Crexavibart

A4DAB075 | Phase-II/III
SARS-CoV-2 Spike RBD
G1 / None
NIAID
Phase-II/III
Whole mAb
C-144-LS BMS-986413 BMS986413 BMS 986413
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IMGT PubChem (472426073) PubChem (476000912) PubChem (485482221) PubChem (485510055) PubChem (513907015) Thera-SAbDab YAbS
Avg A4D Score
-0.5147
Score Range
-0.52 to -0.51
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB075_7k90_M_N 7k90 99% -0.515 6.5 4.0 -0.2945 -0.5931
A4DAB075_7k90_O_P 7k90 99% -0.5174 6.5 4.0 -0.2817 -0.6009
A4DAB075_7k90_H_L 7k90 99% -0.5117 6.5 4.0 -0.2504 -0.6043