Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMSWVRQAPGKGLEWVAYIKQDGNEKYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAREGILWFGDLPTFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQGISNWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYDSYPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | B (Heavy), E (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.0143 | Soluble |
| 2 | V | B | -1.0314 | Soluble |
| 3 | Q | B | -1.2524 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.2076 | Aggregation-prone |
| 6 | E | B | -0.2793 | Soluble |
| 7 | S | B | -0.5264 | Soluble |
| 8 | G | B | -0.9775 | Soluble |
| 9 | G | B | -0.6184 | Soluble |
| 11 | G | B | -0.1551 | Soluble |
| 12 | L | B | -0.1409 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.7018 | Soluble |
| 15 | P | B | -1.9106 | Soluble |
| 16 | G | B | -1.6775 | Soluble |
| 17 | G | B | -1.3561 | Soluble |
| 18 | S | B | -1.4362 | Soluble |
| 19 | L | B | -1.3813 | Soluble |
| 20 | R | B | -2.1477 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.5533 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.2886 | Soluble |
| 25 | A | B | -0.5971 | Soluble |
| 26 | S | B | -0.7790 | Soluble |
| 27 | G | B | -1.0263 | Soluble |
| 28 | F | B | -0.4332 | Soluble |
| 29 | T | B | -0.2579 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -1.1191 | Soluble |
| 36 | S | B | -0.2194 | Soluble |
| 37 | Y | B | 0.1320 | Aggregation-prone |
| 38 | W | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.8415 | Soluble |
| 45 | A | B | -1.2163 | Soluble |
| 46 | P | B | -1.2564 | Soluble |
| 47 | G | B | -1.7552 | Soluble |
| 48 | K | B | -2.3844 | Soluble |
| 49 | G | B | -1.6977 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.2262 | Soluble |
| 52 | W | B | -0.2583 | Soluble |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | Y | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | K | B | -1.9174 | Soluble |
| 58 | Q | B | -1.7813 | Soluble |
| 59 | D | B | -2.9082 | Soluble |
| 62 | G | B | -2.6223 | Soluble |
| 63 | N | B | -2.8810 | Soluble |
| 64 | E | B | -2.8100 | Soluble |
| 65 | K | B | -1.6960 | Soluble |
| 66 | Y | B | -0.7332 | Soluble |
| 67 | Y | B | -0.7971 | Soluble |
| 68 | V | B | 0.0000 | Buried |
| 69 | D | B | -2.3510 | Soluble |
| 70 | S | B | -1.7201 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.4773 | Soluble |
| 74 | G | B | -1.7952 | Soluble |
| 75 | R | B | -1.4837 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -0.9438 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.5388 | Soluble |
| 80 | R | B | -1.2065 | Soluble |
| 81 | D | B | -1.5761 | Soluble |
| 82 | N | B | -1.8043 | Soluble |
| 83 | A | B | -1.3426 | Soluble |
| 84 | K | B | -2.2502 | Soluble |
| 85 | N | B | -1.7198 | Soluble |
| 86 | S | B | 0.0000 | Buried |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | -0.5035 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.3508 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.1367 | Soluble |
| 93 | S | B | -1.6410 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.5873 | Soluble |
| 96 | A | B | -1.8384 | Soluble |
| 97 | E | B | -2.3055 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7118 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.0174 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.1794 | Aggregation-prone |
| 107 | E | B | 0.0000 | Buried |
| 108 | G | B | 0.0000 | Buried |
| 109 | I | B | 1.4291 | Aggregation-prone |
| 110 | L | B | 1.7206 | Aggregation-prone |
| 111 | W | B | 1.8140 | Aggregation-prone |
| 112A | F | B | 1.4586 | Aggregation-prone |
| 112 | G | B | 0.0000 | Buried |
| 113 | D | B | 0.2661 | Aggregation-prone |
| 114 | L | B | 0.6221 | Aggregation-prone |
| 115 | P | B | 0.2847 | Aggregation-prone |
| 116 | T | B | 0.0000 | Buried |
| 117 | F | B | 0.4813 | Aggregation-prone |
| 118 | W | B | -0.1502 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.4045 | Soluble |
| 121 | G | B | -0.6667 | Soluble |
| 122 | T | B | -0.1905 | Soluble |
| 123 | L | B | 0.1350 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.0202 | Soluble |
| 128 | S | B | -0.7523 | Soluble |
| 129 | A | B | -0.5667 | Soluble |
| 130 | S | B | -0.7082 | Soluble |
| 131 | T | B | -0.7650 | Soluble |
| 132 | K | B | -1.5894 | Soluble |
| 133 | G | B | -1.7793 | Soluble |
| 134 | P | B | -1.0276 | Soluble |
| 135 | S | B | -0.5625 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.0257 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.2330 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | 0.0000 | Buried |
| 143 | S | B | -0.7056 | Soluble |
| 144 | K | B | -0.7901 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.5290 | Soluble |
| 147 | S | B | -0.7400 | Soluble |
| 148 | G | B | -0.8527 | Soluble |
| 149 | G | B | -0.9124 | Soluble |
| 150 | T | B | -0.6023 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -1.0655 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.3648 | Soluble |
| 164 | P | B | -0.7554 | Soluble |
| 165 | V | B | -0.8855 | Soluble |
| 166 | T | B | -0.7903 | Soluble |
| 167 | V | B | -0.5155 | Soluble |
| 168 | S | B | -0.4098 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.6415 | Soluble |
| 171 | S | B | -0.5993 | Soluble |
| 172 | G | B | -0.5536 | Soluble |
| 173 | A | B | -0.2222 | Soluble |
| 174 | L | B | 0.0516 | Aggregation-prone |
| 175 | T | B | -0.1160 | Soluble |
| 176 | S | B | -0.1261 | Soluble |
| 177 | G | B | -0.0783 | Soluble |
| 178 | V | B | 0.2768 | Aggregation-prone |
| 179 | H | B | -0.2976 | Soluble |
| 180 | T | B | -0.1511 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.4962 | Soluble |
| 183 | A | B | 0.2759 | Aggregation-prone |
| 184 | V | B | 0.7346 | Aggregation-prone |
| 185 | L | B | 1.3815 | Aggregation-prone |
| 186 | Q | B | 0.2004 | Aggregation-prone |
| 187 | S | B | -0.2493 | Soluble |
| 188 | S | B | -0.3061 | Soluble |
| 189 | G | B | -0.0856 | Soluble |
| 190 | L | B | 0.0000 | Buried |
| 191 | Y | B | 0.2424 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.0885 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6029 | Soluble |
| 201 | S | B | -0.6052 | Soluble |
| 202 | S | B | -0.5763 | Soluble |
| 203 | S | B | 0.0000 | Buried |
| 204 | L | B | -0.8380 | Soluble |
| 205 | G | B | -0.9089 | Soluble |
| 206 | T | B | -0.6855 | Soluble |
| 207 | Q | B | -1.1352 | Soluble |
| 208 | T | B | -1.0948 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -0.9999 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4341 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.6743 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.9392 | Soluble |
| 217 | P | B | -1.7243 | Soluble |
| 218 | S | B | -2.0116 | Soluble |
| 219 | N | B | -2.8021 | Soluble |
| 220 | T | B | -2.3467 | Soluble |
| 221 | K | B | -2.8844 | Soluble |
| 222 | V | B | -1.4632 | Soluble |
| 223 | D | B | -2.0665 | Soluble |
| 224 | K | B | -1.7139 | Soluble |
| 225 | K | B | -2.2784 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.7647 | Soluble |
| 228 | P | B | -2.0629 | Soluble |
| 229 | K | B | -2.4695 | Soluble |
| 230 | S | B | -1.3537 | Soluble |
| 231 | C | B | -1.2345 | Soluble |
| 1 | D | E | -1.9624 | Soluble |
| 2 | I | E | -1.5243 | Soluble |
| 3 | Q | E | -1.9664 | Soluble |
| 4 | M | E | 0.0000 | Buried |
| 5 | T | E | -0.9626 | Soluble |
| 6 | Q | E | 0.0000 | Buried |
| 7 | S | E | -0.5316 | Soluble |
| 8 | P | E | -0.6145 | Soluble |
| 9 | S | E | -0.9180 | Soluble |
| 10 | S | E | -0.9864 | Soluble |
| 11 | L | E | -0.6851 | Soluble |
| 12 | S | E | -0.9793 | Soluble |
| 13 | A | E | 0.0000 | Buried |
| 14 | S | E | -1.0833 | Soluble |
| 15 | V | E | -0.1803 | Soluble |
| 16 | G | E | -0.8304 | Soluble |
| 17 | D | E | -1.8949 | Soluble |
| 18 | R | E | -2.3048 | Soluble |
| 19 | V | E | 0.0000 | Buried |
| 20 | T | E | -0.5170 | Soluble |
| 21 | I | E | 0.0000 | Buried |
| 22 | T | E | -0.6480 | Soluble |
| 23 | C | E | 0.0000 | Buried |
| 24 | R | E | -1.9590 | Soluble |
| 25 | A | E | 0.0000 | Buried |
| 26 | S | E | -1.7181 | Soluble |
| 27 | Q | E | -1.9500 | Soluble |
| 28 | G | E | -1.5806 | Soluble |
| 29 | I | E | 0.0000 | Buried |
| 36 | S | E | -1.0843 | Soluble |
| 37 | N | E | -1.2202 | Soluble |
| 38 | W | E | -0.2934 | Soluble |
| 39 | L | E | 0.0000 | Buried |
| 40 | A | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | Y | E | 0.0000 | Buried |
| 43 | Q | E | 0.0000 | Buried |
| 44 | Q | E | 0.0000 | Buried |
| 45 | K | E | -3.0224 | Soluble |
| 46 | P | E | -2.5680 | Soluble |
| 47 | E | E | -3.1064 | Soluble |
| 48 | K | E | -3.4364 | Soluble |
| 49 | A | E | -2.1816 | Soluble |
| 50 | P | E | 0.0000 | Buried |
| 51 | K | E | -1.9212 | Soluble |
| 52 | S | E | -0.6353 | Soluble |
| 53 | L | E | 0.0000 | Buried |
| 54 | I | E | 0.0000 | Buried |
| 55 | Y | E | 0.3747 | Aggregation-prone |
| 56 | A | E | -0.1211 | Soluble |
| 57 | A | E | 0.0000 | Buried |
| 65 | S | E | -0.2484 | Soluble |
| 66 | S | E | 0.1559 | Aggregation-prone |
| 67 | L | E | 0.3527 | Aggregation-prone |
| 68 | Q | E | -0.2946 | Soluble |
| 69 | S | E | -0.3928 | Soluble |
| 70 | G | E | -0.5104 | Soluble |
| 71 | V | E | -0.3646 | Soluble |
| 72 | P | E | -0.3436 | Soluble |
| 74 | S | E | -0.3957 | Soluble |
| 75 | R | E | -0.7226 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | S | E | -0.2718 | Soluble |
| 78 | G | E | -0.2012 | Soluble |
| 79 | S | E | -0.7448 | Soluble |
| 80 | G | E | -1.1798 | Soluble |
| 83 | S | E | -1.2933 | Soluble |
| 84 | G | E | -1.4484 | Soluble |
| 85 | T | E | -1.7779 | Soluble |
| 86 | D | E | -2.1865 | Soluble |
| 87 | F | E | 0.0000 | Buried |
| 88 | T | E | -0.6588 | Soluble |
| 89 | L | E | 0.0000 | Buried |
| 90 | T | E | -0.5811 | Soluble |
| 91 | I | E | 0.0000 | Buried |
| 92 | S | E | -1.3149 | Soluble |
| 93 | S | E | -1.1331 | Soluble |
| 94 | L | E | 0.0000 | Buried |
| 95 | Q | E | -1.1095 | Soluble |
| 96 | P | E | -1.7438 | Soluble |
| 97 | E | E | -2.0773 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | F | E | -1.3424 | Soluble |
| 100 | A | E | 0.0000 | Buried |
| 101 | T | E | -1.2759 | Soluble |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | Q | E | 0.0000 | Buried |
| 106 | Q | E | 0.0000 | Buried |
| 107 | Y | E | 0.0000 | Buried |
| 108 | D | E | -0.2561 | Soluble |
| 109 | S | E | 0.1838 | Aggregation-prone |
| 114 | Y | E | 0.0000 | Buried |
| 115 | P | E | 0.0000 | Buried |
| 116 | R | E | 0.0000 | Buried |
| 117 | T | E | 0.0000 | Buried |
| 118 | F | E | 0.0000 | Buried |
| 119 | G | E | 0.0000 | Buried |
| 120 | Q | E | -1.7110 | Soluble |
| 121 | G | E | 0.0000 | Buried |
| 122 | T | E | 0.0000 | Buried |
| 123 | K | E | -2.0949 | Soluble |
| 124 | V | E | 0.0000 | Buried |
| 125 | E | E | -1.4694 | Soluble |
| 126 | I | E | 0.0000 | Buried |
| 127 | K | E | -1.5829 | Soluble |
| 128 | R | E | -0.8479 | Soluble |
| 129 | T | E | 0.1049 | Aggregation-prone |
| 130 | V | E | 1.1396 | Aggregation-prone |
| 131 | A | E | 0.2313 | Aggregation-prone |
| 132 | A | E | 0.0161 | Aggregation-prone |
| 133 | P | E | 0.0000 | Buried |
| 134 | S | E | -0.2075 | Soluble |
| 135 | V | E | -0.1222 | Soluble |
| 136 | F | E | 0.0000 | Buried |
| 137 | I | E | 0.0000 | Buried |
| 138 | F | E | 0.0000 | Buried |
| 139 | P | E | -0.9217 | Soluble |
| 140 | P | E | -0.6868 | Soluble |
| 141 | S | E | -1.3546 | Soluble |
| 142 | D | E | -2.5436 | Soluble |
| 143 | E | E | -2.2330 | Soluble |
| 144 | Q | E | 0.0000 | Buried |
| 145 | L | E | -1.9204 | Soluble |
| 146 | K | E | -2.5420 | Soluble |
| 147 | S | E | -1.5973 | Soluble |
| 148 | G | E | -1.2966 | Soluble |
| 149 | T | E | -1.0914 | Soluble |
| 150 | A | E | 0.0000 | Buried |
| 151 | S | E | 0.0000 | Buried |
| 152 | V | E | 0.0000 | Buried |
| 153 | V | E | 0.0000 | Buried |
| 154 | C | E | 0.0000 | Buried |
| 155 | L | E | 0.0000 | Buried |
| 156 | L | E | 0.0000 | Buried |
| 157 | N | E | 0.0000 | Buried |
| 158 | N | E | -0.9802 | Soluble |
| 159 | F | E | 0.0000 | Buried |
| 160 | Y | E | 0.0000 | Buried |
| 161 | P | E | -1.7302 | Soluble |
| 162 | R | E | -3.1742 | Soluble |
| 163 | E | E | -3.2414 | Soluble |
| 164 | A | E | -2.4160 | Soluble |
| 165 | K | E | -2.5247 | Soluble |
| 166 | V | E | 0.0000 | Buried |
| 167 | Q | E | -0.7390 | Soluble |
| 168 | W | E | 0.0000 | Buried |
| 169 | K | E | -0.6450 | Soluble |
| 170 | V | E | 0.0000 | Buried |
| 171 | D | E | -1.2613 | Soluble |
| 172 | N | E | -1.2331 | Soluble |
| 173 | A | E | -0.3582 | Soluble |
| 174 | L | E | 0.4541 | Aggregation-prone |
| 175 | Q | E | -0.5405 | Soluble |
| 176 | S | E | -0.7479 | Soluble |
| 177 | G | E | -1.2637 | Soluble |
| 178 | N | E | -1.5881 | Soluble |
| 179 | S | E | -1.3009 | Soluble |
| 180 | Q | E | -0.9208 | Soluble |
| 181 | E | E | -1.3042 | Soluble |
| 182 | S | E | -0.5412 | Soluble |
| 183 | V | E | -0.7316 | Soluble |
| 184 | T | E | -1.1536 | Soluble |
| 185 | E | E | -2.2309 | Soluble |
| 186 | Q | E | 0.0000 | Buried |
| 187 | D | E | -2.0042 | Soluble |
| 188 | S | E | -2.1433 | Soluble |
| 189 | K | E | -2.5162 | Soluble |
| 190 | D | E | -1.7748 | Soluble |
| 191 | S | E | 0.0000 | Buried |
| 192 | T | E | 0.0000 | Buried |
| 193 | Y | E | 0.0000 | Buried |
| 194 | S | E | 0.0000 | Buried |
| 195 | L | E | 0.0000 | Buried |
| 196 | S | E | 0.0000 | Buried |
| 197 | S | E | 0.0000 | Buried |
| 198 | T | E | 0.0000 | Buried |
| 199 | L | E | 0.0000 | Buried |
| 200 | T | E | -0.5915 | Soluble |
| 201 | L | E | -0.8682 | Soluble |
| 202 | S | E | -1.2457 | Soluble |
| 203 | K | E | -2.0500 | Soluble |
| 204 | A | E | -1.9645 | Soluble |
| 205 | D | E | -2.6565 | Soluble |
| 206 | Y | E | 0.0000 | Buried |
| 207 | E | E | -3.6847 | Soluble |
| 208 | K | E | -3.5089 | Soluble |
| 209 | H | E | -2.7449 | Soluble |
| 210 | K | E | -3.0369 | Soluble |
| 211 | V | E | -1.4715 | Soluble |
| 212 | Y | E | 0.0000 | Buried |
| 213 | A | E | -0.5594 | Soluble |
| 214 | C | E | 0.0000 | Buried |
| 215 | E | E | -0.6604 | Soluble |
| 216 | V | E | 0.0000 | Buried |
| 217 | T | E | -1.1795 | Soluble |
| 218 | H | E | 0.0000 | Buried |
| 219 | Q | E | -1.6614 | Soluble |
| 220 | G | E | -0.2881 | Soluble |
| 221 | L | E | -0.1580 | Soluble |
| 222 | S | E | -0.4438 | Soluble |
| 223 | S | E | -0.3989 | Soluble |
| 224 | P | E | -0.5173 | Soluble |
| 225 | V | E | 0.1002 | Aggregation-prone |
| 226 | T | E | -0.3410 | Soluble |
| 227 | K | E | -0.5712 | Soluble |
| 228 | S | E | -0.6155 | Soluble |
| 229 | F | E | 0.0000 | Buried |
| 230 | N | E | -2.2357 | Soluble |
| 231 | R | E | -2.8835 | Soluble |
| 232 | G | E | -2.3661 | Soluble |
| 233 | E | E | -2.8087 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7201 | 4.5628 | CSV PDB |
| 4.5 | -0.7628 | 4.5421 | CSV PDB |
| 5.0 | -0.8127 | 4.5208 | CSV PDB |
| 5.5 | -0.8605 | 4.4994 | CSV PDB |
| 6.0 | -0.8944 | 4.48 | CSV PDB |
| 6.5 | -0.904 | 4.4663 | CSV PDB |
| 7.0 | -0.8877 | 4.4596 | CSV PDB |
| 7.5 | -0.8535 | 4.4585 | CSV PDB |
| 8.0 | -0.8088 | 4.4631 | CSV PDB |
| 8.5 | -0.7566 | 4.474 | CSV PDB |
| 9.0 | -0.6982 | 4.4895 | CSV PDB |