Apitegromab

A4DAB023 | Muscular disorders | Preregistration
pro-MSTN/GDF8/GDF-8/pro-GDF8
G4 / IgG4
Scholar Rock
Preregistration
Whole mAb
SRK-015 SRK015
—
IMGT PubChem (404914099) PubChem (434122240) PubChem (440234904) PubChem (472422584) PubChem (476262770) PubChem (476269431) Thera-SAbDab YAbS
Avg A4D Score
-0.6681
Score Range
-0.67 to -0.67
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB023_6umx_h_l 6umx 95% -0.6673 6.5 4.0 -0.0871 -0.753
A4DAB023_6umx_H_L 6umx 95% -0.6688 6.5 4.0 -0.1479 -0.7448