We develop and design computational tools for structural biology that include easy-to-use web servers and comprehensive standalone applications for advanced users.
CABS-dock for protein-peptide docking, CABS-flex 2.0 for fast simulations of protein flexibility, Aggrescan3D for structure-based prediction of protein aggregation properties
CABS-flex simulation environment for fast modeling of protein flexibility, CABS-dock toolbox for modeling protein-peptide interactions, Aggrescan3D for structure-based design of soluble protein variants
We provide computational biology services to academics and private partners. The services include broad range of computational support to biomedical research: modeling of proteins or their complexes (in particular protein-peptide complexes), structure prediction and dynamic simulations of biological systems, structure-based drug design, bioinformatics, biostatistics and big data analysis.
To provide computational services, we employ cyberinfrastructure of the University of Warsaw Biological and Chemical Research Centre (high performance computing cluster). The high capacity of our cluster (382 teraflops) open exciting possibilities for simulations of complex biological systems, big data analysis and other large-scale computations.
We are constantly looking for motivated individuals to join our team or to remotely cooperate on defined goals. We offer trainings, support in pursuing scientific projects in different areas of computational biology, or a cozy desk in our facilities in Warsaw. The possibility of financial support depends on ongoing grants.
The 26S proteasome is a multi-catalytic ATP-dependent protease complex that recognizes and cleaves damaged or misfo(...) Read more
Protein aggregation is a major hurdle in the development and manufacturing of protein-based therapeutics. The devel(...) Read more
Most of the protein–protein docking methods treat proteins as almost rigid objects. Only the side-chains flexibilit(...) Read more