Calculation Parameters
| Chain Sequence(s) |
EVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPDILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.0478 | Soluble |
| 2 | V | A | -1.0996 | Soluble |
| 3 | K | A | -1.6410 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | E | A | -1.8661 | Soluble |
| 6 | E | A | -1.1603 | Soluble |
| 7 | S | A | -1.0783 | Soluble |
| 8 | G | A | -1.1245 | Soluble |
| 9 | G | A | -0.7979 | Soluble |
| 11 | G | A | 0.0000 | Buried |
| 12 | L | A | -0.2684 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.8378 | Soluble |
| 15 | P | A | -1.9925 | Soluble |
| 16 | G | A | -2.0377 | Soluble |
| 17 | G | A | 0.0000 | Buried |
| 18 | S | A | -1.3779 | Soluble |
| 19 | M | A | -1.1350 | Soluble |
| 20 | K | A | -1.6283 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.6538 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | V | A | -0.1894 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.7220 | Soluble |
| 27 | G | A | -0.7449 | Soluble |
| 28 | F | A | 0.4425 | Aggregation-prone |
| 29 | I | A | 1.5612 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.7209 | Soluble |
| 36 | N | A | -0.8266 | Soluble |
| 37 | H | A | 0.0000 | Buried |
| 38 | W | A | -0.0436 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6607 | Soluble |
| 45 | S | A | 0.0000 | Buried |
| 46 | P | A | -1.4631 | Soluble |
| 47 | E | A | -2.7561 | Soluble |
| 48 | K | A | -2.3645 | Soluble |
| 49 | G | A | -1.3694 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5740 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | E | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | R | A | -0.7073 | Soluble |
| 58 | S | A | 0.0000 | Buried |
| 59 | K | A | -2.2334 | Soluble |
| 60 | S | A | -0.9926 | Soluble |
| 61 | I | A | -0.0273 | Soluble |
| 62 | N | A | -1.3166 | Soluble |
| 63 | S | A | -1.1787 | Soluble |
| 64 | A | A | -0.5904 | Soluble |
| 65 | T | A | -0.4077 | Soluble |
| 66 | H | A | -0.7888 | Soluble |
| 67 | Y | A | -1.1186 | Soluble |
| 68 | A | A | -1.4114 | Soluble |
| 69 | E | A | -2.5262 | Soluble |
| 70 | S | A | -1.5242 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5837 | Soluble |
| 74 | G | A | -1.7638 | Soluble |
| 75 | R | A | 0.0000 | Buried |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.8044 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.4320 | Soluble |
| 80 | R | A | -0.9508 | Soluble |
| 81 | D | A | -1.4200 | Soluble |
| 82 | D | A | -1.6669 | Soluble |
| 83 | S | A | -1.4745 | Soluble |
| 84 | K | A | -1.9929 | Soluble |
| 85 | S | A | -0.7277 | Soluble |
| 86 | A | A | 0.0000 | Buried |
| 87 | V | A | 0.0000 | Buried |
| 88 | Y | A | -0.3326 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.1832 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | T | A | -1.6020 | Soluble |
| 93 | D | A | -2.5254 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.5546 | Soluble |
| 96 | T | A | -1.8260 | Soluble |
| 97 | E | A | -2.5923 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7997 | Soluble |
| 100 | G | A | 0.0000 | Buried |
| 101 | V | A | 0.2158 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | N | A | 0.0000 | Buried |
| 108 | Y | A | 1.4301 | Aggregation-prone |
| 109 | Y | A | 1.1345 | Aggregation-prone |
| 110 | G | A | 0.5898 | Aggregation-prone |
| 113 | S | A | 0.0000 | Buried |
| 114 | T | A | 0.0000 | Buried |
| 115 | Y | A | 0.0000 | Buried |
| 116 | D | A | -0.0496 | Soluble |
| 117 | Y | A | 0.2442 | Aggregation-prone |
| 118 | W | A | -0.6293 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.9155 | Soluble |
| 121 | G | A | -1.0761 | Soluble |
| 122 | T | A | -0.6355 | Soluble |
| 123 | T | A | -0.1166 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | T | A | -0.5952 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0161 | Soluble |
| 128 | S | A | -0.7653 | Soluble |
| 129 | A | A | -0.5656 | Soluble |
| 130 | S | A | -0.7513 | Soluble |
| 131 | T | A | -0.8996 | Soluble |
| 132 | K | A | -1.8106 | Soluble |
| 133 | G | A | -1.7668 | Soluble |
| 134 | P | A | -0.8564 | Soluble |
| 135 | S | A | -0.5999 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1017 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8795 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.8089 | Soluble |
| 143 | S | A | -0.8480 | Soluble |
| 144 | K | A | -1.2970 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.7661 | Soluble |
| 147 | S | A | -0.7174 | Soluble |
| 148 | G | A | -0.8333 | Soluble |
| 149 | G | A | -0.8732 | Soluble |
| 150 | T | A | -0.6088 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | -0.3604 | Soluble |
| 159 | D | A | -0.6641 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.5545 | Soluble |
| 164 | P | A | -0.7176 | Soluble |
| 165 | V | A | -0.6601 | Soluble |
| 166 | T | A | -0.5490 | Soluble |
| 167 | V | A | -0.3100 | Soluble |
| 168 | S | A | -0.3392 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6471 | Soluble |
| 171 | S | A | -0.6115 | Soluble |
| 172 | G | A | -0.5183 | Soluble |
| 173 | A | A | -0.2386 | Soluble |
| 174 | L | A | 0.0187 | Aggregation-prone |
| 175 | T | A | -0.1664 | Soluble |
| 176 | S | A | -0.1740 | Soluble |
| 177 | G | A | -0.2030 | Soluble |
| 178 | V | A | 0.1710 | Aggregation-prone |
| 179 | H | A | -0.2633 | Soluble |
| 180 | T | A | 0.0362 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.2419 | Soluble |
| 183 | A | A | 0.2697 | Aggregation-prone |
| 184 | V | A | 0.5965 | Aggregation-prone |
| 185 | L | A | 1.1913 | Aggregation-prone |
| 186 | Q | A | 0.2659 | Aggregation-prone |
| 187 | S | A | -0.0571 | Soluble |
| 188 | S | A | -0.2269 | Soluble |
| 189 | G | A | -0.0013 | Soluble |
| 190 | L | A | 0.0045 | Aggregation-prone |
| 191 | Y | A | 0.3404 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1294 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5206 | Soluble |
| 201 | S | A | -0.5590 | Soluble |
| 202 | S | A | -0.5342 | Soluble |
| 203 | S | A | -0.5683 | Soluble |
| 204 | L | A | -0.7434 | Soluble |
| 205 | G | A | -1.1239 | Soluble |
| 206 | T | A | -0.8883 | Soluble |
| 207 | Q | A | -1.1913 | Soluble |
| 208 | T | A | -1.0827 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.0285 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.2595 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.8059 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7536 | Soluble |
| 217 | P | A | -1.6907 | Soluble |
| 218 | S | A | -1.9399 | Soluble |
| 219 | N | A | -2.5781 | Soluble |
| 220 | T | A | -2.1280 | Soluble |
| 221 | K | A | -2.5925 | Soluble |
| 222 | V | A | -1.4988 | Soluble |
| 223 | D | A | -1.9828 | Soluble |
| 224 | K | A | -1.7399 | Soluble |
| 225 | K | A | -2.1625 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.4503 | Soluble |
| 228 | P | A | -1.2211 | Soluble |
| 1 | D | B | -1.4984 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | L | B | 0.6091 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.4920 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.1947 | Soluble |
| 8 | P | B | 0.3664 | Aggregation-prone |
| 9 | A | B | 0.7053 | Aggregation-prone |
| 10 | I | B | 1.7610 | Aggregation-prone |
| 11 | L | B | 0.8682 | Aggregation-prone |
| 12 | S | B | 0.0735 | Aggregation-prone |
| 13 | V | B | -1.1748 | Soluble |
| 14 | S | B | -1.5866 | Soluble |
| 15 | P | B | -1.9246 | Soluble |
| 16 | G | B | -2.2083 | Soluble |
| 17 | E | B | -3.0071 | Soluble |
| 18 | R | B | -3.3743 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | S | B | -0.7424 | Soluble |
| 21 | F | B | 0.0000 | Buried |
| 22 | S | B | -0.9252 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.0111 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.6175 | Soluble |
| 27 | Q | B | -0.5849 | Soluble |
| 28 | F | B | 0.7217 | Aggregation-prone |
| 29 | V | B | 0.0000 | Buried |
| 36 | G | B | -0.0444 | Soluble |
| 37 | S | B | -0.1636 | Soluble |
| 38 | S | B | 0.0614 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.6638 | Soluble |
| 45 | R | B | -2.4284 | Soluble |
| 46 | T | B | -1.8488 | Soluble |
| 47 | N | B | -2.0590 | Soluble |
| 48 | G | B | -1.7660 | Soluble |
| 49 | S | B | -1.4233 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.9426 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | K | B | -0.7420 | Soluble |
| 56 | Y | B | -0.1176 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -1.1876 | Soluble |
| 66 | E | B | -1.9572 | Soluble |
| 67 | S | B | -1.1460 | Soluble |
| 68 | M | B | -0.6190 | Soluble |
| 69 | S | B | -0.5357 | Soluble |
| 70 | G | B | -0.4617 | Soluble |
| 71 | I | B | -0.3594 | Soluble |
| 72 | P | B | -0.3469 | Soluble |
| 74 | S | B | -0.6626 | Soluble |
| 75 | R | B | -1.2950 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9998 | Soluble |
| 78 | G | B | -0.7316 | Soluble |
| 79 | S | B | -0.8784 | Soluble |
| 80 | G | B | -1.1070 | Soluble |
| 83 | S | B | -0.7201 | Soluble |
| 84 | G | B | -0.4689 | Soluble |
| 85 | T | B | -1.2033 | Soluble |
| 86 | D | B | -2.3354 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8803 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | S | B | 0.0000 | Buried |
| 91 | I | B | 0.0000 | Buried |
| 92 | N | B | -2.7550 | Soluble |
| 93 | T | B | -2.4698 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.7077 | Soluble |
| 96 | S | B | -2.2894 | Soluble |
| 97 | E | B | -2.3262 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | I | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | D | B | -0.7778 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | -0.1514 | Soluble |
| 108 | H | B | -0.3496 | Soluble |
| 109 | S | B | -0.3380 | Soluble |
| 114 | W | B | 0.0663 | Aggregation-prone |
| 115 | P | B | -0.4664 | Soluble |
| 116 | F | B | 0.0000 | Buried |
| 117 | T | B | 0.0099 | Aggregation-prone |
| 118 | F | B | 0.2083 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | S | B | -0.5692 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | N | B | -0.0727 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -0.6401 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | K | B | -1.2879 | Soluble |
| 128 | R | B | -0.8671 | Soluble |
| 129 | T | B | 0.2722 | Aggregation-prone |
| 130 | V | B | 1.0296 | Aggregation-prone |
| 131 | A | B | 0.2555 | Aggregation-prone |
| 132 | A | B | 0.0507 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2275 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6978 | Soluble |
| 140 | P | B | -0.8331 | Soluble |
| 141 | S | B | -1.6011 | Soluble |
| 142 | D | B | -2.9458 | Soluble |
| 143 | E | B | -2.8802 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1981 | Soluble |
| 146 | K | B | -2.7942 | Soluble |
| 147 | S | B | -1.7460 | Soluble |
| 148 | G | B | -1.4409 | Soluble |
| 149 | T | B | -1.1596 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.9284 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5559 | Soluble |
| 162 | R | B | -3.0405 | Soluble |
| 163 | E | B | -3.2934 | Soluble |
| 164 | A | B | -2.3776 | Soluble |
| 165 | K | B | -2.5119 | Soluble |
| 166 | V | B | -1.2280 | Soluble |
| 167 | Q | B | -0.9248 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.8314 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8890 | Soluble |
| 172 | N | B | -1.5969 | Soluble |
| 173 | A | B | -0.4618 | Soluble |
| 174 | L | B | 0.2025 | Aggregation-prone |
| 175 | Q | B | -0.5954 | Soluble |
| 176 | S | B | -0.8906 | Soluble |
| 177 | G | B | -1.3024 | Soluble |
| 178 | N | B | -1.6891 | Soluble |
| 179 | S | B | -1.4897 | Soluble |
| 180 | Q | B | -1.3833 | Soluble |
| 181 | E | B | -1.5008 | Soluble |
| 182 | S | B | -0.7061 | Soluble |
| 183 | V | B | -0.4524 | Soluble |
| 184 | T | B | -1.0151 | Soluble |
| 185 | E | B | -2.3547 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.0978 | Soluble |
| 188 | S | B | -2.3750 | Soluble |
| 189 | K | B | -2.6817 | Soluble |
| 190 | D | B | -2.1295 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7456 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.8150 | Soluble |
| 201 | L | B | 0.0000 | Buried |
| 202 | S | B | -1.3138 | Soluble |
| 203 | K | B | -2.2599 | Soluble |
| 204 | A | B | -2.0904 | Soluble |
| 205 | D | B | -3.1419 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4760 | Soluble |
| 208 | K | B | -3.7245 | Soluble |
| 209 | H | B | -3.0908 | Soluble |
| 210 | K | B | -3.2441 | Soluble |
| 211 | V | B | -1.4409 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.9835 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2786 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6485 | Soluble |
| 220 | G | B | -0.2587 | Soluble |
| 221 | L | B | -0.1845 | Soluble |
| 222 | S | B | -0.4750 | Soluble |
| 223 | S | B | -0.4619 | Soluble |
| 224 | P | B | -0.4998 | Soluble |
| 225 | V | B | -0.1315 | Soluble |
| 226 | T | B | -0.5302 | Soluble |
| 227 | K | B | -0.8899 | Soluble |
| 228 | S | B | -0.7810 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -2.0221 | Soluble |
| 231 | R | B | -2.5645 | Soluble |
| 232 | G | B | -2.3731 | Soluble |
| 233 | E | B | -2.5262 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6941 | 3.2169 | CSV PDB |
| 4.5 | -0.7435 | 3.195 | CSV PDB |
| 5.0 | -0.8029 | 3.1682 | CSV PDB |
| 5.5 | -0.861 | 3.1396 | CSV PDB |
| 6.0 | -0.9042 | 3.1116 | CSV PDB |
| 6.5 | -0.922 | 3.0866 | CSV PDB |
| 7.0 | -0.9136 | 3.066 | CSV PDB |
| 7.5 | -0.8875 | 3.0491 | CSV PDB |
| 8.0 | -0.8517 | 3.0346 | CSV PDB |
| 8.5 | -0.8093 | 3.0229 | CSV PDB |
| 9.0 | -0.7609 | 3.0149 | CSV PDB |