Larcaviximab

A4DAB152 | Phase-II
Zaire Ebolavirus Glycoprotein
G1 / None
Mapp Biopharmaceutical Public Health Agency of Canada National Institute of Allergy and Infectious Diseases
Phase-II
Whole mAb
c4G7-N
—
IMGT PubChem (374364093) PubChem (381127998) PubChem (472408642) PubChem (480403123) PubChem (481987979) PubChem (513907199) Thera-SAbDab YAbS
Avg A4D Score
-0.6227
Score Range
-0.64 to -0.61
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB152_5ken_G_H 5ken 100% -0.6166 6.5 9.0 -0.0065 -0.7734
A4DAB152_5ken_N_O 5ken 100% -0.6094 6.5 9.0 0.002 -0.7665
A4DAB152_5ken_C_D 5ken 100% -0.6422 6.5 9.0 -0.0335 -0.7987