Anzurstobart

A4DAB022 | Phase-I
SIRPA
G1 / None
Celgene Corporation
Phase-I
Whole mAb
BMS-986351 BMS986351 CC-95251 CC95251
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IMGT PubChem (462764898) PubChem (472420553) PubChem (476000790) PubChem (485483278) PubChem (485511860) Thera-SAbDab YAbS
Avg A4D Score
-0.6766
Score Range
-0.69 to -0.67
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB022_7st5_h_l 7st5 100% -0.6667 6.5 9.0 -0.3116 -0.7118
A4DAB022_7st5_H_L 7st5 100% -0.6865 6.5 9.0 -0.2983 -0.7358