Calculation Parameters
| Chain Sequence(s) |
EVQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGKTYYRFKWYSDYAVSVKGRITINPDTSKNQFSLQLNSVTPEDTAVFYCTRESTTYDLLAGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIVMTQSPDSLAVSLGERATINCKSSQTVLYSSNNKKYLAWYQQKPGQPPNLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPFTFGPGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), C (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.2003 | Soluble |
| 2 | V | B | -1.7755 | Soluble |
| 3 | Q | B | -2.1990 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | Q | B | -1.8272 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7931 | Soluble |
| 8 | G | B | -0.4442 | Soluble |
| 9 | P | B | -0.4801 | Soluble |
| 11 | G | B | 0.0393 | Aggregation-prone |
| 12 | L | B | -0.2101 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | K | B | -2.2504 | Soluble |
| 15 | P | B | -1.7431 | Soluble |
| 16 | S | B | -1.4936 | Soluble |
| 17 | Q | B | -2.0252 | Soluble |
| 18 | T | B | -1.4354 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | S | B | -0.7839 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | T | B | -0.7313 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -1.2037 | Soluble |
| 25 | I | B | 0.0000 | Buried |
| 26 | S | B | -1.4791 | Soluble |
| 27 | G | B | -1.4749 | Soluble |
| 28 | D | B | -1.2746 | Soluble |
| 29 | S | B | -0.7708 | Soluble |
| 30 | V | B | 0.0000 | Buried |
| 31 | S | B | -0.4091 | Soluble |
| 34 | S | B | -0.5179 | Soluble |
| 35 | N | B | -0.7599 | Soluble |
| 36 | S | B | -0.0760 | Soluble |
| 37 | A | B | 0.0000 | Buried |
| 38 | A | B | 0.0000 | Buried |
| 39 | W | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | I | B | 0.0000 | Buried |
| 43 | R | B | -0.4167 | Soluble |
| 44 | Q | B | -0.5238 | Soluble |
| 45 | S | B | 0.0000 | Buried |
| 46 | P | B | -0.6087 | Soluble |
| 47 | S | B | -0.9411 | Soluble |
| 48 | R | B | -1.3434 | Soluble |
| 49 | G | B | -0.9543 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.8811 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | K | B | 0.0000 | Buried |
| 56 | T | B | 0.0000 | Buried |
| 57 | Y | B | 0.2417 | Aggregation-prone |
| 58 | Y | B | 0.3610 | Aggregation-prone |
| 59 | R | B | 0.0000 | Buried |
| 60 | F | B | 1.1572 | Aggregation-prone |
| 62 | K | B | -0.4459 | Soluble |
| 63 | W | B | 0.1920 | Aggregation-prone |
| 64 | Y | B | 0.3371 | Aggregation-prone |
| 65 | S | B | -0.1453 | Soluble |
| 66 | D | B | -0.5159 | Soluble |
| 67 | Y | B | -0.2474 | Soluble |
| 68 | A | B | 0.2032 | Aggregation-prone |
| 69 | V | B | 0.9805 | Aggregation-prone |
| 70 | S | B | 0.1049 | Aggregation-prone |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -1.4885 | Soluble |
| 74 | G | B | -1.3024 | Soluble |
| 75 | R | B | -1.4830 | Soluble |
| 76 | I | B | 0.0000 | Buried |
| 77 | T | B | -1.1169 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | N | B | -1.4654 | Soluble |
| 80 | P | B | -1.1623 | Soluble |
| 81 | D | B | -1.5488 | Soluble |
| 82 | T | B | -1.2486 | Soluble |
| 83 | S | B | -1.3301 | Soluble |
| 84 | K | B | -2.1616 | Soluble |
| 85 | N | B | -1.6201 | Soluble |
| 86 | Q | B | -1.4649 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | S | B | -0.8403 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.1289 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | N | B | -1.3320 | Soluble |
| 93 | S | B | -1.2624 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | T | B | -1.4148 | Soluble |
| 96 | P | B | -1.4386 | Soluble |
| 97 | E | B | -2.0709 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.5071 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.3426 | Aggregation-prone |
| 102 | F | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | T | B | 0.0000 | Buried |
| 106 | R | B | -0.3631 | Soluble |
| 107 | E | B | 0.0000 | Buried |
| 108 | S | B | 0.1479 | Aggregation-prone |
| 109 | T | B | 0.0000 | Buried |
| 110 | T | B | 0.6869 | Aggregation-prone |
| 111 | Y | B | 1.4615 | Aggregation-prone |
| 111A | D | B | 0.9657 | Aggregation-prone |
| 112B | L | B | 1.3845 | Aggregation-prone |
| 112A | L | B | 1.7818 | Aggregation-prone |
| 112 | A | B | 1.0408 | Aggregation-prone |
| 113 | G | B | 0.0000 | Buried |
| 114 | P | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | -0.4914 | Soluble |
| 117 | Y | B | -0.6613 | Soluble |
| 118 | W | B | -0.7436 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.7502 | Soluble |
| 121 | G | B | -0.8020 | Soluble |
| 122 | T | B | 0.0265 | Aggregation-prone |
| 123 | L | B | 0.6221 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.3213 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.7969 | Soluble |
| 128 | S | B | -0.8833 | Soluble |
| 129 | A | B | -0.5286 | Soluble |
| 130 | S | B | -0.6404 | Soluble |
| 131 | T | B | -0.9067 | Soluble |
| 132 | K | B | -1.2104 | Soluble |
| 133 | G | B | -1.4416 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4731 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1696 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.2469 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -0.7430 | Soluble |
| 143 | S | B | -0.1664 | Soluble |
| 144 | G | B | -0.7852 | Soluble |
| 145 | G | B | -0.8736 | Soluble |
| 146 | T | B | -0.6000 | Soluble |
| 147 | A | B | 0.0000 | Buried |
| 148 | A | B | 0.0000 | Buried |
| 149 | L | B | 0.0000 | Buried |
| 150 | G | B | 0.0000 | Buried |
| 151 | C | B | 0.0000 | Buried |
| 152 | L | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | K | B | 0.0000 | Buried |
| 155 | D | B | -0.4803 | Soluble |
| 156 | Y | B | 0.0000 | Buried |
| 157 | F | B | 0.0000 | Buried |
| 158 | P | B | 0.0000 | Buried |
| 159 | E | B | -0.2556 | Soluble |
| 160 | P | B | -0.5811 | Soluble |
| 161 | V | B | -0.7923 | Soluble |
| 162 | T | B | -0.7760 | Soluble |
| 163 | V | B | -0.3082 | Soluble |
| 164 | S | B | -0.4603 | Soluble |
| 165 | W | B | 0.0000 | Buried |
| 166 | N | B | -0.6945 | Soluble |
| 167 | S | B | -0.6276 | Soluble |
| 168 | G | B | -0.5608 | Soluble |
| 169 | A | B | -0.2193 | Soluble |
| 170 | L | B | 0.0480 | Aggregation-prone |
| 171 | T | B | -0.1276 | Soluble |
| 172 | S | B | -0.1898 | Soluble |
| 173 | G | B | -0.2373 | Soluble |
| 174 | V | B | 0.1721 | Aggregation-prone |
| 175 | H | B | -0.1112 | Soluble |
| 176 | T | B | 0.0465 | Aggregation-prone |
| 177 | F | B | 0.0000 | Buried |
| 178 | P | B | -0.4072 | Soluble |
| 179 | A | B | 0.1712 | Aggregation-prone |
| 180 | V | B | 0.4288 | Aggregation-prone |
| 181 | L | B | 1.0983 | Aggregation-prone |
| 182 | Q | B | 0.0640 | Aggregation-prone |
| 183 | S | B | -0.2374 | Soluble |
| 184 | S | B | -0.2455 | Soluble |
| 185 | G | B | 0.0090 | Aggregation-prone |
| 186 | L | B | 0.1246 | Aggregation-prone |
| 187 | Y | B | 0.4389 | Aggregation-prone |
| 188 | S | B | 0.0000 | Buried |
| 189 | L | B | 0.1178 | Aggregation-prone |
| 190 | S | B | 0.0000 | Buried |
| 191 | S | B | 0.0000 | Buried |
| 192 | V | B | 0.0000 | Buried |
| 193 | V | B | 0.0000 | Buried |
| 194 | T | B | -0.1439 | Soluble |
| 195 | V | B | 0.0000 | Buried |
| 196 | P | B | -0.6438 | Soluble |
| 197 | S | B | -0.6487 | Soluble |
| 198 | S | B | -0.6066 | Soluble |
| 199 | S | B | -0.5627 | Soluble |
| 200 | L | B | -0.7723 | Soluble |
| 201 | G | B | -0.9124 | Soluble |
| 202 | T | B | -0.6562 | Soluble |
| 203 | Q | B | -1.1529 | Soluble |
| 204 | T | B | -1.0478 | Soluble |
| 205 | Y | B | 0.0000 | Buried |
| 206 | I | B | -1.0483 | Soluble |
| 207 | C | B | 0.0000 | Buried |
| 208 | N | B | -1.5619 | Soluble |
| 209 | V | B | 0.0000 | Buried |
| 210 | N | B | -2.6319 | Soluble |
| 211 | H | B | 0.0000 | Buried |
| 212 | K | B | -2.9407 | Soluble |
| 213 | P | B | -1.6999 | Soluble |
| 214 | S | B | -1.9445 | Soluble |
| 215 | N | B | -2.7310 | Soluble |
| 216 | T | B | -2.2798 | Soluble |
| 217 | K | B | -2.9123 | Soluble |
| 218 | V | B | -1.6742 | Soluble |
| 219 | D | B | -2.4293 | Soluble |
| 220 | K | B | -1.9009 | Soluble |
| 221 | K | B | -2.4526 | Soluble |
| 222 | V | B | 0.0000 | Buried |
| 223 | E | B | -2.8763 | Soluble |
| 224 | P | B | -1.8967 | Soluble |
| 225 | K | B | -2.2108 | Soluble |
| 226 | S | B | -0.8781 | Soluble |
| 227 | C | B | 0.0291 | Aggregation-prone |
| 1 | D | C | -1.5449 | Soluble |
| 2 | I | C | 0.0000 | Buried |
| 3 | V | C | 0.8259 | Aggregation-prone |
| 4 | M | C | 0.0000 | Buried |
| 5 | T | C | -0.6778 | Soluble |
| 6 | Q | C | -1.4540 | Soluble |
| 7 | S | C | -1.4550 | Soluble |
| 8 | P | C | -1.5329 | Soluble |
| 9 | D | C | -2.4132 | Soluble |
| 10 | S | C | -1.5417 | Soluble |
| 11 | L | C | -0.8007 | Soluble |
| 12 | A | C | -0.6970 | Soluble |
| 13 | V | C | -1.0393 | Soluble |
| 14 | S | C | -1.0968 | Soluble |
| 15 | L | C | -0.1925 | Soluble |
| 16 | G | C | -1.0518 | Soluble |
| 17 | E | C | -2.6549 | Soluble |
| 18 | R | C | -2.7309 | Soluble |
| 19 | A | C | 0.0000 | Buried |
| 20 | T | C | -0.7076 | Soluble |
| 21 | I | C | 0.0000 | Buried |
| 22 | N | C | -1.7802 | Soluble |
| 23 | C | C | 0.0000 | Buried |
| 24 | K | C | -1.9114 | Soluble |
| 25 | S | C | 0.0000 | Buried |
| 26 | S | C | -0.8524 | Soluble |
| 27 | Q | C | -1.4412 | Soluble |
| 28 | T | C | -0.7814 | Soluble |
| 29 | V | C | 0.0000 | Buried |
| 30 | L | C | -0.1368 | Soluble |
| 31 | Y | C | 0.2497 | Aggregation-prone |
| 32 | S | C | -0.5067 | Soluble |
| 33 | S | C | -0.6741 | Soluble |
| 34 | N | C | -1.0919 | Soluble |
| 35 | N | C | -1.5752 | Soluble |
| 36 | K | C | -1.0800 | Soluble |
| 37 | K | C | -0.6390 | Soluble |
| 38 | Y | C | 0.0000 | Buried |
| 39 | L | C | 0.0000 | Buried |
| 40 | A | C | 0.0000 | Buried |
| 41 | W | C | 0.0000 | Buried |
| 42 | Y | C | 0.0000 | Buried |
| 43 | Q | C | -0.7026 | Soluble |
| 44 | Q | C | -1.0164 | Soluble |
| 45 | K | C | -1.4862 | Soluble |
| 46 | P | C | -1.2843 | Soluble |
| 47 | G | C | -1.3241 | Soluble |
| 48 | Q | C | -1.7637 | Soluble |
| 49 | P | C | -1.1649 | Soluble |
| 50 | P | C | 0.0000 | Buried |
| 51 | N | C | -0.9276 | Soluble |
| 52 | L | C | 0.0000 | Buried |
| 53 | L | C | 0.0000 | Buried |
| 54 | I | C | 0.0000 | Buried |
| 55 | Y | C | -0.1147 | Soluble |
| 56 | W | C | -0.3187 | Soluble |
| 57 | A | C | 0.0000 | Buried |
| 65 | S | C | -0.5500 | Soluble |
| 66 | T | C | -0.4739 | Soluble |
| 67 | R | C | -1.2258 | Soluble |
| 68 | E | C | -1.0528 | Soluble |
| 69 | S | C | -0.8894 | Soluble |
| 70 | G | C | -0.9044 | Soluble |
| 71 | V | C | -0.9937 | Soluble |
| 72 | P | C | -1.3454 | Soluble |
| 74 | D | C | -2.2807 | Soluble |
| 75 | R | C | -1.6377 | Soluble |
| 76 | F | C | 0.0000 | Buried |
| 77 | S | C | -0.9310 | Soluble |
| 78 | G | C | -0.4915 | Soluble |
| 79 | S | C | -0.7047 | Soluble |
| 80 | G | C | -1.0057 | Soluble |
| 83 | S | C | -0.7947 | Soluble |
| 84 | G | C | -0.9026 | Soluble |
| 85 | T | C | -1.3710 | Soluble |
| 86 | D | C | -1.9989 | Soluble |
| 87 | F | C | 0.0000 | Buried |
| 88 | T | C | -0.9851 | Soluble |
| 89 | L | C | 0.0000 | Buried |
| 90 | T | C | -0.7216 | Soluble |
| 91 | I | C | 0.0000 | Buried |
| 92 | S | C | -1.7329 | Soluble |
| 93 | S | C | -1.4707 | Soluble |
| 94 | L | C | 0.0000 | Buried |
| 95 | Q | C | -1.4496 | Soluble |
| 96 | A | C | -1.7509 | Soluble |
| 97 | E | C | -2.6289 | Soluble |
| 98 | D | C | 0.0000 | Buried |
| 99 | V | C | 0.0000 | Buried |
| 100 | A | C | 0.0000 | Buried |
| 101 | V | C | -0.8794 | Soluble |
| 102 | Y | C | 0.0000 | Buried |
| 103 | Y | C | 0.0000 | Buried |
| 104 | C | C | 0.0000 | Buried |
| 105 | Q | C | 0.0000 | Buried |
| 106 | Q | C | 0.0000 | Buried |
| 107 | Y | C | 0.0000 | Buried |
| 108 | Y | C | 0.4064 | Aggregation-prone |
| 109 | S | C | -0.3012 | Soluble |
| 114 | T | C | -0.5068 | Soluble |
| 115 | P | C | -0.3748 | Soluble |
| 116 | F | C | 0.0000 | Buried |
| 117 | T | C | -0.0842 | Soluble |
| 118 | F | C | 0.0000 | Buried |
| 119 | G | C | 0.0000 | Buried |
| 120 | P | C | -0.7046 | Soluble |
| 121 | G | C | -0.9854 | Soluble |
| 122 | T | C | 0.0000 | Buried |
| 123 | K | C | -1.8405 | Soluble |
| 124 | V | C | 0.0000 | Buried |
| 125 | E | C | -1.2535 | Soluble |
| 126 | I | C | 0.0000 | Buried |
| 127 | K | C | -1.5376 | Soluble |
| 128 | R | C | -0.9075 | Soluble |
| 129 | T | C | -0.1370 | Soluble |
| 130 | V | C | 0.4232 | Aggregation-prone |
| 131 | A | C | 0.0547 | Aggregation-prone |
| 132 | A | C | -0.1051 | Soluble |
| 133 | P | C | 0.0000 | Buried |
| 134 | S | C | -0.1875 | Soluble |
| 135 | V | C | 0.0000 | Buried |
| 136 | F | C | 0.2226 | Aggregation-prone |
| 137 | I | C | 0.1590 | Aggregation-prone |
| 138 | F | C | 0.0000 | Buried |
| 139 | P | C | -0.5215 | Soluble |
| 140 | P | C | -0.8439 | Soluble |
| 141 | S | C | -1.8580 | Soluble |
| 142 | D | C | -2.9851 | Soluble |
| 143 | E | C | -3.0240 | Soluble |
| 144 | Q | C | 0.0000 | Buried |
| 145 | L | C | -2.2959 | Soluble |
| 146 | K | C | -2.8919 | Soluble |
| 147 | S | C | -1.8235 | Soluble |
| 148 | G | C | -1.2716 | Soluble |
| 149 | T | C | -1.2588 | Soluble |
| 150 | A | C | 0.0000 | Buried |
| 151 | S | C | 0.0000 | Buried |
| 152 | V | C | 0.0000 | Buried |
| 153 | V | C | 0.0000 | Buried |
| 154 | C | C | 0.0000 | Buried |
| 155 | L | C | 0.0000 | Buried |
| 156 | L | C | 0.0000 | Buried |
| 157 | N | C | 0.0000 | Buried |
| 158 | N | C | -0.7982 | Soluble |
| 159 | F | C | 0.0000 | Buried |
| 160 | Y | C | 0.0000 | Buried |
| 161 | P | C | -1.3777 | Soluble |
| 162 | R | C | -2.2679 | Soluble |
| 163 | E | C | -2.8626 | Soluble |
| 164 | A | C | -2.1142 | Soluble |
| 165 | K | C | -2.2037 | Soluble |
| 166 | V | C | -1.1470 | Soluble |
| 167 | Q | C | -0.7626 | Soluble |
| 168 | W | C | 0.0000 | Buried |
| 169 | K | C | -0.7721 | Soluble |
| 170 | V | C | 0.0000 | Buried |
| 171 | D | C | -2.0985 | Soluble |
| 172 | N | C | -1.6585 | Soluble |
| 173 | A | C | -0.3662 | Soluble |
| 174 | L | C | 0.6199 | Aggregation-prone |
| 175 | Q | C | -0.3845 | Soluble |
| 176 | S | C | -0.7874 | Soluble |
| 177 | G | C | -1.3622 | Soluble |
| 178 | N | C | -1.8023 | Soluble |
| 179 | S | C | -1.6672 | Soluble |
| 180 | Q | C | -1.7589 | Soluble |
| 181 | E | C | -1.9716 | Soluble |
| 182 | S | C | -0.9228 | Soluble |
| 183 | V | C | -0.4507 | Soluble |
| 184 | T | C | -0.9375 | Soluble |
| 185 | E | C | -2.0094 | Soluble |
| 186 | Q | C | 0.0000 | Buried |
| 187 | D | C | -2.0891 | Soluble |
| 188 | S | C | -2.4101 | Soluble |
| 189 | K | C | -2.6565 | Soluble |
| 190 | D | C | -1.8546 | Soluble |
| 191 | S | C | 0.0000 | Buried |
| 192 | T | C | 0.0000 | Buried |
| 193 | Y | C | 0.0000 | Buried |
| 194 | S | C | 0.0000 | Buried |
| 195 | L | C | 0.0000 | Buried |
| 196 | S | C | 0.0000 | Buried |
| 197 | S | C | 0.0000 | Buried |
| 198 | T | C | -0.8327 | Soluble |
| 199 | L | C | 0.0000 | Buried |
| 200 | T | C | -0.7072 | Soluble |
| 201 | L | C | -0.9173 | Soluble |
| 202 | S | C | -1.1399 | Soluble |
| 203 | K | C | -2.1954 | Soluble |
| 204 | A | C | -2.0360 | Soluble |
| 205 | D | C | -2.7799 | Soluble |
| 206 | Y | C | 0.0000 | Buried |
| 207 | E | C | -3.7834 | Soluble |
| 208 | K | C | -3.8076 | Soluble |
| 209 | H | C | -3.1113 | Soluble |
| 210 | K | C | -3.3286 | Soluble |
| 211 | V | C | -1.4583 | Soluble |
| 212 | Y | C | 0.0000 | Buried |
| 213 | A | C | 0.0000 | Buried |
| 214 | C | C | 0.0000 | Buried |
| 215 | E | C | -0.9584 | Soluble |
| 216 | V | C | 0.0000 | Buried |
| 217 | T | C | -1.1724 | Soluble |
| 218 | H | C | 0.0000 | Buried |
| 219 | Q | C | -1.4950 | Soluble |
| 220 | G | C | -0.4103 | Soluble |
| 221 | L | C | -0.2076 | Soluble |
| 222 | S | C | -0.4346 | Soluble |
| 223 | S | C | -0.4351 | Soluble |
| 224 | P | C | -0.5807 | Soluble |
| 225 | V | C | -0.0033 | Soluble |
| 226 | T | C | -0.4987 | Soluble |
| 227 | K | C | -0.6747 | Soluble |
| 228 | S | C | -0.5257 | Soluble |
| 229 | F | C | -0.7496 | Soluble |
| 230 | N | C | -1.7177 | Soluble |
| 231 | R | C | -2.5065 | Soluble |
| 232 | G | C | -1.9596 | Soluble |
| 233 | E | C | -2.0289 | Soluble |
| 234 | C | C | -0.2892 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6409 | 2.6394 | CSV PDB |
| 4.5 | -0.6885 | 2.6421 | CSV PDB |
| 5.0 | -0.7432 | 2.6503 | CSV PDB |
| 5.5 | -0.7939 | 2.6744 | CSV PDB |
| 6.0 | -0.8289 | 2.7365 | CSV PDB |
| 6.5 | -0.8388 | 2.8615 | CSV PDB |
| 7.0 | -0.8241 | 3.048 | CSV PDB |
| 7.5 | -0.7932 | 3.2703 | CSV PDB |
| 8.0 | -0.7536 | 3.5071 | CSV PDB |
| 8.5 | -0.7073 | 3.7484 | CSV PDB |
| 9.0 | -0.6541 | 3.9898 | CSV PDB |