Global Registry
A4D-Ab
Donzakimig1
A4DAB089
|
Phase-I/II
Target
IL22;ALB
Isotype / Subclass
G1;non-canonical / None
Company
UCB Biopharma
Clinical Status
Phase-I/II
Format
Trispecific (G1(VH-CH1-h)-scFv_L-kappa-scFv); Bispecific entry
Synonyms
UCB-1381
UCB 1381
UCB1381
pH Formulation
—
IMGT
PubChem (485663823)
PubChem (494431019)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6867
Score Range
-0.71 to -0.67
Structures
2
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB089_5fuo_H_L
5fuo
99%
-0.6669
6.5
9.0
-0.3438
-0.71
A4DAB089_5fuz_H_L
5fuz
99%
-0.7065
6.5
9.0
-0.4003
-0.7468