Sabestomig

A4DAB233 | Phase-II
PDCD1/CD279/PD1;HAVCR2/TIM3
G1;G1 / None
AstraZeneca
Phase-II
Bispecific mAb
AZD7789 AZD-7789
—
IMGT PubChem (478838692) PubChem (494431265) Thera-SAbDab YAbS
Avg A4D Score
-0.6859
Score Range
-0.69 to -0.69
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB233_8tft_I_M 8tft 99% -0.6851 6.5 9.0 -0.3747 -0.7264
A4DAB233_8tft_H_L 8tft 99% -0.6867 6.5 4.0 -0.3943 -0.7253