Epcoritamab

A4DAB106 | Cancer | Approved
CD3E;MS4A1/CD20
G1;G1 / IgG1
Genmab
Approved
Bispecific mAb
ABBV-GMAB-3013 EPKINLY GEN-3013 GEN3013 ABBV3013 ABBV-3013 Tepkinly
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IMGT PubChem (402425939) PubChem (440816811) PubChem (442064636) PubChem (472420475) PubChem (482320770) PubChem (482321847) PubChem (483928971) PubChem (513904629) Thera-SAbDab YAbS
Avg A4D Score
-0.701
Score Range
-0.71 to -0.69
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB106_6y92_H_L 6y92 98% -0.702 7.0 4.0 -0.1958 -0.7677
A4DAB106_6y92_C_D 6y92 98% -0.7117 7.0 4.0 -0.2257 -0.7747
A4DAB106_3giz_H_L 3giz 98% -0.6894 6.5 4.0 -0.1793 -0.7556