Bexatamig

A4DAB045 | Phase-I/II
IL3RA/CD123;NCR1/NKP46/NKp46/LY94/CD335
G1;G1 / None
Innate Pharma
Phase-I/II
Bispecific (H-gamma1-VH-G1CH1h_L-kappa)_L-kappa-G1hCH2CH3
NKp46-1 IPH-6101 IPH 6101 IPH6101 SAR-443579 SAR 443579 SAR443579 SAR’579
—
IMGT PubChem (496141639) PubChem (520377151) Thera-SAbDab YAbS
Avg A4D Score
-0.7355
Score Range
-0.78 to -0.7
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB045_6ias_H_L 6ias 100% -0.7594 6.5 9.0 -0.5553 -0.7846
A4DAB045_4jzj_A_B 4jzj 99% -0.6999 6.5 9.0 -0.258 -0.7616
A4DAB045_4jzj_H_L 4jzj 99% -0.7047 6.5 4.0 -0.3218 -0.7579
A4DAB045_6iap_H_L 6iap 100% -0.7781 6.5 9.0 -0.6564 -0.793