Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNFNDYFMNWVRQAPGKGLEWVAQMRNKNYQYGTYYAESLEGRFTISRDDSKNSLYLQMNSLKTEDTAVYYCARESYYGFTSYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESDIQMTQSPSSLSASVGDRVTITCQASQDIGISLSWYQQKPGKAPKLLIYNANNLADGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCLQHNSAPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1827 | Soluble |
| 2 | V | A | -1.4999 | Soluble |
| 3 | Q | A | -1.3414 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.0356 | Aggregation-prone |
| 6 | E | A | 0.2106 | Aggregation-prone |
| 7 | S | A | -0.3926 | Soluble |
| 8 | G | A | -0.9947 | Soluble |
| 9 | G | A | -0.5951 | Soluble |
| 11 | G | A | -0.0224 | Soluble |
| 12 | L | A | 0.0119 | Aggregation-prone |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.6522 | Soluble |
| 15 | P | A | -1.7550 | Soluble |
| 16 | G | A | -1.4505 | Soluble |
| 17 | G | A | 0.0000 | Buried |
| 18 | S | A | -1.3281 | Soluble |
| 19 | L | A | -1.2802 | Soluble |
| 20 | R | A | -2.2589 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.5037 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.1543 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.1097 | Soluble |
| 27 | G | A | -1.5241 | Soluble |
| 28 | F | A | -1.3744 | Soluble |
| 29 | N | A | -1.9488 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | N | A | -2.5204 | Soluble |
| 36 | D | A | -2.5492 | Soluble |
| 37 | Y | A | -0.9823 | Soluble |
| 38 | F | A | -0.0360 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7971 | Soluble |
| 45 | A | A | -1.2095 | Soluble |
| 46 | P | A | -0.9896 | Soluble |
| 47 | G | A | -1.5227 | Soluble |
| 48 | K | A | -2.3657 | Soluble |
| 49 | G | A | -1.8374 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.0646 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | Q | A | 0.0000 | Buried |
| 56 | M | A | 0.0000 | Buried |
| 57 | R | A | -0.8471 | Soluble |
| 58 | N | A | -1.8038 | Soluble |
| 59 | K | A | -2.7765 | Soluble |
| 60 | N | A | -2.3094 | Soluble |
| 61 | Y | A | -0.8257 | Soluble |
| 62 | Q | A | -1.6546 | Soluble |
| 63 | Y | A | -0.8148 | Soluble |
| 64 | G | A | -0.4113 | Soluble |
| 65 | T | A | 0.2326 | Aggregation-prone |
| 66 | Y | A | 0.3122 | Aggregation-prone |
| 67 | Y | A | -0.5436 | Soluble |
| 68 | A | A | -1.4564 | Soluble |
| 69 | E | A | -2.7963 | Soluble |
| 70 | S | A | -1.7915 | Soluble |
| 71 | L | A | 0.0000 | Buried |
| 72 | E | A | -2.7158 | Soluble |
| 74 | G | A | -1.8171 | Soluble |
| 75 | R | A | -1.5387 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.6031 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.3573 | Soluble |
| 80 | R | A | -0.8717 | Soluble |
| 81 | D | A | -1.4645 | Soluble |
| 82 | D | A | -2.2206 | Soluble |
| 83 | S | A | -1.5964 | Soluble |
| 84 | K | A | -2.3876 | Soluble |
| 85 | N | A | -2.0049 | Soluble |
| 86 | S | A | 0.0000 | Buried |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.7037 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.5546 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.3751 | Soluble |
| 93 | S | A | -1.1890 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | K | A | -2.5069 | Soluble |
| 96 | T | A | -1.9386 | Soluble |
| 97 | E | A | -2.3354 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7794 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1498 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.1609 | Aggregation-prone |
| 107 | E | A | 0.0000 | Buried |
| 108 | S | A | 1.2216 | Aggregation-prone |
| 109 | Y | A | 1.8285 | Aggregation-prone |
| 110 | Y | A | 1.8478 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | F | A | 0.0000 | Buried |
| 115 | T | A | 0.0000 | Buried |
| 116 | S | A | 0.3347 | Aggregation-prone |
| 117 | Y | A | 0.1944 | Aggregation-prone |
| 118 | W | A | -0.0860 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3571 | Soluble |
| 121 | G | A | -0.5190 | Soluble |
| 122 | T | A | -0.0644 | Soluble |
| 123 | L | A | 0.2170 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0222 | Soluble |
| 128 | S | A | -0.7302 | Soluble |
| 129 | A | A | -0.5667 | Soluble |
| 130 | S | A | -0.6837 | Soluble |
| 131 | T | A | -0.7815 | Soluble |
| 132 | K | A | -1.6008 | Soluble |
| 133 | G | A | -1.6498 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.5109 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2249 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.6206 | Soluble |
| 141 | P | A | -0.6203 | Soluble |
| 142 | C | A | -0.7631 | Soluble |
| 143 | S | A | -1.2637 | Soluble |
| 144 | R | A | -2.2491 | Soluble |
| 145 | S | A | -1.7012 | Soluble |
| 146 | T | A | -1.2021 | Soluble |
| 147 | S | A | -1.2648 | Soluble |
| 148 | E | A | -1.9735 | Soluble |
| 149 | S | A | -1.1133 | Soluble |
| 150 | T | A | -0.7594 | Soluble |
| 151 | A | A | -0.7574 | Soluble |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5550 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.4395 | Soluble |
| 164 | P | A | -0.7816 | Soluble |
| 165 | V | A | -0.8338 | Soluble |
| 166 | T | A | -0.7536 | Soluble |
| 167 | V | A | -0.3202 | Soluble |
| 168 | S | A | -0.6034 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -1.1707 | Soluble |
| 171 | S | A | -0.8537 | Soluble |
| 172 | G | A | -0.6431 | Soluble |
| 173 | A | A | -0.3106 | Soluble |
| 174 | L | A | -0.1221 | Soluble |
| 175 | T | A | -0.2123 | Soluble |
| 176 | S | A | -0.2074 | Soluble |
| 177 | G | A | -0.2612 | Soluble |
| 178 | V | A | 0.1389 | Aggregation-prone |
| 179 | H | A | -0.3171 | Soluble |
| 180 | T | A | 0.0241 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.4917 | Soluble |
| 183 | A | A | 0.1180 | Aggregation-prone |
| 184 | V | A | 0.3211 | Aggregation-prone |
| 185 | L | A | 0.9809 | Aggregation-prone |
| 186 | Q | A | 0.2202 | Aggregation-prone |
| 187 | S | A | -0.0752 | Soluble |
| 188 | S | A | -0.2060 | Soluble |
| 189 | G | A | 0.0043 | Aggregation-prone |
| 190 | L | A | -0.0274 | Soluble |
| 191 | Y | A | 0.2801 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1252 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5699 | Soluble |
| 201 | S | A | -1.0149 | Soluble |
| 202 | S | A | -0.5627 | Soluble |
| 203 | S | A | -0.7019 | Soluble |
| 204 | L | A | -1.1602 | Soluble |
| 205 | G | A | -1.3033 | Soluble |
| 206 | T | A | -1.1274 | Soluble |
| 207 | K | A | -2.0582 | Soluble |
| 208 | T | A | -1.7738 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | T | A | 0.0000 | Buried |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.8269 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | D | A | -2.4208 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.8960 | Soluble |
| 217 | P | A | -1.7230 | Soluble |
| 218 | S | A | -1.9966 | Soluble |
| 219 | N | A | -2.7692 | Soluble |
| 220 | T | A | -2.2855 | Soluble |
| 221 | K | A | -2.8703 | Soluble |
| 222 | V | A | -1.8671 | Soluble |
| 223 | D | A | -2.8332 | Soluble |
| 224 | K | A | -2.3005 | Soluble |
| 225 | R | A | -2.9520 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.5921 | Soluble |
| 228 | S | A | -1.6483 | Soluble |
| 1 | D | B | -2.5864 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.0722 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.2268 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6258 | Soluble |
| 8 | P | B | -0.6993 | Soluble |
| 9 | S | B | -1.0264 | Soluble |
| 10 | S | B | -0.9681 | Soluble |
| 11 | L | B | -0.6063 | Soluble |
| 12 | S | B | -0.8328 | Soluble |
| 13 | A | B | 0.0000 | Buried |
| 14 | S | B | -1.0718 | Soluble |
| 15 | V | B | -0.4582 | Soluble |
| 16 | G | B | -1.2586 | Soluble |
| 17 | D | B | -2.2997 | Soluble |
| 18 | R | B | -2.6057 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.4847 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.7470 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | Q | B | -2.3109 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.2060 | Soluble |
| 27 | Q | B | -2.8425 | Soluble |
| 28 | D | B | -2.8256 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | G | B | -0.9015 | Soluble |
| 37 | I | B | 0.0807 | Aggregation-prone |
| 38 | S | B | 0.0193 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.7371 | Soluble |
| 46 | P | B | -1.6559 | Soluble |
| 47 | G | B | -1.7106 | Soluble |
| 48 | K | B | -2.6305 | Soluble |
| 49 | A | B | -1.6218 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.4788 | Soluble |
| 52 | L | B | -0.4465 | Soluble |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.2756 | Aggregation-prone |
| 56 | N | B | 0.0160 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | N | B | -1.3333 | Soluble |
| 66 | N | B | -1.0244 | Soluble |
| 67 | L | B | -0.4686 | Soluble |
| 68 | A | B | -0.9942 | Soluble |
| 69 | D | B | -1.8680 | Soluble |
| 70 | G | B | -1.2069 | Soluble |
| 71 | V | B | -0.7578 | Soluble |
| 72 | P | B | -0.4956 | Soluble |
| 74 | S | B | -0.3704 | Soluble |
| 75 | R | B | -0.8102 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.6358 | Soluble |
| 78 | G | B | -0.8044 | Soluble |
| 79 | S | B | -0.9793 | Soluble |
| 80 | G | B | -0.9863 | Soluble |
| 83 | S | B | -0.9931 | Soluble |
| 84 | G | B | -1.6205 | Soluble |
| 85 | T | B | -2.1791 | Soluble |
| 86 | D | B | -2.5608 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8814 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.5879 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.4760 | Soluble |
| 93 | S | B | -1.5507 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.1501 | Soluble |
| 96 | P | B | -1.2975 | Soluble |
| 97 | E | B | -1.8619 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.7847 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.9563 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | L | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | N | B | -0.7258 | Soluble |
| 109 | S | B | -0.6978 | Soluble |
| 114 | A | B | -0.3467 | Soluble |
| 115 | P | B | -0.6444 | Soluble |
| 116 | Y | B | 0.0000 | Buried |
| 117 | T | B | -0.9270 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8285 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.9560 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -1.1109 | Soluble |
| 126 | I | B | -0.6969 | Soluble |
| 127 | K | B | -1.2369 | Soluble |
| 128 | R | B | -0.9295 | Soluble |
| 129 | T | B | -0.0818 | Soluble |
| 130 | V | B | 0.4793 | Aggregation-prone |
| 131 | A | B | 0.0788 | Aggregation-prone |
| 132 | A | B | -0.0507 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.0569 | Soluble |
| 135 | V | B | 0.0318 | Aggregation-prone |
| 136 | F | B | 0.0396 | Aggregation-prone |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | 0.0000 | Buried |
| 140 | P | B | -0.6691 | Soluble |
| 141 | S | B | -1.4723 | Soluble |
| 142 | D | B | -2.7856 | Soluble |
| 143 | E | B | -2.8408 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1806 | Soluble |
| 146 | K | B | -2.7748 | Soluble |
| 147 | S | B | -1.7063 | Soluble |
| 148 | G | B | -1.1989 | Soluble |
| 149 | T | B | -0.8187 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.7999 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.4098 | Soluble |
| 162 | R | B | -2.3516 | Soluble |
| 163 | E | B | -2.8944 | Soluble |
| 164 | A | B | -2.1617 | Soluble |
| 165 | K | B | -2.3336 | Soluble |
| 166 | V | B | -1.0443 | Soluble |
| 167 | Q | B | -0.4753 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.4586 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8248 | Soluble |
| 172 | N | B | -1.4624 | Soluble |
| 173 | A | B | -0.1908 | Soluble |
| 174 | L | B | 0.8250 | Aggregation-prone |
| 175 | Q | B | -0.0459 | Soluble |
| 176 | S | B | -0.3762 | Soluble |
| 177 | G | B | -0.8805 | Soluble |
| 178 | N | B | -0.7770 | Soluble |
| 179 | S | B | -1.1129 | Soluble |
| 180 | Q | B | -1.4626 | Soluble |
| 181 | E | B | -1.9942 | Soluble |
| 182 | S | B | -0.8810 | Soluble |
| 183 | V | B | -0.7737 | Soluble |
| 184 | T | B | 0.0000 | Buried |
| 185 | E | B | -2.2304 | Soluble |
| 186 | Q | B | -1.8626 | Soluble |
| 187 | D | B | -1.9531 | Soluble |
| 188 | S | B | -1.9989 | Soluble |
| 189 | K | B | -2.3273 | Soluble |
| 190 | D | B | -1.8250 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6723 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4101 | Soluble |
| 201 | L | B | -0.5750 | Soluble |
| 202 | S | B | -0.9352 | Soluble |
| 203 | K | B | -1.8621 | Soluble |
| 204 | A | B | -1.6685 | Soluble |
| 205 | D | B | -2.2659 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.0615 | Soluble |
| 208 | K | B | -3.3761 | Soluble |
| 209 | H | B | -2.9367 | Soluble |
| 210 | K | B | -3.2397 | Soluble |
| 211 | V | B | -1.5133 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.8124 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7604 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2089 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6480 | Soluble |
| 220 | G | B | -0.3767 | Soluble |
| 221 | L | B | -0.2085 | Soluble |
| 222 | S | B | -0.4562 | Soluble |
| 223 | S | B | -0.4397 | Soluble |
| 224 | P | B | -0.5684 | Soluble |
| 225 | V | B | -0.0405 | Soluble |
| 226 | T | B | -0.4555 | Soluble |
| 227 | K | B | -0.7118 | Soluble |
| 228 | S | B | -0.6571 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.8127 | Soluble |
| 231 | R | B | -2.3206 | Soluble |
| 232 | G | B | -2.0088 | Soluble |
| 233 | E | B | -2.1916 | Soluble |
| 234 | C | B | -0.7498 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7599 | 2.1032 | CSV PDB |
| 4.5 | -0.8123 | 2.0655 | CSV PDB |
| 5.0 | -0.874 | 2.0222 | CSV PDB |
| 5.5 | -0.9341 | 1.9766 | CSV PDB |
| 6.0 | -0.9801 | 1.9311 | CSV PDB |
| 6.5 | -1.0017 | 1.931 | CSV PDB |
| 7.0 | -0.9981 | 1.9309 | CSV PDB |
| 7.5 | -0.9775 | 1.9304 | CSV PDB |
| 8.0 | -0.9472 | 1.9291 | CSV PDB |
| 8.5 | -0.9096 | 1.9247 | CSV PDB |
| 9.0 | -0.8643 | 1.9111 | CSV PDB |