Tamrintamab

A4DAB254 | Phase-I
DPEP3
G1 / None
Stemcentrx
Phase-I
Whole mAb ADC
SC-003 SC003 SC 003 SC-3 SC3 SC 3 SC34.28ss1
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IMGT PubChem (381608702) PubChem (472408684) PubChem (476262836) PubChem (476269496) Thera-SAbDab YAbS
Avg A4D Score
-0.6566
Score Range
-0.66 to -0.65
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB254_6vgr_C_D 6vgr 100% -0.6527 6.5 4.0 -0.1378 -0.7218
A4DAB254_6vgr_H_L 6vgr 100% -0.6605 6.5 4.0 -0.1157 -0.7337