Global Registry
A4D-Ab
Renvistobart
A4DAB224
|
Phase-II
Target
TIGIT/WUCAM/VSTM3
Isotype / Subclass
G1 / None
Company
Bristol-Myers Squibb
Compugen
Multiple Myeloma Research Consortium
Ono Pharmaceutical
Clinical Status
Phase-II
Format
Whole mAb
Synonyms
BMS-986207
BMS 986207
BMS986207
pH Formulation
—
IMGT
PubChem (404720502)
PubChem (472411723)
PubChem (485483333)
PubChem (485511901)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6157
Score Range
-0.62 to -0.61
Structures
2
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB224_8szy_H_L
8szy
100%
-0.6217
6.5
4.0
-0.0264
-0.7144
A4DAB224_8szy_I_M
8szy
100%
-0.6096
6.5
4.0
-0.0515
-0.6967