Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLEQPGGSLRLSCAGSGFTFRDYAMTWVRQAPGKGLEWVSSISGSGGNTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRLSITIRPRYYGLDVWGQGTTVTVSSASTKGPSVFPLAPCESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGKTYTCNVDHKPSNTKVDKRVEDIVMTQSPLSLPVTPGEPASISCRSSQSLLYSIGYNYLDWYLQKSGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGFYYCMQALQTPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1034 | Soluble |
| 2 | V | A | -1.2508 | Soluble |
| 3 | Q | A | -1.2816 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.1164 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.3565 | Soluble |
| 8 | G | A | -0.9803 | Soluble |
| 9 | G | A | -0.8122 | Soluble |
| 11 | G | A | -0.9478 | Soluble |
| 12 | L | A | -0.6591 | Soluble |
| 13 | E | A | -1.3003 | Soluble |
| 14 | Q | A | -1.8833 | Soluble |
| 15 | P | A | -1.7290 | Soluble |
| 16 | G | A | -1.4365 | Soluble |
| 17 | G | A | -1.2398 | Soluble |
| 18 | S | A | -1.2465 | Soluble |
| 19 | L | A | -0.9339 | Soluble |
| 20 | R | A | -1.6748 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.2763 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.2205 | Soluble |
| 25 | G | A | 0.0000 | Buried |
| 26 | S | A | -0.8322 | Soluble |
| 27 | G | A | -1.2108 | Soluble |
| 28 | F | A | -0.7538 | Soluble |
| 29 | T | A | -0.7427 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | R | A | -2.0351 | Soluble |
| 36 | D | A | -0.5106 | Soluble |
| 37 | Y | A | -0.3403 | Soluble |
| 38 | A | A | 0.0000 | Buried |
| 39 | M | A | 0.0000 | Buried |
| 40 | T | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.9536 | Soluble |
| 45 | A | A | -1.2762 | Soluble |
| 46 | P | A | -1.0570 | Soluble |
| 47 | G | A | -1.4746 | Soluble |
| 48 | K | A | -2.4526 | Soluble |
| 49 | G | A | -1.6272 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.4549 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | S | A | 0.0000 | Buried |
| 55 | S | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | -0.9514 | Soluble |
| 58 | G | A | 0.0000 | Buried |
| 59 | S | A | -1.1290 | Soluble |
| 62 | G | A | -1.3482 | Soluble |
| 63 | G | A | -1.2570 | Soluble |
| 64 | N | A | -1.5004 | Soluble |
| 65 | T | A | -0.4870 | Soluble |
| 66 | Y | A | -0.0305 | Soluble |
| 67 | Y | A | -0.5132 | Soluble |
| 68 | A | A | -1.2489 | Soluble |
| 69 | D | A | -2.3430 | Soluble |
| 70 | S | A | -1.7649 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.4885 | Soluble |
| 74 | G | A | -1.7519 | Soluble |
| 75 | R | A | -1.5323 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.7394 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.6126 | Soluble |
| 80 | R | A | -1.2805 | Soluble |
| 81 | D | A | -1.9149 | Soluble |
| 82 | N | A | -2.2653 | Soluble |
| 83 | S | A | -1.8699 | Soluble |
| 84 | K | A | -2.4160 | Soluble |
| 85 | N | A | -2.1635 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.5218 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.0717 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.4867 | Soluble |
| 93 | S | A | -1.2287 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.1991 | Soluble |
| 96 | A | A | -1.6755 | Soluble |
| 97 | E | A | -2.1776 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7747 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1941 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | K | A | 0.0000 | Buried |
| 107 | D | A | 0.0000 | Buried |
| 108 | R | A | -0.3980 | Soluble |
| 109 | L | A | -0.1069 | Soluble |
| 110 | S | A | 0.4434 | Aggregation-prone |
| 111 | I | A | 1.7805 | Aggregation-prone |
| 111A | T | A | 1.3158 | Aggregation-prone |
| 111B | I | A | 1.7157 | Aggregation-prone |
| 112C | R | A | -0.1926 | Soluble |
| 112B | P | A | -0.2441 | Soluble |
| 112A | R | A | -0.8484 | Soluble |
| 112 | Y | A | 0.0000 | Buried |
| 113 | Y | A | -0.0905 | Soluble |
| 114 | G | A | 0.0000 | Buried |
| 115 | L | A | 0.0000 | Buried |
| 116 | D | A | -0.4869 | Soluble |
| 117 | V | A | -0.4501 | Soluble |
| 118 | W | A | -0.2754 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.1285 | Soluble |
| 121 | G | A | -0.4438 | Soluble |
| 122 | T | A | -0.2977 | Soluble |
| 123 | T | A | -0.2649 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.7068 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0728 | Soluble |
| 128 | S | A | -0.7633 | Soluble |
| 129 | A | A | -0.5513 | Soluble |
| 130 | S | A | -0.6588 | Soluble |
| 131 | T | A | -0.8232 | Soluble |
| 132 | K | A | -1.1317 | Soluble |
| 133 | G | A | -1.4095 | Soluble |
| 134 | P | A | -0.6231 | Soluble |
| 135 | S | A | -0.2540 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.5790 | Soluble |
| 138 | P | A | -1.0628 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.2688 | Soluble |
| 141 | P | A | 0.0081 | Aggregation-prone |
| 142 | C | A | 0.0790 | Aggregation-prone |
| 143 | E | A | -2.0014 | Soluble |
| 144 | S | A | -1.2297 | Soluble |
| 145 | T | A | -0.8506 | Soluble |
| 146 | A | A | -0.5240 | Soluble |
| 147 | A | A | 0.0000 | Buried |
| 148 | L | A | 0.0000 | Buried |
| 149 | G | A | 0.0000 | Buried |
| 150 | C | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | K | A | 0.0000 | Buried |
| 154 | D | A | -0.3540 | Soluble |
| 155 | Y | A | 0.0000 | Buried |
| 156 | F | A | -0.2578 | Soluble |
| 157 | P | A | 0.0000 | Buried |
| 158 | E | A | -0.6382 | Soluble |
| 159 | P | A | -0.7607 | Soluble |
| 160 | V | A | 0.0000 | Buried |
| 161 | T | A | -0.6792 | Soluble |
| 162 | V | A | -0.3302 | Soluble |
| 163 | S | A | -0.3964 | Soluble |
| 164 | W | A | 0.0000 | Buried |
| 165 | N | A | -0.9435 | Soluble |
| 166 | S | A | -0.6940 | Soluble |
| 167 | G | A | -0.6201 | Soluble |
| 168 | A | A | -0.2857 | Soluble |
| 169 | L | A | -0.0888 | Soluble |
| 170 | T | A | -0.1900 | Soluble |
| 171 | S | A | -0.1932 | Soluble |
| 172 | G | A | -0.2341 | Soluble |
| 173 | V | A | 0.1814 | Aggregation-prone |
| 174 | H | A | -0.1343 | Soluble |
| 175 | T | A | -0.0079 | Soluble |
| 176 | F | A | 0.0000 | Buried |
| 177 | P | A | -0.3937 | Soluble |
| 178 | A | A | 0.0229 | Aggregation-prone |
| 179 | V | A | 0.3390 | Aggregation-prone |
| 180 | L | A | 1.1768 | Aggregation-prone |
| 181 | Q | A | 0.2797 | Aggregation-prone |
| 182 | S | A | -0.0760 | Soluble |
| 183 | S | A | -0.2221 | Soluble |
| 184 | G | A | 0.0322 | Aggregation-prone |
| 185 | L | A | 0.1842 | Aggregation-prone |
| 186 | Y | A | 0.4454 | Aggregation-prone |
| 187 | S | A | 0.0000 | Buried |
| 188 | L | A | 0.0000 | Buried |
| 189 | S | A | 0.0000 | Buried |
| 190 | S | A | 0.0000 | Buried |
| 191 | V | A | 0.0000 | Buried |
| 192 | V | A | 0.0000 | Buried |
| 193 | T | A | -0.1086 | Soluble |
| 194 | V | A | 0.0000 | Buried |
| 195 | P | A | -0.6357 | Soluble |
| 196 | S | A | -0.7597 | Soluble |
| 197 | S | A | -0.6577 | Soluble |
| 198 | S | A | -0.5235 | Soluble |
| 199 | L | A | -0.4466 | Soluble |
| 200 | G | A | -0.8405 | Soluble |
| 201 | K | A | -1.8712 | Soluble |
| 202 | T | A | -1.5973 | Soluble |
| 203 | Y | A | 0.0000 | Buried |
| 204 | T | A | 0.0000 | Buried |
| 205 | C | A | 0.0000 | Buried |
| 206 | N | A | -1.3085 | Soluble |
| 207 | V | A | 0.0000 | Buried |
| 208 | D | A | -1.8702 | Soluble |
| 209 | H | A | 0.0000 | Buried |
| 210 | K | A | -2.7917 | Soluble |
| 211 | P | A | -1.6452 | Soluble |
| 212 | S | A | -1.7990 | Soluble |
| 213 | N | A | -2.4409 | Soluble |
| 214 | T | A | -2.1070 | Soluble |
| 215 | K | A | -2.5282 | Soluble |
| 216 | V | A | -1.2597 | Soluble |
| 217 | D | A | -1.7335 | Soluble |
| 218 | K | A | -1.8902 | Soluble |
| 219 | R | A | -2.6476 | Soluble |
| 220 | V | A | 0.0000 | Buried |
| 221 | E | A | -2.4797 | Soluble |
| 1 | D | B | -1.6860 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.6865 | Aggregation-prone |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -0.5540 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.4109 | Soluble |
| 8 | P | B | 0.0014 | Aggregation-prone |
| 9 | L | B | 0.5907 | Aggregation-prone |
| 10 | S | B | 0.1930 | Aggregation-prone |
| 11 | L | B | -0.0467 | Soluble |
| 12 | P | B | -0.6943 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | T | B | -1.7397 | Soluble |
| 15 | P | B | -1.9307 | Soluble |
| 16 | G | B | -2.1339 | Soluble |
| 17 | E | B | -2.6085 | Soluble |
| 18 | P | B | -2.1730 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | S | B | -0.7187 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | S | B | -0.9723 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2224 | Soluble |
| 25 | S | B | 0.0000 | Buried |
| 26 | S | B | -0.9762 | Soluble |
| 27 | Q | B | -1.5364 | Soluble |
| 28 | S | B | -0.7667 | Soluble |
| 29 | L | B | 0.0000 | Buried |
| 30 | L | B | 1.5926 | Aggregation-prone |
| 31 | Y | B | 2.1286 | Aggregation-prone |
| 32 | S | B | 1.7515 | Aggregation-prone |
| 34 | I | B | 2.2927 | Aggregation-prone |
| 35 | G | B | 1.0492 | Aggregation-prone |
| 36 | Y | B | 1.5743 | Aggregation-prone |
| 37 | N | B | 0.0000 | Buried |
| 38 | Y | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | D | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | L | B | 0.0000 | Buried |
| 44 | Q | B | -0.6496 | Soluble |
| 45 | K | B | -1.3848 | Soluble |
| 46 | S | B | -1.2467 | Soluble |
| 47 | G | B | -1.5500 | Soluble |
| 48 | Q | B | -1.9807 | Soluble |
| 49 | S | B | -1.2704 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | Q | B | -1.0030 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.2061 | Soluble |
| 56 | L | B | 0.0000 | Buried |
| 57 | G | B | 0.0000 | Buried |
| 65 | S | B | -0.8430 | Soluble |
| 66 | N | B | -1.2019 | Soluble |
| 67 | R | B | -1.8683 | Soluble |
| 68 | A | B | -1.0211 | Soluble |
| 69 | S | B | -0.8055 | Soluble |
| 70 | G | B | -0.9034 | Soluble |
| 71 | V | B | -1.0735 | Soluble |
| 72 | P | B | -1.3245 | Soluble |
| 74 | D | B | -2.3924 | Soluble |
| 75 | R | B | -1.9450 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.3161 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.7823 | Soluble |
| 80 | G | B | -1.0925 | Soluble |
| 83 | S | B | -0.6235 | Soluble |
| 84 | G | B | -0.6467 | Soluble |
| 85 | T | B | -1.6578 | Soluble |
| 86 | D | B | -2.3750 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -1.0585 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | K | B | -1.4772 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.2292 | Soluble |
| 93 | R | B | -3.2741 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.5807 | Soluble |
| 96 | A | B | -2.4043 | Soluble |
| 97 | E | B | -2.8093 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | V | B | 0.0000 | Buried |
| 100 | G | B | 0.0000 | Buried |
| 101 | F | B | 0.4543 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | M | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | A | B | 0.0000 | Buried |
| 108 | L | B | 0.0074 | Aggregation-prone |
| 109 | Q | B | -1.2648 | Soluble |
| 114 | T | B | -0.6856 | Soluble |
| 115 | P | B | -1.0086 | Soluble |
| 116 | Y | B | 0.0000 | Buried |
| 117 | T | B | -0.3639 | Soluble |
| 118 | F | B | -0.0905 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.0751 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.2377 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -0.9528 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.4846 | Soluble |
| 128 | R | B | -1.0016 | Soluble |
| 129 | T | B | 0.2410 | Aggregation-prone |
| 130 | V | B | 1.2860 | Aggregation-prone |
| 131 | A | B | 0.7094 | Aggregation-prone |
| 132 | A | B | 0.3399 | Aggregation-prone |
| 133 | P | B | 0.1259 | Aggregation-prone |
| 134 | S | B | -0.0552 | Soluble |
| 135 | V | B | 0.0889 | Aggregation-prone |
| 136 | F | B | 0.1336 | Aggregation-prone |
| 137 | I | B | 0.1526 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.2312 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.3362 | Soluble |
| 142 | D | B | -2.6748 | Soluble |
| 143 | E | B | -2.4926 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1340 | Soluble |
| 146 | K | B | -2.6484 | Soluble |
| 147 | S | B | -1.6096 | Soluble |
| 148 | G | B | -1.1775 | Soluble |
| 149 | T | B | -0.9848 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8163 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | -0.6056 | Soluble |
| 161 | P | B | -1.3115 | Soluble |
| 162 | R | B | -2.8772 | Soluble |
| 163 | E | B | -3.1559 | Soluble |
| 164 | A | B | -2.2521 | Soluble |
| 165 | K | B | -2.3493 | Soluble |
| 166 | V | B | -0.9723 | Soluble |
| 167 | Q | B | -0.3908 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.4412 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.6513 | Soluble |
| 172 | N | B | -1.4054 | Soluble |
| 173 | A | B | -0.1864 | Soluble |
| 174 | L | B | 0.8347 | Aggregation-prone |
| 175 | Q | B | -0.1853 | Soluble |
| 176 | S | B | -0.6583 | Soluble |
| 177 | G | B | -1.2369 | Soluble |
| 178 | N | B | -1.5062 | Soluble |
| 179 | S | B | -1.4647 | Soluble |
| 180 | Q | B | -1.5704 | Soluble |
| 181 | E | B | -1.9958 | Soluble |
| 182 | S | B | -1.0449 | Soluble |
| 183 | V | B | -0.8325 | Soluble |
| 184 | T | B | -0.9940 | Soluble |
| 185 | E | B | -1.8252 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.1653 | Soluble |
| 188 | S | B | -2.4635 | Soluble |
| 189 | K | B | -2.7880 | Soluble |
| 190 | D | B | -1.9134 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7687 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6579 | Soluble |
| 201 | L | B | -0.8575 | Soluble |
| 202 | S | B | -1.1175 | Soluble |
| 203 | K | B | -2.1835 | Soluble |
| 204 | A | B | -1.9794 | Soluble |
| 205 | D | B | -2.6395 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4620 | Soluble |
| 208 | K | B | -3.5598 | Soluble |
| 209 | H | B | -2.7525 | Soluble |
| 210 | K | B | -2.6876 | Soluble |
| 211 | V | B | -0.9646 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6974 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0321 | Soluble |
| 218 | Q | B | -1.0647 | Soluble |
| 219 | G | B | -1.0192 | Soluble |
| 220 | T | B | -0.4101 | Soluble |
| 221 | T | B | -0.2573 | Soluble |
| 222 | S | B | -0.3657 | Soluble |
| 223 | V | B | 0.1352 | Aggregation-prone |
| 224 | T | B | -0.3300 | Soluble |
| 225 | K | B | -0.6874 | Soluble |
| 226 | S | B | -0.4235 | Soluble |
| 227 | F | B | 0.0000 | Buried |
| 228 | N | B | -1.4510 | Soluble |
| 229 | R | B | -2.0921 | Soluble |
| 230 | G | B | -2.0011 | Soluble |
| 231 | E | B | -2.2781 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6699 | 3.0401 | CSV PDB |
| 4.5 | -0.7158 | 3.0401 | CSV PDB |
| 5.0 | -0.7712 | 3.0401 | CSV PDB |
| 5.5 | -0.8258 | 3.0401 | CSV PDB |
| 6.0 | -0.8684 | 3.0401 | CSV PDB |
| 6.5 | -0.8892 | 3.0401 | CSV PDB |
| 7.0 | -0.8867 | 3.0401 | CSV PDB |
| 7.5 | -0.8683 | 3.04 | CSV PDB |
| 8.0 | -0.8413 | 3.0398 | CSV PDB |
| 8.5 | -0.8083 | 3.0392 | CSV PDB |
| 9.0 | -0.7692 | 3.0371 | CSV PDB |