Ansuvimab

A4DAB020 | Infectious diseases | Approved
Zaire Ebolavirus Glycoprotein
G1 / IgG1
Ridgeback Biotherapeutics
Approved
Whole mAb
EVB114 EVB-114
6
IMGT PubChem (433770931) PubChem (440234910) PubChem (472421480) PubChem (483928999) PubChem (505057014) PubChem (513906939) Thera-SAbDab YAbS
Avg A4D Score
-0.7004
Score Range
-0.72 to -0.69
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB020_5fhc_H_L 5fhc 99% -0.7154 6.5 9.0 -0.6296 -0.7258
A4DAB020_5fha_H_L 5fha 99% -0.6853 6.5 4.0 -0.7115 -0.6821