Calculation Parameters
| Chain Sequence(s) |
QVQLKQSGPGLVQPGGSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSDIQMTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.3987 | Soluble |
| 2 | V | B | -0.7435 | Soluble |
| 3 | Q | B | -1.5026 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | K | B | -2.3048 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8366 | Soluble |
| 8 | G | B | -1.1633 | Soluble |
| 9 | P | B | -0.5368 | Soluble |
| 11 | G | B | -0.4623 | Soluble |
| 12 | L | B | 0.0027 | Aggregation-prone |
| 13 | V | B | -0.5197 | Soluble |
| 14 | Q | B | -1.2049 | Soluble |
| 15 | P | B | -1.5498 | Soluble |
| 16 | G | B | -1.5122 | Soluble |
| 17 | G | B | -1.2976 | Soluble |
| 18 | S | B | -1.4988 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | S | B | -0.7239 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.5822 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | T | B | -1.1716 | Soluble |
| 25 | V | B | 0.0000 | Buried |
| 26 | S | B | -1.1423 | Soluble |
| 27 | G | B | -0.8993 | Soluble |
| 28 | F | B | -0.4969 | Soluble |
| 29 | S | B | -0.8808 | Soluble |
| 30 | L | B | 0.0000 | Buried |
| 35 | T | B | -0.8868 | Soluble |
| 36 | N | B | -0.8462 | Soluble |
| 37 | Y | B | 0.4339 | Aggregation-prone |
| 38 | G | B | 0.0000 | Buried |
| 39 | V | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.5031 | Soluble |
| 45 | S | B | -0.9853 | Soluble |
| 46 | P | B | -0.9500 | Soluble |
| 47 | G | B | -1.6680 | Soluble |
| 48 | K | B | -2.3241 | Soluble |
| 49 | G | B | -1.2298 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.6842 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | V | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | W | B | -0.5237 | Soluble |
| 58 | S | B | -0.6047 | Soluble |
| 59 | G | B | -1.2157 | Soluble |
| 63 | G | B | -1.4895 | Soluble |
| 64 | N | B | -1.8428 | Soluble |
| 65 | T | B | -1.3041 | Soluble |
| 66 | D | B | -1.0068 | Soluble |
| 67 | Y | B | -0.3428 | Soluble |
| 68 | N | B | 0.0000 | Buried |
| 69 | T | B | -0.2013 | Soluble |
| 70 | P | B | -0.3534 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | T | B | -0.4401 | Soluble |
| 74 | S | B | -0.6738 | Soluble |
| 75 | R | B | -1.2201 | Soluble |
| 76 | L | B | 0.0000 | Buried |
| 77 | S | B | -1.0863 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | N | B | -1.7722 | Soluble |
| 80 | K | B | -1.4401 | Soluble |
| 81 | D | B | -1.7412 | Soluble |
| 82 | N | B | -2.1122 | Soluble |
| 83 | S | B | -1.6294 | Soluble |
| 84 | K | B | -2.3215 | Soluble |
| 85 | S | B | -1.5546 | Soluble |
| 86 | Q | B | -1.5326 | Soluble |
| 87 | V | B | 0.0000 | Buried |
| 88 | F | B | -0.4246 | Soluble |
| 89 | F | B | 0.0000 | Buried |
| 90 | K | B | -1.5317 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.1657 | Soluble |
| 93 | S | B | -1.6274 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -2.2366 | Soluble |
| 96 | S | B | -1.6019 | Soluble |
| 97 | N | B | -2.0883 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.5604 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | I | B | 0.6123 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | A | B | 0.0000 | Buried |
| 108 | L | B | 1.0977 | Aggregation-prone |
| 109 | T | B | 1.1489 | Aggregation-prone |
| 110 | Y | B | 1.8331 | Aggregation-prone |
| 111 | Y | B | 1.8901 | Aggregation-prone |
| 112 | D | B | 1.0010 | Aggregation-prone |
| 113 | Y | B | 0.5424 | Aggregation-prone |
| 114 | E | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | A | B | 0.3159 | Aggregation-prone |
| 117 | Y | B | 0.2849 | Aggregation-prone |
| 118 | W | B | -0.4443 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8035 | Soluble |
| 121 | G | B | -0.8770 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.2637 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.2777 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.7155 | Soluble |
| 128 | A | B | -0.4604 | Soluble |
| 129 | A | B | -0.2769 | Soluble |
| 130 | S | B | -0.4481 | Soluble |
| 131 | T | B | -0.7038 | Soluble |
| 132 | K | B | -1.2058 | Soluble |
| 133 | G | B | -1.3220 | Soluble |
| 134 | P | B | -0.5885 | Soluble |
| 135 | S | B | -0.2381 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1067 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.1841 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.2315 | Soluble |
| 143 | S | B | -1.3400 | Soluble |
| 144 | K | B | -1.9248 | Soluble |
| 145 | S | B | -1.1304 | Soluble |
| 146 | T | B | -0.9547 | Soluble |
| 147 | S | B | -0.9010 | Soluble |
| 148 | G | B | -0.8576 | Soluble |
| 149 | G | B | -0.9223 | Soluble |
| 150 | T | B | -0.6194 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.3892 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.3702 | Soluble |
| 164 | P | B | -0.5875 | Soluble |
| 165 | V | B | -0.6259 | Soluble |
| 166 | T | B | -0.5617 | Soluble |
| 167 | V | B | -0.4028 | Soluble |
| 168 | S | B | -0.3964 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.7290 | Soluble |
| 171 | S | B | -0.6475 | Soluble |
| 172 | G | B | -0.5634 | Soluble |
| 173 | A | B | -0.2366 | Soluble |
| 174 | L | B | 0.0049 | Aggregation-prone |
| 175 | T | B | -0.1840 | Soluble |
| 176 | S | B | -0.1966 | Soluble |
| 177 | G | B | -0.2428 | Soluble |
| 178 | V | B | 0.1457 | Aggregation-prone |
| 179 | H | B | -0.2721 | Soluble |
| 180 | T | B | 0.0416 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.2732 | Soluble |
| 183 | A | B | 0.2328 | Aggregation-prone |
| 184 | V | B | 0.4273 | Aggregation-prone |
| 185 | L | B | 1.1421 | Aggregation-prone |
| 186 | Q | B | 0.2758 | Aggregation-prone |
| 187 | S | B | -0.0663 | Soluble |
| 188 | S | B | -0.2205 | Soluble |
| 189 | G | B | 0.0133 | Aggregation-prone |
| 190 | L | B | 0.1328 | Aggregation-prone |
| 191 | Y | B | 0.4605 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1339 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6497 | Soluble |
| 201 | S | B | -0.6248 | Soluble |
| 202 | S | B | -0.5978 | Soluble |
| 203 | S | B | -0.6369 | Soluble |
| 204 | L | B | -0.7673 | Soluble |
| 205 | G | B | -0.9547 | Soluble |
| 206 | T | B | -0.7216 | Soluble |
| 207 | Q | B | -1.2719 | Soluble |
| 208 | T | B | -1.1299 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.1919 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.5158 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -1.9752 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8082 | Soluble |
| 217 | P | B | -1.6076 | Soluble |
| 218 | S | B | -1.8006 | Soluble |
| 219 | N | B | -2.5700 | Soluble |
| 220 | T | B | -2.0509 | Soluble |
| 221 | K | B | -2.6759 | Soluble |
| 222 | V | B | -1.4619 | Soluble |
| 223 | D | B | -2.6140 | Soluble |
| 224 | K | B | -2.1613 | Soluble |
| 225 | R | B | -2.7384 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.8875 | Soluble |
| 228 | P | B | -1.9504 | Soluble |
| 229 | K | B | -2.3718 | Soluble |
| 230 | S | B | -1.2948 | Soluble |
| 1 | D | A | -2.2357 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.0846 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.0182 | Soluble |
| 6 | Q | A | -0.3216 | Soluble |
| 7 | S | A | -0.0098 | Soluble |
| 8 | P | A | 0.6371 | Aggregation-prone |
| 9 | V | A | 1.7052 | Aggregation-prone |
| 10 | I | A | 1.1533 | Aggregation-prone |
| 11 | L | A | 0.4652 | Aggregation-prone |
| 12 | S | A | -0.2068 | Soluble |
| 13 | V | A | -1.0960 | Soluble |
| 14 | S | A | -1.7222 | Soluble |
| 15 | P | A | -2.0692 | Soluble |
| 16 | G | A | -2.3581 | Soluble |
| 17 | E | A | -3.0891 | Soluble |
| 18 | R | A | -3.1659 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | S | A | -0.8336 | Soluble |
| 21 | F | A | 0.0000 | Buried |
| 22 | S | A | -1.0176 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.6610 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.9652 | Soluble |
| 27 | Q | A | -2.4008 | Soluble |
| 28 | S | A | -1.6829 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | G | A | -1.0751 | Soluble |
| 37 | T | A | -0.7764 | Soluble |
| 38 | N | A | -0.8117 | Soluble |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -1.1709 | Soluble |
| 45 | R | A | -2.0067 | Soluble |
| 46 | T | A | -1.6898 | Soluble |
| 47 | N | A | -1.9819 | Soluble |
| 48 | G | A | -1.4844 | Soluble |
| 49 | S | A | -1.0309 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -0.6466 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | K | A | -0.7086 | Soluble |
| 56 | Y | A | -0.4626 | Soluble |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -1.1871 | Soluble |
| 66 | E | A | -1.8310 | Soluble |
| 67 | S | A | -1.1203 | Soluble |
| 68 | I | A | -0.4888 | Soluble |
| 69 | S | A | -0.3514 | Soluble |
| 70 | G | A | -0.4813 | Soluble |
| 71 | I | A | -0.2712 | Soluble |
| 72 | P | A | -0.4493 | Soluble |
| 74 | S | A | -0.6301 | Soluble |
| 75 | R | A | -1.1225 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.9146 | Soluble |
| 78 | G | A | -0.6934 | Soluble |
| 79 | S | A | -0.8666 | Soluble |
| 80 | G | A | -1.1435 | Soluble |
| 83 | S | A | -1.1830 | Soluble |
| 84 | G | A | -1.4304 | Soluble |
| 85 | T | A | -1.9843 | Soluble |
| 86 | D | A | -2.7235 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.8957 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | S | A | 0.0000 | Buried |
| 91 | I | A | 0.0000 | Buried |
| 92 | N | A | -2.6787 | Soluble |
| 93 | S | A | -2.5845 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | E | A | -2.9774 | Soluble |
| 96 | S | A | -2.5493 | Soluble |
| 97 | E | A | -2.7556 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | I | A | 0.0000 | Buried |
| 100 | A | A | -1.3792 | Soluble |
| 101 | D | A | -0.5831 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | N | A | -0.7573 | Soluble |
| 108 | N | A | -1.4881 | Soluble |
| 109 | N | A | -1.4591 | Soluble |
| 114 | W | A | -0.1693 | Soluble |
| 115 | P | A | -0.3904 | Soluble |
| 116 | T | A | 0.0000 | Buried |
| 117 | T | A | -0.6798 | Soluble |
| 118 | F | A | -0.1614 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | A | A | -0.3826 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.5111 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | L | A | 0.0000 | Buried |
| 127 | K | A | -1.3806 | Soluble |
| 128 | R | A | -1.0812 | Soluble |
| 129 | T | A | 0.0310 | Aggregation-prone |
| 130 | V | A | 0.7936 | Aggregation-prone |
| 131 | A | A | 0.1995 | Aggregation-prone |
| 132 | A | A | 0.0344 | Aggregation-prone |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1003 | Soluble |
| 135 | V | A | -0.0763 | Soluble |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.5101 | Soluble |
| 140 | P | A | 0.0000 | Buried |
| 141 | S | A | -1.4165 | Soluble |
| 142 | D | A | -2.6280 | Soluble |
| 143 | E | A | -2.3680 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.0204 | Soluble |
| 146 | K | A | -2.6138 | Soluble |
| 147 | S | A | -1.6150 | Soluble |
| 148 | G | A | -1.2982 | Soluble |
| 149 | T | A | -0.8492 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.7918 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.3408 | Soluble |
| 162 | R | A | -2.2386 | Soluble |
| 163 | E | A | -2.7588 | Soluble |
| 164 | A | A | -1.9327 | Soluble |
| 165 | K | A | -2.0530 | Soluble |
| 166 | V | A | -1.0519 | Soluble |
| 167 | Q | A | -0.6986 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.8282 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -2.1438 | Soluble |
| 172 | N | A | -1.6906 | Soluble |
| 173 | A | A | -0.5346 | Soluble |
| 174 | L | A | 0.1886 | Aggregation-prone |
| 175 | Q | A | -0.6276 | Soluble |
| 176 | S | A | -0.7277 | Soluble |
| 177 | G | A | -1.2096 | Soluble |
| 178 | N | A | -1.4487 | Soluble |
| 179 | S | A | -1.4570 | Soluble |
| 180 | Q | A | -1.4982 | Soluble |
| 181 | E | A | -1.8505 | Soluble |
| 182 | S | A | -0.8115 | Soluble |
| 183 | V | A | -0.4763 | Soluble |
| 184 | T | A | -0.9004 | Soluble |
| 185 | E | A | -2.2389 | Soluble |
| 186 | Q | A | -1.7005 | Soluble |
| 187 | D | A | -2.0215 | Soluble |
| 188 | S | A | -2.4284 | Soluble |
| 189 | K | A | -2.6449 | Soluble |
| 190 | D | A | -1.7732 | Soluble |
| 191 | S | A | 0.0000 | Buried |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.7644 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.6045 | Soluble |
| 201 | L | A | -0.8071 | Soluble |
| 202 | S | A | -1.0685 | Soluble |
| 203 | K | A | -1.9992 | Soluble |
| 204 | A | A | -1.8892 | Soluble |
| 205 | D | A | -2.6768 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.4469 | Soluble |
| 208 | K | A | -3.6392 | Soluble |
| 209 | H | A | -3.0457 | Soluble |
| 210 | K | A | -2.9205 | Soluble |
| 211 | V | A | -1.4617 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.7077 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.0950 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.5886 | Soluble |
| 220 | G | A | -0.3345 | Soluble |
| 221 | L | A | -0.1826 | Soluble |
| 222 | S | A | -0.4649 | Soluble |
| 223 | S | A | -0.4183 | Soluble |
| 224 | P | A | -0.5120 | Soluble |
| 225 | V | A | -0.0280 | Soluble |
| 226 | T | A | -0.4443 | Soluble |
| 227 | K | A | -0.7533 | Soluble |
| 228 | S | A | -0.6630 | Soluble |
| 229 | F | A | -0.8222 | Soluble |
| 230 | N | A | -1.4906 | Soluble |
| 231 | R | A | -1.8481 | Soluble |
| 232 | G | A | -1.1832 | Soluble |
| 233 | A | A | -0.6635 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7005 | 2.2748 | CSV PDB |
| 4.5 | -0.737 | 2.205 | CSV PDB |
| 5.0 | -0.781 | 2.1501 | CSV PDB |
| 5.5 | -0.8238 | 2.1359 | CSV PDB |
| 6.0 | -0.8548 | 2.1231 | CSV PDB |
| 6.5 | -0.8652 | 2.1102 | CSV PDB |
| 7.0 | -0.8539 | 2.0974 | CSV PDB |
| 7.5 | -0.8279 | 2.0847 | CSV PDB |
| 8.0 | -0.7938 | 2.0726 | CSV PDB |
| 8.5 | -0.7543 | 2.1537 | CSV PDB |
| 9.0 | -0.7094 | 2.2385 | CSV PDB |