Garadacimab

A4DAB125 | Cardiovascular / hemostasis disorders | Approved
F12
G4 / IgG4
CSL Behring
Approved
Whole mAb
CSL 312 CSL312 CSL-312
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IMGT PubChem (381609316) PubChem (472421284) PubChem (476262930) PubChem (476269559) PubChem (496703372) PubChem (505635350) Thera-SAbDab YAbS
Avg A4D Score
-0.5753
Score Range
-0.58 to -0.57
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB125_8r8d_H_L 8r8d 100% -0.5762 6.5 4.0 N/A N/A
A4DAB125_8r8d_E_I 8r8d 100% -0.5744 6.5 4.0 N/A N/A