Gremubamab

A4DAB136 | Phase-II
PcrV type III secretion system;Polysaccharide synthesis locus (Pseudomonas)
G1;G1 / None
MedImmune
Phase-II
Bispecific mAb
MEDI-3902 MEDI3902 MEDI 3902
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IMGT PubChem (377483940) PubChem (404719677) PubChem (404772458) PubChem (472421156) PubChem (476264156) PubChem (476270766) PubChem (496703344) PubChem (505778447) Thera-SAbDab YAbS
Avg A4D Score
-0.6689
Score Range
-0.68 to -0.66
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB136_6cyf_M_L 6cyf 98% -0.662 6.5 9.0 -0.1656 -0.7277
A4DAB136_6cyf_D_C 6cyf 98% -0.6604 6.5 9.0 -0.1462 -0.7282
A4DAB136_6cyf_U_T 6cyf 98% -0.6767 6.5 9.0 -0.1687 -0.7439
A4DAB136_6cyf_F_E 6cyf 98% -0.6765 6.0 9.0 -0.1788 -0.7422