Mevonlerbart

A4DAB170 | Phase-III

Target Fel d 1

Isotype / Subclass G4 / None

Company

Regeneron

Clinical Status Phase-III

Format Whole mAb

Synonyms

REGN-1909 REGN1909 REGN1908-1909 (cocktail with Freneslerbart)

pH Formulation —

IMGT PubChem (471299213) PubChem (472420380) PubChem (485483313) PubChem (485511886) PubChem (494431037) Thera-SAbDab YAbS

Avg A4D Score

-0.6969

Score Range

-0.72 to -0.67

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB170_5vyf_B_A	5vyf	100%	-0.6712	6.5	4.0	-0.3972	-0.702
A4DAB170_5vyf_H_L	5vyf	100%	-0.7226	6.5	4.0	-0.4464	-0.7533