Vonlerolizumab

A4DAB300 | Phase-II
TNFRSF4/CD134/OX40
G1 / None
Genentech
Phase-II
Whole mAb
MOXR-0916 MOXR0916 MOXR 0916 MOXR-916 MOXR916 MOXR 916 Pogalizumab RG 7888 RG7888 RG-7888
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IMGT PubChem (315661320) PubChem (374364247) PubChem (381127831) PubChem (472408746) PubChem (472435566) PubChem (472439864) PubChem (497983004) Thera-SAbDab YAbS
Avg A4D Score
-0.7543
Score Range
-0.78 to -0.74
Structures
5
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB300_7yk4_H_L 7yk4 100% -0.7415 6.5 4.0 -0.642 -0.7529
A4DAB300_6okn_C_D 6okn 100% -0.7603 6.5 4.0 -0.6001 -0.7785
A4DAB300_7yk4_I_M 7yk4 100% -0.7491 6.5 4.0 -0.6449 -0.7587
A4DAB300_6okn_A_B 6okn 100% -0.7446 6.5 4.0 -0.7042 -0.7492
A4DAB300_6ogx_C_D 6ogx 100% -0.7761 6.5 4.0 -0.7293 -0.7814