Calculation Parameters
| Chain Sequence(s) |
VQLVESGGGLVQPGRSLRLSCAASGFTVHSSYYMAWVRQAPGKGLEWVGAIFTGSGAEYKAEWAKGRVTISKDTSKNQVVLTMTNMDPVDTATYYCASDAGYDYPTHAMHYWGQGTLVTVSSASTKGPSVFPLAPCSRSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYDIQMTQSPSSLSASVGDRVTITCRASQGISSSLAWYQQKPGKAPKLLIYGASETESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQNTKVGSSYGNTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | B | 0.5393 | Aggregation-prone |
| 3 | Q | B | -0.4016 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.8352 | Aggregation-prone |
| 6 | E | B | 0.1879 | Aggregation-prone |
| 7 | S | B | -0.3934 | Soluble |
| 8 | G | B | -0.9295 | Soluble |
| 9 | G | B | -0.2923 | Soluble |
| 11 | G | B | 0.7254 | Aggregation-prone |
| 12 | L | B | 1.3256 | Aggregation-prone |
| 13 | V | B | -0.6181 | Soluble |
| 14 | Q | B | -1.8092 | Soluble |
| 15 | P | B | -1.9615 | Soluble |
| 16 | G | B | -2.5703 | Soluble |
| 17 | R | B | -3.2651 | Soluble |
| 18 | S | B | -2.3695 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | R | B | -2.2366 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.5140 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.3288 | Soluble |
| 25 | A | B | -0.2460 | Soluble |
| 26 | S | B | -0.3994 | Soluble |
| 27 | G | B | -0.0786 | Soluble |
| 28 | F | B | 0.2935 | Aggregation-prone |
| 29 | T | B | 0.5648 | Aggregation-prone |
| 30 | V | B | 1.1301 | Aggregation-prone |
| 31 | H | B | -0.0106 | Soluble |
| 35 | S | B | 0.0790 | Aggregation-prone |
| 36 | S | B | 0.2455 | Aggregation-prone |
| 37 | Y | B | 0.0000 | Buried |
| 38 | Y | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | -0.5858 | Soluble |
| 44 | Q | B | -0.9096 | Soluble |
| 45 | A | B | -0.6466 | Soluble |
| 46 | P | B | -1.1000 | Soluble |
| 47 | G | B | -1.5193 | Soluble |
| 48 | K | B | -2.3062 | Soluble |
| 49 | G | B | -1.5113 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.1531 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | A | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | F | B | -0.1919 | Soluble |
| 58 | T | B | -0.5583 | Soluble |
| 59 | G | B | -0.6205 | Soluble |
| 62 | S | B | -0.5876 | Soluble |
| 63 | G | B | -0.7675 | Soluble |
| 64 | A | B | -0.5249 | Soluble |
| 65 | E | B | -0.9234 | Soluble |
| 66 | Y | B | -0.6605 | Soluble |
| 67 | K | B | -1.4841 | Soluble |
| 68 | A | B | 0.0000 | Buried |
| 69 | E | B | -2.6192 | Soluble |
| 70 | W | B | -1.3520 | Soluble |
| 71 | A | B | 0.0000 | Buried |
| 72 | K | B | -2.6267 | Soluble |
| 74 | G | B | -1.7556 | Soluble |
| 75 | R | B | -1.4536 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -0.8678 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.7211 | Soluble |
| 80 | K | B | -1.6527 | Soluble |
| 81 | D | B | -2.1492 | Soluble |
| 82 | T | B | -1.3556 | Soluble |
| 83 | S | B | -1.3263 | Soluble |
| 84 | K | B | -2.4771 | Soluble |
| 85 | N | B | -1.7218 | Soluble |
| 86 | Q | B | -1.3165 | Soluble |
| 87 | V | B | 0.0000 | Buried |
| 88 | V | B | -0.6777 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8594 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | T | B | -1.8856 | Soluble |
| 93 | N | B | -2.6763 | Soluble |
| 94 | M | B | 0.0000 | Buried |
| 95 | D | B | -1.4794 | Soluble |
| 96 | P | B | -0.1305 | Soluble |
| 97 | V | B | 1.2923 | Aggregation-prone |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | 0.5961 | Aggregation-prone |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | 0.1811 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | S | B | 0.0000 | Buried |
| 107 | D | B | 0.0000 | Buried |
| 108 | A | B | 0.1150 | Aggregation-prone |
| 109 | G | B | 0.0000 | Buried |
| 110 | Y | B | 0.3378 | Aggregation-prone |
| 111 | D | B | -1.0223 | Soluble |
| 111A | Y | B | -0.2449 | Soluble |
| 112A | P | B | -0.2473 | Soluble |
| 112 | T | B | -0.3327 | Soluble |
| 113 | H | B | -0.2660 | Soluble |
| 114 | A | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | H | B | -0.0706 | Soluble |
| 117 | Y | B | 0.1819 | Aggregation-prone |
| 118 | W | B | -0.1753 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.3000 | Soluble |
| 121 | G | B | -0.4957 | Soluble |
| 122 | T | B | 0.1923 | Aggregation-prone |
| 123 | L | B | 1.1185 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.2697 | Soluble |
| 128 | S | B | -0.6042 | Soluble |
| 129 | A | B | -0.4088 | Soluble |
| 130 | S | B | -0.6256 | Soluble |
| 131 | T | B | -0.9094 | Soluble |
| 132 | K | B | -1.6439 | Soluble |
| 133 | G | B | -1.6830 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4658 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | -0.6426 | Soluble |
| 138 | P | B | -1.1377 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.0086 | Soluble |
| 141 | P | B | -0.7093 | Soluble |
| 142 | C | B | -1.0304 | Soluble |
| 143 | S | B | -1.1852 | Soluble |
| 144 | R | B | -2.1230 | Soluble |
| 145 | S | B | -1.0383 | Soluble |
| 146 | G | B | -0.8455 | Soluble |
| 147 | G | B | -0.8524 | Soluble |
| 148 | T | B | -0.5197 | Soluble |
| 149 | A | B | 0.0000 | Buried |
| 150 | A | B | 0.0000 | Buried |
| 151 | L | B | 0.0000 | Buried |
| 152 | G | B | 0.0000 | Buried |
| 153 | C | B | 0.0000 | Buried |
| 154 | L | B | 0.0000 | Buried |
| 155 | V | B | 0.0000 | Buried |
| 156 | K | B | 0.0000 | Buried |
| 157 | D | B | -0.6272 | Soluble |
| 158 | Y | B | 0.0000 | Buried |
| 159 | F | B | 0.0000 | Buried |
| 160 | P | B | -0.8791 | Soluble |
| 161 | E | B | -1.2298 | Soluble |
| 162 | P | B | -1.1835 | Soluble |
| 163 | V | B | 0.0000 | Buried |
| 164 | T | B | -0.6364 | Soluble |
| 165 | V | B | -0.3468 | Soluble |
| 166 | S | B | -0.5244 | Soluble |
| 167 | W | B | 0.0000 | Buried |
| 168 | N | B | -0.9650 | Soluble |
| 169 | S | B | -0.7622 | Soluble |
| 170 | G | B | -0.5900 | Soluble |
| 171 | A | B | -0.2521 | Soluble |
| 172 | L | B | -0.0634 | Soluble |
| 173 | T | B | -0.1540 | Soluble |
| 174 | S | B | -0.2013 | Soluble |
| 175 | G | B | -0.2502 | Soluble |
| 176 | V | B | 0.1396 | Aggregation-prone |
| 177 | H | B | -0.3481 | Soluble |
| 178 | T | B | -0.0107 | Soluble |
| 179 | F | B | 0.0000 | Buried |
| 180 | P | B | -0.5933 | Soluble |
| 181 | A | B | 0.0026 | Aggregation-prone |
| 182 | V | B | 0.3363 | Aggregation-prone |
| 183 | L | B | 1.0231 | Aggregation-prone |
| 184 | Q | B | 0.2175 | Aggregation-prone |
| 185 | S | B | -0.0781 | Soluble |
| 186 | S | B | -0.2173 | Soluble |
| 187 | G | B | -0.0427 | Soluble |
| 188 | L | B | -0.0909 | Soluble |
| 189 | Y | B | 0.2419 | Aggregation-prone |
| 190 | S | B | 0.0000 | Buried |
| 191 | L | B | 0.0000 | Buried |
| 192 | S | B | 0.0000 | Buried |
| 193 | S | B | 0.0000 | Buried |
| 194 | V | B | 0.0000 | Buried |
| 195 | V | B | 0.0000 | Buried |
| 196 | T | B | -0.1519 | Soluble |
| 197 | V | B | 0.0000 | Buried |
| 198 | P | B | -0.6099 | Soluble |
| 199 | S | B | -0.8960 | Soluble |
| 200 | S | B | -0.9226 | Soluble |
| 201 | S | B | -0.6787 | Soluble |
| 202 | L | B | -1.2087 | Soluble |
| 203 | G | B | -1.2044 | Soluble |
| 204 | T | B | -0.8469 | Soluble |
| 205 | K | B | -1.3274 | Soluble |
| 206 | T | B | -1.3471 | Soluble |
| 207 | Y | B | 0.0000 | Buried |
| 208 | T | B | -1.7111 | Soluble |
| 209 | C | B | 0.0000 | Buried |
| 210 | N | B | -1.7094 | Soluble |
| 211 | V | B | 0.0000 | Buried |
| 212 | D | B | -2.3701 | Soluble |
| 213 | H | B | 0.0000 | Buried |
| 214 | K | B | -2.9503 | Soluble |
| 215 | P | B | -1.8539 | Soluble |
| 216 | S | B | -1.9955 | Soluble |
| 217 | N | B | -2.7440 | Soluble |
| 218 | T | B | -2.2145 | Soluble |
| 219 | K | B | -2.8173 | Soluble |
| 220 | V | B | -1.6122 | Soluble |
| 221 | D | B | -2.7780 | Soluble |
| 222 | K | B | -2.2912 | Soluble |
| 223 | R | B | -2.9108 | Soluble |
| 224 | V | B | 0.0000 | Buried |
| 225 | E | B | -2.8789 | Soluble |
| 226 | S | B | -1.8315 | Soluble |
| 227 | K | B | -2.0898 | Soluble |
| 228 | Y | B | -0.3406 | Soluble |
| 1 | D | A | -1.9045 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.0253 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.4730 | Soluble |
| 6 | Q | A | -1.0660 | Soluble |
| 7 | S | A | -0.7659 | Soluble |
| 8 | P | A | -0.5922 | Soluble |
| 9 | S | A | -0.7471 | Soluble |
| 10 | S | A | -0.7443 | Soluble |
| 11 | L | A | -0.5016 | Soluble |
| 12 | S | A | -0.8298 | Soluble |
| 13 | A | A | 0.0000 | Buried |
| 14 | S | A | -0.4585 | Soluble |
| 15 | V | A | 0.5127 | Aggregation-prone |
| 16 | G | A | -0.6332 | Soluble |
| 17 | D | A | -1.5586 | Soluble |
| 18 | R | A | -2.2570 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6394 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -1.0253 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.9767 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.9155 | Soluble |
| 27 | Q | A | -2.1025 | Soluble |
| 28 | G | A | -1.6527 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | S | A | -1.0145 | Soluble |
| 37 | S | A | -0.6489 | Soluble |
| 38 | S | A | -0.5702 | Soluble |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.7297 | Soluble |
| 46 | P | A | -1.5323 | Soluble |
| 47 | G | A | -1.6570 | Soluble |
| 48 | K | A | -2.6150 | Soluble |
| 49 | A | A | 0.0000 | Buried |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.8934 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.0000 | Buried |
| 56 | G | A | -0.8833 | Soluble |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -1.2599 | Soluble |
| 66 | E | A | -1.8609 | Soluble |
| 67 | T | A | -1.1706 | Soluble |
| 68 | E | A | -1.0712 | Soluble |
| 69 | S | A | -0.7184 | Soluble |
| 70 | G | A | -0.5602 | Soluble |
| 71 | V | A | -0.4508 | Soluble |
| 72 | P | A | -0.3847 | Soluble |
| 74 | S | A | -0.5226 | Soluble |
| 75 | R | A | -0.7627 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.6894 | Soluble |
| 78 | G | A | -0.7325 | Soluble |
| 79 | S | A | -0.9954 | Soluble |
| 80 | G | A | -1.1023 | Soluble |
| 83 | S | A | -1.1199 | Soluble |
| 84 | G | A | -1.5129 | Soluble |
| 85 | T | A | -2.1408 | Soluble |
| 86 | D | A | -2.8793 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.9013 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6280 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.3413 | Soluble |
| 93 | S | A | -1.0088 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -0.7988 | Soluble |
| 96 | P | A | -0.7879 | Soluble |
| 97 | E | A | -1.8520 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.4680 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -0.7084 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | N | A | 0.0000 | Buried |
| 107 | T | A | 0.0000 | Buried |
| 108 | K | A | -0.6327 | Soluble |
| 109 | V | A | -0.0567 | Soluble |
| 110 | G | A | -0.2749 | Soluble |
| 112 | S | A | -0.7402 | Soluble |
| 113 | S | A | -0.6984 | Soluble |
| 114 | Y | A | -0.8821 | Soluble |
| 115 | G | A | 0.0000 | Buried |
| 116 | N | A | 0.0000 | Buried |
| 117 | T | A | -0.7445 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | G | A | -1.2293 | Soluble |
| 121 | G | A | -0.9288 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.1321 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | -0.9813 | Soluble |
| 126 | I | A | -0.4219 | Soluble |
| 127 | K | A | -1.3447 | Soluble |
| 128 | R | A | -0.9508 | Soluble |
| 129 | T | A | 0.1626 | Aggregation-prone |
| 130 | V | A | 1.1624 | Aggregation-prone |
| 131 | A | A | 0.4923 | Aggregation-prone |
| 132 | A | A | 0.0726 | Aggregation-prone |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.0947 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0230 | Aggregation-prone |
| 137 | I | A | -0.0241 | Soluble |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.3545 | Soluble |
| 140 | P | A | -0.6094 | Soluble |
| 141 | S | A | -1.6108 | Soluble |
| 142 | D | A | -2.8681 | Soluble |
| 143 | E | A | -2.5681 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1676 | Soluble |
| 146 | K | A | -2.6669 | Soluble |
| 147 | S | A | -1.6259 | Soluble |
| 148 | G | A | -1.3083 | Soluble |
| 149 | T | A | -0.9603 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8156 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.6503 | Soluble |
| 162 | R | A | -3.2275 | Soluble |
| 163 | E | A | -3.2850 | Soluble |
| 164 | A | A | -2.3722 | Soluble |
| 165 | K | A | -2.4310 | Soluble |
| 166 | V | A | -1.0711 | Soluble |
| 167 | Q | A | -0.5661 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.4833 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.4222 | Soluble |
| 172 | N | A | -1.2965 | Soluble |
| 173 | A | A | -0.1065 | Soluble |
| 174 | L | A | 0.8291 | Aggregation-prone |
| 175 | Q | A | -0.3461 | Soluble |
| 176 | S | A | -0.6687 | Soluble |
| 177 | G | A | -1.2843 | Soluble |
| 178 | N | A | -1.6132 | Soluble |
| 179 | S | A | -1.4897 | Soluble |
| 180 | Q | A | -1.5224 | Soluble |
| 181 | E | A | -1.9078 | Soluble |
| 182 | S | A | -0.7754 | Soluble |
| 183 | V | A | -0.6824 | Soluble |
| 184 | T | A | -1.0624 | Soluble |
| 185 | E | A | -2.2650 | Soluble |
| 186 | Q | A | -1.8228 | Soluble |
| 187 | D | A | -1.8239 | Soluble |
| 188 | S | A | -1.6786 | Soluble |
| 189 | K | A | -2.1868 | Soluble |
| 190 | D | A | -1.5395 | Soluble |
| 191 | S | A | -1.6278 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.7423 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.5296 | Soluble |
| 201 | L | A | -0.8295 | Soluble |
| 202 | S | A | -1.0940 | Soluble |
| 203 | K | A | -2.1248 | Soluble |
| 204 | A | A | -1.9621 | Soluble |
| 205 | D | A | -2.7099 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.6311 | Soluble |
| 208 | K | A | -3.6218 | Soluble |
| 209 | H | A | -2.8688 | Soluble |
| 210 | K | A | -3.2439 | Soluble |
| 211 | V | A | -1.3597 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.8537 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1184 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6452 | Soluble |
| 220 | G | A | -0.2635 | Soluble |
| 221 | L | A | -0.1469 | Soluble |
| 222 | S | A | -0.4364 | Soluble |
| 223 | S | A | -0.3960 | Soluble |
| 224 | P | A | -0.5911 | Soluble |
| 225 | V | A | -0.0629 | Soluble |
| 226 | T | A | -0.5170 | Soluble |
| 227 | K | A | -0.8139 | Soluble |
| 228 | S | A | -0.7158 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -2.2000 | Soluble |
| 231 | R | A | -2.6846 | Soluble |
| 232 | G | A | -2.2857 | Soluble |
| 233 | E | A | -2.4655 | Soluble |
| 234 | C | A | -1.2675 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7465 | 2.3576 | CSV PDB |
| 4.5 | -0.7895 | 2.2792 | CSV PDB |
| 5.0 | -0.8415 | 2.1955 | CSV PDB |
| 5.5 | -0.8917 | 2.11 | CSV PDB |
| 6.0 | -0.9283 | 2.024 | CSV PDB |
| 6.5 | -0.9418 | 1.938 | CSV PDB |
| 7.0 | -0.9312 | 1.9094 | CSV PDB |
| 7.5 | -0.9042 | 1.9094 | CSV PDB |
| 8.0 | -0.8684 | 1.9094 | CSV PDB |
| 8.5 | -0.8266 | 1.9094 | CSV PDB |
| 9.0 | -0.7788 | 1.9094 | CSV PDB |