A server for prediction of aggregation propensity in protein structures and rational design of protein solubility. In dynamic mode, A3D takes into account the flexibility of natural and designed polypeptides.
Papers describing Aggrescan3D development and applications:
Nucleic Acids Research, 47: W300-W307, 2019 Bioinformatics, btz143, 2019
Molecular Pharmaceutics, 15: 3846-3859, 2018
Nucleic Acids Research, 43: W306-W313, 2015