69 | S | B | -0.5445 | Soluble |
| 70 | G | B | -0.4786 | Soluble |
| 71 | I | B | -0.2843 | Soluble |
| 72 | P | B | -0.3382 | Soluble |
| 74 | S | B | -0.6309 | Soluble |
| 75 | R | B | -1.2380 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9784 | Soluble |
| 78 | G | B | -0.7135 | Soluble |
| 79 | S | B | -0.8317 | Soluble |
| 80 | G | B | -1.0510 | Soluble |
| 83 | S | B | -0.6875 | Soluble |
| 84 | G | B | -0.4628 | Soluble |
| 85 | T | B | -1.1972 | Soluble |
| 86 | D | B | -2.3149 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8821 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | S | B | -0.9797 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | N | B | -2.6030 | Soluble |
| 93 | T | B | -2.4103 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.7005 | Soluble |
| 96 | S | B | -2.2228 | Soluble |
| 97 | E | B | -2.3063 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | I | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | D | B | -0.7611 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | -0.1804 | Soluble |
| 108 | H | B | -0.4588 | Soluble |
| 109 | S | B | -0.3871 | Soluble |
| 114 | W | B | 0.0609 | Aggregation-prone |
| 115 | P | B | -0.4514 | Soluble |
| 116 | F | B | 0.0000 | Buried |
| 117 | T | B | 0.0634 | Aggregation-prone |
| 118 | F | B | 0.3532 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | S | B | -0.7357 | Soluble |
| 121 | G | B | -0.2120 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | N | B | -0.2049 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -0.5771 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | K | B | -1.3911 | Soluble |
| 128 | R | B | -0.9864 | Soluble |
| 129 | T | B | -0.0328 | Soluble |
| 130 | V | B | 0.4715 | Aggregation-prone |
| 131 | A | B | 0.0126 | Aggregation-prone |
| 132 | A | B | -0.0937 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2101 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.7531 | Soluble |
| 140 | P | B | -0.6775 | Soluble |
| 141 | S | B | -1.5117 | Soluble |
| 142 | D | B | -2.5636 | Soluble |
| 143 | E | B | -2.2667 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.8327 | Soluble |
| 146 | K | B | -2.5940 | Soluble |
| 147 | S | B | -1.6078 | Soluble |
| 148 | G | B | -1.1695 | Soluble |
| 149 | T | B | -1.0857 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.3175 | Soluble |
| 158 | N | B | -0.8577 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5903 | Soluble |
| 162 | R | B | -2.8181 | Soluble |
| 163 | E | B | -3.0992 | Soluble |
| 164 | A | B | -2.2923 | Soluble |
| 165 | K | B | -2.5687 | Soluble |
| 166 | V | B | 0.0000 | Buried |
| 167 | Q | B | -0.9467 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.9060 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -2.0356 | Soluble |
| 172 | N | B | -1.7217 | Soluble |
| 173 | A | B | -0.5634 | Soluble |
| 174 | L | B | 0.0731 | Aggregation-prone |
| 175 | Q | B | -0.6063 | Soluble |
| 176 | S | B | -0.8246 | Soluble |
| 177 | G | B | -1.2253 | Soluble |
| 178 | N | B | -1.5435 | Soluble |
| 179 | S | B | -1.3118 | Soluble |
| 180 | Q | B | -0.9877 | Soluble |
| 181 | E | B | -1.2711 | Soluble |
| 182 | S | B | -0.5686 | Soluble |
| 183 | V | B | -0.5549 | Soluble |
| 184 | T | B | -1.0094 | Soluble |
| 185 | E | B | -2.3189 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.1380 | Soluble |
| 188 | S | B | -2.3298 | Soluble |
| 189 | K | B | -2.6055 | Soluble |
| 190 | D | B | -1.9035 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | 0.0000 | Buried |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.7409 | Soluble |
| 201 | L | B | 0.0000 | Buried |
| 202 | S | B | -1.3553 | Soluble |
| 203 | K | B | -2.3557 | Soluble |
| 204 | A | B | -2.2221 | Soluble |
| 205 | D | B | -3.2348 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.9849 | Soluble |
| 208 | K | B | -3.9305 | Soluble |
| 209 | H | B | -3.3404 | Soluble |
| 210 | K | B | -3.1837 | Soluble |
| 211 | V | B | -1.5228 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.8520 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2559 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7402 | Soluble |
| 220 | G | B | -0.4215 | Soluble |
| 221 | L | B | -0.2317 | Soluble |
| 222 | S | B | -0.4693 | Soluble |
| 223 | S | B | -0.4328 | Soluble |
| 224 | P | B | -0.5841 | Soluble |
| 225 | V | B | 0.0052 | Aggregation-prone |
| 226 | T | B | -0.4064 | Soluble |
| 227 | K | B | -0.5180 | Soluble |
| 228 | S | B | -0.5497 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -2.0940 | Soluble |
| 231 | R | B | -2.6474 | Soluble |
| 232 | G | B | -2.2511 | Soluble |
| 233 | E | B | -2.5529 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7012 | 3.2485 | CSV PDB |
| 4.5 | -0.7498 | 3.229 | CSV PDB |
| 5.0 | -0.8084 | 3.206 | CSV PDB |
| 5.5 | -0.8648 | 3.1819 | CSV PDB |
| 6.0 | -0.9053 | 3.1585 | CSV PDB |
| 6.5 | -0.9197 | 3.1375 | CSV PDB |
| 7.0 | -0.9077 | 3.1192 | CSV PDB |
| 7.5 | -0.8785 | 3.1031 | CSV PDB |
| 8.0 | -0.8401 | 3.0886 | CSV PDB |
| 8.5 | -0.7956 | 3.0762 | CSV PDB |
| 9.0 | -0.7454 | 3.0674 | CSV PDB |