Bremzalerbart

A4DAB054 | Phase-III

Target Bet v 1

Isotype / Subclass G4 / None

Company

Regeneron Pharmaceutical

Clinical Status Phase-III

Format Whole mAb

Synonyms

REGN5713-5714-5715 (combination of Atisnolerbart Bremzalerbart and Umesolerbart)

pH Formulation —

IMGT PubChem (471298997) PubChem (474492837) PubChem (485483315) PubChem (485511888) PubChem (494431191) Thera-SAbDab YAbS

Avg A4D Score

-0.6361

Score Range

-0.65 to -0.63

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB054_7n0u_H_L	7n0u	100%	-0.6255	6.5	9.0	-0.2207	-0.6716
A4DAB054_7mxl_A_B	7mxl	100%	-0.6466	6.5	9.0	-0.2831	-0.6897