Empasiprubart

A4DAB103 | Immune-mediated / inflammatory disorders | Phase-III
C2
G1 / IgG1
arGEN-X Broteio
Phase-III
Whole mAb
ARGX-117 ARGX117
—
IMGT PubChem (471298999) PubChem (474493504) PubChem (485483270) PubChem (485511852) PubChem (494431087) Thera-SAbDab YAbS
Avg A4D Score
-0.7491
Score Range
-0.76 to -0.73
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB103_8acf_H_L 8acf 100% -0.7348 6.5 4.0 -0.6285 -0.7484
A4DAB103_8aci_H_L 8aci 100% -0.7635 6.5 4.0 -0.6788 -0.7742