Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGRSLRLSCAASGFTFHDYAMHWVRQVPGKGLEWVSGISWRGDIGGYVKSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCVKSYGSGSFYNAFDSWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKDIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKFLIYKASKLERGTPSRFSGSGDGTEFSLTISSLQPDDFATYYCLEYSSYIRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDAALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -1.6999 | Soluble |
| 2 | V | A | -0.4590 | Soluble |
| 3 | Q | A | -0.6752 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.2370 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.1755 | Soluble |
| 8 | G | A | -0.8876 | Soluble |
| 9 | G | A | -0.4762 | Soluble |
| 11 | G | A | -0.2419 | Soluble |
| 12 | L | A | -0.1210 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -2.2064 | Soluble |
| 15 | P | A | -2.2129 | Soluble |
| 16 | G | A | -2.3909 | Soluble |
| 17 | R | A | -2.9247 | Soluble |
| 18 | S | A | -2.2415 | Soluble |
| 19 | L | A | -1.4869 | Soluble |
| 20 | R | A | -2.1415 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.3597 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.0985 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.6677 | Soluble |
| 27 | G | A | -0.8341 | Soluble |
| 28 | F | A | -0.5569 | Soluble |
| 29 | T | A | -0.9231 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | H | A | -2.1050 | Soluble |
| 36 | D | A | -2.2628 | Soluble |
| 37 | Y | A | -1.0208 | Soluble |
| 38 | A | A | 0.0000 | Buried |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.2861 | Soluble |
| 44 | Q | A | 0.0000 | Buried |
| 45 | V | A | -0.6591 | Soluble |
| 46 | P | A | -1.0434 | Soluble |
| 47 | G | A | -1.4802 | Soluble |
| 48 | K | A | -2.1546 | Soluble |
| 49 | G | A | -1.4879 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.4590 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | S | A | 0.0000 | Buried |
| 55 | G | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | W | A | -1.2647 | Soluble |
| 59 | R | A | -2.5991 | Soluble |
| 62 | G | A | -1.9797 | Soluble |
| 63 | D | A | -2.0512 | Soluble |
| 64 | I | A | -0.3684 | Soluble |
| 65 | G | A | -0.2841 | Soluble |
| 66 | G | A | -0.1920 | Soluble |
| 67 | Y | A | -0.6801 | Soluble |
| 68 | V | A | 0.0000 | Buried |
| 69 | K | A | -2.0857 | Soluble |
| 70 | S | A | -1.5874 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.3621 | Soluble |
| 74 | G | A | -1.7696 | Soluble |
| 75 | R | A | -1.5407 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.9681 | Soluble |
| 78 | I | A | -0.4962 | Soluble |
| 79 | S | A | -0.4364 | Soluble |
| 80 | R | A | -1.1891 | Soluble |
| 81 | D | A | -1.7698 | Soluble |
| 82 | N | A | -2.1245 | Soluble |
| 83 | A | A | -1.4475 | Soluble |
| 84 | K | A | -2.2561 | Soluble |
| 85 | N | A | -1.8167 | Soluble |
| 86 | S | A | 0.0000 | Buried |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.5510 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.3187 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -2.1062 | Soluble |
| 93 | S | A | -2.0895 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.0476 | Soluble |
| 96 | A | A | -1.9901 | Soluble |
| 97 | E | A | -2.3273 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7051 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | L | A | 0.1245 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | V | A | 0.0000 | Buried |
| 106 | K | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | Y | A | 0.0000 | Buried |
| 109 | G | A | -0.8100 | Soluble |
| 110 | S | A | -0.6005 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | S | A | 0.2081 | Aggregation-prone |
| 112A | F | A | 0.0000 | Buried |
| 112 | Y | A | 1.5794 | Aggregation-prone |
| 113 | N | A | 0.4676 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.6255 | Soluble |
| 117 | S | A | -0.2874 | Soluble |
| 118 | W | A | -0.4600 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2494 | Soluble |
| 121 | G | A | -0.3896 | Soluble |
| 122 | T | A | 0.0876 | Aggregation-prone |
| 123 | L | A | 0.2639 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.5041 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.9605 | Soluble |
| 128 | S | A | -0.6269 | Soluble |
| 129 | A | A | -0.5460 | Soluble |
| 130 | S | A | -0.7511 | Soluble |
| 131 | T | A | -1.0424 | Soluble |
| 132 | K | A | -1.7894 | Soluble |
| 133 | G | A | -1.7062 | Soluble |
| 134 | P | A | -0.7613 | Soluble |
| 135 | S | A | -0.3692 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1993 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.9635 | Soluble |
| 141 | P | A | -0.7960 | Soluble |
| 142 | C | A | -0.8615 | Soluble |
| 143 | S | A | -1.2643 | Soluble |
| 144 | R | A | -1.8418 | Soluble |
| 145 | S | A | -1.2282 | Soluble |
| 146 | T | A | -0.8420 | Soluble |
| 147 | S | A | -0.7873 | Soluble |
| 148 | E | A | -1.0502 | Soluble |
| 149 | S | A | -0.6390 | Soluble |
| 150 | T | A | -0.5937 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.6076 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.7071 | Soluble |
| 164 | P | A | -0.7044 | Soluble |
| 165 | V | A | -0.6384 | Soluble |
| 166 | T | A | -0.4877 | Soluble |
| 167 | V | A | -0.0757 | Soluble |
| 168 | S | A | -0.3919 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -1.0643 | Soluble |
| 171 | S | A | -0.7274 | Soluble |
| 172 | G | A | -0.5604 | Soluble |
| 173 | A | A | -0.2719 | Soluble |
| 174 | L | A | -0.2436 | Soluble |
| 175 | T | A | -0.1908 | Soluble |
| 176 | S | A | -0.1474 | Soluble |
| 177 | G | A | -0.1336 | Soluble |
| 178 | V | A | 0.2152 | Aggregation-prone |
| 179 | H | A | -0.3075 | Soluble |
| 180 | T | A | 0.0650 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.2092 | Soluble |
| 183 | A | A | 0.3213 | Aggregation-prone |
| 184 | V | A | 0.5439 | Aggregation-prone |
| 185 | L | A | 1.0858 | Aggregation-prone |
| 186 | Q | A | 0.1438 | Aggregation-prone |
| 187 | S | A | -0.0993 | Soluble |
| 188 | S | A | -0.2475 | Soluble |
| 189 | G | A | 0.0319 | Aggregation-prone |
| 190 | L | A | -0.0499 | Soluble |
| 191 | Y | A | 0.3537 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.3554 | Aggregation-prone |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | 0.0130 | Aggregation-prone |
| 199 | V | A | -0.0035 | Soluble |
| 200 | P | A | -0.3678 | Soluble |
| 201 | S | A | -0.6567 | Soluble |
| 202 | S | A | -0.3743 | Soluble |
| 203 | S | A | -0.4683 | Soluble |
| 204 | L | A | -0.4063 | Soluble |
| 205 | G | A | -0.8297 | Soluble |
| 206 | T | A | -0.8746 | Soluble |
| 207 | K | A | -1.3945 | Soluble |
| 208 | T | A | -1.3582 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | T | A | -1.8430 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | 0.0000 | Buried |
| 213 | V | A | 0.0000 | Buried |
| 214 | D | A | -1.7520 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7455 | Soluble |
| 217 | P | A | -1.7273 | Soluble |
| 218 | S | A | -2.0060 | Soluble |
| 219 | N | A | -2.6300 | Soluble |
| 220 | T | A | -2.1311 | Soluble |
| 221 | K | A | -2.6430 | Soluble |
| 222 | V | A | -1.6337 | Soluble |
| 223 | D | A | -2.6155 | Soluble |
| 224 | K | A | -2.3476 | Soluble |
| 225 | R | A | -2.8327 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.8784 | Soluble |
| 228 | S | A | -2.0328 | Soluble |
| 229 | K | A | -2.3805 | Soluble |
| 1 | D | B | -2.0622 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.1930 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.5155 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8255 | Soluble |
| 8 | P | B | -0.5397 | Soluble |
| 9 | S | B | -0.7621 | Soluble |
| 10 | T | B | -0.5298 | Soluble |
| 11 | L | B | -0.3960 | Soluble |
| 12 | S | B | -0.5680 | Soluble |
| 13 | A | B | -0.8991 | Soluble |
| 14 | S | B | -0.8980 | Soluble |
| 15 | V | B | -0.4038 | Soluble |
| 16 | G | B | -0.9884 | Soluble |
| 17 | D | B | -1.7873 | Soluble |
| 18 | R | B | -2.3561 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.5342 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.8891 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -3.0411 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.1054 | Soluble |
| 27 | Q | B | -2.2523 | Soluble |
| 28 | S | B | -1.6018 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | S | B | -1.1954 | Soluble |
| 37 | S | B | -1.1259 | Soluble |
| 38 | W | B | -0.0288 | Soluble |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.6420 | Soluble |
| 46 | P | B | -1.4578 | Soluble |
| 47 | G | B | -1.7273 | Soluble |
| 48 | K | B | -2.4549 | Soluble |
| 49 | A | B | -1.6565 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.6950 | Soluble |
| 52 | F | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.8306 | Soluble |
| 56 | K | B | -1.5817 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -1.5275 | Soluble |
| 66 | K | B | -2.1203 | Soluble |
| 67 | L | B | -1.2165 | Soluble |
| 68 | E | B | -1.5762 | Soluble |
| 69 | R | B | -2.2631 | Soluble |
| 70 | G | B | -1.4063 | Soluble |
| 71 | T | B | -1.0631 | Soluble |
| 72 | P | B | -0.6978 | Soluble |
| 74 | S | B | -0.4964 | Soluble |
| 75 | R | B | -0.9228 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.6349 | Soluble |
| 78 | G | B | -0.7483 | Soluble |
| 79 | S | B | -1.3458 | Soluble |
| 80 | G | B | -1.9587 | Soluble |
| 83 | D | B | -2.7000 | Soluble |
| 84 | G | B | -1.9760 | Soluble |
| 85 | T | B | -2.3354 | Soluble |
| 86 | E | B | -2.8255 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | S | B | -0.9943 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6338 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3522 | Soluble |
| 93 | S | B | -1.2556 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.3585 | Soluble |
| 96 | P | B | -2.0018 | Soluble |
| 97 | D | B | -2.5795 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.8058 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | L | B | 0.0000 | Buried |
| 106 | E | B | 0.0000 | Buried |
| 107 | Y | B | 0.0000 | Buried |
| 108 | S | B | 0.5050 | Aggregation-prone |
| 109 | S | B | 0.4731 | Aggregation-prone |
| 114 | Y | B | 1.1300 | Aggregation-prone |
| 115 | I | B | 0.3683 | Aggregation-prone |
| 116 | R | B | 0.0000 | Buried |
| 117 | T | B | -0.5453 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.7066 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.1188 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -0.9792 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.0909 | Soluble |
| 128 | R | B | -0.9486 | Soluble |
| 129 | T | B | -0.0865 | Soluble |
| 130 | V | B | 0.4756 | Aggregation-prone |
| 131 | A | B | 0.1995 | Aggregation-prone |
| 132 | A | B | -0.0526 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2142 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | 0.0000 | Buried |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.1535 | Soluble |
| 142 | D | B | -2.0219 | Soluble |
| 143 | E | B | -1.7935 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.5489 | Soluble |
| 146 | K | B | -2.3701 | Soluble |
| 147 | S | B | -1.4842 | Soluble |
| 148 | G | B | -1.1254 | Soluble |
| 149 | T | B | -0.7599 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8691 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6571 | Soluble |
| 162 | R | B | -2.7882 | Soluble |
| 163 | E | B | -3.1527 | Soluble |
| 164 | A | B | -2.2340 | Soluble |
| 165 | K | B | -2.0983 | Soluble |
| 166 | V | B | -1.0457 | Soluble |
| 167 | Q | B | -0.6775 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.2839 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4052 | Soluble |
| 172 | A | B | -0.2154 | Soluble |
| 173 | A | B | 0.2372 | Aggregation-prone |
| 174 | L | B | 0.9244 | Aggregation-prone |
| 175 | Q | B | -0.0289 | Soluble |
| 176 | S | B | -0.4792 | Soluble |
| 177 | G | B | -0.9708 | Soluble |
| 178 | N | B | -0.9239 | Soluble |
| 179 | S | B | -1.2067 | Soluble |
| 180 | Q | B | -1.5393 | Soluble |
| 181 | E | B | -1.5055 | Soluble |
| 182 | S | B | -0.7167 | Soluble |
| 183 | V | B | -0.5553 | Soluble |
| 184 | T | B | -1.1691 | Soluble |
| 185 | E | B | -2.3215 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.4884 | Soluble |
| 188 | S | B | -2.5180 | Soluble |
| 189 | K | B | -2.8155 | Soluble |
| 190 | D | B | -2.0422 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6618 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3229 | Soluble |
| 201 | L | B | -0.5062 | Soluble |
| 202 | S | B | -0.9029 | Soluble |
| 203 | K | B | -1.8900 | Soluble |
| 204 | A | B | -1.6607 | Soluble |
| 205 | D | B | -2.2277 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.5316 | Soluble |
| 208 | K | B | -3.4954 | Soluble |
| 209 | H | B | -3.1492 | Soluble |
| 210 | K | B | -3.2429 | Soluble |
| 211 | V | B | -1.2952 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.4892 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7071 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1558 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6863 | Soluble |
| 220 | G | B | -0.3926 | Soluble |
| 221 | L | B | -0.2361 | Soluble |
| 222 | S | B | -0.4752 | Soluble |
| 223 | S | B | -0.4217 | Soluble |
| 224 | P | B | -0.5103 | Soluble |
| 225 | V | B | 0.0670 | Aggregation-prone |
| 226 | T | B | -0.4151 | Soluble |
| 227 | K | B | -0.5929 | Soluble |
| 228 | S | B | -0.5447 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.7385 | Soluble |
| 231 | R | B | -2.3199 | Soluble |
| 232 | G | B | -2.0476 | Soluble |
| 233 | E | B | -2.2788 | Soluble |
| 234 | C | B | -1.2377 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.8808 | 1.6803 | CSV PDB |
| 4.5 | -0.9233 | 1.6803 | CSV PDB |
| 5.0 | -0.9725 | 1.6803 | CSV PDB |
| 5.5 | -1.0183 | 1.6803 | CSV PDB |
| 6.0 | -1.0495 | 1.6803 | CSV PDB |
| 6.5 | -1.0577 | 1.6803 | CSV PDB |
| 7.0 | -1.0437 | 1.6802 | CSV PDB |
| 7.5 | -1.0149 | 1.6801 | CSV PDB |
| 8.0 | -0.9779 | 1.6796 | CSV PDB |
| 8.5 | -0.9342 | 1.678 | CSV PDB |
| 9.0 | -0.8839 | 1.673 | CSV PDB |