Atisnolerbart

A4DAB027 | Phase-III

Target Bet v 1

Isotype / Subclass G4 / None

Company

Regeneron

Clinical Status Phase-III

Format Whole mAb

Synonyms

REGN5713-5714-5715 (combination of Atisnolerbart Bremzalerbart and Umesolerbart)

pH Formulation —

IMGT PubChem (471299097) PubChem (474492731) PubChem (485483316) PubChem (485511889) PubChem (494431122) Thera-SAbDab YAbS

Avg A4D Score

-0.6742

Score Range

-0.69 to -0.66

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB027_7mxl_J_K	7mxl	100%	-0.6891	6.5	4.0	-0.3307	-0.7345
A4DAB027_7n0v_H_L	7n0v	100%	-0.6593	6.5	4.0	-0.2998	-0.7051