Maftivimab

A4DAB164 | Preregistration
Zaire Ebolavirus Glycoprotein
G1 / None
Regeneron Pharmaceuticals
Preregistration
Whole mAb
REGN 3479 REGN-3479 REGN3479 INMAZEB (combination with Atoltivimab and Odesivimab)
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IMGT PubChem (381609201) PubChem (404720351) PubChem (472407655) PubChem (480403145) PubChem (481988008) PubChem (505796173) PubChem (508534650) PubChem (513907217) Thera-SAbDab YAbS
Avg A4D Score
-0.5092
Score Range
-0.54 to -0.48
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB164_7tn9_M_N 7tn9 100% -0.4843 6.5 4.0 -0.0429 -0.596
A4DAB164_7tn9_Q_R 7tn9 100% -0.5375 6.5 4.0 -0.1491 -0.634
A4DAB164_7tn9_O_P 7tn9 100% -0.5058 6.5 4.0 -0.0952 -0.6108