Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMDWVRQAPGKGLEWVSAITMSGITAYYTDDVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKEEFLPGTHYFYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKAIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKLLIYSASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCLQDYNYPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | F (Heavy), E (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | F | -2.0475 | Soluble |
| 2 | V | F | -1.1362 | Soluble |
| 3 | Q | F | -1.2439 | Soluble |
| 4 | L | F | 0.0000 | Buried |
| 5 | V | F | 0.9710 | Aggregation-prone |
| 6 | E | F | 0.0000 | Buried |
| 7 | S | F | -0.4831 | Soluble |
| 8 | G | F | -1.1448 | Soluble |
| 9 | G | F | -0.6701 | Soluble |
| 11 | G | F | -0.2591 | Soluble |
| 12 | L | F | 0.2397 | Aggregation-prone |
| 13 | V | F | -0.3582 | Soluble |
| 14 | Q | F | -1.4330 | Soluble |
| 15 | P | F | -1.6407 | Soluble |
| 16 | G | F | -1.4164 | Soluble |
| 17 | G | F | -1.1348 | Soluble |
| 18 | S | F | -1.4231 | Soluble |
| 19 | L | F | -1.3137 | Soluble |
| 20 | R | F | -2.3830 | Soluble |
| 21 | L | F | 0.0000 | Buried |
| 22 | S | F | -0.4737 | Soluble |
| 23 | C | F | 0.0000 | Buried |
| 24 | A | F | -0.0963 | Soluble |
| 25 | A | F | 0.0000 | Buried |
| 26 | S | F | -0.8099 | Soluble |
| 27 | G | F | -1.1336 | Soluble |
| 28 | F | F | -0.4522 | Soluble |
| 29 | T | F | -0.1776 | Soluble |
| 30 | F | F | 0.0000 | Buried |
| 35 | S | F | -0.6494 | Soluble |
| 36 | S | F | -0.2461 | Soluble |
| 37 | Y | F | 0.0801 | Aggregation-prone |
| 38 | A | F | -0.0028 | Soluble |
| 39 | M | F | 0.0000 | Buried |
| 40 | D | F | 0.0000 | Buried |
| 41 | W | F | 0.0000 | Buried |
| 42 | V | F | 0.0000 | Buried |
| 43 | R | F | 0.0000 | Buried |
| 44 | Q | F | -0.8135 | Soluble |
| 45 | A | F | -1.1995 | Soluble |
| 46 | P | F | -0.9729 | Soluble |
| 47 | G | F | -1.5121 | Soluble |
| 48 | K | F | -2.3904 | Soluble |
| 49 | G | F | -1.6599 | Soluble |
| 50 | L | F | 0.0000 | Buried |
| 51 | E | F | -1.2453 | Soluble |
| 52 | W | F | 0.0000 | Buried |
| 53 | V | F | 0.0000 | Buried |
| 54 | S | F | 0.0000 | Buried |
| 55 | A | F | 0.0000 | Buried |
| 56 | I | F | 0.0000 | Buried |
| 57 | T | F | 0.3475 | Aggregation-prone |
| 58 | M | F | 0.1272 | Aggregation-prone |
| 59 | S | F | 0.2372 | Aggregation-prone |
| 62 | G | F | 0.4842 | Aggregation-prone |
| 63 | I | F | 1.8346 | Aggregation-prone |
| 64 | T | F | 0.9643 | Aggregation-prone |
| 65 | A | F | 0.6556 | Aggregation-prone |
| 66 | Y | F | 0.1660 | Aggregation-prone |
| 67 | Y | F | -0.6336 | Soluble |
| 68 | T | F | 0.0000 | Buried |
| 69 | D | F | -2.5275 | Soluble |
| 70 | D | F | -2.1782 | Soluble |
| 71 | V | F | 0.0000 | Buried |
| 72 | K | F | -2.6069 | Soluble |
| 74 | G | F | -1.8735 | Soluble |
| 75 | R | F | -1.6355 | Soluble |
| 76 | F | F | 0.0000 | Buried |
| 77 | T | F | -0.9741 | Soluble |
| 78 | I | F | 0.0000 | Buried |
| 79 | S | F | -0.1408 | Soluble |
| 80 | R | F | -0.7094 | Soluble |
| 81 | D | F | -1.5493 | Soluble |
| 82 | N | F | -1.6421 | Soluble |
| 83 | S | F | -1.5576 | Soluble |
| 84 | K | F | -2.3583 | Soluble |
| 85 | N | F | -1.7150 | Soluble |
| 86 | T | F | -0.9927 | Soluble |
| 87 | L | F | 0.0000 | Buried |
| 88 | Y | F | -0.6553 | Soluble |
| 89 | L | F | 0.0000 | Buried |
| 90 | Q | F | -1.6457 | Soluble |
| 91 | M | F | 0.0000 | Buried |
| 92 | N | F | -2.1586 | Soluble |
| 93 | S | F | -1.5090 | Soluble |
| 94 | L | F | 0.0000 | Buried |
| 95 | R | F | -2.0006 | Soluble |
| 96 | A | F | -1.5210 | Soluble |
| 97 | E | F | -2.1464 | Soluble |
| 98 | D | F | 0.0000 | Buried |
| 99 | T | F | -0.6605 | Soluble |
| 100 | A | F | 0.0000 | Buried |
| 101 | V | F | 0.2166 | Aggregation-prone |
| 102 | Y | F | 0.0000 | Buried |
| 103 | Y | F | 0.0000 | Buried |
| 104 | C | F | 0.0000 | Buried |
| 105 | A | F | 0.0000 | Buried |
| 106 | K | F | 0.0000 | Buried |
| 107 | E | F | 0.0000 | Buried |
| 108 | E | F | -0.0043 | Soluble |
| 109 | F | F | 0.2957 | Aggregation-prone |
| 110 | L | F | 0.4174 | Aggregation-prone |
| 111 | P | F | -0.2901 | Soluble |
| 111A | G | F | -0.5563 | Soluble |
| 111B | T | F | -0.3405 | Soluble |
| 112B | H | F | -0.5015 | Soluble |
| 112A | Y | F | 0.5169 | Aggregation-prone |
| 112 | F | F | 0.8802 | Aggregation-prone |
| 113 | Y | F | 0.4947 | Aggregation-prone |
| 114 | G | F | 0.0000 | Buried |
| 115 | M | F | 0.0000 | Buried |
| 116 | D | F | -0.7852 | Soluble |
| 117 | V | F | -0.4602 | Soluble |
| 118 | W | F | 0.0000 | Buried |
| 119 | G | F | 0.0000 | Buried |
| 120 | Q | F | -1.3297 | Soluble |
| 121 | G | F | 0.0000 | Buried |
| 122 | T | F | -0.1483 | Soluble |
| 123 | T | F | -0.0978 | Soluble |
| 124 | V | F | 0.0000 | Buried |
| 125 | T | F | -0.4357 | Soluble |
| 126 | V | F | 0.0000 | Buried |
| 127 | S | F | -0.8625 | Soluble |
| 128 | S | F | -0.6973 | Soluble |
| 129 | A | F | -0.4843 | Soluble |
| 130 | S | F | -0.5950 | Soluble |
| 131 | T | F | -0.8407 | Soluble |
| 132 | K | F | -1.3555 | Soluble |
| 133 | G | F | -1.4961 | Soluble |
| 134 | P | F | -0.7356 | Soluble |
| 135 | S | F | -0.2977 | Soluble |
| 136 | V | F | 0.0000 | Buried |
| 137 | F | F | 0.0000 | Buried |
| 138 | P | F | -1.1786 | Soluble |
| 139 | L | F | 0.0000 | Buried |
| 140 | A | F | -1.1390 | Soluble |
| 141 | P | F | 0.0000 | Buried |
| 142 | S | F | -0.8934 | Soluble |
| 143 | S | F | -1.4746 | Soluble |
| 144 | K | F | -1.9876 | Soluble |
| 145 | S | F | -1.3966 | Soluble |
| 146 | G | F | -0.8160 | Soluble |
| 147 | G | F | -0.9905 | Soluble |
| 148 | T | F | -0.7445 | Soluble |
| 149 | A | F | 0.0000 | Buried |
| 150 | A | F | 0.0000 | Buried |
| 151 | L | F | 0.0000 | Buried |
| 152 | G | F | 0.0000 | Buried |
| 153 | C | F | 0.0000 | Buried |
| 154 | L | F | 0.0000 | Buried |
| 155 | V | F | 0.0000 | Buried |
| 156 | K | F | 0.0000 | Buried |
| 157 | D | F | -0.4873 | Soluble |
| 158 | Y | F | 0.0000 | Buried |
| 159 | F | F | 0.0000 | Buried |
| 160 | P | F | 0.0000 | Buried |
| 161 | E | F | -1.1142 | Soluble |
| 162 | P | F | -1.2079 | Soluble |
| 163 | V | F | -1.0554 | Soluble |
| 164 | T | F | -0.8613 | Soluble |
| 165 | V | F | -0.4862 | Soluble |
| 166 | S | F | -0.4507 | Soluble |
| 167 | W | F | 0.0000 | Buried |
| 168 | N | F | -0.6645 | Soluble |
| 169 | S | F | -0.5914 | Soluble |
| 170 | G | F | -0.5783 | Soluble |
| 171 | A | F | -0.2439 | Soluble |
| 172 | L | F | -0.0191 | Soluble |
| 173 | T | F | -0.1922 | Soluble |
| 174 | S | F | -0.1961 | Soluble |
| 175 | G | F | -0.2337 | Soluble |
| 176 | V | F | 0.1221 | Aggregation-prone |
| 177 | H | F | -0.2750 | Soluble |
| 178 | T | F | 0.0447 | Aggregation-prone |
| 179 | F | F | 0.0000 | Buried |
| 180 | P | F | -0.3179 | Soluble |
| 181 | A | F | 0.0376 | Aggregation-prone |
| 182 | V | F | 0.4309 | Aggregation-prone |
| 183 | L | F | 1.0780 | Aggregation-prone |
| 184 | Q | F | 0.2421 | Aggregation-prone |
| 185 | S | F | -0.0446 | Soluble |
| 186 | S | F | -0.2002 | Soluble |
| 187 | G | F | 0.0121 | Aggregation-prone |
| 188 | L | F | -0.0459 | Soluble |
| 189 | Y | F | 0.0000 | Buried |
| 190 | S | F | 0.0000 | Buried |
| 191 | L | F | 0.0000 | Buried |
| 192 | S | F | 0.0000 | Buried |
| 193 | S | F | 0.0000 | Buried |
| 194 | V | F | 0.0000 | Buried |
| 195 | V | F | 0.0000 | Buried |
| 196 | T | F | -0.1519 | Soluble |
| 197 | V | F | 0.0000 | Buried |
| 198 | P | F | -0.5355 | Soluble |
| 199 | S | F | -0.7913 | Soluble |
| 200 | S | F | -0.6944 | Soluble |
| 201 | S | F | -0.6325 | Soluble |
| 202 | L | F | -0.7562 | Soluble |
| 203 | G | F | -0.9619 | Soluble |
| 204 | T | F | -0.7096 | Soluble |
| 205 | Q | F | -1.1852 | Soluble |
| 206 | T | F | -1.1148 | Soluble |
| 207 | Y | F | 0.0000 | Buried |
| 208 | I | F | -1.0943 | Soluble |
| 209 | C | F | 0.0000 | Buried |
| 210 | N | F | -1.4363 | Soluble |
| 211 | V | F | 0.0000 | Buried |
| 212 | N | F | -2.4811 | Soluble |
| 213 | H | F | 0.0000 | Buried |
| 214 | K | F | -2.9523 | Soluble |
| 215 | P | F | -1.7770 | Soluble |
| 216 | S | F | -1.9449 | Soluble |
| 217 | N | F | -2.6674 | Soluble |
| 218 | T | F | -2.2255 | Soluble |
| 219 | K | F | -2.7754 | Soluble |
| 220 | V | F | -1.3434 | Soluble |
| 221 | D | F | -1.9882 | Soluble |
| 222 | K | F | -1.7621 | Soluble |
| 223 | K | F | -2.4798 | Soluble |
| 224 | V | F | 0.0000 | Buried |
| 225 | E | F | -2.8313 | Soluble |
| 226 | P | F | -2.0734 | Soluble |
| 227 | K | F | -2.0756 | Soluble |
| 1 | A | E | -0.7101 | Soluble |
| 2 | I | E | 0.0000 | Buried |
| 3 | Q | E | -1.8174 | Soluble |
| 4 | M | E | 0.0000 | Buried |
| 5 | T | E | -1.3471 | Soluble |
| 6 | Q | E | 0.0000 | Buried |
| 7 | S | E | -0.7878 | Soluble |
| 8 | P | E | -0.4581 | Soluble |
| 9 | S | E | -0.8097 | Soluble |
| 10 | S | E | -0.6486 | Soluble |
| 11 | L | E | -0.4124 | Soluble |
| 12 | S | E | -0.7879 | Soluble |
| 13 | A | E | 0.0000 | Buried |
| 14 | S | E | -0.5625 | Soluble |
| 15 | V | E | 0.2092 | Aggregation-prone |
| 16 | G | E | -0.7742 | Soluble |
| 17 | D | E | -1.6809 | Soluble |
| 18 | R | E | -2.2988 | Soluble |
| 19 | V | E | 0.0000 | Buried |
| 20 | T | E | -0.5975 | Soluble |
| 21 | I | E | 0.0000 | Buried |
| 22 | T | E | -0.7452 | Soluble |
| 23 | C | E | 0.0000 | Buried |
| 24 | R | E | -2.4710 | Soluble |
| 25 | A | E | -1.9763 | Soluble |
| 26 | S | E | -1.7434 | Soluble |
| 27 | Q | E | -2.3389 | Soluble |
| 28 | G | E | -2.0595 | Soluble |
| 29 | I | E | 0.0000 | Buried |
| 36 | R | E | -2.6181 | Soluble |
| 37 | N | E | -1.8969 | Soluble |
| 38 | D | E | 0.0000 | Buried |
| 39 | L | E | 0.0000 | Buried |
| 40 | G | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | Y | E | 0.0000 | Buried |
| 43 | Q | E | 0.0000 | Buried |
| 44 | Q | E | 0.0000 | Buried |
| 45 | K | E | -1.7883 | Soluble |
| 46 | P | E | -1.5853 | Soluble |
| 47 | G | E | -1.6999 | Soluble |
| 48 | K | E | -2.6214 | Soluble |
| 49 | A | E | -1.7620 | Soluble |
| 50 | P | E | 0.0000 | Buried |
| 51 | K | E | -1.9534 | Soluble |
| 52 | L | E | 0.0000 | Buried |
| 53 | L | E | 0.0000 | Buried |
| 54 | I | E | 0.0000 | Buried |
| 55 | Y | E | 0.0518 | Aggregation-prone |
| 56 | S | E | -0.4078 | Soluble |
| 57 | A | E | 0.0000 | Buried |
| 65 | S | E | -0.3904 | Soluble |
| 66 | T | E | 0.0250 | Aggregation-prone |
| 67 | L | E | 0.2036 | Aggregation-prone |
| 68 | Q | E | -0.3903 | Soluble |
| 69 | S | E | -0.3814 | Soluble |
| 70 | G | E | -0.5048 | Soluble |
| 71 | V | E | -0.3727 | Soluble |
| 72 | P | E | -0.3454 | Soluble |
| 74 | S | E | -0.4328 | Soluble |
| 75 | R | E | -0.7889 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | S | E | -0.2995 | Soluble |
| 78 | G | E | -0.2435 | Soluble |
| 79 | S | E | -0.6732 | Soluble |
| 80 | G | E | -1.3845 | Soluble |
| 83 | S | E | -1.6610 | Soluble |
| 84 | G | E | -2.1238 | Soluble |
| 85 | T | E | -2.1864 | Soluble |
| 86 | D | E | -2.4005 | Soluble |
| 87 | F | E | 0.0000 | Buried |
| 88 | T | E | -0.6680 | Soluble |
| 89 | L | E | 0.0000 | Buried |
| 90 | T | E | -0.5762 | Soluble |
| 91 | I | E | 0.0000 | Buried |
| 92 | S | E | -1.3139 | Soluble |
| 93 | S | E | -1.1225 | Soluble |
| 94 | L | E | 0.0000 | Buried |
| 95 | Q | E | -0.8116 | Soluble |
| 96 | P | E | -0.8587 | Soluble |
| 97 | E | E | -1.8750 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | F | E | -0.4610 | Soluble |
| 100 | A | E | -0.7449 | Soluble |
| 101 | T | E | -0.8628 | Soluble |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | L | E | 0.0000 | Buried |
| 106 | Q | E | 0.0000 | Buried |
| 107 | D | E | 0.0000 | Buried |
| 108 | Y | E | -0.0231 | Soluble |
| 109 | N | E | -0.3922 | Soluble |
| 114 | Y | E | 0.0715 | Aggregation-prone |
| 115 | P | E | -0.2303 | Soluble |
| 116 | W | E | 0.0000 | Buried |
| 117 | T | E | -0.5706 | Soluble |
| 118 | F | E | 0.0000 | Buried |
| 119 | G | E | 0.0000 | Buried |
| 120 | Q | E | -1.7437 | Soluble |
| 121 | G | E | 0.0000 | Buried |
| 122 | T | E | 0.0000 | Buried |
| 123 | K | E | -1.3065 | Soluble |
| 124 | V | E | 0.0000 | Buried |
| 125 | E | E | 0.0000 | Buried |
| 126 | I | E | -0.4671 | Soluble |
| 127 | K | E | -1.4031 | Soluble |
| 128 | R | E | -1.0414 | Soluble |
| 129 | T | E | -0.1117 | Soluble |
| 130 | V | E | 0.5343 | Aggregation-prone |
| 131 | A | E | 0.1683 | Aggregation-prone |
| 132 | A | E | -0.1263 | Soluble |
| 133 | P | E | 0.0000 | Buried |
| 134 | S | E | -0.1852 | Soluble |
| 135 | V | E | 0.0000 | Buried |
| 136 | F | E | -0.0232 | Soluble |
| 137 | I | E | 0.0217 | Aggregation-prone |
| 138 | F | E | 0.0000 | Buried |
| 139 | P | E | -0.5259 | Soluble |
| 140 | P | E | 0.0000 | Buried |
| 141 | S | E | -1.7983 | Soluble |
| 142 | D | E | -2.9150 | Soluble |
| 143 | E | E | -2.9730 | Soluble |
| 144 | Q | E | 0.0000 | Buried |
| 145 | L | E | -2.1997 | Soluble |
| 146 | K | E | -2.7764 | Soluble |
| 147 | S | E | -1.7315 | Soluble |
| 148 | G | E | -1.2444 | Soluble |
| 149 | T | E | -0.8256 | Soluble |
| 150 | A | E | 0.0000 | Buried |
| 151 | S | E | 0.0000 | Buried |
| 152 | V | E | 0.0000 | Buried |
| 153 | V | E | 0.0000 | Buried |
| 154 | C | E | 0.0000 | Buried |
| 155 | L | E | 0.0000 | Buried |
| 156 | L | E | 0.0000 | Buried |
| 157 | N | E | -0.3681 | Soluble |
| 158 | N | E | -0.7175 | Soluble |
| 159 | F | E | 0.0000 | Buried |
| 160 | Y | E | 0.0000 | Buried |
| 161 | P | E | -1.2928 | Soluble |
| 162 | R | E | -1.8546 | Soluble |
| 163 | E | E | -2.7142 | Soluble |
| 164 | A | E | -2.0473 | Soluble |
| 165 | K | E | -2.2083 | Soluble |
| 166 | V | E | -1.0272 | Soluble |
| 167 | Q | E | -0.4631 | Soluble |
| 168 | W | E | 0.0000 | Buried |
| 169 | K | E | -0.4411 | Soluble |
| 170 | V | E | 0.0000 | Buried |
| 171 | D | E | -1.7387 | Soluble |
| 172 | N | E | -1.3169 | Soluble |
| 173 | A | E | -0.2420 | Soluble |
| 174 | L | E | 0.7477 | Aggregation-prone |
| 175 | Q | E | -0.1479 | Soluble |
| 176 | S | E | -0.3686 | Soluble |
| 177 | G | E | -0.9189 | Soluble |
| 178 | N | E | -0.8314 | Soluble |
| 179 | S | E | -1.1995 | Soluble |
| 180 | Q | E | -1.5639 | Soluble |
| 181 | E | E | -1.9371 | Soluble |
| 182 | S | E | -0.6504 | Soluble |
| 183 | V | E | -0.2042 | Soluble |
| 184 | T | E | -0.8251 | Soluble |
| 185 | E | E | -2.0045 | Soluble |
| 186 | Q | E | -1.5522 | Soluble |
| 187 | D | E | -1.8060 | Soluble |
| 188 | S | E | -1.6019 | Soluble |
| 189 | K | E | -2.1852 | Soluble |
| 190 | D | E | -1.5496 | Soluble |
| 191 | S | E | -1.5917 | Soluble |
| 192 | T | E | 0.0000 | Buried |
| 193 | Y | E | 0.0000 | Buried |
| 194 | S | E | 0.0000 | Buried |
| 195 | L | E | 0.0000 | Buried |
| 196 | S | E | 0.0000 | Buried |
| 197 | S | E | 0.0000 | Buried |
| 198 | T | E | -0.6880 | Soluble |
| 199 | L | E | 0.0000 | Buried |
| 200 | T | E | -0.4299 | Soluble |
| 201 | L | E | -0.5853 | Soluble |
| 202 | S | E | -1.1387 | Soluble |
| 203 | K | E | -1.9482 | Soluble |
| 204 | A | E | -1.7242 | Soluble |
| 205 | D | E | -2.3679 | Soluble |
| 206 | Y | E | 0.0000 | Buried |
| 207 | E | E | -3.1041 | Soluble |
| 208 | K | E | -3.3416 | Soluble |
| 209 | H | E | -2.8343 | Soluble |
| 210 | K | E | -2.9199 | Soluble |
| 211 | V | E | -1.2954 | Soluble |
| 212 | Y | E | 0.0000 | Buried |
| 213 | A | E | 0.0000 | Buried |
| 214 | C | E | 0.0000 | Buried |
| 215 | E | E | -0.6939 | Soluble |
| 216 | V | E | 0.0000 | Buried |
| 217 | T | E | -1.1749 | Soluble |
| 218 | H | E | 0.0000 | Buried |
| 219 | Q | E | -1.6705 | Soluble |
| 220 | G | E | -0.4884 | Soluble |
| 221 | L | E | -0.2993 | Soluble |
| 222 | S | E | -0.4940 | Soluble |
| 223 | S | E | -0.4230 | Soluble |
| 224 | P | E | -0.4979 | Soluble |
| 225 | V | E | -0.0027 | Soluble |
| 226 | T | E | -0.5107 | Soluble |
| 227 | K | E | -0.8911 | Soluble |
| 228 | S | E | -0.6371 | Soluble |
| 229 | F | E | -0.9199 | Soluble |
| 230 | N | E | -1.8448 | Soluble |
| 231 | R | E | -2.4166 | Soluble |
| 232 | G | E | -1.9900 | Soluble |
| 233 | E | E | -2.1955 | Soluble |
| 234 | C | E | -0.8451 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7226 | 2.5581 | CSV PDB |
| 4.5 | -0.7604 | 2.5581 | CSV PDB |
| 5.0 | -0.8039 | 2.5581 | CSV PDB |
| 5.5 | -0.8435 | 2.5581 | CSV PDB |
| 6.0 | -0.8677 | 2.5581 | CSV PDB |
| 6.5 | -0.8673 | 2.5581 | CSV PDB |
| 7.0 | -0.8432 | 2.5581 | CSV PDB |
| 7.5 | -0.8045 | 2.5581 | CSV PDB |
| 8.0 | -0.7585 | 2.5581 | CSV PDB |
| 8.5 | -0.7073 | 2.5581 | CSV PDB |
| 9.0 | -0.651 | 2.5581 | CSV PDB |