Pamlectabart

A4DAB201 | Phase-I/II
TNFRSF17/CD269/BCMA/TNFRSF13A;CD3E
G1 / None
Heidelberg Pharma AG
Phase-I/II
Whole mAb
J22.9 HDP-101 HDP 101 HDP101 HDM-2027 HDM 2027 HDM2027
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IMGT PubChem (507427879) PubChem (520377225) Thera-SAbDab YAbS
Avg A4D Score
-0.6924
Score Range
-0.71 to -0.67
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB201_8qya_H_L 8qya 98% -0.6994 6.5 4.0 -0.2956 -0.7492
A4DAB201_8qyb_H_L 8qyb 100% -0.6708 6.5 4.0 -0.2619 -0.7217
A4DAB201_8qy9_H_L 8qy9 98% -0.707 6.5 4.0 -0.3856 -0.747