Sonelokimab1

A4DAB269 | Phase-III
IL17A;ALB
non-canonical / None
Ablynx Avillion MoonLake Immunotherapeutics Merck Serono
Phase-III
Whole mAb
ALX 0761 ALX-0761 ALX0761 ALX-761 ALX761 ALX 761 M 1095 M1095 M-1095 MSB-0010841 MSB 0010841 MSB0010841 MSB10841 MSB-10841 MSB 10841 Sonelokinab
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IMGT PubChem (385612250) PubChem (402425678) PubChem (404719351) PubChem (472419685) PubChem (476262731) PubChem (476269339) PubChem (481155518) Thera-SAbDab YAbS
Avg A4D Score
-0.6823
Score Range
-0.71 to -0.66
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB269_7bxa_B_C 7bxa 100% -0.6756 6.5 4.0 -0.1624 -0.7363
A4DAB269_7cgw_H_L 7cgw 100% -0.6842 6.5 4.0 -0.1218 -0.7498
A4DAB269_7bxa_H_L 7bxa 100% -0.7091 6.5 9.0 -0.146 -0.7764
A4DAB269_7cgw_A_B 7cgw 100% -0.6603 6.5 4.0 -0.1668 -0.7177