Calculation Parameters
| Chain Sequence(s) |
VQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPEIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | A | 1.7231 | Aggregation-prone |
| 3 | Q | A | 0.1039 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.0339 | Aggregation-prone |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.3402 | Soluble |
| 8 | G | A | 0.1987 | Aggregation-prone |
| 9 | V | A | 1.5252 | Aggregation-prone |
| 11 | E | A | 0.3879 | Aggregation-prone |
| 12 | V | A | 0.4454 | Aggregation-prone |
| 13 | K | A | -0.7566 | Soluble |
| 14 | K | A | -1.4532 | Soluble |
| 15 | P | A | -1.3249 | Soluble |
| 16 | G | A | -1.2601 | Soluble |
| 17 | A | A | -1.2767 | Soluble |
| 18 | S | A | -1.6662 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.1223 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6110 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.1444 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | 0.0026 | Aggregation-prone |
| 27 | G | A | -0.0053 | Soluble |
| 28 | Y | A | 1.0551 | Aggregation-prone |
| 29 | T | A | 0.0000 | Buried |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.0356 | Aggregation-prone |
| 36 | N | A | -0.3442 | Soluble |
| 37 | Y | A | 0.0000 | Buried |
| 38 | Y | A | -0.0134 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | Y | A | -0.0066 | Soluble |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.6478 | Soluble |
| 44 | Q | A | -0.8416 | Soluble |
| 45 | A | A | -1.1343 | Soluble |
| 46 | P | A | -1.0539 | Soluble |
| 47 | G | A | -1.2278 | Soluble |
| 48 | Q | A | -1.8430 | Soluble |
| 49 | G | A | -1.2919 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.3272 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | G | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | N | A | -0.9271 | Soluble |
| 58 | P | A | -0.9179 | Soluble |
| 59 | S | A | -1.1287 | Soluble |
| 62 | N | A | -1.7424 | Soluble |
| 63 | G | A | -1.3937 | Soluble |
| 64 | G | A | -1.2259 | Soluble |
| 65 | T | A | -1.0136 | Soluble |
| 66 | N | A | -1.5834 | Soluble |
| 67 | F | A | -1.6570 | Soluble |
| 68 | N | A | 0.0000 | Buried |
| 69 | E | A | -3.4226 | Soluble |
| 70 | K | A | -3.3022 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | K | A | -3.6133 | Soluble |
| 74 | N | A | -3.0102 | Soluble |
| 75 | R | A | -2.1841 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -1.0999 | Soluble |
| 78 | L | A | 0.0000 | Buried |
| 79 | T | A | -0.3747 | Soluble |
| 80 | T | A | -0.8894 | Soluble |
| 81 | D | A | -1.1624 | Soluble |
| 82 | S | A | -1.0394 | Soluble |
| 83 | S | A | -0.6709 | Soluble |
| 84 | T | A | -0.7897 | Soluble |
| 85 | T | A | -0.7669 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.4767 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.5938 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | K | A | -2.1850 | Soluble |
| 93 | S | A | -1.5889 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -1.2808 | Soluble |
| 96 | F | A | 0.2125 | Aggregation-prone |
| 97 | D | A | -1.2172 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.3050 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2645 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | R | A | -0.2156 | Soluble |
| 108 | D | A | -0.4068 | Soluble |
| 109 | Y | A | -0.1674 | Soluble |
| 110 | R | A | -1.2273 | Soluble |
| 111 | F | A | 0.0140 | Aggregation-prone |
| 112 | D | A | -0.0656 | Soluble |
| 113 | M | A | 0.2168 | Aggregation-prone |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.4294 | Soluble |
| 117 | Y | A | 0.0238 | Aggregation-prone |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3992 | Soluble |
| 121 | G | A | -0.5594 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | T | A | 0.4785 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | 0.0000 | Buried |
| 128 | S | A | -0.6197 | Soluble |
| 129 | A | A | -0.6344 | Soluble |
| 130 | S | A | -0.7794 | Soluble |
| 131 | T | A | -0.8533 | Soluble |
| 132 | K | A | -1.7553 | Soluble |
| 133 | G | A | -1.6851 | Soluble |
| 134 | P | A | -0.8218 | Soluble |
| 135 | S | A | -0.4647 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1161 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8799 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.7566 | Soluble |
| 143 | S | A | -0.7268 | Soluble |
| 144 | K | A | -1.1130 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.7092 | Soluble |
| 147 | S | A | -0.6976 | Soluble |
| 148 | G | A | -0.8105 | Soluble |
| 149 | G | A | -0.8737 | Soluble |
| 150 | T | A | -0.5890 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.8246 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.7695 | Soluble |
| 164 | P | A | -0.8988 | Soluble |
| 165 | V | A | -0.6980 | Soluble |
| 166 | T | A | -0.5197 | Soluble |
| 167 | V | A | -0.3209 | Soluble |
| 168 | S | A | -0.3708 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.8782 | Soluble |
| 171 | S | A | -0.7029 | Soluble |
| 172 | G | A | -0.4835 | Soluble |
| 173 | A | A | -0.2593 | Soluble |
| 174 | L | A | -0.0438 | Soluble |
| 175 | T | A | -0.1876 | Soluble |
| 176 | S | A | -0.2006 | Soluble |
| 177 | G | A | -0.2240 | Soluble |
| 178 | V | A | 0.1339 | Aggregation-prone |
| 179 | H | A | -0.2579 | Soluble |
| 180 | T | A | 0.0622 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3818 | Soluble |
| 183 | A | A | 0.1584 | Aggregation-prone |
| 184 | V | A | 0.4535 | Aggregation-prone |
| 185 | L | A | 0.9325 | Aggregation-prone |
| 186 | Q | A | 0.0110 | Aggregation-prone |
| 187 | S | A | -0.2362 | Soluble |
| 188 | S | A | -0.2619 | Soluble |
| 189 | G | A | 0.1620 | Aggregation-prone |
| 190 | L | A | -0.1892 | Soluble |
| 191 | Y | A | 0.1145 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1339 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5216 | Soluble |
| 201 | S | A | -0.5727 | Soluble |
| 202 | S | A | -0.6072 | Soluble |
| 203 | S | A | 0.0000 | Buried |
| 204 | L | A | -0.8395 | Soluble |
| 205 | G | A | -1.0342 | Soluble |
| 206 | T | A | -0.8626 | Soluble |
| 207 | Q | A | -1.4858 | Soluble |
| 208 | T | A | -1.2593 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.3278 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4582 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.7832 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7438 | Soluble |
| 217 | P | A | -1.8065 | Soluble |
| 218 | S | A | -1.9702 | Soluble |
| 219 | N | A | -2.5793 | Soluble |
| 220 | T | A | -2.1453 | Soluble |
| 221 | K | A | -2.6245 | Soluble |
| 222 | V | A | -1.6327 | Soluble |
| 223 | D | A | -2.5370 | Soluble |
| 224 | K | A | -1.9980 | Soluble |
| 225 | K | A | -2.5286 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.4905 | Soluble |
| 228 | P | A | -1.1929 | Soluble |
| 1 | E | B | -1.8160 | Soluble |
| 2 | I | B | -0.8931 | Soluble |
| 3 | V | B | 0.2772 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.7563 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6949 | Soluble |
| 8 | P | B | -0.3294 | Soluble |
| 9 | A | B | -0.3472 | Soluble |
| 10 | T | B | -0.2823 | Soluble |
| 11 | L | B | -0.1647 | Soluble |
| 12 | S | B | -0.5524 | Soluble |
| 13 | L | B | -1.0645 | Soluble |
| 14 | S | B | -1.4835 | Soluble |
| 15 | P | B | -1.8145 | Soluble |
| 16 | G | B | -1.9356 | Soluble |
| 17 | E | B | -2.5587 | Soluble |
| 18 | R | B | -2.8011 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6781 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -1.0338 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.7354 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.3666 | Soluble |
| 27 | K | B | -2.3741 | Soluble |
| 28 | G | B | -1.7522 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.5735 | Soluble |
| 31 | T | B | -0.2908 | Soluble |
| 34 | S | B | -0.2632 | Soluble |
| 35 | G | B | -0.3080 | Soluble |
| 36 | Y | B | 0.2050 | Aggregation-prone |
| 37 | S | B | 0.0000 | Buried |
| 38 | Y | B | -0.2796 | Soluble |
| 39 | L | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | -0.7715 | Soluble |
| 44 | Q | B | -1.1302 | Soluble |
| 45 | K | B | -1.6254 | Soluble |
| 46 | P | B | -1.3819 | Soluble |
| 47 | G | B | -1.4584 | Soluble |
| 48 | Q | B | -2.1318 | Soluble |
| 49 | A | B | -1.3598 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.1905 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.5889 | Aggregation-prone |
| 56 | L | B | 0.0000 | Buried |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | 0.2720 | Aggregation-prone |
| 66 | Y | B | 0.9831 | Aggregation-prone |
| 67 | L | B | 0.7959 | Aggregation-prone |
| 68 | E | B | -0.0003 | Soluble |
| 69 | S | B | -0.2868 | Soluble |
| 70 | G | B | -0.4753 | Soluble |
| 71 | V | B | -0.2517 | Soluble |
| 72 | P | B | -0.2154 | Soluble |
| 74 | A | B | -0.1659 | Soluble |
| 75 | R | B | -0.7129 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0825 | Soluble |
| 78 | G | B | -0.0451 | Soluble |
| 79 | S | B | -0.6340 | Soluble |
| 80 | G | B | -1.3101 | Soluble |
| 83 | S | B | -1.1895 | Soluble |
| 84 | G | B | -1.4404 | Soluble |
| 85 | T | B | -2.2277 | Soluble |
| 86 | D | B | -2.9391 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.9355 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6388 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.5299 | Soluble |
| 93 | S | B | -1.9274 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.4301 | Soluble |
| 96 | P | B | -1.6768 | Soluble |
| 97 | E | B | -2.3329 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.6839 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.4307 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | H | B | 0.0000 | Buried |
| 107 | S | B | -0.8400 | Soluble |
| 108 | R | B | -1.9342 | Soluble |
| 109 | D | B | -2.1175 | Soluble |
| 114 | L | B | -1.0274 | Soluble |
| 115 | P | B | -1.2081 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.4636 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.8010 | Soluble |
| 121 | G | B | -0.7248 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.8577 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.6633 | Soluble |
| 127 | K | B | -1.5346 | Soluble |
| 128 | R | B | -1.0434 | Soluble |
| 129 | T | B | 0.0215 | Aggregation-prone |
| 130 | V | B | 0.8907 | Aggregation-prone |
| 131 | A | B | 0.3406 | Aggregation-prone |
| 132 | A | B | 0.0193 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1651 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.9015 | Soluble |
| 140 | P | B | -0.8424 | Soluble |
| 141 | S | B | -1.6184 | Soluble |
| 142 | D | B | -2.9112 | Soluble |
| 143 | E | B | -2.9283 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.2245 | Soluble |
| 146 | K | B | -2.7698 | Soluble |
| 147 | S | B | -1.7337 | Soluble |
| 148 | G | B | -1.3593 | Soluble |
| 149 | T | B | -1.0013 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.6905 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -0.9969 | Soluble |
| 162 | R | B | -1.5428 | Soluble |
| 163 | E | B | -2.6047 | Soluble |
| 164 | A | B | -2.0688 | Soluble |
| 165 | K | B | -2.4853 | Soluble |
| 166 | V | B | 0.0000 | Buried |
| 167 | Q | B | -0.9784 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.9248 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -2.0801 | Soluble |
| 172 | N | B | -1.5499 | Soluble |
| 173 | A | B | -0.5624 | Soluble |
| 174 | L | B | 0.0988 | Aggregation-prone |
| 175 | Q | B | -0.6387 | Soluble |
| 176 | S | B | -0.8825 | Soluble |
| 177 | G | B | -1.3477 | Soluble |
| 178 | N | B | -1.7735 | Soluble |
| 179 | S | B | -1.5043 | Soluble |
| 180 | Q | B | -1.3708 | Soluble |
| 181 | E | B | -1.4393 | Soluble |
| 182 | S | B | -0.4666 | Soluble |
| 183 | V | B | -0.2653 | Soluble |
| 184 | T | B | -0.8966 | Soluble |
| 185 | E | B | -2.0548 | Soluble |
| 186 | Q | B | -1.6462 | Soluble |
| 187 | D | B | -1.8984 | Soluble |
| 188 | S | B | -1.6804 | Soluble |
| 189 | K | B | -2.2614 | Soluble |
| 190 | D | B | -1.7219 | Soluble |
| 191 | S | B | -1.6983 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6801 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6976 | Soluble |
| 201 | L | B | -0.8713 | Soluble |
| 202 | S | B | -1.0141 | Soluble |
| 203 | K | B | -1.8878 | Soluble |
| 204 | A | B | -1.8612 | Soluble |
| 205 | D | B | -2.6732 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4874 | Soluble |
| 208 | K | B | -3.6626 | Soluble |
| 209 | H | B | -3.0439 | Soluble |
| 210 | K | B | -3.1606 | Soluble |
| 211 | V | B | -1.6659 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.9114 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.3531 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.4909 | Soluble |
| 220 | G | B | -0.3135 | Soluble |
| 221 | L | B | -0.2219 | Soluble |
| 222 | S | B | -0.4686 | Soluble |
| 223 | S | B | -0.4577 | Soluble |
| 224 | P | B | -0.6838 | Soluble |
| 225 | V | B | -0.0276 | Soluble |
| 226 | T | B | -0.4453 | Soluble |
| 227 | K | B | -0.7123 | Soluble |
| 228 | S | B | -0.6119 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -2.0799 | Soluble |
| 231 | R | B | -2.6287 | Soluble |
| 232 | G | B | -2.1833 | Soluble |
| 233 | E | B | -2.5564 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6441 | 3.2153 | CSV PDB |
| 4.5 | -0.6893 | 3.0273 | CSV PDB |
| 5.0 | -0.743 | 2.8313 | CSV PDB |
| 5.5 | -0.7944 | 2.6427 | CSV PDB |
| 6.0 | -0.8311 | 2.4695 | CSV PDB |
| 6.5 | -0.8427 | 2.3104 | CSV PDB |
| 7.0 | -0.8283 | 2.1617 | CSV PDB |
| 7.5 | -0.7967 | 2.0227 | CSV PDB |
| 8.0 | -0.7557 | 1.9016 | CSV PDB |
| 8.5 | -0.7085 | 1.8178 | CSV PDB |
| 9.0 | -0.6555 | 1.7893 | CSV PDB |